BacMap

Definition	Bradyrhizobium sp. ORS278 chromosome, complete genome.
Accession	NC_009445
Length	7,456,587

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The map label for this gene is rbtD [H]

Identifier: 146343418

GI number: 146343418

Start: 6900808

End: 6901536

Strand: Reverse

Name: rbtD [H]

Synonym: BRADO6647

Alternate gene names: 146343418

Gene position: 6901536-6900808 (Counterclockwise)

Preceding gene: 146343421

Following gene: 146343413

Centisome position: 92.56

GC content: 67.63

Gene sequence:

>729_bases
ATGGGCAGGGAACTCGAGGGCAAGGTGGCTGCCGTCACCGGCGCGGCGTCGGGCATCGGGCTCGCGAGCAGCGAGGCGAT
GCTGGCCGCCGGCGCGCGCGTCGTGATGATCGATCGCGATGCCGCGGCGCTGGCGCGCCTGCGCGAGCAGCACGGCGAGG
CAATCATTCCGGTGGTCATCGACCTGCTCGATCCCACGGATTGCGCCACGCTGCTGCCTCGCGTGCTGGACGCAGCCGGC
CGGCTCGACATCTTCCACGCCAATGCCGGCAGCTATCTTGGCGGCGACCTGGTCGATGCCAGGACGGACGCGATCGACCG
CATGCTCCATCTCAATATCAACGTCGTCATGAAGAACGTCCGCGACGTGCTCCCGCACATGATCGCGCGCGGCTCCGGCG
ACATCATCGTCACCAGCTCGCTCGCCGCGCATTACCCGACGCCGTGGGAGCCGGTCTACGCGTCATCGAAATGGGCGATC
GACTGTTTCGTGCAGACCACGCGCCGTCAGGTCTTCAAGCATGGCATCCGCGTCGGTGCGATCTCGCCCGGCCCGGTGGT
CACAGCCCTGATCGCGGACTGGCCGGCCGAGAAGCTGAAGGAGGCGCGCGAGTCCGGCAGCCTGCTGGAGCCCGCGGAGG
TCGCCGACGTCATCCTCTTCATGCTGACCCGCCCGCGCGGCATGACCATCCGGGATGTCGTGATGCTGCCGACGAATTTC
GATCTGTAG

Upstream 100 bases:

>100_bases
TTCAATGGGGTCAGACTGGAACGCGCGGGCGCTACGTTGGGTCCAAACGAGCGGCTGAGCTTGAAATGCGCTAGGCTGCG
CGCGCACAAGGGAGGATGCT

Downstream 100 bases:

>100_bases
CAGACGGGCAAGTTATTGATCAGCGCGGTCGCGGCGACCTCATTTTACCTCGTCCGCGTGTCGGAACAGGCCGGATTGCA
TCGTGAGATGCAATCCGGGT

Product: ribitol 2-dehydrogenase (RDH)

Products: NA

Alternate protein names: RDH [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MGRELEGKVAAVTGAASGIGLASSEAMLAAGARVVMIDRDAAALARLREQHGEAIIPVVIDLLDPTDCATLLPRVLDAAG
RLDIFHANAGSYLGGDLVDARTDAIDRMLHLNINVVMKNVRDVLPHMIARGSGDIIVTSSLAAHYPTPWEPVYASSKWAI
DCFVQTTRRQVFKHGIRVGAISPGPVVTALIADWPAEKLKEARESGSLLEPAEVADVILFMLTRPRGMTIRDVVMLPTNF
DL

Sequences:

>Translated_242_residues
MGRELEGKVAAVTGAASGIGLASSEAMLAAGARVVMIDRDAAALARLREQHGEAIIPVVIDLLDPTDCATLLPRVLDAAG
RLDIFHANAGSYLGGDLVDARTDAIDRMLHLNINVVMKNVRDVLPHMIARGSGDIIVTSSLAAHYPTPWEPVYASSKWAI
DCFVQTTRRQVFKHGIRVGAISPGPVVTALIADWPAEKLKEARESGSLLEPAEVADVILFMLTRPRGMTIRDVVMLPTNF
DL
>Mature_241_residues
GRELEGKVAAVTGAASGIGLASSEAMLAAGARVVMIDRDAAALARLREQHGEAIIPVVIDLLDPTDCATLLPRVLDAAGR
LDIFHANAGSYLGGDLVDARTDAIDRMLHLNINVVMKNVRDVLPHMIARGSGDIIVTSSLAAHYPTPWEPVYASSKWAID
CFVQTTRRQVFKHGIRVGAISPGPVVTALIADWPAEKLKEARESGSLLEPAEVADVILFMLTRPRGMTIRDVVMLPTNFD
L

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=232, Percent_Identity=33.1896551724138, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=31.2820512820513, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI31542939, Length=227, Percent_Identity=30.8370044052863, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=26.9387755102041, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI40254992, Length=222, Percent_Identity=27.9279279279279, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI32483357, Length=229, Percent_Identity=27.5109170305677, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=29.2929292929293, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=32.7485380116959, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI223718074, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI157739938, Length=235, Percent_Identity=23.4042553191489, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031737, Length=229, Percent_Identity=26.6375545851528, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=238, Percent_Identity=31.9327731092437, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=27.5, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787335, Length=225, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1786812, Length=246, Percent_Identity=25.609756097561, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082160, Length=191, Percent_Identity=28.2722513089005, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=23.9316239316239, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786701, Length=190, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789208, Length=201, Percent_Identity=27.8606965174129, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788891, Length=164, Percent_Identity=28.6585365853659, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=243, Percent_Identity=30.0411522633745, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193204405, Length=243, Percent_Identity=30.4526748971193, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=244, Percent_Identity=29.5081967213115, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=250, Percent_Identity=28.4, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=240, Percent_Identity=30.4166666666667, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=244, Percent_Identity=27.4590163934426, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=244, Percent_Identity=28.6885245901639, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562990, Length=241, Percent_Identity=27.3858921161826, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=244, Percent_Identity=27.0491803278689, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=241, Percent_Identity=29.8755186721992, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=248, Percent_Identity=26.6129032258064, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=244, Percent_Identity=29.0983606557377, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=241, Percent_Identity=26.1410788381743, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=242, Percent_Identity=26.4462809917355, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=245, Percent_Identity=25.7142857142857, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=251, Percent_Identity=26.6932270916335, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=247, Percent_Identity=27.5303643724696, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=27.3858921161826, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=193, Percent_Identity=27.4611398963731, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=216, Percent_Identity=26.3888888888889, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=237, Percent_Identity=25.7383966244726, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=202, Percent_Identity=27.2277227722772, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=27.9352226720648, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6322067, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007236, Length=244, Percent_Identity=28.2786885245902, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=28.0612244897959, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364494, Length=249, Percent_Identity=28.9156626506024, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI23397609, Length=236, Percent_Identity=29.2372881355932, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648944, Length=238, Percent_Identity=27.7310924369748, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=220, Percent_Identity=26.8181818181818, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571387, Length=255, Percent_Identity=26.2745098039216, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580925, Length=200, Percent_Identity=26, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641232, Length=247, Percent_Identity=24.6963562753036, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24644339, Length=224, Percent_Identity=24.5535714285714, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007238, Length=184, Percent_Identity=29.8913043478261, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639444, Length=224, Percent_Identity=28.125, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355319, Length=239, Percent_Identity=26.3598326359833, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24663911, Length=245, Percent_Identity=24.4897959183673, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28571526, Length=220, Percent_Identity=24.0909090909091, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356301, Length=228, Percent_Identity=25, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.56 [H]

Molecular weight: Translated: 25965; Mature: 25834

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRELEGKVAAVTGAASGIGLASSEAMLAAGARVVMIDRDAAALARLREQHGEAIIPVVI
CCCCCCCCEEEEECCCCCCCCCCCCHHHHCCCEEEEEECCHHHHHHHHHHHCCEEEEHHH
DLLDPTDCATLLPRVLDAAGRLDIFHANAGSYLGGDLVDARTDAIDRMLHLNINVVMKNV
HHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDVLPHMIARGSGDIIVTSSLAAHYPTPWEPVYASSKWAIDCFVQTTRRQVFKHGIRVGA
HHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEEC
ISPGPVVTALIADWPAEKLKEARESGSLLEPAEVADVILFMLTRPRGMTIRDVVMLPTNF
CCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
DL
CC
>Mature Secondary Structure 
GRELEGKVAAVTGAASGIGLASSEAMLAAGARVVMIDRDAAALARLREQHGEAIIPVVI
CCCCCCCEEEEECCCCCCCCCCCCHHHHCCCEEEEEECCHHHHHHHHHHHCCEEEEHHH
DLLDPTDCATLLPRVLDAAGRLDIFHANAGSYLGGDLVDARTDAIDRMLHLNINVVMKNV
HHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RDVLPHMIARGSGDIIVTSSLAAHYPTPWEPVYASSKWAIDCFVQTTRRQVFKHGIRVGA
HHHHHHHHHCCCCCEEEEECHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCEEEC
ISPGPVVTALIADWPAEKLKEARESGSLLEPAEVADVILFMLTRPRGMTIRDVVMLPTNF
CCCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
DL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3904726; 2933028; 3891331 [H]