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The map label for this gene is blh [H]

Identifier: 146343614

GI number: 146343614

Start: 7113632

End: 7114672

Strand: Direct

Name: blh [H]

Synonym: BRADO6852

Alternate gene names: 146343614

Gene position: 7113632-7114672 (Clockwise)

Preceding gene: 146343613

Following gene: 146343615

Centisome position: 95.4

GC content: 64.84

Gene sequence:

>1041_bases
ATGATCTTCCGCCAATTGTTCGACAGCGTCTCCGGCACTTACAGCTACATTCTTGCGAGCCGCTCCGGCGGCGAGGCTGT
CATCATCGATCCCGTGCTGGAGAAGGTCGACCGCTATTGCCAGCTGCTGCGCGAGCTCGACTTGCGCCTGGTCAAGGCGA
TCGACACCCATTTGCATGCCGATCACGTCACCGGCCTCGGCGCGCTGCGTGACCGCACTCATTGCGTCACCATCATGGGC
GAGCAGACCAAGGCGGACGTGGTGGCGATGCGCGTCGGCGAAGGCGACAGGATCGCCATCGAGGGTCTCAGCCTCGATGT
GATTTACACGCCGGGGCACACTGACGATTCCTACAGCTTCCTGATGGCCGACCGGGTCTTCACCGGCGACACGCTGCTGA
TCCGCGGCACCGGCCGCACCGACTTCCAGAACGGCGACGCCCGGCAGCAATATGATTCGATTTTCAACAAGCTGCTGCGG
CTGCCCGATGACACGCTGGTCTACCCCGCGCACGACTACAAGGGCGACACCGTTTCCACGATCGGCGAGGAGCGCCGCTA
CAATCCGCGGCTTCAGGTGCAATCCGTCGACGATTACGTGGCGCTGATGGCCAAGCTGAAGCTGCCGAACCCGAAGATGA
TGGACGTCGCCGTGCCAGCCAACATGCGCGTCGGGCTGCATCAGGAGGAGCTGACCAGACAGGGCCTGGCCCTGTCGGCC
CGAGAAGCGATCGAATGCCTCGGACGGCCCGACGTGCTGCTGGTCGATCTGCGCGAGGCTTCGGAGCGCGCCAAGCACGG
CACGCTGTCAGGCGCGCTGCATGCGCCCTACCCTGGGATCGCCGACAATCTCAAACCCGGCGGCATGCTGCGCGAGGTTG
CCGCCGCCACCGGGCGCCGCATCGTGTTCTTCTGCGCCTATGGCGAACGCTCGGCCATGGCCGTTCAGACGGCGCAAGAC
GCGGGCTTGGCCAACACCGCGCACATCGAGGGCGGACTCGATGCATGGAAGAAGGCCGGTGGACCGGTGGTTGCAGGGTA
G

Upstream 100 bases:

>100_bases
CCGAATGGCGCACCGCAACGACGCTGCTTCGGCGCCGCATGGATGACCGCGGCCCGACCGTGGTCTAAACCGGCCTCGAT
CCGAATCGGGAGGAAGCGCG

Downstream 100 bases:

>100_bases
ACGCGAAACAAGCTGCGCCATGAACCCGCCGCGATGGACGCCAACTGTCGCCGGCGTCAAGATGCGGTTCGAGTGGCCAC
GATTGTCGTGCCAATCGGCT

Product: bifunctional glyoxylase/rhodanese-like sulfurtransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MIFRQLFDSVSGTYSYILASRSGGEAVIIDPVLEKVDRYCQLLRELDLRLVKAIDTHLHADHVTGLGALRDRTHCVTIMG
EQTKADVVAMRVGEGDRIAIEGLSLDVIYTPGHTDDSYSFLMADRVFTGDTLLIRGTGRTDFQNGDARQQYDSIFNKLLR
LPDDTLVYPAHDYKGDTVSTIGEERRYNPRLQVQSVDDYVALMAKLKLPNPKMMDVAVPANMRVGLHQEELTRQGLALSA
REAIECLGRPDVLLVDLREASERAKHGTLSGALHAPYPGIADNLKPGGMLREVAAATGRRIVFFCAYGERSAMAVQTAQD
AGLANTAHIEGGLDAWKKAGGPVVAG

Sequences:

>Translated_346_residues
MIFRQLFDSVSGTYSYILASRSGGEAVIIDPVLEKVDRYCQLLRELDLRLVKAIDTHLHADHVTGLGALRDRTHCVTIMG
EQTKADVVAMRVGEGDRIAIEGLSLDVIYTPGHTDDSYSFLMADRVFTGDTLLIRGTGRTDFQNGDARQQYDSIFNKLLR
LPDDTLVYPAHDYKGDTVSTIGEERRYNPRLQVQSVDDYVALMAKLKLPNPKMMDVAVPANMRVGLHQEELTRQGLALSA
REAIECLGRPDVLLVDLREASERAKHGTLSGALHAPYPGIADNLKPGGMLREVAAATGRRIVFFCAYGERSAMAVQTAQD
AGLANTAHIEGGLDAWKKAGGPVVAG
>Mature_346_residues
MIFRQLFDSVSGTYSYILASRSGGEAVIIDPVLEKVDRYCQLLRELDLRLVKAIDTHLHADHVTGLGALRDRTHCVTIMG
EQTKADVVAMRVGEGDRIAIEGLSLDVIYTPGHTDDSYSFLMADRVFTGDTLLIRGTGRTDFQNGDARQQYDSIFNKLLR
LPDDTLVYPAHDYKGDTVSTIGEERRYNPRLQVQSVDDYVALMAKLKLPNPKMMDVAVPANMRVGLHQEELTRQGLALSA
REAIECLGRPDVLLVDLREASERAKHGTLSGALHAPYPGIADNLKPGGMLREVAAATGRRIVFFCAYGERSAMAVQTAQD
AGLANTAHIEGGLDAWKKAGGPVVAG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=230, Percent_Identity=46.9565217391304, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI94538322, Length=192, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI94538320, Length=192, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI7705793, Length=181, Percent_Identity=28.1767955801105, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787158, Length=191, Percent_Identity=31.413612565445, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538952, Length=223, Percent_Identity=43.0493273542601, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17536925, Length=246, Percent_Identity=26.8292682926829, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330176, Length=231, Percent_Identity=47.6190476190476, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24667703, Length=254, Percent_Identity=26.3779527559055, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667711, Length=254, Percent_Identity=26.3779527559055, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356335, Length=254, Percent_Identity=25.5905511811024, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 37823; Mature: 37823

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFRQLFDSVSGTYSYILASRSGGEAVIIDPVLEKVDRYCQLLRELDLRLVKAIDTHLHA
CCHHHHHHHHCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DHVTGLGALRDRTHCVTIMGEQTKADVVAMRVGEGDRIAIEGLSLDVIYTPGHTDDSYSF
HHHCCCHHHCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEEEEEEEECCCCCCCCCEE
LMADRVFTGDTLLIRGTGRTDFQNGDARQQYDSIFNKLLRLPDDTLVYPAHDYKGDTVST
EEECEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHH
IGEERRYNPRLQVQSVDDYVALMAKLKLPNPKMMDVAVPANMRVGLHQEELTRQGLALSA
HHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCHHHHHHCCCCHHH
REAIECLGRPDVLLVDLREASERAKHGTLSGALHAPYPGIADNLKPGGMLREVAAATGRR
HHHHHHCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCE
IVFFCAYGERSAMAVQTAQDAGLANTAHIEGGLDAWKKAGGPVVAG
EEEEEECCCCCEEEEEEHHCCCCCCEEEECCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MIFRQLFDSVSGTYSYILASRSGGEAVIIDPVLEKVDRYCQLLRELDLRLVKAIDTHLHA
CCHHHHHHHHCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DHVTGLGALRDRTHCVTIMGEQTKADVVAMRVGEGDRIAIEGLSLDVIYTPGHTDDSYSF
HHHCCCHHHCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEEEEEEEECCCCCCCCCEE
LMADRVFTGDTLLIRGTGRTDFQNGDARQQYDSIFNKLLRLPDDTLVYPAHDYKGDTVST
EEECEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHH
IGEERRYNPRLQVQSVDDYVALMAKLKLPNPKMMDVAVPANMRVGLHQEELTRQGLALSA
HHHHHCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCHHHHHHCCCCHHH
REAIECLGRPDVLLVDLREASERAKHGTLSGALHAPYPGIADNLKPGGMLREVAAATGRR
HHHHHHCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCE
IVFFCAYGERSAMAVQTAQDAGLANTAHIEGGLDAWKKAGGPVVAG
EEEEEECCCCCEEEEEEHHCCCCCCEEEECCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]