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The map label for this gene is gudP [H]

Identifier: 146338638

GI number: 146338638

Start: 1679439

End: 1680794

Strand: Reverse

Name: gudP [H]

Synonym: BRADO1568

Alternate gene names: 146338638

Gene position: 1680794-1679439 (Counterclockwise)

Preceding gene: 146338642

Following gene: 146338637

Centisome position: 22.54

GC content: 65.34

Gene sequence:

>1356_bases
GTGCGCATGAGCGCGATCGTAACTACGGCAGGATTGCGCCGCTCGCGCGTGCGGCTGTTCATCGTGACCATGCTGTTCCT
GGTCACTACCGTGAACTACGCCGACCGCGCCACGCTCTCGATCGCGGGCCCCGCGCTCGCCAAGGATCTGCATCTCGATC
CGGTTGCGATGGGCTACGTGTTCTCCGCCTTCGGCTGGTCCTATGTGCTCGCGCAGGTGCCGGGCGGCTGGCTGCTCGAC
CGCTTCGGCTCGCGCTGGGTCTATGCCTGCAGCATCGTGATCTGGTCGATCTTCACCATGATGCAGGGCTGGATCGGCTT
CTTGTCCGGTGGCGCCGCGATCGTCGCGCTGTTCGCGCTGCGCTTCCTGGTCGGCCTTGCCGAGGCGCCGAGCTTCCCGG
CGAATGCCCGCATCGTCGCCGCCTGGTTTCCGAGCAATGAGCGCGGCACCGCGTCGGCCTTCTTCAACTCCGGGCAATAT
TTCGCGACCGTGATCTTCGCGCCGCTGATGGGCTGGATCGCGCACGAATTCGGCTGGCGCCACGTCTTCACCGTGATGGG
TGCGCTCGGCATCATCATGGGCCTGGTCTGGATCAGGACCATGTACGGGCCGAAGGAGCATCCTGGTATCAACGAGGCCG
AACTCGACTATATCAAGCAGGGCGGCGCGCTGGTCGACATGGAAGGCGCCAAGGACGAGACGAGAGACGGCAAGACCTCC
CAGGGCGGACCGACCTGGTCGCATATCGGCCAGCTGCTGTCGAACCGCATGATGCTCGGCGTCTATATCGGCCAGTACTG
TATCAACACGCTGACCTACTTCTTCCTCACCTGGTTCCCGGTCTATCTCGTCAAGGAGCGCGGCCTGTCGATCCTGCAGG
CGGGCTTCGTCGCCACCCTGCCGGCGCTGTGCGGCTTCATCGGCGGCGTGCTCGGCGGCTTCATCTCCGACGCCATCCTG
CGCAAGACCGGCTCGCTGACCCTCGCCCGCAAGATCCCGATCGTCGGCGGCATGCTGCTGTCGATGGCGATCATCGGCTG
CAACTATGTCGACGGCCAGGCGCTGGTGGTCGGCCTGATGGCGCTCGCCTTCTTCGGCAAGGGCATCGGCGCACTCGGCT
GGGCCGTCGTCTCCGACACCTCGCCGAAGGAAGCCGGCGGCGTCTCCGGCGGCCTGTTCAACACCTTCGGCAACCTGTCC
AGCATCACGACCCCGATCGTGATCGGCTACATCCTGTCGGCCACCGGCTCGTTCAACGGCGCGCTGGTGTTCGTCGGCCT
CAATGCGCTGGTTGCGGCGTTCGCCTATCTGTTCATCGTCGGCCGCATCCAGCGCGTCCAGCTCCGAGCCTCCTGA

Upstream 100 bases:

>100_bases
AGGATCGATCCAATATTGGCATTGATCGATACAGGCTTCGGCTTGGACCCCGGCCCTTCATCTCATCTAGGACAGTCCTT
GAGGAACGTTTAAGAGAGGT

Downstream 100 bases:

>100_bases
GCACCACGCCCCCTTGCGTGGTCTCAAACTCGAACGGCGGCCTCGTGCCGCCGTTTTTTTGCGTTGTAATAGAACCCGTA
AAGCCTGCCGCGAAGACGGT

Product: major facilitator superfamily D-glucarate permease

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MRMSAIVTTAGLRRSRVRLFIVTMLFLVTTVNYADRATLSIAGPALAKDLHLDPVAMGYVFSAFGWSYVLAQVPGGWLLD
RFGSRWVYACSIVIWSIFTMMQGWIGFLSGGAAIVALFALRFLVGLAEAPSFPANARIVAAWFPSNERGTASAFFNSGQY
FATVIFAPLMGWIAHEFGWRHVFTVMGALGIIMGLVWIRTMYGPKEHPGINEAELDYIKQGGALVDMEGAKDETRDGKTS
QGGPTWSHIGQLLSNRMMLGVYIGQYCINTLTYFFLTWFPVYLVKERGLSILQAGFVATLPALCGFIGGVLGGFISDAIL
RKTGSLTLARKIPIVGGMLLSMAIIGCNYVDGQALVVGLMALAFFGKGIGALGWAVVSDTSPKEAGGVSGGLFNTFGNLS
SITTPIVIGYILSATGSFNGALVFVGLNALVAAFAYLFIVGRIQRVQLRAS

Sequences:

>Translated_451_residues
MRMSAIVTTAGLRRSRVRLFIVTMLFLVTTVNYADRATLSIAGPALAKDLHLDPVAMGYVFSAFGWSYVLAQVPGGWLLD
RFGSRWVYACSIVIWSIFTMMQGWIGFLSGGAAIVALFALRFLVGLAEAPSFPANARIVAAWFPSNERGTASAFFNSGQY
FATVIFAPLMGWIAHEFGWRHVFTVMGALGIIMGLVWIRTMYGPKEHPGINEAELDYIKQGGALVDMEGAKDETRDGKTS
QGGPTWSHIGQLLSNRMMLGVYIGQYCINTLTYFFLTWFPVYLVKERGLSILQAGFVATLPALCGFIGGVLGGFISDAIL
RKTGSLTLARKIPIVGGMLLSMAIIGCNYVDGQALVVGLMALAFFGKGIGALGWAVVSDTSPKEAGGVSGGLFNTFGNLS
SITTPIVIGYILSATGSFNGALVFVGLNALVAAFAYLFIVGRIQRVQLRAS
>Mature_451_residues
MRMSAIVTTAGLRRSRVRLFIVTMLFLVTTVNYADRATLSIAGPALAKDLHLDPVAMGYVFSAFGWSYVLAQVPGGWLLD
RFGSRWVYACSIVIWSIFTMMQGWIGFLSGGAAIVALFALRFLVGLAEAPSFPANARIVAAWFPSNERGTASAFFNSGQY
FATVIFAPLMGWIAHEFGWRHVFTVMGALGIIMGLVWIRTMYGPKEHPGINEAELDYIKQGGALVDMEGAKDETRDGKTS
QGGPTWSHIGQLLSNRMMLGVYIGQYCINTLTYFFLTWFPVYLVKERGLSILQAGFVATLPALCGFIGGVLGGFISDAIL
RKTGSLTLARKIPIVGGMLLSMAIIGCNYVDGQALVVGLMALAFFGKGIGALGWAVVSDTSPKEAGGVSGGLFNTFGNLS
SITTPIVIGYILSATGSFNGALVFVGLNALVAAFAYLFIVGRIQRVQLRAS

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=389, Percent_Identity=27.2493573264781, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI9966811, Length=390, Percent_Identity=25.8974358974359, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI21322234, Length=395, Percent_Identity=24.5569620253165, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI6912666, Length=421, Percent_Identity=25.41567695962, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI148743791, Length=391, Percent_Identity=25.5754475703325, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4885441, Length=406, Percent_Identity=23.3990147783251, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI223718438, Length=197, Percent_Identity=28.4263959390863, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI148728191, Length=318, Percent_Identity=25.7861635220126, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI256219598, Length=308, Percent_Identity=21.7532467532468, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4503847, Length=308, Percent_Identity=21.7532467532468, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI256219483, Length=308, Percent_Identity=21.7532467532468, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI5031955, Length=282, Percent_Identity=22.6950354609929, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI256219543, Length=308, Percent_Identity=21.7532467532468, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI154350196, Length=429, Percent_Identity=22.1445221445221, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789152, Length=437, Percent_Identity=63.6155606407323, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI1789515, Length=446, Percent_Identity=57.3991031390135, Blast_Score=537, Evalue=1e-154,
Organism=Escherichia coli, GI87082320, Length=435, Percent_Identity=41.6091954022989, Blast_Score=354, Evalue=8e-99,
Organism=Escherichia coli, GI2367379, Length=431, Percent_Identity=27.6102088167053, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI2367193, Length=331, Percent_Identity=26.5861027190332, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788573, Length=469, Percent_Identity=20.682302771855, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533554, Length=439, Percent_Identity=26.6514806378132, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI115533556, Length=426, Percent_Identity=26.7605633802817, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17535049, Length=425, Percent_Identity=25.4117647058824, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17560030, Length=373, Percent_Identity=24.3967828418231, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71991448, Length=426, Percent_Identity=23.2394366197183, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71991453, Length=426, Percent_Identity=23.2394366197183, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17552542, Length=378, Percent_Identity=25.3968253968254, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17569727, Length=388, Percent_Identity=23.7113402061856, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32565914, Length=321, Percent_Identity=23.6760124610592, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=265, Percent_Identity=23.3962264150943, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25145964, Length=264, Percent_Identity=23.8636363636364, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=284, Percent_Identity=22.5352112676056, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71997452, Length=358, Percent_Identity=23.1843575418994, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550460, Length=420, Percent_Identity=27.6190476190476, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24655255, Length=377, Percent_Identity=27.5862068965517, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641682, Length=432, Percent_Identity=27.3148148148148, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24639764, Length=481, Percent_Identity=26.4033264033264, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI28573708, Length=393, Percent_Identity=29.5165394402036, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573707, Length=393, Percent_Identity=29.5165394402036, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24583789, Length=417, Percent_Identity=26.1390887290168, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24655271, Length=431, Percent_Identity=27.1461716937355, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI20130135, Length=413, Percent_Identity=27.1186440677966, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24584153, Length=424, Percent_Identity=25.7075471698113, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24654215, Length=435, Percent_Identity=25.7471264367816, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922400, Length=436, Percent_Identity=25.4587155963303, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI62484226, Length=399, Percent_Identity=27.5689223057644, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24580790, Length=396, Percent_Identity=23.989898989899, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24648416, Length=438, Percent_Identity=23.0593607305936, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356189, Length=438, Percent_Identity=23.0593607305936, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24658658, Length=407, Percent_Identity=25.3071253071253, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573299, Length=411, Percent_Identity=27.4939172749392, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI20130167, Length=464, Percent_Identity=22.8448275862069, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221474708, Length=192, Percent_Identity=30.2083333333333, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45550364, Length=436, Percent_Identity=24.5412844036697, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24658689, Length=447, Percent_Identity=25.2796420581655, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI20129235, Length=462, Percent_Identity=25.974025974026, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45552797, Length=417, Percent_Identity=25.6594724220624, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920686, Length=199, Percent_Identity=28.643216080402, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24653727, Length=418, Percent_Identity=22.7272727272727, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281361682, Length=364, Percent_Identity=22.2527472527473, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45550495, Length=372, Percent_Identity=23.3870967741935, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24658674, Length=368, Percent_Identity=25.2717391304348, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48413; Mature: 48413

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMSAIVTTAGLRRSRVRLFIVTMLFLVTTVNYADRATLSIAGPALAKDLHLDPVAMGYV
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCHHHHHHH
FSAFGWSYVLAQVPGGWLLDRFGSRWVYACSIVIWSIFTMMQGWIGFLSGGAAIVALFAL
HHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RFLVGLAEAPSFPANARIVAAWFPSNERGTASAFFNSGQYFATVIFAPLMGWIAHEFGWR
HHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCHH
HVFTVMGALGIIMGLVWIRTMYGPKEHPGINEAELDYIKQGGALVDMEGAKDETRDGKTS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCC
QGGPTWSHIGQLLSNRMMLGVYIGQYCINTLTYFFLTWFPVYLVKERGLSILQAGFVATL
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
PALCGFIGGVLGGFISDAILRKTGSLTLARKIPIVGGMLLSMAIIGCNYVDGQALVVGLM
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
ALAFFGKGIGALGWAVVSDTSPKEAGGVSGGLFNTFGNLSSITTPIVIGYILSATGSFNG
HHHHHHCCHHHHHHHEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
ALVFVGLNALVAAFAYLFIVGRIQRVQLRAS
EEEEEEHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MRMSAIVTTAGLRRSRVRLFIVTMLFLVTTVNYADRATLSIAGPALAKDLHLDPVAMGYV
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHCCCCHHHHHHH
FSAFGWSYVLAQVPGGWLLDRFGSRWVYACSIVIWSIFTMMQGWIGFLSGGAAIVALFAL
HHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RFLVGLAEAPSFPANARIVAAWFPSNERGTASAFFNSGQYFATVIFAPLMGWIAHEFGWR
HHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCHH
HVFTVMGALGIIMGLVWIRTMYGPKEHPGINEAELDYIKQGGALVDMEGAKDETRDGKTS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCC
QGGPTWSHIGQLLSNRMMLGVYIGQYCINTLTYFFLTWFPVYLVKERGLSILQAGFVATL
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
PALCGFIGGVLGGFISDAILRKTGSLTLARKIPIVGGMLLSMAIIGCNYVDGQALVVGLM
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
ALAFFGKGIGALGWAVVSDTSPKEAGGVSGGLFNTFGNLSSITTPIVIGYILSATGSFNG
HHHHHHCCHHHHHHHEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
ALVFVGLNALVAAFAYLFIVGRIQRVQLRAS
EEEEEEHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]