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The map label for this gene is mpg1 [H]

Identifier: 146342027

GI number: 146342027

Start: 5375995

End: 5376717

Strand: Direct

Name: mpg1 [H]

Synonym: BRADO5165

Alternate gene names: 146342027

Gene position: 5375995-5376717 (Clockwise)

Preceding gene: 146342026

Following gene: 146342028

Centisome position: 72.1

GC content: 63.62

Gene sequence:

>723_bases
ATGCGTGCCCTTCTGCTCGCCGCTGGCATTGGAAGCCGGCTGCGCCCGCTGACCAATACGACGCCAAAATGCCTGGTGCG
TGTGCACGACAGGCCGCTCTTGGACTACTGGCTCGACCTCGTGTTCGAGGGCGGCGTCGAGCGCGCGCTGTTGAACACGC
ACTGGCTGGCCGAGCAGGTCCGCGCCCATGTCGCGCAGTCGCGATGGCGCGACCGGATCGATCTCGTTCACGAAGATGAA
CTGCTCGGCACCGGCGGCACCGTGCTCGCCAATCGCGCCTGGTTCGGCGACCAGCCGTTCGTGGTGGCCCATGCAGACAA
TCTGACCGATTTCGACGTCAAGGGGCTGCTCGCCGCGCATCAGGGCCGGCCCGACGGCTGCATCATGACGATGCTGGCCT
TCCGGACCGACGATCCGAGCTCGTGCGGGATTCTCGAGCTGGATGCTCAGCGCCGCGTGATCGCCTTCTACGAGAAGGTC
AAGAATCCGCCCGGGAACCTCGCAAATGGCGCGGTCTACGTGTTTGATCCCAGTGTCATCGCCGACATCGCGGCGCTCGG
AAAGCCGGTCGTCGATCTCTCCACCGAAATCATCCCCAACTATCTCGGACGCATTTTATGCGTCGAAACCCGCGGTTATC
ATCGGGATATCGGCAACCCGGAAAGCTTGCGCCGGGCTCATTTGGAGTTTAAGCACGAACCGCGCCGTGGCGGGGACGCT
TGA

Upstream 100 bases:

>100_bases
CTCCCGAGTCGGCAACCTGCCGCTGACGACCGCCGAACTGGTGCGCGAGATCGACGAGACGGGGTTCAGCCAGGAATAAA
TCCCAGAGTAGGATGCCGTC

Downstream 100 bases:

>100_bases
CGGGCGGCTGTGGCTGCCTCCCCCACCAATTTGCATAAAGGTGCGCGCGACGCGCCAGCCGGCGAGACGACAGGCGAGCC
ACGGGGATTGCGCAGATGAA

Product: putative sugar-phosphate nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRALLLAAGIGSRLRPLTNTTPKCLVRVHDRPLLDYWLDLVFEGGVERALLNTHWLAEQVRAHVAQSRWRDRIDLVHEDE
LLGTGGTVLANRAWFGDQPFVVAHADNLTDFDVKGLLAAHQGRPDGCIMTMLAFRTDDPSSCGILELDAQRRVIAFYEKV
KNPPGNLANGAVYVFDPSVIADIAALGKPVVDLSTEIIPNYLGRILCVETRGYHRDIGNPESLRRAHLEFKHEPRRGGDA

Sequences:

>Translated_240_residues
MRALLLAAGIGSRLRPLTNTTPKCLVRVHDRPLLDYWLDLVFEGGVERALLNTHWLAEQVRAHVAQSRWRDRIDLVHEDE
LLGTGGTVLANRAWFGDQPFVVAHADNLTDFDVKGLLAAHQGRPDGCIMTMLAFRTDDPSSCGILELDAQRRVIAFYEKV
KNPPGNLANGAVYVFDPSVIADIAALGKPVVDLSTEIIPNYLGRILCVETRGYHRDIGNPESLRRAHLEFKHEPRRGGDA
>Mature_240_residues
MRALLLAAGIGSRLRPLTNTTPKCLVRVHDRPLLDYWLDLVFEGGVERALLNTHWLAEQVRAHVAQSRWRDRIDLVHEDE
LLGTGGTVLANRAWFGDQPFVVAHADNLTDFDVKGLLAAHQGRPDGCIMTMLAFRTDDPSSCGILELDAQRRVIAFYEKV
KNPPGNLANGAVYVFDPSVIADIAALGKPVVDLSTEIIPNYLGRILCVETRGYHRDIGNPESLRRAHLEFKHEPRRGGDA

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=243, Percent_Identity=28.3950617283951, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI11761619, Length=243, Percent_Identity=28.3950617283951, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI1790224, Length=227, Percent_Identity=22.0264317180617, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI133931050, Length=232, Percent_Identity=30.1724137931034, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320148, Length=249, Percent_Identity=26.5060240963855, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355443, Length=246, Percent_Identity=29.2682926829268, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644084, Length=246, Percent_Identity=29.2682926829268, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 26689; Mature: 26689

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALLLAAGIGSRLRPLTNTTPKCLVRVHDRPLLDYWLDLVFEGGVERALLNTHWLAEQV
CCEEEEECCCCCCCCCCCCCCHHHEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RAHVAQSRWRDRIDLVHEDELLGTGGTVLANRAWFGDQPFVVAHADNLTDFDVKGLLAAH
HHHHHHHHHHHHHCCEECCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHC
QGRPDGCIMTMLAFRTDDPSSCGILELDAQRRVIAFYEKVKNPPGNLANGAVYVFDPSVI
CCCCCHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCEEEEECCHHH
ADIAALGKPVVDLSTEIIPNYLGRILCVETRGYHRDIGNPESLRRAHLEFKHEPRRGGDA
HHHHHHCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRALLLAAGIGSRLRPLTNTTPKCLVRVHDRPLLDYWLDLVFEGGVERALLNTHWLAEQV
CCEEEEECCCCCCCCCCCCCCHHHEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RAHVAQSRWRDRIDLVHEDELLGTGGTVLANRAWFGDQPFVVAHADNLTDFDVKGLLAAH
HHHHHHHHHHHHHCCEECCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHC
QGRPDGCIMTMLAFRTDDPSSCGILELDAQRRVIAFYEKVKNPPGNLANGAVYVFDPSVI
CCCCCHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCEEEEECCHHH
ADIAALGKPVVDLSTEIIPNYLGRILCVETRGYHRDIGNPESLRRAHLEFKHEPRRGGDA
HHHHHHCCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]