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The map label for this gene is thrB [H]

Identifier: 146343360

GI number: 146343360

Start: 6837112

End: 6838083

Strand: Reverse

Name: thrB [H]

Synonym: BRADO6587

Alternate gene names: 146343360

Gene position: 6838083-6837112 (Counterclockwise)

Preceding gene: 146343361

Following gene: 146343359

Centisome position: 91.71

GC content: 66.77

Gene sequence:

>972_bases
ATGGCGGTCTATACCGACGTCGCCGCCGACGAGCTTGCGGACTTCCTCAAGACCTACGACATCGGCGAGCTGCTCTCCTA
CAAGGGCATCGCCGAGGGCGTCGAGAACTCCAACTTCCTGCTGCACACCACGAAGGGCTCCTACATCCTCACGCTCTATG
AGAAGCGCGTGGCGGTGGACGATCTGCCGTATTTTCTGGGCCTGATGGCCCATCTCGCCGAGCGCGGCGTCAACTGCCCG
CAGCCGGCGCGCAACCGCGACGGCGCGGTGTATTCCAGCCTGGCCGGCCGGCCGGCGGCGATCATCAACTTTCTCGAAGG
GATGTGGCCGCGCAAGCCGGCCGTCGTGCATTGCGCAGGCGTTGGCGAGGCGCTGGCGCGGATGCATTTGGCTGGGCGCG
ACTTCCCGCTGGTGCGCAAGAACCCGCTGTCGGTGTCCGGCTGGCAATCGCTGTTCGCCCAGGCGGCCGATCGCGCCGAC
ACGGTGCAGGCCGGCCTGTCCGCGCTGCTCTCGACCGAGTTGGACTACCTTGCGCGCGCCTGGCCGACAGATCTGCCGGA
AGGCGTCATTCACGCCGACCTGTTTCCGGACAACGTCTTCTTCCTCGGCGACCATCTGTCCGGACTGATCGACTTCCCGT
TCTCCTGCAACGACATCCTCGCCTATGACGTGGCGATCTGCCTGAACGCCTGGTGCTTCGAGGCCGACCATTCGCTCAAC
GTCACCAAGGCGCGCGCCTTCTTCAATGCGTATGGCCGCGCGCGGCCGCTGTCGGACGCGGAGCTGGAGGCGCTGCCGCT
GCTCGCGCGCGGCGCCGCGATCCGCTTCCTGCTGACGCGGCTGGTCGACTGGCTCAACGTGCCCGCGGGCGCGCTGGTGA
AGCCGAAGGATCCGCTCGAATATGTCCGCAAGCTGCGCTTCCATCAGGCGGTGACCAGCGCGCGCGACTACGGCATCGGA
GCATCCGCATGA

Upstream 100 bases:

>100_bases
CGACGCCCGCATGCGCGATGAAGGCGCAACGGGCCTGTCCGGTGACGAAGTTCGCAGCGGAGAGGCGGGGGCAGGCGAAC
TTCGATAACCGGGACATCGC

Downstream 100 bases:

>100_bases
GCGAGCTTCCGGTCGTCAGCATCTTCACCGACGGCGCCTGCTCCGGAAATCCCGGCCCTGGCGGCTGGGGCGCGATCCTG
CGCTTCGGCGACAAGGAGAA

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAVYTDVAADELADFLKTYDIGELLSYKGIAEGVENSNFLLHTTKGSYILTLYEKRVAVDDLPYFLGLMAHLAERGVNCP
QPARNRDGAVYSSLAGRPAAIINFLEGMWPRKPAVVHCAGVGEALARMHLAGRDFPLVRKNPLSVSGWQSLFAQAADRAD
TVQAGLSALLSTELDYLARAWPTDLPEGVIHADLFPDNVFFLGDHLSGLIDFPFSCNDILAYDVAICLNAWCFEADHSLN
VTKARAFFNAYGRARPLSDAELEALPLLARGAAIRFLLTRLVDWLNVPAGALVKPKDPLEYVRKLRFHQAVTSARDYGIG
ASA

Sequences:

>Translated_323_residues
MAVYTDVAADELADFLKTYDIGELLSYKGIAEGVENSNFLLHTTKGSYILTLYEKRVAVDDLPYFLGLMAHLAERGVNCP
QPARNRDGAVYSSLAGRPAAIINFLEGMWPRKPAVVHCAGVGEALARMHLAGRDFPLVRKNPLSVSGWQSLFAQAADRAD
TVQAGLSALLSTELDYLARAWPTDLPEGVIHADLFPDNVFFLGDHLSGLIDFPFSCNDILAYDVAICLNAWCFEADHSLN
VTKARAFFNAYGRARPLSDAELEALPLLARGAAIRFLLTRLVDWLNVPAGALVKPKDPLEYVRKLRFHQAVTSARDYGIG
ASA
>Mature_322_residues
AVYTDVAADELADFLKTYDIGELLSYKGIAEGVENSNFLLHTTKGSYILTLYEKRVAVDDLPYFLGLMAHLAERGVNCPQ
PARNRDGAVYSSLAGRPAAIINFLEGMWPRKPAVVHCAGVGEALARMHLAGRDFPLVRKNPLSVSGWQSLFAQAADRADT
VQAGLSALLSTELDYLARAWPTDLPEGVIHADLFPDNVFFLGDHLSGLIDFPFSCNDILAYDVAICLNAWCFEADHSLNV
TKARAFFNAYGRARPLSDAELEALPLLARGAAIRFLLTRLVDWLNVPAGALVKPKDPLEYVRKLRFHQAVTSARDYGIGA
SA

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 35356; Mature: 35225

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDVAADELADFLKTYDIGELLSYKGIAEGVENSNFLLHTTKGSYILTLYEKRVAVD
CCEECHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHHHH
DLPYFLGLMAHLAERGVNCPQPARNRDGAVYSSLAGRPAAIINFLEGMWPRKPAVVHCAG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCEEEECC
VGEALARMHLAGRDFPLVRKNPLSVSGWQSLFAQAADRADTVQAGLSALLSTELDYLARA
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPTDLPEGVIHADLFPDNVFFLGDHLSGLIDFPFSCNDILAYDVAICLNAWCFEADHSLN
CCCCCCCCCEEECCCCCCEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
VTKARAFFNAYGRARPLSDAELEALPLLARGAAIRFLLTRLVDWLNVPAGALVKPKDPLE
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YVRKLRFHQAVTSARDYGIGASA
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AVYTDVAADELADFLKTYDIGELLSYKGIAEGVENSNFLLHTTKGSYILTLYEKRVAVD
CEECHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEHHHHHHH
DLPYFLGLMAHLAERGVNCPQPARNRDGAVYSSLAGRPAAIINFLEGMWPRKPAVVHCAG
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCEEEECC
VGEALARMHLAGRDFPLVRKNPLSVSGWQSLFAQAADRADTVQAGLSALLSTELDYLARA
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WPTDLPEGVIHADLFPDNVFFLGDHLSGLIDFPFSCNDILAYDVAICLNAWCFEADHSLN
CCCCCCCCCEEECCCCCCEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
VTKARAFFNAYGRARPLSDAELEALPLLARGAAIRFLLTRLVDWLNVPAGALVKPKDPLE
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
YVRKLRFHQAVTSARDYGIGASA
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA