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The map label for this gene is ycgM [C]

Identifier: 146342866

GI number: 146342866

Start: 6271386

End: 6272237

Strand: Direct

Name: ycgM [C]

Synonym: BRADO6046

Alternate gene names: 146342866

Gene position: 6271386-6272237 (Clockwise)

Preceding gene: 146342865

Following gene: 146342867

Centisome position: 84.11

GC content: 66.43

Gene sequence:

>852_bases
ATGAAGCTGGTTTCCTTTGTCATCGACGGGCGTTCCGGTTACGGCGCGGTGAAGGGCGATGGTGTCGTCGACCTCGGCCG
GCGCCTGCCGTCGAAGAGCCTGCGCGCGCTGCTCGAGGCGGACGCGCTCGGCGCCGCTGCCGCGCTGCTCGCCTCCGAGC
CGGTCGACTATCCCCTGAGCGCGCTTGCCTTAGCGCCCGTCATTCCCGATCCCGGCAAGATCATCTGCGTCGGCCTGAAC
TATCGCGACCACGTCGCCGAGACCGGCCGGACCGTGACCGAGAAGCCCGCTTTGTTCGCGCGTTTTCCGACGAGCCAAGT
GGGACATCTGCAGCCGATCGTTCGCCCTGATGTCTCCGATCATTTCGACTACGAAGGCGAGCTTGCGCTCGTGATCGGCA
AGGCAGGCCGGCACGTCCGGCGCGAGGACGCGCTCACGCATGTCGCCGGCTATTCCTGCTACAATGAAGGCAGCATCCGC
GACTGGCAGCGCCATACGTCGCAATTCCTGTCGGGCAAGACCTTCGACAAGTCCGGCGCCTTCGGCCCCTGGCTGGTCAC
CGCCGACGAGATCCCCGACCCGTCCAGGCTGACGCTGCAGACCCGCCTCAATGGCGAGACCGTGCAGCGGACCACGACGG
ATCGGCTGATCACCGACGTGCCCGACCTGATCGTCTATTGCTCGACCATCATGACTCTGCTGCCGGGCGATGTGATCGTC
ACCGGCACGCCGGGAGGCGTCGGCTTCAAGCGCACGCCGCCGTTGTTCATGCAGCCGGGCGATACGGTCGAGGTCGAGAT
CTCCGGCATCGGCGTGCTGCGCAATCCCGTGACCGCCGAAACGGCCGCCTGA

Upstream 100 bases:

>100_bases
ACCGGCGAGGATGCCGCGTCGCTGCTGTCCGGCGTCGCCCGACTCGCACCGCTGCCGAGCGCCGCCTGATCTTTTCCGTC
TTTCCTGAAAGGGCTCACGT

Downstream 100 bases:

>100_bases
CGTCTTCGCCTCGCGGACAACCGCTGGGCGCTCCAATCAAACACGACATAACAAACAAGATCGTTGAACCCGGGGAGGAT
CATCATGTCGCGCCGTCTCA

Product: bifunctional enzyme with isomerase/decarboxylase activity

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKLVSFVIDGRSGYGAVKGDGVVDLGRRLPSKSLRALLEADALGAAAALLASEPVDYPLSALALAPVIPDPGKIICVGLN
YRDHVAETGRTVTEKPALFARFPTSQVGHLQPIVRPDVSDHFDYEGELALVIGKAGRHVRREDALTHVAGYSCYNEGSIR
DWQRHTSQFLSGKTFDKSGAFGPWLVTADEIPDPSRLTLQTRLNGETVQRTTTDRLITDVPDLIVYCSTIMTLLPGDVIV
TGTPGGVGFKRTPPLFMQPGDTVEVEISGIGVLRNPVTAETAA

Sequences:

>Translated_283_residues
MKLVSFVIDGRSGYGAVKGDGVVDLGRRLPSKSLRALLEADALGAAAALLASEPVDYPLSALALAPVIPDPGKIICVGLN
YRDHVAETGRTVTEKPALFARFPTSQVGHLQPIVRPDVSDHFDYEGELALVIGKAGRHVRREDALTHVAGYSCYNEGSIR
DWQRHTSQFLSGKTFDKSGAFGPWLVTADEIPDPSRLTLQTRLNGETVQRTTTDRLITDVPDLIVYCSTIMTLLPGDVIV
TGTPGGVGFKRTPPLFMQPGDTVEVEISGIGVLRNPVTAETAA
>Mature_283_residues
MKLVSFVIDGRSGYGAVKGDGVVDLGRRLPSKSLRALLEADALGAAAALLASEPVDYPLSALALAPVIPDPGKIICVGLN
YRDHVAETGRTVTEKPALFARFPTSQVGHLQPIVRPDVSDHFDYEGELALVIGKAGRHVRREDALTHVAGYSCYNEGSIR
DWQRHTSQFLSGKTFDKSGAFGPWLVTADEIPDPSRLTLQTRLNGETVQRTTTDRLITDVPDLIVYCSTIMTLLPGDVIV
TGTPGGVGFKRTPPLFMQPGDTVEVEISGIGVLRNPVTAETAA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=287, Percent_Identity=39.7212543554007, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI156231349, Length=287, Percent_Identity=40.0696864111498, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI66348062, Length=202, Percent_Identity=34.6534653465347, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI215422413, Length=202, Percent_Identity=34.6534653465347, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=35.1485148514851, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1787428, Length=219, Percent_Identity=34.2465753424658, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=36.8715083798883, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28572127, Length=220, Percent_Identity=44.5454545454545, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24663695, Length=217, Percent_Identity=36.8663594470046, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571789, Length=216, Percent_Identity=34.7222222222222, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 30345; Mature: 30345

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVSFVIDGRSGYGAVKGDGVVDLGRRLPSKSLRALLEADALGAAAALLASEPVDYPLS
CCEEEEEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ALALAPVIPDPGKIICVGLNYRDHVAETGRTVTEKPALFARFPTSQVGHLQPIVRPDVSD
HHHEECCCCCCCCEEEEECCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
HFDYEGELALVIGKAGRHVRREDALTHVAGYSCYNEGSIRDWQRHTSQFLSGKTFDKSGA
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
FGPWLVTADEIPDPSRLTLQTRLNGETVQRTTTDRLITDVPDLIVYCSTIMTLLPGDVIV
CCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TGTPGGVGFKRTPPLFMQPGDTVEVEISGIGVLRNPVTAETAA
ECCCCCCCCCCCCCCEECCCCEEEEEEECEEEECCCCCCCCCC
>Mature Secondary Structure
MKLVSFVIDGRSGYGAVKGDGVVDLGRRLPSKSLRALLEADALGAAAALLASEPVDYPLS
CCEEEEEEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
ALALAPVIPDPGKIICVGLNYRDHVAETGRTVTEKPALFARFPTSQVGHLQPIVRPDVSD
HHHEECCCCCCCCEEEEECCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
HFDYEGELALVIGKAGRHVRREDALTHVAGYSCYNEGSIRDWQRHTSQFLSGKTFDKSGA
CCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
FGPWLVTADEIPDPSRLTLQTRLNGETVQRTTTDRLITDVPDLIVYCSTIMTLLPGDVIV
CCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TGTPGGVGFKRTPPLFMQPGDTVEVEISGIGVLRNPVTAETAA
ECCCCCCCCCCCCCCEECCCCEEEEEEECEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]