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The map label for this gene is sucC [H]

Identifier: 146337550

GI number: 146337550

Start: 410766

End: 411962

Strand: Direct

Name: sucC [H]

Synonym: BRADO0404

Alternate gene names: 146337550

Gene position: 410766-411962 (Clockwise)

Preceding gene: 146337549

Following gene: 146337551

Centisome position: 5.51

GC content: 64.16

Gene sequence:

>1197_bases
ATGAATATTCACGAATATCAGGCCAAGGCACTGCTGCACGAGTTCGGCGTGCCGATTTCCAAGGGCGTGCCGGTTCTCCG
TCCGGAGGACGCGGATGCGGCGGCGAAGACGCTCGGCGGTCCGGTCTGGGTCGTGAAGAGCCAGATCCACGCCGGTGGCC
GTGGCAAGGGCAAGTTCAAGGAGGCCTCGGCCGGCGACAAGGGCGGCGTCCGCCTCGCCAAGTCGATCGACGAGGTCAAC
ACCTTCGCCAGGCAGATGCTCGGCGCGACCCTGGTCACGGTGCAGACCGGACCCGACGGCAAGCAGGTCAATCGCCTCTA
CATCGAGGACGGCTCGGACATCGACAAGGAGTTCTATCTGTCGCTGCTGGTCGACCGCGAAACTTCGAAGGTGGCCTTCG
TGGTGTCGACCGAGGGTGGCGTCAACATCGAGGACGTCGCGCACGAGACCCCTGAGAAGATCGTGACCTTCTCGGTCGAT
CCGGCCACCGGCGTCATGGGCCATCATGGCCGCGCCGTCGCCAAGGCGCTGAAGCTCTCCGGCGACCTCGCCAAGCAGGC
CGAGAAGCTCACCACGCAGCTCTACAATGCGTTCGTCGCCAAGGACATGGCGATGCTCGAGATCAACCCGCTGGTCGTGA
CCAAGCAGGGCCAGCTGCGCGTGCTCGACGCCAAGGTTTCGTTCGACTCCAACGCGCTGTTCAAGCACCCGGAAGTCGTC
GCGCTGCGCGACGAGACCGAGGAGGATGCCAAGGAGATCGAGGCCTCGAAGTACGACCTCAACTACGTCGCGCTCGACGG
CACCATCGGCTGCATGGTCAACGGCGCCGGCCTCGCCATGGCGACCATGGACATCATCAAGCTCTACGGCATGGAGCCCG
CCAACTTCCTCGACGTCGGCGGCGGCGCCAGCAAGGAGAAGGTCGCGGCGGCGTTCAAGATCATCACCGCCGACCCGAAC
GTGAAGGGCATCCTGGTCAACATCTTCGGCGGCATCATGAAGTGCGATGTCATCGCCGAGGGCGTGGTGGCTGCGGTCAA
GGAGGTCGGCCTCAAGGTGCCGCTGGTGGTGCGCCTCGAAGGCACCAATGTCGATCTCGGCAAGAAGATCATCAGCGAGT
CCGGTCTGAACGTGCTGCCCGCCGACAATCTCGACGACGCCGCGCAGAAGATCGTCAAGGCCGTCAAGGGAGGCTGA

Upstream 100 bases:

>100_bases
CTCCGAAGAGTTGCAGGATGCTTGGTATATGGTATACCAAGCATCCGCAAAACACTTATAGACGTCACCACCCCAGCGGG
GGTTCGGGGAGCAAGCGCTT

Downstream 100 bases:

>100_bases
GCGCCGGTTCTGGCGCTCGCTTCGTCCTCACCGCAACGCTTTTAGAGAAAGCACGATGTCCATCCTCATCGACAAAAACA
CCAAGGTCATCTGCCAGGGC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNIHEYQAKALLHEFGVPISKGVPVLRPEDADAAAKTLGGPVWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSIDEVN
TFARQMLGATLVTVQTGPDGKQVNRLYIEDGSDIDKEFYLSLLVDRETSKVAFVVSTEGGVNIEDVAHETPEKIVTFSVD
PATGVMGHHGRAVAKALKLSGDLAKQAEKLTTQLYNAFVAKDMAMLEINPLVVTKQGQLRVLDAKVSFDSNALFKHPEVV
ALRDETEEDAKEIEASKYDLNYVALDGTIGCMVNGAGLAMATMDIIKLYGMEPANFLDVGGGASKEKVAAAFKIITADPN
VKGILVNIFGGIMKCDVIAEGVVAAVKEVGLKVPLVVRLEGTNVDLGKKIISESGLNVLPADNLDDAAQKIVKAVKGG

Sequences:

>Translated_398_residues
MNIHEYQAKALLHEFGVPISKGVPVLRPEDADAAAKTLGGPVWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSIDEVN
TFARQMLGATLVTVQTGPDGKQVNRLYIEDGSDIDKEFYLSLLVDRETSKVAFVVSTEGGVNIEDVAHETPEKIVTFSVD
PATGVMGHHGRAVAKALKLSGDLAKQAEKLTTQLYNAFVAKDMAMLEINPLVVTKQGQLRVLDAKVSFDSNALFKHPEVV
ALRDETEEDAKEIEASKYDLNYVALDGTIGCMVNGAGLAMATMDIIKLYGMEPANFLDVGGGASKEKVAAAFKIITADPN
VKGILVNIFGGIMKCDVIAEGVVAAVKEVGLKVPLVVRLEGTNVDLGKKIISESGLNVLPADNLDDAAQKIVKAVKGG
>Mature_398_residues
MNIHEYQAKALLHEFGVPISKGVPVLRPEDADAAAKTLGGPVWVVKSQIHAGGRGKGKFKEASAGDKGGVRLAKSIDEVN
TFARQMLGATLVTVQTGPDGKQVNRLYIEDGSDIDKEFYLSLLVDRETSKVAFVVSTEGGVNIEDVAHETPEKIVTFSVD
PATGVMGHHGRAVAKALKLSGDLAKQAEKLTTQLYNAFVAKDMAMLEINPLVVTKQGQLRVLDAKVSFDSNALFKHPEVV
ALRDETEEDAKEIEASKYDLNYVALDGTIGCMVNGAGLAMATMDIIKLYGMEPANFLDVGGGASKEKVAAAFKIITADPN
VKGILVNIFGGIMKCDVIAEGVVAAVKEVGLKVPLVVRLEGTNVDLGKKIISESGLNVLPADNLDDAAQKIVKAVKGG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=45.5470737913486, Blast_Score=355, Evalue=4e-98,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=46.1139896373057, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=46.4088397790055, Blast_Score=316, Evalue=2e-86,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=52.6448362720403, Blast_Score=410, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=45.3164556962025, Blast_Score=345, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=46.0759493670886, Blast_Score=345, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=44.6969696969697, Blast_Score=347, Evalue=2e-96,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=49.6221662468514, Blast_Score=358, Evalue=4e-99,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=46.9072164948454, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=46.9072164948454, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=47.0437017994859, Blast_Score=345, Evalue=4e-95,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=47.0437017994859, Blast_Score=345, Evalue=4e-95,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42191; Mature: 42191

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLHEFGVPISKGVPVLRPEDADAAAKTLGGPVWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHCCCEEEEEEEECCCCCCCCCCCC
EASAGDKGGVRLAKSIDEVNTFARQMLGATLVTVQTGPDGKQVNRLYIEDGSDIDKEFYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCCCCHHHEE
SLLVDRETSKVAFVVSTEGGVNIEDVAHETPEKIVTFSVDPATGVMGHHGRAVAKALKLS
EEEEECCCCEEEEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHC
GDLAKQAEKLTTQLYNAFVAKDMAMLEINPLVVTKQGQLRVLDAKVSFDSNALFKHPEVV
CHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCEEEEEEEEECCCCCCCCCCCEE
ALRDETEEDAKEIEASKYDLNYVALDGTIGCMVNGAGLAMATMDIIKLYGMEPANFLDVG
EECCCCHHHHHHHHHCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVAAAFKIITADPNVKGILVNIFGGIMKCDVIAEGVVAAVKEVGLKVPLVVRLE
CCCCHHHHEEEEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
GTNVDLGKKIISESGLNVLPADNLDDAAQKIVKAVKGG
CCCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQAKALLHEFGVPISKGVPVLRPEDADAAAKTLGGPVWVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHCCCEEEEEEEECCCCCCCCCCCC
EASAGDKGGVRLAKSIDEVNTFARQMLGATLVTVQTGPDGKQVNRLYIEDGSDIDKEFYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCCCCHHHEE
SLLVDRETSKVAFVVSTEGGVNIEDVAHETPEKIVTFSVDPATGVMGHHGRAVAKALKLS
EEEEECCCCEEEEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHC
GDLAKQAEKLTTQLYNAFVAKDMAMLEINPLVVTKQGQLRVLDAKVSFDSNALFKHPEVV
CHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCEEEEEEEEECCCCCCCCCCCEE
ALRDETEEDAKEIEASKYDLNYVALDGTIGCMVNGAGLAMATMDIIKLYGMEPANFLDVG
EECCCCHHHHHHHHHCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVAAAFKIITADPNVKGILVNIFGGIMKCDVIAEGVVAAVKEVGLKVPLVVRLE
CCCCHHHHEEEEEEEECCCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
GTNVDLGKKIISESGLNVLPADNLDDAAQKIVKAVKGG
CCCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]