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The map label for this gene is corA [H]

Identifier: 146343421

GI number: 146343421

Start: 6904931

End: 6905944

Strand: Reverse

Name: corA [H]

Synonym: BRADO6650

Alternate gene names: 146343421

Gene position: 6905944-6904931 (Counterclockwise)

Preceding gene: 146343422

Following gene: 146343418

Centisome position: 92.62

GC content: 67.55

Gene sequence:

>1014_bases
ATGCGCCACGTCACAATCCAGTCACCGGCCGACGCGCGTCGCGAGCCTGGCGTGGTCGCGGCCGGCGTTTATGCCAACGG
CCGCCGCGTCGCCGATATCGCGATCGACGAGGCCGGCGCATGGAGCCGCAAGCCGGGACATGTCGTCTGGATCGGGCTGC
ACGAGCCGGATGCGGCGCTGCTGCAGCGGATCGCCGATCAGTTCAACCTGCATGAGCTCGCGATCGAGGACGCCTCTAAG
GCGCATCAGCAGCCGAAGGTCGAGCGCTATGGTGATGCGCTGTTCGTCGTCGCGCGCACCGCGCAGCTCGTCAAGGAGCA
CATCATCTTCGGTGAGACCCATATCTTCGTCGGCCCCGGTTTCGTCGTGTCGGTGCGGCACGGCGCCTCGACCTCCTATG
GCGCGGTGCGCGAGCGCTGCGAGAGCTGCCCGGGCTCGCTCGCCAAGGGCGAGGACTACATCCTCTATGCGATCCTCGAT
TTCATCGTCGACAACTACCGCCCCGTCACCGAGAGCATCATGGCCGAGGTCGAGACCCTGGAGGAGGTCGTGCTGCAGCG
GCCGCTGGCGCGCCACGAGGTGGACCGGCTCTATCGTCTCAGGCGCGACCTGCTGCGGCTCCGCCGCGCCGTCGGCCCCG
TGGTCGACGTCTGCAAGCGGCTGGAACATGTCGACAATGTCGCGATCGACGCCGAGATGGCGCCGCTGTTCCGCGACGTG
CTCGACCATGCCAAGCGCGCCGAGGAGGATGCGGATTCGCTGCGCGAGATCCTCGCCTTCGTGTTCGAGGCCAGCATGAT
GGCGGGACAGGCGCAGCAGACCGACATCGCCCGCCGCCTGGCGGCCTGGGCCGCGATCCTCGCGGTGCCGACGGCGGTGG
CCGGCATCTACGGCATGAATTTCGAGCACATGCCGGAGCTGAAATGGCAGTACGGCTACTACGCCGTGCTCGGCTTCATT
GCGGTCGTCTGCAGCACGCTGTACTGGCAGTTCCGCCGCCGCGGGTGGCTGTGA

Upstream 100 bases:

>100_bases
TCCGGCAGTTGCTCGACGGCCCGACCGGCGTGACCTGATGCAGCGCTTGACCCGGCGACTCCTCGCGTCGAAAGTCGCTG
TCGAGAGCGGAGAACCCGGC

Downstream 100 bases:

>100_bases
GGGGCGCACCGCGAGCCGAACTAAATCTCACTTGTTCATTGCAACACTCTGCGAGCCCCAACTACGGTGCACCCTCTCCC
CTTGTGGGAGAGGGTGGCTT

Product: putative metal ion transporter Mg2+ transporter protein (CorA-like)

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRHVTIQSPADARREPGVVAAGVYANGRRVADIAIDEAGAWSRKPGHVVWIGLHEPDAALLQRIADQFNLHELAIEDASK
AHQQPKVERYGDALFVVARTAQLVKEHIIFGETHIFVGPGFVVSVRHGASTSYGAVRERCESCPGSLAKGEDYILYAILD
FIVDNYRPVTESIMAEVETLEEVVLQRPLARHEVDRLYRLRRDLLRLRRAVGPVVDVCKRLEHVDNVAIDAEMAPLFRDV
LDHAKRAEEDADSLREILAFVFEASMMAGQAQQTDIARRLAAWAAILAVPTAVAGIYGMNFEHMPELKWQYGYYAVLGFI
AVVCSTLYWQFRRRGWL

Sequences:

>Translated_337_residues
MRHVTIQSPADARREPGVVAAGVYANGRRVADIAIDEAGAWSRKPGHVVWIGLHEPDAALLQRIADQFNLHELAIEDASK
AHQQPKVERYGDALFVVARTAQLVKEHIIFGETHIFVGPGFVVSVRHGASTSYGAVRERCESCPGSLAKGEDYILYAILD
FIVDNYRPVTESIMAEVETLEEVVLQRPLARHEVDRLYRLRRDLLRLRRAVGPVVDVCKRLEHVDNVAIDAEMAPLFRDV
LDHAKRAEEDADSLREILAFVFEASMMAGQAQQTDIARRLAAWAAILAVPTAVAGIYGMNFEHMPELKWQYGYYAVLGFI
AVVCSTLYWQFRRRGWL
>Mature_337_residues
MRHVTIQSPADARREPGVVAAGVYANGRRVADIAIDEAGAWSRKPGHVVWIGLHEPDAALLQRIADQFNLHELAIEDASK
AHQQPKVERYGDALFVVARTAQLVKEHIIFGETHIFVGPGFVVSVRHGASTSYGAVRERCESCPGSLAKGEDYILYAILD
FIVDNYRPVTESIMAEVETLEEVVLQRPLARHEVDRLYRLRRDLLRLRRAVGPVVDVCKRLEHVDNVAIDAEMAPLFRDV
LDHAKRAEEDADSLREILAFVFEASMMAGQAQQTDIARRLAAWAAILAVPTAVAGIYGMNFEHMPELKWQYGYYAVLGFI
AVVCSTLYWQFRRRGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=234, Percent_Identity=25.6410256410256, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37857; Mature: 37857

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVTIQSPADARREPGVVAAGVYANGRRVADIAIDEAGAWSRKPGHVVWIGLHEPDAAL
CCEEECCCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCEEEEEECCCCHHH
LQRIADQFNLHELAIEDASKAHQQPKVERYGDALFVVARTAQLVKEHIIFGETHIFVGPG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCC
FVVSVRHGASTSYGAVRERCESCPGSLAKGEDYILYAILDFIVDNYRPVTESIMAEVETL
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EEVVLQRPLARHEVDRLYRLRRDLLRLRRAVGPVVDVCKRLEHVDNVAIDAEMAPLFRDV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEECHHHHHHHHHH
LDHAKRAEEDADSLREILAFVFEASMMAGQAQQTDIARRLAAWAAILAVPTAVAGIYGMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FEHMPELKWQYGYYAVLGFIAVVCSTLYWQFRRRGWL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRHVTIQSPADARREPGVVAAGVYANGRRVADIAIDEAGAWSRKPGHVVWIGLHEPDAAL
CCEEECCCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCEEEEEECCCCHHH
LQRIADQFNLHELAIEDASKAHQQPKVERYGDALFVVARTAQLVKEHIIFGETHIFVGPG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCC
FVVSVRHGASTSYGAVRERCESCPGSLAKGEDYILYAILDFIVDNYRPVTESIMAEVETL
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EEVVLQRPLARHEVDRLYRLRRDLLRLRRAVGPVVDVCKRLEHVDNVAIDAEMAPLFRDV
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEECHHHHHHHHHH
LDHAKRAEEDADSLREILAFVFEASMMAGQAQQTDIARRLAAWAAILAVPTAVAGIYGMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FEHMPELKWQYGYYAVLGFIAVVCSTLYWQFRRRGWL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]