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The map label for this gene is fabG [H]

Identifier: 146342039

GI number: 146342039

Start: 5386601

End: 5387341

Strand: Direct

Name: fabG [H]

Synonym: BRADO5178

Alternate gene names: 146342039

Gene position: 5386601-5387341 (Clockwise)

Preceding gene: 146342038

Following gene: 146342040

Centisome position: 72.24

GC content: 65.99

Gene sequence:

>741_bases
ATGACCGTGCATGCTGTGGTGATTGGCGGCACCCGCGGCCTCGGTCGCGTTGTCGTCGAGCGCTTCCTGGCCCGAGGCTG
CGCCGTCAGCGTGGTATCGCGGCAACGTCCGGCCGATTTCCCAGAGCAGCCCGGCCTGGCGCATTTCGCAGCCGATCTTG
AGCGCAGCGACAGTTTTGCCGGGCTCTGGCGCGAGATCGCTGATGGCCACGGTCCCGTGCGCTACCTCGTCCTGAGCCAG
CGCTTCCGCGGTCAAGGCGATCCCTGGGCCGGCGAAATCCAGGTCGGCCTGACCGCTTCGCGCGACCTGATCGAAGGGTT
TTCCGGCCATTTCGCAGAGGCTGGCGACCGCGCCATCGGCGTGGTCAGCTCGGTTTACGCCGAATTCGTTGGCTCGTCGC
AGCCGGTCGGCTATCACGTCGTCAAGGGTGGCCTGAACGCGATGGTCCGCCATTATGCCGCCACCCTCGGCCGGCGCGGC
ATCCGCGTCAACGCGATCATGCCGCTCACGTATTTGAAGCGCGAATCGCGGACCTTCTACGAGCAGAACGAGAAGCTCAT
GGAGACGTACCGCCGGCTTGTCCCGCTCGGCCGGCTCGGGACCGCCGAGGAATGCGCCGACGCGCTGGATTTCCTGTGCA
GCGAACGCGCCTCGTTCATCAACGGGCAGAGCCTGTTCCTCGACGGCGGAGTGTCCACAGTCTGGCAAGAAGAGGTCGCC
AAGAGCTTCGCGGGCCTGTAA

Upstream 100 bases:

>100_bases
TGTTCGCCGACTTCGCGCCAGAGGACAGCGACACCACCAAGGTCGCGGCCTACCAGGCCGAGCTCGCCCGCCGCGTCGCC
GACCTGCAGGATGCTGCAGC

Downstream 100 bases:

>100_bases
AACGCGCCGCAAATTCGCTTCGGCCTACCATCCCGCCTGCGGGACCGCCAACCCAGGATCGCGACATCATGCAGCACGTG
AAGCACAAGACCGATTGCCG

Product: putative short-chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTVHAVVIGGTRGLGRVVVERFLARGCAVSVVSRQRPADFPEQPGLAHFAADLERSDSFAGLWREIADGHGPVRYLVLSQ
RFRGQGDPWAGEIQVGLTASRDLIEGFSGHFAEAGDRAIGVVSSVYAEFVGSSQPVGYHVVKGGLNAMVRHYAATLGRRG
IRVNAIMPLTYLKRESRTFYEQNEKLMETYRRLVPLGRLGTAEECADALDFLCSERASFINGQSLFLDGGVSTVWQEEVA
KSFAGL

Sequences:

>Translated_246_residues
MTVHAVVIGGTRGLGRVVVERFLARGCAVSVVSRQRPADFPEQPGLAHFAADLERSDSFAGLWREIADGHGPVRYLVLSQ
RFRGQGDPWAGEIQVGLTASRDLIEGFSGHFAEAGDRAIGVVSSVYAEFVGSSQPVGYHVVKGGLNAMVRHYAATLGRRG
IRVNAIMPLTYLKRESRTFYEQNEKLMETYRRLVPLGRLGTAEECADALDFLCSERASFINGQSLFLDGGVSTVWQEEVA
KSFAGL
>Mature_245_residues
TVHAVVIGGTRGLGRVVVERFLARGCAVSVVSRQRPADFPEQPGLAHFAADLERSDSFAGLWREIADGHGPVRYLVLSQR
FRGQGDPWAGEIQVGLTASRDLIEGFSGHFAEAGDRAIGVVSSVYAEFVGSSQPVGYHVVKGGLNAMVRHYAATLGRRGI
RVNAIMPLTYLKRESRTFYEQNEKLMETYRRLVPLGRLGTAEECADALDFLCSERASFINGQSLFLDGGVSTVWQEEVAK
SFAGL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=23.9043824701195, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=26.1410788381743, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=25.3061224489796, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=242, Percent_Identity=23.5537190082645, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=26.7206477732794, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26822; Mature: 26691

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHAVVIGGTRGLGRVVVERFLARGCAVSVVSRQRPADFPEQPGLAHFAADLERSDSFA
CEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHH
GLWREIADGHGPVRYLVLSQRFRGQGDPWAGEIQVGLTASRDLIEGFSGHFAEAGDRAIG
HHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHCCCHHHCCCHHHH
VVSSVYAEFVGSSQPVGYHVVKGGLNAMVRHYAATLGRRGIRVNAIMPLTYLKRESRTFY
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
EQNEKLMETYRRLVPLGRLGTAEECADALDFLCSERASFINGQSLFLDGGVSTVWQEEVA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
KSFAGL
HHHCCC
>Mature Secondary Structure 
TVHAVVIGGTRGLGRVVVERFLARGCAVSVVSRQRPADFPEQPGLAHFAADLERSDSFA
EEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHH
GLWREIADGHGPVRYLVLSQRFRGQGDPWAGEIQVGLTASRDLIEGFSGHFAEAGDRAIG
HHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHCCCHHHCCCHHHH
VVSSVYAEFVGSSQPVGYHVVKGGLNAMVRHYAATLGRRGIRVNAIMPLTYLKRESRTFY
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
EQNEKLMETYRRLVPLGRLGTAEECADALDFLCSERASFINGQSLFLDGGVSTVWQEEVA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
KSFAGL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]