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The map label for this gene is aatA [H]

Identifier: 146342796

GI number: 146342796

Start: 6204703

End: 6205908

Strand: Reverse

Name: aatA [H]

Synonym: BRADO5973

Alternate gene names: 146342796

Gene position: 6205908-6204703 (Counterclockwise)

Preceding gene: 146342802

Following gene: 146342795

Centisome position: 83.23

GC content: 64.26

Gene sequence:

>1206_bases
ATGATGTCCTTTCTCGCCGCTGCGCTCGACCGTGTGAAGCCGTCCGCGACCATCGCGGTCACGGACAAAGCGCGCGTCCT
CAAAGCGGCGGGCCGCAACGTCATCGGGCTGGGTGCCGGCGAGCCGGATTTCGATACGCCCGACAACATCAAGCAGGCCG
CGATCAAGGCGATCCAGGACGGCAAGACCAAGTACACCGCGGTGGACGGCATTCCCGAGCTGAAGGACGCCATCATCGGC
AAGTTCCAGCGCGAGAACGGCCTGACCTACAAGCCGAACCAGGTGATCGTCGGCGTCGGCGGCAAGCAGGTGCTCTACAA
TGCGCTGATGGCGACCATCAATCCCGGCGATGAGGTGATCATCCCGGCACCTTACTGGGTCAGCTATCCGGAGATGGTGG
CGCTCGCCGGCGGCGAGCCGGTACCGGTGGTCTGCACGTCGGCGCACGGCTTCAAGCTGCAGCCGGAGGCGCTGGAGAAG
GCGATCACGCCGAAGACCAAATGGCTGATCCTGTGCTCGCCATCGAACCCGACCGGCGCGGCCTACACCAAGGCCGAGCT
GAAGGCGCTCACCGACGTGCTGGTCAAGCATCCGCATGTCTGGATCATGACCGACGACATGTACGAGCACCTGGTCTATG
ACGACTTCGTCTTCACGACGCCGGCGCAGATCGAGCCTTCGCTGTTCGACCGCACGCTGACCGTGAACGGCGTCTCCAAG
GCCTATTGCATGACCGGCTGGCGCATCGGCTATGCCGGCGGCCCCGCGCAGCTGATCAAGGCGATGGCGACGATCCAGTC
GCAGTCGACCTCGAACCCGTGCTCGATCGCGCAATGGGCGGCGGTGGAGGCCTTGAACGGTCCGCAGCACTTCATTCCTG
AGAACAACAAGGTGTTCAAGGAGCGCCGCGACCTCGTGGTGTCGATGCTCAACCAGGCGAGCGGCATCGAGTGCCCGCGT
CCCGAGGGCGCGTTCTACGTCTATCCGTCCTGCGCCGGCACGATCGGCAAGACCACGCCGTCGGGCAAGGTAATCGATAA
CGACCAGACCTTCGTCACCGAGCTGTTGGAGACCGAGGGCGTCGCCGTCGTGCAAGGCTCGGCTTTCGGCCTCGGCCCGG
CGTTCCGCATCTCCTACGCCACCAAGACCTCGGATCTCGAGGACGCCTGCAAGCGTATCCAGCGCTTCTGCGGCAATCTG
AGGTAA

Upstream 100 bases:

>100_bases
AAAGCAGACGTTTCCCTGACATGACTGGTCGTGGCCCGAAAAGGGTGATCCACGACGCGTGATCCAAGACACCTTATCCA
AGACGCCTGCATAGGAGCTG

Downstream 100 bases:

>100_bases
TCGGGCAACAGCTGCCTCGAAACACCAGAAGCCCATATCCAGGCCGAAAGGCGCCATGTTTTGAACATGGCGCCTTTCTT
CTGTCCGGAGTGAAGTTGGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MMSFLAAALDRVKPSATIAVTDKARVLKAAGRNVIGLGAGEPDFDTPDNIKQAAIKAIQDGKTKYTAVDGIPELKDAIIG
KFQRENGLTYKPNQVIVGVGGKQVLYNALMATINPGDEVIIPAPYWVSYPEMVALAGGEPVPVVCTSAHGFKLQPEALEK
AITPKTKWLILCSPSNPTGAAYTKAELKALTDVLVKHPHVWIMTDDMYEHLVYDDFVFTTPAQIEPSLFDRTLTVNGVSK
AYCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPCSIAQWAAVEALNGPQHFIPENNKVFKERRDLVVSMLNQASGIECPR
PEGAFYVYPSCAGTIGKTTPSGKVIDNDQTFVTELLETEGVAVVQGSAFGLGPAFRISYATKTSDLEDACKRIQRFCGNL
R

Sequences:

>Translated_401_residues
MMSFLAAALDRVKPSATIAVTDKARVLKAAGRNVIGLGAGEPDFDTPDNIKQAAIKAIQDGKTKYTAVDGIPELKDAIIG
KFQRENGLTYKPNQVIVGVGGKQVLYNALMATINPGDEVIIPAPYWVSYPEMVALAGGEPVPVVCTSAHGFKLQPEALEK
AITPKTKWLILCSPSNPTGAAYTKAELKALTDVLVKHPHVWIMTDDMYEHLVYDDFVFTTPAQIEPSLFDRTLTVNGVSK
AYCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPCSIAQWAAVEALNGPQHFIPENNKVFKERRDLVVSMLNQASGIECPR
PEGAFYVYPSCAGTIGKTTPSGKVIDNDQTFVTELLETEGVAVVQGSAFGLGPAFRISYATKTSDLEDACKRIQRFCGNL
R
>Mature_401_residues
MMSFLAAALDRVKPSATIAVTDKARVLKAAGRNVIGLGAGEPDFDTPDNIKQAAIKAIQDGKTKYTAVDGIPELKDAIIG
KFQRENGLTYKPNQVIVGVGGKQVLYNALMATINPGDEVIIPAPYWVSYPEMVALAGGEPVPVVCTSAHGFKLQPEALEK
AITPKTKWLILCSPSNPTGAAYTKAELKALTDVLVKHPHVWIMTDDMYEHLVYDDFVFTTPAQIEPSLFDRTLTVNGVSK
AYCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPCSIAQWAAVEALNGPQHFIPENNKVFKERRDLVVSMLNQASGIECPR
PEGAFYVYPSCAGTIGKTTPSGKVIDNDQTFVTELLETEGVAVVQGSAFGLGPAFRISYATKTSDLEDACKRIQRFCGNL
R

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=392, Percent_Identity=28.3163265306122, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=28.3163265306122, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI95147551, Length=363, Percent_Identity=28.3746556473829, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881279, Length=363, Percent_Identity=28.3746556473829, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881281, Length=360, Percent_Identity=25, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4507369, Length=391, Percent_Identity=24.0409207161125, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1788627, Length=390, Percent_Identity=28.4615384615385, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786816, Length=380, Percent_Identity=27.6315789473684, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1788722, Length=372, Percent_Identity=30.3763440860215, Blast_Score=127, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71994472, Length=362, Percent_Identity=29.8342541436464, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=362, Percent_Identity=29.8342541436464, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17567369, Length=403, Percent_Identity=25.5583126550869, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=404, Percent_Identity=23.5148514851485, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=315, Percent_Identity=29.8412698412698, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320317, Length=366, Percent_Identity=23.7704918032787, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323118, Length=365, Percent_Identity=22.1917808219178, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573069, Length=391, Percent_Identity=26.3427109974425, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24646114, Length=391, Percent_Identity=26.3427109974425, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573067, Length=391, Percent_Identity=26.3427109974425, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573065, Length=391, Percent_Identity=26.3427109974425, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18859735, Length=390, Percent_Identity=25.1282051282051, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45551451, Length=394, Percent_Identity=24.3654822335025, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641770, Length=394, Percent_Identity=24.3654822335025, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641760, Length=394, Percent_Identity=24.3654822335025, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641768, Length=394, Percent_Identity=24.3654822335025, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641766, Length=394, Percent_Identity=24.3654822335025, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641764, Length=394, Percent_Identity=24.3654822335025, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43276; Mature: 43276

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSFLAAALDRVKPSATIAVTDKARVLKAAGRNVIGLGAGEPDFDTPDNIKQAAIKAIQD
CHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHC
GKTKYTAVDGIPELKDAIIGKFQRENGLTYKPNQVIVGVGGKQVLYNALMATINPGDEVI
CCCEEEEECCCHHHHHHHHHHHHHCCCCEECCCEEEEECCCHHHHHHHHHHCCCCCCCEE
IPAPYWVSYPEMVALAGGEPVPVVCTSAHGFKLQPEALEKAITPKTKWLILCSPSNPTGA
ECCCCCCCCCCEEEECCCCCCEEEEECCCCCEECHHHHHHHCCCCCEEEEEECCCCCCCC
AYTKAELKALTDVLVKHPHVWIMTDDMYEHLVYDDFVFTTPAQIEPSLFDRTLTVNGVSK
CCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCEEECCCCCCCHHHHCCEEEECCCCC
AYCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPCSIAQWAAVEALNGPQHFIPENNKVFK
EEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHCCCCCCHHHH
ERRDLVVSMLNQASGIECPRPEGAFYVYPSCAGTIGKTTPSGKVIDNDQTFVTELLETEG
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCC
VAVVQGSAFGLGPAFRISYATKTSDLEDACKRIQRFCGNLR
EEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMSFLAAALDRVKPSATIAVTDKARVLKAAGRNVIGLGAGEPDFDTPDNIKQAAIKAIQD
CHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHC
GKTKYTAVDGIPELKDAIIGKFQRENGLTYKPNQVIVGVGGKQVLYNALMATINPGDEVI
CCCEEEEECCCHHHHHHHHHHHHHCCCCEECCCEEEEECCCHHHHHHHHHHCCCCCCCEE
IPAPYWVSYPEMVALAGGEPVPVVCTSAHGFKLQPEALEKAITPKTKWLILCSPSNPTGA
ECCCCCCCCCCEEEECCCCCCEEEEECCCCCEECHHHHHHHCCCCCEEEEEECCCCCCCC
AYTKAELKALTDVLVKHPHVWIMTDDMYEHLVYDDFVFTTPAQIEPSLFDRTLTVNGVSK
CCHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCEEECCCCCCCHHHHCCEEEECCCCC
AYCMTGWRIGYAGGPAQLIKAMATIQSQSTSNPCSIAQWAAVEALNGPQHFIPENNKVFK
EEEECCCEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHCCCCCCHHHH
ERRDLVVSMLNQASGIECPRPEGAFYVYPSCAGTIGKTTPSGKVIDNDQTFVTELLETEG
HHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCC
VAVVQGSAFGLGPAFRISYATKTSDLEDACKRIQRFCGNLR
EEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA