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The map label for this gene is mhpA [H]

Identifier: 146342865

GI number: 146342865

Start: 6269831

End: 6271354

Strand: Direct

Name: mhpA [H]

Synonym: BRADO6045

Alternate gene names: 146342865

Gene position: 6269831-6271354 (Clockwise)

Preceding gene: 146342864

Following gene: 146342866

Centisome position: 84.08

GC content: 67.98

Gene sequence:

>1524_bases
ATGAGCAACACGGCCGTACACTCTCCAAACTTCGACGTCGTCATCGTTGGTCGCGGGCCGGTCGGCTCGACGCTCGGCAA
TCTGCTCGGCCTGTGCGGCCTCCGCACCCTGATCCTGGAGCGCGAGGCCAAGACCTATCACTTGCCGCGCGCGGTGCATT
TCGACGACGAATGCATGCGCGTGTTCCAGACCATCGGCCTCGCGGACGCCATCCTGCCCCATGTCACCTTGAGTCCCGGC
ATGCGCTTCGTCGATGCGGACGGCCGATTGCTACTCGACTGGCCTCGCCCCAGCGAACCGACCGCGATGGGCTGGAATCT
GAGCTACCGCTTTCACCAGCCCGATCTCGAAGCCGTGCTCAATGACGGCCTGGAGCGGTGGGCGCATGTCGACCTTCGCA
CGCGCTGCGAAGTCTTTGCGCTCGAGCAGGATCACAGCGGCGCGCGCGTTCGTTACGAGGAGTTGGACACCGGCCGGCTC
GTCGACATCTCCTGCGCCTATGTGGTCGGCTGCGATGGTGCGCGGTCGCTGGTGCGCCGCTTCATCGGCTCGGCGCTGGA
CGATCTCGGCTTTCACGAGCGCTGGCTGGTCTGCGACGTGCTGCTGCGCGAGGCGCGGCCGGACCTCGGCGATTTCAGCG
TCCAGCACTGCAACCCGCAGCGTCCGGCGACCTACATTCGCGGCACCGGCAGCCGCCGCCGCTGGGAGATCACGGTTCAC
CCCCACGAAGACGCCGCCGAGATTACCCGGCCTGCGCGCGTCTGGGAGCTGCTTTCGCCCTGGCTGCGGCCCGCCGAGGC
GGAGATCGAACGTGCCGCCGTCTACACCTTCCACTCCGCGGTGGCCCAGCGATGGCGCAACGGACGCTTCCTGCTCGCAG
GCGATTCCGCGCATCAGACCCCACCGTTCCTTGGCCAGGGCATGTGCGCCGGCATTCGCGATGTGGCCAACCTCGCCTGG
AAACTGGCGCGCGTGATCGCCGGCAAGGCAACGCCTGATCTTCTCGACACCTATCAAAGTGAACGCGCGCCGCATGTGCG
CGAATTCATCGAACTCGCGATCCGGCTAGGTGGTCTCATCAACACCAAGGCGGTCGAGGCGGCGCTCGCGACCGGCACGG
CGCAGGGCGACGGCCAGCTCAAGCTCGACGTGCAGAAGCCGCTGCTAGGACCGGGCCTGGCTTGCGGCGATCGCAGCCTG
ACGGGACGACTCGCGCCGCAATTCCGCGGCCGCGACCACAGCCGCAGCGACGATCGCGTCGGCTATCGCTTCGCGCTGCT
GTGCCGGTCGGGCCTGGAGGCCGCGGTTATCGAGCAGCATCATGCCGATCTGTCGGCCGCTGACGTCGCGATCGTTTGCG
GCCAGGAGGCCGGTGGCCTCGATGCGTGGCTCGATCAGCACGGCTCCGATGCCGTTTTGATGCGTCCGGACCGCTACATC
CTCGGGGCCGTCCGCACCGGCGAGGATGCCGCGTCGCTGCTGTCCGGCGTCGCCCGACTCGCACCGCTGCCGAGCGCCGC
CTGA

Upstream 100 bases:

>100_bases
CGCCGCGGCCGCCATTCCAGTCGAACGCTAGGCGTCCGCTGGGCGGACAGTTCGTGACCGCGCCTTGAAGCTGCGAGGCG
GTTGCGGATCAGATGCGGCT

Downstream 100 bases:

>100_bases
TCTTTTCCGTCTTTCCTGAAAGGGCTCACGTATGAAGCTGGTTTCCTTTGTCATCGACGGGCGTTCCGGTTACGGCGCGG
TGAAGGGCGATGGTGTCGTC

Product: 3-(3-hydroxyphenyl)propionate hydroxylase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase; Flavin-type monooxygenase [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSNTAVHSPNFDVVIVGRGPVGSTLGNLLGLCGLRTLILEREAKTYHLPRAVHFDDECMRVFQTIGLADAILPHVTLSPG
MRFVDADGRLLLDWPRPSEPTAMGWNLSYRFHQPDLEAVLNDGLERWAHVDLRTRCEVFALEQDHSGARVRYEELDTGRL
VDISCAYVVGCDGARSLVRRFIGSALDDLGFHERWLVCDVLLREARPDLGDFSVQHCNPQRPATYIRGTGSRRRWEITVH
PHEDAAEITRPARVWELLSPWLRPAEAEIERAAVYTFHSAVAQRWRNGRFLLAGDSAHQTPPFLGQGMCAGIRDVANLAW
KLARVIAGKATPDLLDTYQSERAPHVREFIELAIRLGGLINTKAVEAALATGTAQGDGQLKLDVQKPLLGPGLACGDRSL
TGRLAPQFRGRDHSRSDDRVGYRFALLCRSGLEAAVIEQHHADLSAADVAIVCGQEAGGLDAWLDQHGSDAVLMRPDRYI
LGAVRTGEDAASLLSGVARLAPLPSAA

Sequences:

>Translated_507_residues
MSNTAVHSPNFDVVIVGRGPVGSTLGNLLGLCGLRTLILEREAKTYHLPRAVHFDDECMRVFQTIGLADAILPHVTLSPG
MRFVDADGRLLLDWPRPSEPTAMGWNLSYRFHQPDLEAVLNDGLERWAHVDLRTRCEVFALEQDHSGARVRYEELDTGRL
VDISCAYVVGCDGARSLVRRFIGSALDDLGFHERWLVCDVLLREARPDLGDFSVQHCNPQRPATYIRGTGSRRRWEITVH
PHEDAAEITRPARVWELLSPWLRPAEAEIERAAVYTFHSAVAQRWRNGRFLLAGDSAHQTPPFLGQGMCAGIRDVANLAW
KLARVIAGKATPDLLDTYQSERAPHVREFIELAIRLGGLINTKAVEAALATGTAQGDGQLKLDVQKPLLGPGLACGDRSL
TGRLAPQFRGRDHSRSDDRVGYRFALLCRSGLEAAVIEQHHADLSAADVAIVCGQEAGGLDAWLDQHGSDAVLMRPDRYI
LGAVRTGEDAASLLSGVARLAPLPSAA
>Mature_506_residues
SNTAVHSPNFDVVIVGRGPVGSTLGNLLGLCGLRTLILEREAKTYHLPRAVHFDDECMRVFQTIGLADAILPHVTLSPGM
RFVDADGRLLLDWPRPSEPTAMGWNLSYRFHQPDLEAVLNDGLERWAHVDLRTRCEVFALEQDHSGARVRYEELDTGRLV
DISCAYVVGCDGARSLVRRFIGSALDDLGFHERWLVCDVLLREARPDLGDFSVQHCNPQRPATYIRGTGSRRRWEITVHP
HEDAAEITRPARVWELLSPWLRPAEAEIERAAVYTFHSAVAQRWRNGRFLLAGDSAHQTPPFLGQGMCAGIRDVANLAWK
LARVIAGKATPDLLDTYQSERAPHVREFIELAIRLGGLINTKAVEAALATGTAQGDGQLKLDVQKPLLGPGLACGDRSLT
GRLAPQFRGRDHSRSDDRVGYRFALLCRSGLEAAVIEQHHADLSAADVAIVCGQEAGGLDAWLDQHGSDAVLMRPDRYIL
GAVRTGEDAASLLSGVARLAPLPSAA

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=520, Percent_Identity=31.5384615384615, Blast_Score=210, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 55656; Mature: 55525

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTAVHSPNFDVVIVGRGPVGSTLGNLLGLCGLRTLILEREAKTYHLPRAVHFDDECMR
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHEECCEEECCCHHHHH
VFQTIGLADAILPHVTLSPGMRFVDADGRLLLDWPRPSEPTAMGWNLSYRFHQPDLEAVL
HHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCEECCEEEEEECCCHHHHHH
NDGLERWAHVDLRTRCEVFALEQDHSGARVRYEELDTGRLVDISCAYVVGCDGARSLVRR
HHHHHHHHCCCHHHCEEEEEEECCCCCCEEEEEECCCCCEEEEEEEEEEECCHHHHHHHH
FIGSALDDLGFHERWLVCDVLLREARPDLGDFSVQHCNPQRPATYIRGTGSRRRWEITVH
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEC
PHEDAAEITRPARVWELLSPWLRPAEAEIERAAVYTFHSAVAQRWRNGRFLLAGDSAHQT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
PPFLGQGMCAGIRDVANLAWKLARVIAGKATPDLLDTYQSERAPHVREFIELAIRLGGLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
NTKAVEAALATGTAQGDGQLKLDVQKPLLGPGLACGDRSLTGRLAPQFRGRDHSRSDDRV
CHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
GYRFALLCRSGLEAAVIEQHHADLSAADVAIVCGQEAGGLDAWLDQHGSDAVLMRPDRYI
CHHHEEHHHCCCCHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHCCCCCEEEECCCCEE
LGAVRTGEDAASLLSGVARLAPLPSAA
EEEEECCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SNTAVHSPNFDVVIVGRGPVGSTLGNLLGLCGLRTLILEREAKTYHLPRAVHFDDECMR
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHEECCEEECCCHHHHH
VFQTIGLADAILPHVTLSPGMRFVDADGRLLLDWPRPSEPTAMGWNLSYRFHQPDLEAVL
HHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCEECCEEEEEECCCHHHHHH
NDGLERWAHVDLRTRCEVFALEQDHSGARVRYEELDTGRLVDISCAYVVGCDGARSLVRR
HHHHHHHHCCCHHHCEEEEEEECCCCCCEEEEEECCCCCEEEEEEEEEEECCHHHHHHHH
FIGSALDDLGFHERWLVCDVLLREARPDLGDFSVQHCNPQRPATYIRGTGSRRRWEITVH
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEC
PHEDAAEITRPARVWELLSPWLRPAEAEIERAAVYTFHSAVAQRWRNGRFLLAGDSAHQT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
PPFLGQGMCAGIRDVANLAWKLARVIAGKATPDLLDTYQSERAPHVREFIELAIRLGGLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
NTKAVEAALATGTAQGDGQLKLDVQKPLLGPGLACGDRSLTGRLAPQFRGRDHSRSDDRV
CHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCC
GYRFALLCRSGLEAAVIEQHHADLSAADVAIVCGQEAGGLDAWLDQHGSDAVLMRPDRYI
CHHHEEHHHCCCCHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHCCCCCEEEECCCCEE
LGAVRTGEDAASLLSGVARLAPLPSAA
EEEEECCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA