Definition Vibrio cholerae O395 chromosome 2, complete sequence.
Accession NC_009457
Length 3,024,069

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The map label for this gene is ftsH [H]

Identifier: 147673292

GI number: 147673292

Start: 168891

End: 170846

Strand: Direct

Name: ftsH [H]

Synonym: VC0395_A0166

Alternate gene names: 147673292

Gene position: 168891-170846 (Clockwise)

Preceding gene: 147673945

Following gene: 147674024

Centisome position: 5.58

GC content: 47.85

Gene sequence:

>1956_bases
TTGAGTGACATGGCAAAAAATTTAATCCTGTGGCTTGTGATTGCTGTCGTTTTGATGTCTGTATTCCAGAGCTTCGGCCC
CGGTGAGAATAACGGCAGAGCAGTCGACTACACCACATTTGTAAAGGAAGTTGGTCAAGGCCAGATTCAGGAAGCTCAAT
TCAACAACGGTGAAATTACTTTCATGCGTCGTGGAGGCGGCAGCCGTTATGTAACTTACATGCCGGTTTATGATCAAAAG
CTCCTCGATGACTTGATCAATCAAGACGTGAAAGTACAAGGTACGCCTCCTGAAGAGCAAAGCTTGCTGGGTACCATTTT
CATCTCTTGGTTCCCAATGATTCTATTGATTGGGGTTTGGATCTTCTTCATGCGTCAAATGCAAGGTGGCGGTGGCAAAG
GTGCCATGTCATTTGGTAAGAGCAAAGCGCGTATGATGAGTGAAGACCAGATAAAAACCACTTTCAGCGACGTTGCGGGC
TGTGATGAAGCAAAAGAAGATGTGAAAGAACTGGTCGATTACCTGCGCGATCCGAGCCGCTTCCAAAAGCTGGGTGGTAA
GATCCCAACGGGTGTACTCATGGTTGGTCCTCCTGGTACAGGTAAAACCTTGCTTGCCAAAGCGATTGCTGGTGAAGCTA
AAGTGCCATTCTTTACTATCTCTGGTTCGGATTTCGTTGAAATGTTTGTCGGTGTCGGTGCATCTCGTGTGCGTGACATG
TTCGAACAAGCGAAGAAAGCCTCTCCATGTATTATTTTCATTGATGAAATTGATGCAGTGGGTCGTCAGCGTGGCGCGGG
TGTTGGTGGTGGTCACGATGAACGTGAGCAGACACTAAACCAAATGCTGGTTGAGATGGATGGTTTTGAAGGCAATGAAG
GCATTATTGTCATCGCGGCAACCAACCGTCCTGACGTGTTGGACCCAGCATTGCTGCGTCCGGGACGTTTTGACCGTCAA
GTCGTGGTAGGCCTGCCAGATGTGCGTGGTCGTGAGCAAATTCTTAAAGTGCATATGCGCAAAGTGCCTCTGGCGAATGA
TGTAGAGCCATCATTGATTGCGCGTGGTACTCCTGGATTCTCTGGTGCGGATTTAGCGAACTTAGTTAACGAAGCGGCGC
TGTTTGCTGCTCGTGGCAACAAGCGCAACGTCTCTATGGTTGAGTTTGAACTTGCAAAAGACAAAATCATGATGGGTGCA
GAGCGCCGTTCAATGGTGATGTCTGAAGAGATAAAAGAGTCTACCGCTTATCATGAGGCTGGTCATGCGGTAGTAGGTCG
CCTTGTACCTGAGCATGATCCGGTTTACAAAGTGTCGATCATTCCTCGCGGTCGTGCATTGGGTGTCACCATGTACTTGC
CTGAGCAAGATCGCGTGAGTATGTCTAAACAGCATCTGGAATCAATGATCTCTAGCTTGTACGGCGGTCGTCTTGCTGAA
GAGTTGATTTACGGCAAAGAGAAAGTTTCAACAGGCGCATCAAACGATATCGAGCGTGCAACAGAAATTGCTCGTAAGAT
GGTGACCCAATGGGGCTTCTCTGAAAAGCTAGGCCCTATGTTGTATGCGGAAGATGAAGGTGAAGTGTTCCTTGGGCGCA
GTGTGACACAGACGAAACACATGTCTGATGACACCGCGAAGCTGATTGATGACGAAGTGCGTCAAATCATTGATCGTAAC
TACGAACGAGCTCGCCAAATCATTATGGATAATATGGATATCATGCATGCGATGAAAGATGCATTGATGAAGTATGAAAC
TATCGATGCAGGTCAGATTGATGACTTGATGGCGCGTAAGCCTGTGATTCGTGAACCAGCAGGTTGGGGTGAACAATCGA
AAACTCCGTCTGCACCTGAAGTAAAAGCTGAGCCTGAAGCTAAGGCGGAAGAATCTACAGCAGAGACTGCTTCATCGGAT
GTCGCGACAGCAAGCGAGAAAAAAGACGCTGAATAA

Upstream 100 bases:

>100_bases
CTATTTCACTATTTGGTGCCTAAGTAGACCCTATAGCCGCTAGCTACAAACTGTAGTACCCTACCTTTTAATTACAATTA
GTTATCGCGAGGCTTACACC

Downstream 100 bases:

>100_bases
CATCACTTTTAACTTTAAACCCCGACTTGTTCGGGGTTTTGTGTTTGCAGGGAATATATTTTTAGAATGCTGAAAATCAG
TCATGCCGATAAGCAGCTTG

Product: cell division protein FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 650

Protein sequence:

>651_residues
MSDMAKNLILWLVIAVVLMSVFQSFGPGENNGRAVDYTTFVKEVGQGQIQEAQFNNGEITFMRRGGGSRYVTYMPVYDQK
LLDDLINQDVKVQGTPPEEQSLLGTIFISWFPMILLIGVWIFFMRQMQGGGGKGAMSFGKSKARMMSEDQIKTTFSDVAG
CDEAKEDVKELVDYLRDPSRFQKLGGKIPTGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDM
FEQAKKASPCIIFIDEIDAVGRQRGAGVGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQ
VVVGLPDVRGREQILKVHMRKVPLANDVEPSLIARGTPGFSGADLANLVNEAALFAARGNKRNVSMVEFELAKDKIMMGA
ERRSMVMSEEIKESTAYHEAGHAVVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRVSMSKQHLESMISSLYGGRLAE
ELIYGKEKVSTGASNDIERATEIARKMVTQWGFSEKLGPMLYAEDEGEVFLGRSVTQTKHMSDDTAKLIDDEVRQIIDRN
YERARQIIMDNMDIMHAMKDALMKYETIDAGQIDDLMARKPVIREPAGWGEQSKTPSAPEVKAEPEAKAEESTAETASSD
VATASEKKDAE

Sequences:

>Translated_651_residues
MSDMAKNLILWLVIAVVLMSVFQSFGPGENNGRAVDYTTFVKEVGQGQIQEAQFNNGEITFMRRGGGSRYVTYMPVYDQK
LLDDLINQDVKVQGTPPEEQSLLGTIFISWFPMILLIGVWIFFMRQMQGGGGKGAMSFGKSKARMMSEDQIKTTFSDVAG
CDEAKEDVKELVDYLRDPSRFQKLGGKIPTGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDM
FEQAKKASPCIIFIDEIDAVGRQRGAGVGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQ
VVVGLPDVRGREQILKVHMRKVPLANDVEPSLIARGTPGFSGADLANLVNEAALFAARGNKRNVSMVEFELAKDKIMMGA
ERRSMVMSEEIKESTAYHEAGHAVVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRVSMSKQHLESMISSLYGGRLAE
ELIYGKEKVSTGASNDIERATEIARKMVTQWGFSEKLGPMLYAEDEGEVFLGRSVTQTKHMSDDTAKLIDDEVRQIIDRN
YERARQIIMDNMDIMHAMKDALMKYETIDAGQIDDLMARKPVIREPAGWGEQSKTPSAPEVKAEPEAKAEESTAETASSD
VATASEKKDAE
>Mature_650_residues
SDMAKNLILWLVIAVVLMSVFQSFGPGENNGRAVDYTTFVKEVGQGQIQEAQFNNGEITFMRRGGGSRYVTYMPVYDQKL
LDDLINQDVKVQGTPPEEQSLLGTIFISWFPMILLIGVWIFFMRQMQGGGGKGAMSFGKSKARMMSEDQIKTTFSDVAGC
DEAKEDVKELVDYLRDPSRFQKLGGKIPTGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMF
EQAKKASPCIIFIDEIDAVGRQRGAGVGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQV
VVGLPDVRGREQILKVHMRKVPLANDVEPSLIARGTPGFSGADLANLVNEAALFAARGNKRNVSMVEFELAKDKIMMGAE
RRSMVMSEEIKESTAYHEAGHAVVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRVSMSKQHLESMISSLYGGRLAEE
LIYGKEKVSTGASNDIERATEIARKMVTQWGFSEKLGPMLYAEDEGEVFLGRSVTQTKHMSDDTAKLIDDEVRQIIDRNY
ERARQIIMDNMDIMHAMKDALMKYETIDAGQIDDLMARKPVIREPAGWGEQSKTPSAPEVKAEPEAKAEESTAETASSDV
ATASEKKDAE

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=509, Percent_Identity=45.3831041257367, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI7657689, Length=440, Percent_Identity=49.5454545454545, Blast_Score=441, Evalue=1e-123,
Organism=Homo sapiens, GI21327685, Length=440, Percent_Identity=49.5454545454545, Blast_Score=441, Evalue=1e-123,
Organism=Homo sapiens, GI4507173, Length=619, Percent_Identity=37.4798061389338, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=42.1259842519685, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI24497435, Length=262, Percent_Identity=41.2213740458015, Blast_Score=209, Evalue=8e-54,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=42.9203539823009, Blast_Score=204, Evalue=3e-52,
Organism=Homo sapiens, GI195539395, Length=253, Percent_Identity=39.5256916996047, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI21361144, Length=240, Percent_Identity=42.9166666666667, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI24430151, Length=254, Percent_Identity=37.7952755905512, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI45643123, Length=285, Percent_Identity=38.2456140350877, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI45643125, Length=285, Percent_Identity=38.2456140350877, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI89064750, Length=264, Percent_Identity=39.0151515151515, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI5729991, Length=264, Percent_Identity=39.0151515151515, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI24430155, Length=264, Percent_Identity=39.0151515151515, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI157671927, Length=237, Percent_Identity=38.3966244725738, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI4505725, Length=213, Percent_Identity=42.2535211267606, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI40806173, Length=301, Percent_Identity=38.5382059800665, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI229577436, Length=256, Percent_Identity=37.890625, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI5901990, Length=233, Percent_Identity=40.7725321888412, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI24497618, Length=273, Percent_Identity=36.6300366300366, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI153792536, Length=286, Percent_Identity=36.013986013986, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI226371754, Length=234, Percent_Identity=38.4615384615385, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI194018488, Length=256, Percent_Identity=38.28125, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI14149767, Length=299, Percent_Identity=33.4448160535117, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI62177112, Length=299, Percent_Identity=33.4448160535117, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI11875211, Length=262, Percent_Identity=38.5496183206107, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI156564401, Length=257, Percent_Identity=36.1867704280156, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI40806170, Length=262, Percent_Identity=38.5496183206107, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI7019569, Length=230, Percent_Identity=36.9565217391304, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI31742536, Length=225, Percent_Identity=37.7777777777778, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI112789543, Length=225, Percent_Identity=37.7777777777778, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI310125280, Length=235, Percent_Identity=37.8723404255319, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI310125282, Length=257, Percent_Identity=35.7976653696498, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI17865802, Length=230, Percent_Identity=37.8260869565217, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI31377644, Length=246, Percent_Identity=34.5528455284553, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI64084766, Length=225, Percent_Identity=32.4444444444444, Blast_Score=106, Evalue=9e-23,
Organism=Homo sapiens, GI116292174, Length=248, Percent_Identity=30.241935483871, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789568, Length=630, Percent_Identity=80.3174603174603, Blast_Score=1042, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994521, Length=471, Percent_Identity=46.7091295116773, Blast_Score=426, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17554264, Length=505, Percent_Identity=43.5643564356436, Blast_Score=416, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI115534323, Length=459, Percent_Identity=44.2265795206972, Blast_Score=369, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17554786, Length=262, Percent_Identity=42.7480916030534, Blast_Score=221, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI25144278, Length=262, Percent_Identity=42.7480916030534, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI25144281, Length=262, Percent_Identity=42.7480916030534, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=261, Percent_Identity=41.7624521072797, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17532375, Length=247, Percent_Identity=41.7004048582996, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17531535, Length=245, Percent_Identity=42.8571428571429, Blast_Score=203, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71987364, Length=254, Percent_Identity=40.1574803149606, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71987372, Length=254, Percent_Identity=40.1574803149606, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17508701, Length=254, Percent_Identity=41.7322834645669, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17563250, Length=254, Percent_Identity=37.4015748031496, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17505546, Length=248, Percent_Identity=39.1129032258064, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=227, Percent_Identity=40.5286343612335, Blast_Score=180, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17554784, Length=245, Percent_Identity=40, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI193206114, Length=248, Percent_Identity=39.1129032258064, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17537217, Length=193, Percent_Identity=43.0051813471503, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI133931034, Length=248, Percent_Identity=39.1129032258064, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=248, Percent_Identity=39.1129032258064, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25153574, Length=248, Percent_Identity=35.8870967741936, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI193209502, Length=224, Percent_Identity=37.5, Blast_Score=153, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=46.6666666666667, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=46.6666666666667, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25146157, Length=256, Percent_Identity=37.890625, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17562804, Length=228, Percent_Identity=38.1578947368421, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI133901662, Length=212, Percent_Identity=40.5660377358491, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI133901658, Length=212, Percent_Identity=40.5660377358491, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI86561515, Length=244, Percent_Identity=34.4262295081967, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32563584, Length=241, Percent_Identity=36.9294605809129, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508421, Length=241, Percent_Identity=36.9294605809129, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17541224, Length=233, Percent_Identity=36.0515021459227, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541226, Length=233, Percent_Identity=36.0515021459227, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17560432, Length=230, Percent_Identity=35.6521739130435, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71990294, Length=197, Percent_Identity=30.4568527918782, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325281, Length=495, Percent_Identity=46.0606060606061, Blast_Score=468, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6320854, Length=523, Percent_Identity=45.1242829827916, Blast_Score=445, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6323736, Length=533, Percent_Identity=44.6529080675422, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6322704, Length=261, Percent_Identity=41.7624521072797, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6320077, Length=247, Percent_Identity=42.1052631578947, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6321390, Length=254, Percent_Identity=40.9448818897638, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6324691, Length=251, Percent_Identity=41.4342629482072, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=242, Percent_Identity=41.7355371900826, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320197, Length=245, Percent_Identity=37.9591836734694, Blast_Score=187, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6324000, Length=251, Percent_Identity=40.6374501992032, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6320602, Length=242, Percent_Identity=40.9090909090909, Blast_Score=174, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=212, Percent_Identity=39.622641509434, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321709, Length=234, Percent_Identity=41.8803418803419, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323429, Length=227, Percent_Identity=40.9691629955947, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322651, Length=245, Percent_Identity=35.1020408163265, Blast_Score=163, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6321465, Length=239, Percent_Identity=38.0753138075314, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6325431, Length=226, Percent_Identity=38.4955752212389, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319554, Length=213, Percent_Identity=39.4366197183099, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6325183, Length=238, Percent_Identity=36.1344537815126, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320887, Length=248, Percent_Identity=33.8709677419355, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6320583, Length=282, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24658770, Length=485, Percent_Identity=45.979381443299, Blast_Score=446, Evalue=1e-125,
Organism=Drosophila melanogaster, GI28574878, Length=501, Percent_Identity=45.5089820359281, Blast_Score=438, Evalue=1e-123,
Organism=Drosophila melanogaster, GI24665814, Length=501, Percent_Identity=45.5089820359281, Blast_Score=438, Evalue=1e-123,
Organism=Drosophila melanogaster, GI24639391, Length=456, Percent_Identity=44.2982456140351, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI17137560, Length=286, Percent_Identity=39.8601398601399, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI161076486, Length=285, Percent_Identity=40, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI161076488, Length=286, Percent_Identity=39.8601398601399, Blast_Score=223, Evalue=4e-58,
Organism=Drosophila melanogaster, GI17137738, Length=254, Percent_Identity=42.9133858267717, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI19920408, Length=262, Percent_Identity=41.2213740458015, Blast_Score=210, Evalue=3e-54,
Organism=Drosophila melanogaster, GI45554047, Length=163, Percent_Identity=57.6687116564417, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI24651451, Length=262, Percent_Identity=41.2213740458015, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24652279, Length=273, Percent_Identity=38.8278388278388, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24660075, Length=235, Percent_Identity=42.9787234042553, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI281365776, Length=235, Percent_Identity=42.9787234042553, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI45552965, Length=235, Percent_Identity=42.9787234042553, Blast_Score=199, Evalue=7e-51,
Organism=Drosophila melanogaster, GI19921202, Length=243, Percent_Identity=41.1522633744856, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24649446, Length=254, Percent_Identity=38.5826771653543, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24640100, Length=253, Percent_Identity=39.5256916996047, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI17738151, Length=239, Percent_Identity=41.8410041841004, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24663015, Length=253, Percent_Identity=38.7351778656126, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281361487, Length=252, Percent_Identity=40.0793650793651, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI18860063, Length=239, Percent_Identity=40.1673640167364, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24656820, Length=239, Percent_Identity=38.9121338912134, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24656825, Length=239, Percent_Identity=39.3305439330544, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281363136, Length=235, Percent_Identity=38.2978723404255, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI78707192, Length=235, Percent_Identity=38.2978723404255, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21355121, Length=205, Percent_Identity=37.0731707317073, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24644145, Length=238, Percent_Identity=37.3949579831933, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI20129529, Length=274, Percent_Identity=34.3065693430657, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI18859657, Length=251, Percent_Identity=38.2470119521912, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281360142, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI21357333, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360144, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360140, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360146, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360138, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281360136, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24644411, Length=228, Percent_Identity=36.8421052631579, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571849, Length=230, Percent_Identity=40, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28571847, Length=230, Percent_Identity=40, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24581396, Length=232, Percent_Identity=39.2241379310345, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17864540, Length=214, Percent_Identity=40.1869158878505, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28573010, Length=214, Percent_Identity=40.1869158878505, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI20129423, Length=233, Percent_Identity=34.3347639484979, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24639486, Length=194, Percent_Identity=36.0824742268041, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 71705; Mature: 71574

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSDMAKNLILWLVIAVVLMSVFQSFGPGENNGRAVDYTTFVKEVGQGQIQEAQFNNGEIT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCCEECCCCCCCCEE
FMRRGGGSRYVTYMPVYDQKLLDDLINQDVKVQGTPPEEQSLLGTIFISWFPMILLIGVW
EEEECCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
IFFMRQMQGGGGKGAMSFGKSKARMMSEDQIKTTFSDVAGCDEAKEDVKELVDYLRDPSR
HHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHH
FQKLGGKIPTGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDM
HHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHH
FEQAKKASPCIIFIDEIDAVGRQRGAGVGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAA
HHHHHCCCCEEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEE
TNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRKVPLANDVEPSLIARGTPGF
CCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHEECCCCCC
SGADLANLVNEAALFAARGNKRNVSMVEFELAKDKIMMGAERRSMVMSEEIKESTAYHEA
CCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
GHAVVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRVSMSKQHLESMISSLYGGRLAE
HHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHH
ELIYGKEKVSTGASNDIERATEIARKMVTQWGFSEKLGPMLYAEDEGEVFLGRSVTQTKH
HHHHCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCCEEECCCHHHHHC
MSDDTAKLIDDEVRQIIDRNYERARQIIMDNMDIMHAMKDALMKYETIDAGQIDDLMARK
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
PVIREPAGWGEQSKTPSAPEVKAEPEAKAEESTAETASSDVATASEKKDAE
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDMAKNLILWLVIAVVLMSVFQSFGPGENNGRAVDYTTFVKEVGQGQIQEAQFNNGEIT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHCCCCEECCCCCCCCEE
FMRRGGGSRYVTYMPVYDQKLLDDLINQDVKVQGTPPEEQSLLGTIFISWFPMILLIGVW
EEEECCCCEEEEEECCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
IFFMRQMQGGGGKGAMSFGKSKARMMSEDQIKTTFSDVAGCDEAKEDVKELVDYLRDPSR
HHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHH
FQKLGGKIPTGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDM
HHHHCCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHH
FEQAKKASPCIIFIDEIDAVGRQRGAGVGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAA
HHHHHCCCCEEEEEECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEE
TNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRKVPLANDVEPSLIARGTPGF
CCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHEECCCCCC
SGADLANLVNEAALFAARGNKRNVSMVEFELAKDKIMMGAERRSMVMSEEIKESTAYHEA
CCHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
GHAVVGRLVPEHDPVYKVSIIPRGRALGVTMYLPEQDRVSMSKQHLESMISSLYGGRLAE
HHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHH
ELIYGKEKVSTGASNDIERATEIARKMVTQWGFSEKLGPMLYAEDEGEVFLGRSVTQTKH
HHHHCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCEEEECCCCCEEECCCHHHHHC
MSDDTAKLIDDEVRQIIDRNYERARQIIMDNMDIMHAMKDALMKYETIDAGQIDDLMARK
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHCC
PVIREPAGWGEQSKTPSAPEVKAEPEAKAEESTAETASSDVATASEKKDAE
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA