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The map label for this gene is hbpA [H]

Identifier: 146338659

GI number: 146338659

Start: 1702811

End: 1704448

Strand: Reverse

Name: hbpA [H]

Synonym: BRADO1590

Alternate gene names: 146338659

Gene position: 1704448-1702811 (Counterclockwise)

Preceding gene: 146338660

Following gene: 146338658

Centisome position: 22.86

GC content: 65.38

Gene sequence:

>1638_bases
ATGACCAAGCTCACCCGTCGCAGCCTGCTCGGCGCCGGCGCCGCCATCGGCGGCAGCTTCATCCTGCCGCGCGTGTCGAT
CGCGCAGAGCGACAACCGTCCCTCGGTCACCATCGCCGTGCAGAAGGTGACCAACTCCAACGTGCTCGACGTGCTGCGCG
AGCAGTCCAATGTCGGCGAGCGCGTGTTCTACTCCTCGCTGTGGGAAAGCCTGATCTCGAAGAACTTCCGCGGCAATCTC
GAAGCCGTGCCCGGGCTCGCCACCGAGTGGAAGCGCATCGACGACCAGACCGTCGAATTGAAGCTGCGCCAGGGCGTCAA
GTTCCACAATGGCGACGAAATGACGTCGGAGGACGTCGTGTTCTCGTTCAGTCGCGAGCGCATGTTCGGCGACAGCGAGG
CCAAGAGCCGCACCACCATCAAGGCGTTCGAGAAGATCCCGACGCCGCGCCCTGGCAAGGAGCTGCCGCCGGACGTCATC
GGCGTCGCCCGCCGGATGTGGCCGGATCTCGTCCGCGTCGACGCGGTCGACAAATACACCGTGCGCTTCGTCAACGCGAC
GCCTGACGTGACCATCGAAGGCCGCCTGATGCGCTACGGCTCCGACATTATGAGCCGGCGCGGCTGGGAAGAGGCCGCGA
GCTATCTCGACTGGGCGCGCAAGCCGATCACCACGGGCCCCTACAAGATCGTCGAGTTCAAGCCGGACGTGTCGCTGACG
CTCGAAGCGCATGACGAATATTGGGGCGGCCGCCCGCCGCTGAAGCGGATCCGCTTCGTCGAGGTGCCGGAGGTCGCGAG
CCGCATCAACGGTCTCTTGTCCGGTGAGTATCAATTCGCCTGCGACATCCCGCCGGACCAGATCGCCGGCATCGAGAAGA
ATTCGGCGTTCGAGGTCCAGGGCGGCACCATCCTCAATCACCGCCTGACCGTGTTCGACAAGAACCATCCGCAGCTCGCC
AATCCCCTGGTGAGGCGCGCCTTCACCCATGCGATCGACCGCCAGGCGATCGTCGACAGCCTGTGGGCCGGCCGCACCCG
CGTGCCGAAGGGTCTGCAGTGGGAGTTCTACGGCGACATGTTCATCGCCGACTGGAGCGTGCCGGCGTTCGACCCGAAGC
TGGCGCAGGATCTTTTGAAGCAGGCCGGCTACAAGGGCGATCCGATCCCCTACCGCCTGCTCAACAACTACTACACCAAT
CAGGTCGCGACCGCCCAGGTGCTGGTCGAGATGTGGCAGGCGGTCGGCCTCAACGTCCAGATCGAGACCAAGGAGAACTG
GTCGCAGATCCTGGAGCGCGCCCCCACCCGCGCGGTGCGCGACTGGTCGAACTCGGCGGCGTTCAACGATCCGGTGTCGT
CGCTGGTCGCCCAGCACGGCCCCAACGGCCAGCAGCAGCAGGTCGGCGAATACACCAATGCCGAGTTGAACAAGCTGTCG
GAGTTCCTGGAGACGTCGACGGACCGCGCCGCGCGCAAGAAGGCGTTCGGCCGCATGCTGGAGATCGCCGAGCGCGAGGA
CCCGGCCTACACCGTGCTGCACCAGAACGCGACCTTCACGGCGAAGCCGAAGTCGATCAAGTGGAAGGCCTCGCCGGCCT
TCGCGATGGACTTCCGCAGCGGCAATTACGGAGCGTGA

Upstream 100 bases:

>100_bases
ACCACGATCACGTCAAGGCCGGCGCGGCGTACCTCGCCTCGCTCGAGCTCGCGCAATAACCAACGCCTTTCATTTCCTGA
CAACCTCACGAGAGATTGCC

Downstream 100 bases:

>100_bases
CGCCGTGGCGCCGCTGGTCAGCATCTCCGGCTTGAAGGTCGCCTTCGACGGCACACAAGTGCTGCATGGCATCGATCTCG
ACATCGCCAAGGGCGAGGCC

Product: putative oligopeptide ABC transporter substrate-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MTKLTRRSLLGAGAAIGGSFILPRVSIAQSDNRPSVTIAVQKVTNSNVLDVLREQSNVGERVFYSSLWESLISKNFRGNL
EAVPGLATEWKRIDDQTVELKLRQGVKFHNGDEMTSEDVVFSFSRERMFGDSEAKSRTTIKAFEKIPTPRPGKELPPDVI
GVARRMWPDLVRVDAVDKYTVRFVNATPDVTIEGRLMRYGSDIMSRRGWEEAASYLDWARKPITTGPYKIVEFKPDVSLT
LEAHDEYWGGRPPLKRIRFVEVPEVASRINGLLSGEYQFACDIPPDQIAGIEKNSAFEVQGGTILNHRLTVFDKNHPQLA
NPLVRRAFTHAIDRQAIVDSLWAGRTRVPKGLQWEFYGDMFIADWSVPAFDPKLAQDLLKQAGYKGDPIPYRLLNNYYTN
QVATAQVLVEMWQAVGLNVQIETKENWSQILERAPTRAVRDWSNSAAFNDPVSSLVAQHGPNGQQQQVGEYTNAELNKLS
EFLETSTDRAARKKAFGRMLEIAEREDPAYTVLHQNATFTAKPKSIKWKASPAFAMDFRSGNYGA

Sequences:

>Translated_545_residues
MTKLTRRSLLGAGAAIGGSFILPRVSIAQSDNRPSVTIAVQKVTNSNVLDVLREQSNVGERVFYSSLWESLISKNFRGNL
EAVPGLATEWKRIDDQTVELKLRQGVKFHNGDEMTSEDVVFSFSRERMFGDSEAKSRTTIKAFEKIPTPRPGKELPPDVI
GVARRMWPDLVRVDAVDKYTVRFVNATPDVTIEGRLMRYGSDIMSRRGWEEAASYLDWARKPITTGPYKIVEFKPDVSLT
LEAHDEYWGGRPPLKRIRFVEVPEVASRINGLLSGEYQFACDIPPDQIAGIEKNSAFEVQGGTILNHRLTVFDKNHPQLA
NPLVRRAFTHAIDRQAIVDSLWAGRTRVPKGLQWEFYGDMFIADWSVPAFDPKLAQDLLKQAGYKGDPIPYRLLNNYYTN
QVATAQVLVEMWQAVGLNVQIETKENWSQILERAPTRAVRDWSNSAAFNDPVSSLVAQHGPNGQQQQVGEYTNAELNKLS
EFLETSTDRAARKKAFGRMLEIAEREDPAYTVLHQNATFTAKPKSIKWKASPAFAMDFRSGNYGA
>Mature_544_residues
TKLTRRSLLGAGAAIGGSFILPRVSIAQSDNRPSVTIAVQKVTNSNVLDVLREQSNVGERVFYSSLWESLISKNFRGNLE
AVPGLATEWKRIDDQTVELKLRQGVKFHNGDEMTSEDVVFSFSRERMFGDSEAKSRTTIKAFEKIPTPRPGKELPPDVIG
VARRMWPDLVRVDAVDKYTVRFVNATPDVTIEGRLMRYGSDIMSRRGWEEAASYLDWARKPITTGPYKIVEFKPDVSLTL
EAHDEYWGGRPPLKRIRFVEVPEVASRINGLLSGEYQFACDIPPDQIAGIEKNSAFEVQGGTILNHRLTVFDKNHPQLAN
PLVRRAFTHAIDRQAIVDSLWAGRTRVPKGLQWEFYGDMFIADWSVPAFDPKLAQDLLKQAGYKGDPIPYRLLNNYYTNQ
VATAQVLVEMWQAVGLNVQIETKENWSQILERAPTRAVRDWSNSAAFNDPVSSLVAQHGPNGQQQQVGEYTNAELNKLSE
FLETSTDRAARKKAFGRMLEIAEREDPAYTVLHQNATFTAKPKSIKWKASPAFAMDFRSGNYGA

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=376, Percent_Identity=27.3936170212766, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1787551, Length=319, Percent_Identity=23.8244514106583, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787052, Length=381, Percent_Identity=23.6220472440945, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787762, Length=287, Percent_Identity=23.3449477351916, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61359; Mature: 61228

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLTRRSLLGAGAAIGGSFILPRVSIAQSDNRPSVTIAVQKVTNSNVLDVLREQSNVGE
CCCHHHHHHHHCCHHCCCCCCCCCEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHCCHH
RVFYSSLWESLISKNFRGNLEAVPGLATEWKRIDDQTVELKLRQGVKFHNGDEMTSEDVV
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHEEEHHHCCCCCCCCCCCCCCHHE
FSFSRERMFGDSEAKSRTTIKAFEKIPTPRPGKELPPDVIGVARRMWPDLVRVDAVDKYT
EEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCEEE
VRFVNATPDVTIEGRLMRYGSDIMSRRGWEEAASYLDWARKPITTGPYKIVEFKPDVSLT
EEEEECCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEE
LEAHDEYWGGRPPLKRIRFVEVPEVASRINGLLSGEYQFACDIPPDQIAGIEKNSAFEVQ
EEECCCCCCCCCCHHHEEEEECHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCEEEEC
GGTILNHRLTVFDKNHPQLANPLVRRAFTHAIDRQAIVDSLWAGRTRVPKGLQWEFYGDM
CCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCE
FIADWSVPAFDPKLAQDLLKQAGYKGDPIPYRLLNNYYTNQVATAQVLVEMWQAVGLNVQ
EEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEE
IETKENWSQILERAPTRAVRDWSNSAAFNDPVSSLVAQHGPNGQQQQVGEYTNAELNKLS
EECHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCHHHHHHHH
EFLETSTDRAARKKAFGRMLEIAEREDPAYTVLHQNATFTAKPKSIKWKASPAFAMDFRS
HHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCEEEECCCCEEEEECC
GNYGA
CCCCC
>Mature Secondary Structure 
TKLTRRSLLGAGAAIGGSFILPRVSIAQSDNRPSVTIAVQKVTNSNVLDVLREQSNVGE
CCHHHHHHHHCCHHCCCCCCCCCEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHCCHH
RVFYSSLWESLISKNFRGNLEAVPGLATEWKRIDDQTVELKLRQGVKFHNGDEMTSEDVV
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHEEEHHHCCCCCCCCCCCCCCHHE
FSFSRERMFGDSEAKSRTTIKAFEKIPTPRPGKELPPDVIGVARRMWPDLVRVDAVDKYT
EEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCEEE
VRFVNATPDVTIEGRLMRYGSDIMSRRGWEEAASYLDWARKPITTGPYKIVEFKPDVSLT
EEEEECCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEE
LEAHDEYWGGRPPLKRIRFVEVPEVASRINGLLSGEYQFACDIPPDQIAGIEKNSAFEVQ
EEECCCCCCCCCCHHHEEEEECHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCEEEEC
GGTILNHRLTVFDKNHPQLANPLVRRAFTHAIDRQAIVDSLWAGRTRVPKGLQWEFYGDM
CCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCE
FIADWSVPAFDPKLAQDLLKQAGYKGDPIPYRLLNNYYTNQVATAQVLVEMWQAVGLNVQ
EEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEE
IETKENWSQILERAPTRAVRDWSNSAAFNDPVSSLVAQHGPNGQQQQVGEYTNAELNKLS
EECHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCHHHHHHHH
EFLETSTDRAARKKAFGRMLEIAEREDPAYTVLHQNATFTAKPKSIKWKASPAFAMDFRS
HHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCEEEECCCCEEEEECC
GNYGA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]