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The map label for this gene is gmhA [H]

Identifier: 146342029

GI number: 146342029

Start: 5377724

End: 5378356

Strand: Direct

Name: gmhA [H]

Synonym: BRADO5167

Alternate gene names: 146342029

Gene position: 5377724-5378356 (Clockwise)

Preceding gene: 146342028

Following gene: 146342030

Centisome position: 72.12

GC content: 63.19

Gene sequence:

>633_bases
ATGGATGGAGAAGGAGGTCGTGAAATGAACGTTCTCGCCTTCAAGACTCCCGGCAGCCTGTTCGCCGACTACACCAGCCG
CTTCAGCACCGTGCTGAAGGATTTCGACTGGGCCCCCGTCGAGAAGCTCGCCTACGATCTGCGCGACTGCTGGCAGACCG
GCCGTCAGGTGTTCTTCTGCGGCAATGGCGGCAGCGGCGGCAACGCCAACCATCTCGCCAACGACTTCCTCTACGCGCTG
TCGAAGACGCCGGGCTCCGGCCTGCGCGTGCATTCGCTGTCGTCGAACCCGTCGGTCATCACCTGCCTCGCCAATGACGA
AGGCTACGACCAGGTGTTCTCGCTGCAACTCGCGGTGCTCGCGCGCAAGGGCGACGTGCTGATCACCTTCTCCGGCTCCG
GCAATTCGCCGAACATCCTGAAGGCGCTCGAAGAGGGCAAGAAGATCGGCATGACCTCCTACGCCGTGCTCGGCTTCACC
GGCGGCAAGGCCAAGGCGCTGGCCGACGTGCCGATCCATTTCGCTGTTGACGACATGCAGATCGCCGAGGACGCGCAGAT
GGTGATCGGCCACATGATCATGCAGTGGCTGTACGCCCAGCGTGGCGACATCATCACGACGCGCGAGGTCTGA

Upstream 100 bases:

>100_bases
GCTTCCGTCCGAAGAAGACGGTGGAGGACGCGATCAAGGAAATCATCGGCATGTACTCGCAAGGCGCCCTCAAGAACGAG
GACCGCTGGTACAATCTGAA

Downstream 100 bases:

>100_bases
CGGACAGGGACGATGGCTGCGAACGAAAAGTACCTGATCCTCGGCTCGAACTCCTTCTCGGGCGCAACCTTCGTCGACTT
CCTGGCCGCGGCCGGTCACG

Product: putative phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MDGEGGREMNVLAFKTPGSLFADYTSRFSTVLKDFDWAPVEKLAYDLRDCWQTGRQVFFCGNGGSGGNANHLANDFLYAL
SKTPGSGLRVHSLSSNPSVITCLANDEGYDQVFSLQLAVLARKGDVLITFSGSGNSPNILKALEEGKKIGMTSYAVLGFT
GGKAKALADVPIHFAVDDMQIAEDAQMVIGHMIMQWLYAQRGDIITTREV

Sequences:

>Translated_210_residues
MDGEGGREMNVLAFKTPGSLFADYTSRFSTVLKDFDWAPVEKLAYDLRDCWQTGRQVFFCGNGGSGGNANHLANDFLYAL
SKTPGSGLRVHSLSSNPSVITCLANDEGYDQVFSLQLAVLARKGDVLITFSGSGNSPNILKALEEGKKIGMTSYAVLGFT
GGKAKALADVPIHFAVDDMQIAEDAQMVIGHMIMQWLYAQRGDIITTREV
>Mature_210_residues
MDGEGGREMNVLAFKTPGSLFADYTSRFSTVLKDFDWAPVEKLAYDLRDCWQTGRQVFFCGNGGSGGNANHLANDFLYAL
SKTPGSGLRVHSLSSNPSVITCLANDEGYDQVFSLQLAVLARKGDVLITFSGSGNSPNILKALEEGKKIGMTSYAVLGFT
GGKAKALADVPIHFAVDDMQIAEDAQMVIGHMIMQWLYAQRGDIITTREV

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=169, Percent_Identity=33.1360946745562, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789539, Length=148, Percent_Identity=31.7567567567568, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 22740; Mature: 22740

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGEGGREMNVLAFKTPGSLFADYTSRFSTVLKDFDWAPVEKLAYDLRDCWQTGRQVFFC
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEE
GNGGSGGNANHLANDFLYALSKTPGSGLRVHSLSSNPSVITCLANDEGYDQVFSLQLAVL
ECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHEEE
ARKGDVLITFSGSGNSPNILKALEEGKKIGMTSYAVLGFTGGKAKALADVPIHFAVDDMQ
ECCCCEEEEEECCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCCEEEEECCHH
IAEDAQMVIGHMIMQWLYAQRGDIITTREV
HHHHHHHHHHHHHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MDGEGGREMNVLAFKTPGSLFADYTSRFSTVLKDFDWAPVEKLAYDLRDCWQTGRQVFFC
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEE
GNGGSGGNANHLANDFLYALSKTPGSGLRVHSLSSNPSVITCLANDEGYDQVFSLQLAVL
ECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHEEE
ARKGDVLITFSGSGNSPNILKALEEGKKIGMTSYAVLGFTGGKAKALADVPIHFAVDDMQ
ECCCCEEEEEECCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCCEEEECCCEEEEECCHH
IAEDAQMVIGHMIMQWLYAQRGDIITTREV
HHHHHHHHHHHHHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]