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The map label for this gene is cobS [H]

Identifier: 146337744

GI number: 146337744

Start: 641090

End: 642046

Strand: Direct

Name: cobS [H]

Synonym: BRADO0617

Alternate gene names: 146337744

Gene position: 641090-642046 (Clockwise)

Preceding gene: 146337742

Following gene: 146337745

Centisome position: 8.6

GC content: 64.05

Gene sequence:

>957_bases
GTGCCCGACATGAAGGTGTCGGTGCGGCAGGTGTTCGGGATCGACAGCGACCTTGAGGTGCCGGCCTTTTCCGCGACCGA
TCCGCACGTGCCGGAGGTCGATGCCGACTACCGTTTCGACCGTGCCACCACGCTCGCGATCCTGGCCGGCTTCGCCAAGA
ACCGCCGCGTCATGGTGACCGGCTACCACGGCACCGGCAAGTCGACGCATATCGAGCAGGTCGCCGCCCGCCTGAACTGG
CCGTGCGTGCGCGTCAACCTCGACAGCCACATCAGCCGCATCGACCTGGTCGGCAAGGACGCGATCGTGGTCAAGGACGG
CAAGCAGGTCACCGAGTTCCGTGACGGCATCCTACCCTGGGCCCTGCAGCACAACGTGGCGCTGGTGTTCGACGAGTACG
ACGCCGGCCGCCCGGACGTGATGTTCGTGATCCAGCGCGTGCTCGAGGTCTCGGGCCGCCTTACCCTGCTCGACCAGAAC
AAGGTCATCAAGCCGCACCCGGCGTTCCGCCTGTTCGCGACCGCCAACACCATTGGTCTCGGCGACACCTCGGGCCTGTA
TCACGGCACACAGCAGATCAACCAGGGCCAGATGGACCGCTGGTCGATCGTCACGACGCTCAACTATCTCGCGCATGACG
AGGAGGTCGAGATCGTGCTGGCCAAGGCCAAGCATTATCAGAACGCGCAGGGCCGTGACACCGTCAACAAGATGGTGCGG
CTTGCCGATCTCACGCGAAACGCCTTCGCCAATGGCGACCTGTCAACGGTGATGAGCCCGCGCACGGTGATCACCTGGGC
GGAAAACTCCGAGATCTTCGGCGACATCGGCTTCGCCTTCCGCGTCACTTTCCTGAACAAGTGCGACGAGCTCGAGCGTC
CGCTGGTCGCGGAATTCTATCAGCGCTGCTTCAATGCGGAGCTGCCGGAATCCGCCGTCAACGTCGCGTTGAGCTGA

Upstream 100 bases:

>100_bases
CAACCGCAGCCAAACCATGAAATCTGGTTTCGGGATTGCCCGGGACCTCGGAGGATGAATGACGACCGCCGCTACGACCA
ATGCGCAGGAGATGACCGGT

Downstream 100 bases:

>100_bases
TATGAGGCGTCGTCCCGGCCTCCAGCCGGGACACATATGCCGTGACCCCGATACGCCGTGACGTTTCGGCGATGCGCCGG
AGTTGGCTTCGACACGATGA

Product: aerobic cobaltochelatase subunit CobS

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPDMKVSVRQVFGIDSDLEVPAFSATDPHVPEVDADYRFDRATTLAILAGFAKNRRVMVTGYHGTGKSTHIEQVAARLNW
PCVRVNLDSHISRIDLVGKDAIVVKDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQN
KVIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLAHDEEVEIVLAKAKHYQNAQGRDTVNKMVR
LADLTRNAFANGDLSTVMSPRTVITWAENSEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAELPESAVNVALS

Sequences:

>Translated_318_residues
MPDMKVSVRQVFGIDSDLEVPAFSATDPHVPEVDADYRFDRATTLAILAGFAKNRRVMVTGYHGTGKSTHIEQVAARLNW
PCVRVNLDSHISRIDLVGKDAIVVKDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQN
KVIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLAHDEEVEIVLAKAKHYQNAQGRDTVNKMVR
LADLTRNAFANGDLSTVMSPRTVITWAENSEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAELPESAVNVALS
>Mature_317_residues
PDMKVSVRQVFGIDSDLEVPAFSATDPHVPEVDADYRFDRATTLAILAGFAKNRRVMVTGYHGTGKSTHIEQVAARLNWP
CVRVNLDSHISRIDLVGKDAIVVKDGKQVTEFRDGILPWALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQNK
VIKPHPAFRLFATANTIGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLAHDEEVEIVLAKAKHYQNAQGRDTVNKMVRL
ADLTRNAFANGDLSTVMSPRTVITWAENSEIFGDIGFAFRVTFLNKCDELERPLVAEFYQRCFNAELPESAVNVALS

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=212, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076562, Length=212, Percent_Identity=26.8867924528302, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076560, Length=212, Percent_Identity=26.8867924528302, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 35549; Mature: 35418

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDMKVSVRQVFGIDSDLEVPAFSATDPHVPEVDADYRFDRATTLAILAGFAKNRRVMVT
CCCCCEEHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
GYHGTGKSTHIEQVAARLNWPCVRVNLDSHISRIDLVGKDAIVVKDGKQVTEFRDGILPW
EECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEEECCCEEEEECCCHHHHHHCCCCCE
ALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQNKVIKPHPAFRLFATANTIGL
EECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEECCCCCEEEEEECCEECC
GDTSGLYHGTQQINQGQMDRWSIVTTLNYLAHDEEVEIVLAKAKHYQNAQGRDTVNKMVR
CCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCHHHHHHHHH
LADLTRNAFANGDLSTVMSPRTVITWAENSEIFGDIGFAFRVTFLNKCDELERPLVAEFY
HHHHHHHHCCCCCHHHHCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHH
QRCFNAELPESAVNVALS
HHHCCCCCCHHHHCEECC
>Mature Secondary Structure 
PDMKVSVRQVFGIDSDLEVPAFSATDPHVPEVDADYRFDRATTLAILAGFAKNRRVMVT
CCCCEEHHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
GYHGTGKSTHIEQVAARLNWPCVRVNLDSHISRIDLVGKDAIVVKDGKQVTEFRDGILPW
EECCCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEEECCCEEEEECCCHHHHHHCCCCCE
ALQHNVALVFDEYDAGRPDVMFVIQRVLEVSGRLTLLDQNKVIKPHPAFRLFATANTIGL
EECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCEECCCCCEEEEEECCEECC
GDTSGLYHGTQQINQGQMDRWSIVTTLNYLAHDEEVEIVLAKAKHYQNAQGRDTVNKMVR
CCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCCCHHHHHHHHH
LADLTRNAFANGDLSTVMSPRTVITWAENSEIFGDIGFAFRVTFLNKCDELERPLVAEFY
HHHHHHHHCCCCCHHHHCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHHHCCCHHHHHH
QRCFNAELPESAVNVALS
HHHCCCCCCHHHHCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]