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The map label for this gene is dxs [C]

Identifier: 146342032

GI number: 146342032

Start: 5380255

End: 5381178

Strand: Direct

Name: dxs [C]

Synonym: BRADO5170

Alternate gene names: 146342032

Gene position: 5380255-5381178 (Clockwise)

Preceding gene: 146342031

Following gene: 146342033

Centisome position: 72.15

GC content: 63.2

Gene sequence:

>924_bases
ATGAGAAACGCGTTCGCGGACGAACTGACCAAGCTCGGCAATGACGACCCGCGCGTCGTGATGCTGTCGGGCGACATCGG
CAATCGCCTGTTCGACAAGTTCAAGGACAAGCATCCGAGCCGCTTCTTCAACTGCGGCGTCGCCGAAGCCAACATGATGG
GCGTCGCCGCCGGCATGGCGATGAACGGCCTGCGCCCGGTCGCCTATACGATCACCCCGTTCGTGACGACGCGCTGCCTG
GAGCAGATCCGCACCGACGTCTGCTATCACGAGGCGCCGGTGACCATCGTCGCCGTCGGCGCCGGCCTCGCCTATTCCGG
CCTCGGCCCGACCCATCACGCCTGCGAGGATATTTCGTTCCTGCGCTCGATCCCGAACATGGTCGTGATCTGCCCGGGCG
ATGCCTTCGAGGTACGCGGCGCGCTGCGCGCGGCGATGCAGCAGGACCGGCCGGTCTATATCCGCATGGGCAAGAAGGGT
GAGCCTGTCGTTCACAAGGGACCCATCGCGGATTTCAAGATCGGCAAGGCGATCACGATCGAGGAAGGCTCGGACGTGTG
CCTGCTCTCGACCGGCAACATGCTGCCGGAAGCCATTGAGGCCGCACACAGATTGAAGGAAAAGGGCATCTCCGCCGAGG
TCGTCAGCTTCCACACCGTGAAGCCGCTGGATGAGGACAAGCTCAAGCAGGCCTTCAGCCGCTTCAAGCTGGTCGCGACC
ATCGAGGAGCATTCGCTGATCGGCGGCTTCGGCGCGGCGGTCTCCGAGTGGCTCGTCGACAGCGAGACGCAGTCAAAAAA
GTTCCTGCGGTTCGGGACGCCCGATGCGTTCTTCAAGAAATCCGGTGAACAGGAATATGCCCGCGAGGTGCTCGGCCTGA
CCGGCCACCAGATCGCGGACAAGATCATCCACGCCTTGAGCTGA

Upstream 100 bases:

>100_bases
AGGGCAAGGGCGTGTCGTTCATGGAAGACGACAACAACTGGCACTATCGCGCCCCCACCGCTGAGGAAGTCGTCAAGTCG
TTCAAGGAGCTCGGCCTGTC

Downstream 100 bases:

>100_bases
GACATCACATGAAGACCCAAGCTGCCCTCCTGGTCCAGACCGGCCAGCCGCTCGTGCTCGCCGAGATCGAGACCCCTGCC
TTGAAGCCGGGCCAGGTGCT

Product: putative transketolase, C-terminal section (TK)

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRNAFADELTKLGNDDPRVVMLSGDIGNRLFDKFKDKHPSRFFNCGVAEANMMGVAAGMAMNGLRPVAYTITPFVTTRCL
EQIRTDVCYHEAPVTIVAVGAGLAYSGLGPTHHACEDISFLRSIPNMVVICPGDAFEVRGALRAAMQQDRPVYIRMGKKG
EPVVHKGPIADFKIGKAITIEEGSDVCLLSTGNMLPEAIEAAHRLKEKGISAEVVSFHTVKPLDEDKLKQAFSRFKLVAT
IEEHSLIGGFGAAVSEWLVDSETQSKKFLRFGTPDAFFKKSGEQEYAREVLGLTGHQIADKIIHALS

Sequences:

>Translated_307_residues
MRNAFADELTKLGNDDPRVVMLSGDIGNRLFDKFKDKHPSRFFNCGVAEANMMGVAAGMAMNGLRPVAYTITPFVTTRCL
EQIRTDVCYHEAPVTIVAVGAGLAYSGLGPTHHACEDISFLRSIPNMVVICPGDAFEVRGALRAAMQQDRPVYIRMGKKG
EPVVHKGPIADFKIGKAITIEEGSDVCLLSTGNMLPEAIEAAHRLKEKGISAEVVSFHTVKPLDEDKLKQAFSRFKLVAT
IEEHSLIGGFGAAVSEWLVDSETQSKKFLRFGTPDAFFKKSGEQEYAREVLGLTGHQIADKIIHALS
>Mature_307_residues
MRNAFADELTKLGNDDPRVVMLSGDIGNRLFDKFKDKHPSRFFNCGVAEANMMGVAAGMAMNGLRPVAYTITPFVTTRCL
EQIRTDVCYHEAPVTIVAVGAGLAYSGLGPTHHACEDISFLRSIPNMVVICPGDAFEVRGALRAAMQQDRPVYIRMGKKG
EPVVHKGPIADFKIGKAITIEEGSDVCLLSTGNMLPEAIEAAHRLKEKGISAEVVSFHTVKPLDEDKLKQAFSRFKLVAT
IEEHSLIGGFGAAVSEWLVDSETQSKKFLRFGTPDAFFKKSGEQEYAREVLGLTGHQIADKIIHALS

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=263, Percent_Identity=32.319391634981, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI4507521, Length=263, Percent_Identity=32.319391634981, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI133778974, Length=250, Percent_Identity=34, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI225637463, Length=304, Percent_Identity=29.9342105263158, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI225637459, Length=304, Percent_Identity=29.9342105263158, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI225637461, Length=304, Percent_Identity=29.9342105263158, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI156564403, Length=237, Percent_Identity=24.8945147679325, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4557353, Length=293, Percent_Identity=24.9146757679181, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI34101272, Length=293, Percent_Identity=24.9146757679181, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI291084858, Length=231, Percent_Identity=23.3766233766234, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786622, Length=271, Percent_Identity=32.1033210332103, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17539652, Length=292, Percent_Identity=34.2465753424658, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17538422, Length=251, Percent_Identity=27.4900398406374, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319698, Length=286, Percent_Identity=24.4755244755245, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666278, Length=303, Percent_Identity=31.023102310231, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24645119, Length=310, Percent_Identity=30.3225806451613, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI45551847, Length=310, Percent_Identity=30.3225806451613, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI45550715, Length=310, Percent_Identity=30.3225806451613, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21358145, Length=284, Percent_Identity=27.112676056338, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24650940, Length=284, Percent_Identity=27.112676056338, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 33510; Mature: 33510

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNAFADELTKLGNDDPRVVMLSGDIGNRLFDKFKDKHPSRFFNCGVAEANMMGVAAGMA
CCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHH
MNGLRPVAYTITPFVTTRCLEQIRTDVCYHEAPVTIVAVGAGLAYSGLGPTHHACEDISF
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEECCCCCCHHHHHHHHH
LRSIPNMVVICPGDAFEVRGALRAAMQQDRPVYIRMGKKGEPVVHKGPIADFKIGKAITI
HHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCEECCCEEEE
EEGSDVCLLSTGNMLPEAIEAAHRLKEKGISAEVVSFHTVKPLDEDKLKQAFSRFKLVAT
ECCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEE
IEEHSLIGGFGAAVSEWLVDSETQSKKFLRFGTPDAFFKKSGEQEYAREVLGLTGHQIAD
EHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHH
KIIHALS
HHHHHCC
>Mature Secondary Structure
MRNAFADELTKLGNDDPRVVMLSGDIGNRLFDKFKDKHPSRFFNCGVAEANMMGVAAGMA
CCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHH
MNGLRPVAYTITPFVTTRCLEQIRTDVCYHEAPVTIVAVGAGLAYSGLGPTHHACEDISF
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEECCCCCCHHHHHHHHH
LRSIPNMVVICPGDAFEVRGALRAAMQQDRPVYIRMGKKGEPVVHKGPIADFKIGKAITI
HHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCEECCCEEEE
EEGSDVCLLSTGNMLPEAIEAAHRLKEKGISAEVVSFHTVKPLDEDKLKQAFSRFKLVAT
ECCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEE
IEEHSLIGGFGAAVSEWLVDSETQSKKFLRFGTPDAFFKKSGEQEYAREVLGLTGHQIAD
EHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCCHHHHHH
KIIHALS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]