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The map label for this gene is atoS [C]

Identifier: 146343422

GI number: 146343422

Start: 6906007

End: 6907611

Strand: Reverse

Name: atoS [C]

Synonym: BRADO6651

Alternate gene names: 146343422

Gene position: 6907611-6906007 (Counterclockwise)

Preceding gene: 146343426

Following gene: 146343421

Centisome position: 92.64

GC content: 66.11

Gene sequence:

>1605_bases
ATGTCAGACCACAAGCCGCAGCGCGATCGCGCGGTCGTCGACAGCGGCGATGCGTCCGACCTTTCGACCGAGCACCACGA
CATCTTCTTCGCGGCCGTCGAAACGACGCGCATGCCGATGATCGTCACTGATCCGCGCCAGAACGACAATCCGATCCTGT
TCGCCAACCGCGCGTTCCTGGAGATGACCGGCTACGGCCTGACGGAGATCGTCGGCTCGAATTGCCGCTTCCTGCAAGGG
CCCGATACGGACCGCGACACCATCGACGCCGTGCGCACCGCGATCGCCAACCGCCAGGACATCGCGGTGGAGGTTCTGAA
CTATCGCAAGAACGGCGCGGCGTTCTGGAACGCGCTGTTCATCAGCCCGGTCTACAACCGCAACGGCGACCTCGTGTACT
TCTTCGGCTCGCAGCTCGACGTCTCGCGCCGGCGCGATGCCGAGAGCGCGCTGGTGCAGTCGCAGAAGATGGAGGCGATC
GGCCAGCTGACCGGCGGCATCGCCCACGACTTCAACAACATCCTGCAGGTGATCATCGGCTACACCGAGACCCTGCAGGG
AGCCGTGAGCGAGCTGGCGCCGCGCCACCGCCGTGCCGTCGACAACATCCGCACGGCGGCCAACCGCGCCGCGACCCTGA
CGCAGCAGCTGCTGTCGTTCGCGCGCAAGCAGCGGCTCGACAGCCGTCCCATCAACCTCAACAACATGATCGAGACGATG
GTGCAGATGGCGCGGCATACGCTCGGCGAGAGCGTGCGCATCGTCGTCAAGGCGCAGCCGGATCTGTGGAACAGCCGCGT
CGACCAGACCCAGGCGGAGGTCGCGCTGCTCAACCTGTTCGTCAATGCGCGCGATGCGATGCCGCATGGCGGCACGCTCA
CCATCCGCACCGAGAACAAGGACATCGCGGACGAGGACATCCTGCAGTTCGGCGTGCCCAAGTCCGGACGCTACGTCGCG
CTCAAGGTGTCCGACGACGGCGTCGGCATTCCGCACCACATTCTGGCGCGCGTCGCCGAGCCGTTCTTCACCACCAAGGA
CGAGGGCAAGGGCACCGGGCTCGGGCTTGCGATGGTCTACGGCTTCACGCGCCAGTCGGGCGGCAGCACCTATATCTACA
GCGAGGTCGGCCTCGGCACCACGGTGCAGCTGTTGTTTCCGGCGACCGAGCAGGCGATCGCCGTGCCGGCCGTGCGGACG
CCGATGGCGATGGACCGCACGGGCAGCGAGCGTATCCTGATCGTCGAGGACCGCACCGATGTCGCCGAGCTCGCGCGCTC
GATCCTGGAGGATTTCGGCTATCGCACCGAGGTCGCGACCAACGCGCATGCGGCGCTGGAGCTTTTGGATTCCGAGATCC
GATTCGATCTCCTGTTCACCGATCTCGTGATGCCCGGCGGCATGAACGGCACGGTGCTGGCGCGCGAAGCGCGCAAGCGC
CAGCCGAAGCTGAAGGTGCTGCTCACGACCGGCTATTCCGATGCGGCGGTCGAGCGGGCCGACGCCAATATCGGCGAGTT
CGAAATCATCAACAAGCCGTACCGCCGCACCGATCTGGTGCGTCGCGTCCGGCAGTTGCTCGACGGCCCGACCGGCGTGA
CCTGA

Upstream 100 bases:

>100_bases
ACCGGATCTCGCCGAGCGGCATATCAGACGGGCGCGTCCCGGCCCACGGATGCAGCAAGGCCATGTTGGCCGTAACCATG
AGAGGCGGAGCAGGACGAGA

Downstream 100 bases:

>100_bases
TGCAGCGCTTGACCCGGCGACTCCTCGCGTCGAAAGTCGCTGTCGAGAGCGGAGAACCCGGCATGCGCCACGTCACAATC
CAGTCACCGGCCGACGCGCG

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MSDHKPQRDRAVVDSGDASDLSTEHHDIFFAAVETTRMPMIVTDPRQNDNPILFANRAFLEMTGYGLTEIVGSNCRFLQG
PDTDRDTIDAVRTAIANRQDIAVEVLNYRKNGAAFWNALFISPVYNRNGDLVYFFGSQLDVSRRRDAESALVQSQKMEAI
GQLTGGIAHDFNNILQVIIGYTETLQGAVSELAPRHRRAVDNIRTAANRAATLTQQLLSFARKQRLDSRPINLNNMIETM
VQMARHTLGESVRIVVKAQPDLWNSRVDQTQAEVALLNLFVNARDAMPHGGTLTIRTENKDIADEDILQFGVPKSGRYVA
LKVSDDGVGIPHHILARVAEPFFTTKDEGKGTGLGLAMVYGFTRQSGGSTYIYSEVGLGTTVQLLFPATEQAIAVPAVRT
PMAMDRTGSERILIVEDRTDVAELARSILEDFGYRTEVATNAHAALELLDSEIRFDLLFTDLVMPGGMNGTVLAREARKR
QPKLKVLLTTGYSDAAVERADANIGEFEIINKPYRRTDLVRRVRQLLDGPTGVT

Sequences:

>Translated_534_residues
MSDHKPQRDRAVVDSGDASDLSTEHHDIFFAAVETTRMPMIVTDPRQNDNPILFANRAFLEMTGYGLTEIVGSNCRFLQG
PDTDRDTIDAVRTAIANRQDIAVEVLNYRKNGAAFWNALFISPVYNRNGDLVYFFGSQLDVSRRRDAESALVQSQKMEAI
GQLTGGIAHDFNNILQVIIGYTETLQGAVSELAPRHRRAVDNIRTAANRAATLTQQLLSFARKQRLDSRPINLNNMIETM
VQMARHTLGESVRIVVKAQPDLWNSRVDQTQAEVALLNLFVNARDAMPHGGTLTIRTENKDIADEDILQFGVPKSGRYVA
LKVSDDGVGIPHHILARVAEPFFTTKDEGKGTGLGLAMVYGFTRQSGGSTYIYSEVGLGTTVQLLFPATEQAIAVPAVRT
PMAMDRTGSERILIVEDRTDVAELARSILEDFGYRTEVATNAHAALELLDSEIRFDLLFTDLVMPGGMNGTVLAREARKR
QPKLKVLLTTGYSDAAVERADANIGEFEIINKPYRRTDLVRRVRQLLDGPTGVT
>Mature_533_residues
SDHKPQRDRAVVDSGDASDLSTEHHDIFFAAVETTRMPMIVTDPRQNDNPILFANRAFLEMTGYGLTEIVGSNCRFLQGP
DTDRDTIDAVRTAIANRQDIAVEVLNYRKNGAAFWNALFISPVYNRNGDLVYFFGSQLDVSRRRDAESALVQSQKMEAIG
QLTGGIAHDFNNILQVIIGYTETLQGAVSELAPRHRRAVDNIRTAANRAATLTQQLLSFARKQRLDSRPINLNNMIETMV
QMARHTLGESVRIVVKAQPDLWNSRVDQTQAEVALLNLFVNARDAMPHGGTLTIRTENKDIADEDILQFGVPKSGRYVAL
KVSDDGVGIPHHILARVAEPFFTTKDEGKGTGLGLAMVYGFTRQSGGSTYIYSEVGLGTTVQLLFPATEQAIAVPAVRTP
MAMDRTGSERILIVEDRTDVAELARSILEDFGYRTEVATNAHAALELLDSEIRFDLLFTDLVMPGGMNGTVLAREARKRQ
PKLKVLLTTGYSDAAVERADANIGEFEIINKPYRRTDLVRRVRQLLDGPTGVT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI6912446, Length=95, Percent_Identity=36.8421052631579, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI38569493, Length=98, Percent_Identity=30.6122448979592, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=272, Percent_Identity=25.3676470588235, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI48994928, Length=504, Percent_Identity=24.0079365079365, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=260, Percent_Identity=26.1538461538462, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136946, Length=115, Percent_Identity=31.304347826087, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59092; Mature: 58961

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDHKPQRDRAVVDSGDASDLSTEHHDIFFAAVETTRMPMIVTDPRQNDNPILFANRAFL
CCCCCCCCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCEEEECCEEE
EMTGYGLTEIVGSNCRFLQGPDTDRDTIDAVRTAIANRQDIAVEVLNYRKNGAAFWNALF
EECCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHEEHHEE
ISPVYNRNGDLVYFFGSQLDVSRRRDAESALVQSQKMEAIGQLTGGIAHDFNNILQVIIG
EEEEECCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
YTETLQGAVSELAPRHRRAVDNIRTAANRAATLTQQLLSFARKQRLDSRPINLNNMIETM
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VQMARHTLGESVRIVVKAQPDLWNSRVDQTQAEVALLNLFVNARDAMPHGGTLTIRTENK
HHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
DIADEDILQFGVPKSGRYVALKVSDDGVGIPHHILARVAEPFFTTKDEGKGTGLGLAMVY
CCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEHHHHE
GFTRQSGGSTYIYSEVGLGTTVQLLFPATEQAIAVPAVRTPMAMDRTGSERILIVEDRTD
EHHCCCCCCEEEEEECCCCCEEEEEECCCCCCEECCCCCCCCEECCCCCCEEEEEECCCC
VAELARSILEDFGYRTEVATNAHAALELLDSEIRFDLLFTDLVMPGGMNGTVLAREARKR
HHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHEEEEEHHHCCCCCCCCEEECHHHHC
QPKLKVLLTTGYSDAAVERADANIGEFEIINKPYRRTDLVRRVRQLLDGPTGVT
CCCEEEEEEECCCHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDHKPQRDRAVVDSGDASDLSTEHHDIFFAAVETTRMPMIVTDPRQNDNPILFANRAFL
CCCCCCCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCEEEECCEEE
EMTGYGLTEIVGSNCRFLQGPDTDRDTIDAVRTAIANRQDIAVEVLNYRKNGAAFWNALF
EECCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHEEHHEE
ISPVYNRNGDLVYFFGSQLDVSRRRDAESALVQSQKMEAIGQLTGGIAHDFNNILQVIIG
EEEEECCCCCEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
YTETLQGAVSELAPRHRRAVDNIRTAANRAATLTQQLLSFARKQRLDSRPINLNNMIETM
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
VQMARHTLGESVRIVVKAQPDLWNSRVDQTQAEVALLNLFVNARDAMPHGGTLTIRTENK
HHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
DIADEDILQFGVPKSGRYVALKVSDDGVGIPHHILARVAEPFFTTKDEGKGTGLGLAMVY
CCCHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEHHHHE
GFTRQSGGSTYIYSEVGLGTTVQLLFPATEQAIAVPAVRTPMAMDRTGSERILIVEDRTD
EHHCCCCCCEEEEEECCCCCEEEEEECCCCCCEECCCCCCCCEECCCCCCEEEEEECCCC
VAELARSILEDFGYRTEVATNAHAALELLDSEIRFDLLFTDLVMPGGMNGTVLAREARKR
HHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHEEEEEHHHCCCCCCCCEEECHHHHC
QPKLKVLLTTGYSDAAVERADANIGEFEIINKPYRRTDLVRRVRQLLDGPTGVT
CCCEEEEEEECCCHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA