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The map label for this gene is tktB [C]

Identifier: 146342031

GI number: 146342031

Start: 5379410

End: 5380258

Strand: Direct

Name: tktB [C]

Synonym: BRADO5169

Alternate gene names: 146342031

Gene position: 5379410-5380258 (Clockwise)

Preceding gene: 146342030

Following gene: 146342032

Centisome position: 72.14

GC content: 67.26

Gene sequence:

>849_bases
ATGAACGTGGCAGTCCGGAACACCGCGGCCAAGCCCGACGTGGCCGCCCTGAAGGCGCAGGCCGCGAAGCTGCGCGGCAA
GATCATCGAGATGTCGCACAAGGCGCAGGCCGCCCATCTCGCCTCGTCGCTGTCCTGCGCCGATGCGATGACCGCCGCCT
ATTGGCACGTCCTGAACATCGACCCCAAGAACCCGACCGATCCGCTGCGCGATCGCTTCATCCTGTCGAAGGGCCACGCC
GCCGCGGCGCTGTTCGCGACGCTCGCGATGAAGGGCTACTTCCCGATCGAGGAGCTCGACACCTACTGCCAGGACGGCGG
CCGGCTCGCCGAGCATCCGCCGGCGAACCTCTTGCCCGGCGTCGAGGCCGCCACCGGCTCGCTCGGCCACGGCCTGCCGC
TCGGCTGCGGCATGGCGCTGGCCGGCCGCATCAAGGGCGAGAATTTTCGCGTGTTCGCGCTGCTCTCCGACGGCGAGAAC
AACGAAGGTTCGGTGTGGGAGGCCGCGATGTTCGCCGCCGCCCAGAAGCTCGAGAACGTCTGCGTCGTCGTCGACTACAA
CAAGTGGCAGGCGACCGCGCGCTCCAACGAGACCCTGATGCTGGCGCCGCTGCGCGACAAATGGGCCGCGTTCGGCTGGG
ACGCGCACGAGATCGACGGCCATGATGTCGGCGCGCTGGCGGAGGCCATGCAGAACATTCCGAACGGCTCGGGCAAGCCG
GTGGCGCTGATCGCCCATACCATGAAGGGCAAGGGCGTGTCGTTCATGGAAGACGACAACAACTGGCACTATCGCGCCCC
CACCGCTGAGGAAGTCGTCAAGTCGTTCAAGGAGCTCGGCCTGTCATGA

Upstream 100 bases:

>100_bases
GCGGCGCTTCGAGGATGTCATGAACAAGCTGCCGACCAAGTACGAGCATAAACCCTGATCTATACCTGCGCCTCCCCGGG
AGGCGCGACTGGAGAGCACG

Downstream 100 bases:

>100_bases
GAAACGCGTTCGCGGACGAACTGACCAAGCTCGGCAATGACGACCCGCGCGTCGTGATGCTGTCGGGCGACATCGGCAAT
CGCCTGTTCGACAAGTTCAA

Product: putative transketolase N-terminal section (TK)

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNVAVRNTAAKPDVAALKAQAAKLRGKIIEMSHKAQAAHLASSLSCADAMTAAYWHVLNIDPKNPTDPLRDRFILSKGHA
AAALFATLAMKGYFPIEELDTYCQDGGRLAEHPPANLLPGVEAATGSLGHGLPLGCGMALAGRIKGENFRVFALLSDGEN
NEGSVWEAAMFAAAQKLENVCVVVDYNKWQATARSNETLMLAPLRDKWAAFGWDAHEIDGHDVGALAEAMQNIPNGSGKP
VALIAHTMKGKGVSFMEDDNNWHYRAPTAEEVVKSFKELGLS

Sequences:

>Translated_282_residues
MNVAVRNTAAKPDVAALKAQAAKLRGKIIEMSHKAQAAHLASSLSCADAMTAAYWHVLNIDPKNPTDPLRDRFILSKGHA
AAALFATLAMKGYFPIEELDTYCQDGGRLAEHPPANLLPGVEAATGSLGHGLPLGCGMALAGRIKGENFRVFALLSDGEN
NEGSVWEAAMFAAAQKLENVCVVVDYNKWQATARSNETLMLAPLRDKWAAFGWDAHEIDGHDVGALAEAMQNIPNGSGKP
VALIAHTMKGKGVSFMEDDNNWHYRAPTAEEVVKSFKELGLS
>Mature_282_residues
MNVAVRNTAAKPDVAALKAQAAKLRGKIIEMSHKAQAAHLASSLSCADAMTAAYWHVLNIDPKNPTDPLRDRFILSKGHA
AAALFATLAMKGYFPIEELDTYCQDGGRLAEHPPANLLPGVEAATGSLGHGLPLGCGMALAGRIKGENFRVFALLSDGEN
NEGSVWEAAMFAAAQKLENVCVVVDYNKWQATARSNETLMLAPLRDKWAAFGWDAHEIDGHDVGALAEAMQNIPNGSGKP
VALIAHTMKGKGVSFMEDDNNWHYRAPTAEEVVKSFKELGLS

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=258, Percent_Identity=37.2093023255814, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI205277463, Length=258, Percent_Identity=37.5968992248062, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI4507521, Length=258, Percent_Identity=37.5968992248062, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI225637459, Length=258, Percent_Identity=29.4573643410853, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI225637461, Length=258, Percent_Identity=29.8449612403101, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI225637463, Length=215, Percent_Identity=30.2325581395349, Blast_Score=115, Evalue=3e-26,
Organism=Escherichia coli, GI1788808, Length=275, Percent_Identity=29.8181818181818, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI48994911, Length=256, Percent_Identity=27.734375, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17539652, Length=265, Percent_Identity=37.3584905660377, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6325331, Length=249, Percent_Identity=30.1204819277108, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319593, Length=277, Percent_Identity=27.0758122743682, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45551847, Length=269, Percent_Identity=38.2899628252788, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI45550715, Length=269, Percent_Identity=38.2899628252788, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24666278, Length=251, Percent_Identity=37.8486055776892, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24645119, Length=233, Percent_Identity=39.0557939914163, Blast_Score=164, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30233; Mature: 30233

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVAVRNTAAKPDVAALKAQAAKLRGKIIEMSHKAQAAHLASSLSCADAMTAAYWHVLNI
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
DPKNPTDPLRDRFILSKGHAAAALFATLAMKGYFPIEELDTYCQDGGRLAEHPPANLLPG
CCCCCCCHHHHHEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
VEAATGSLGHGLPLGCGMALAGRIKGENFRVFALLSDGENNEGSVWEAAMFAAAQKLENV
CCCCCCCCCCCCCCCCCHHHHCEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCE
CVVVDYNKWQATARSNETLMLAPLRDKWAAFGWDAHEIDGHDVGALAEAMQNIPNGSGKP
EEEEECCCHHHHCCCCCEEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCE
VALIAHTMKGKGVSFMEDDNNWHYRAPTAEEVVKSFKELGLS
EEEEEEECCCCCCEEEECCCCEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVAVRNTAAKPDVAALKAQAAKLRGKIIEMSHKAQAAHLASSLSCADAMTAAYWHVLNI
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEE
DPKNPTDPLRDRFILSKGHAAAALFATLAMKGYFPIEELDTYCQDGGRLAEHPPANLLPG
CCCCCCCHHHHHEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
VEAATGSLGHGLPLGCGMALAGRIKGENFRVFALLSDGENNEGSVWEAAMFAAAQKLENV
CCCCCCCCCCCCCCCCCHHHHCEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCE
CVVVDYNKWQATARSNETLMLAPLRDKWAAFGWDAHEIDGHDVGALAEAMQNIPNGSGKP
EEEEECCCHHHHCCCCCEEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCE
VALIAHTMKGKGVSFMEDDNNWHYRAPTAEEVVKSFKELGLS
EEEEEEECCCCCCEEEECCCCEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]