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The map label for this gene is sucD [H]

Identifier: 146337551

GI number: 146337551

Start: 412018

End: 412902

Strand: Direct

Name: sucD [H]

Synonym: BRADO0405

Alternate gene names: 146337551

Gene position: 412018-412902 (Clockwise)

Preceding gene: 146337550

Following gene: 146337552

Centisome position: 5.53

GC content: 66.78

Gene sequence:

>885_bases
ATGTCCATCCTCATCGACAAAAACACCAAGGTCATCTGCCAGGGCTTCACCGGCAAGAACGGCACCTTCCACTCCGAGGC
GGCGATCGCCTACGGCACCAAGATGGTCGGCGGCACCTCGCCGGGCAAAGGCGGCTCGACCCATCTCGGCCTGCCCGTCT
TCGACACCGTCAAGGAGGCCCGCGAGGCGACCGGCGCCGACGCCTCGGTGATCTACGTGCCGCCGCCGGGCGCCGCCGAC
GCGATCTGCGAGGCGATCGACGCCGAAGTCCCGCTGATCGTCTGCATCACCGAGGGCATCCCGGTGCTGGACATGGTCCG
CGTCAAGCGCTCGCTCGTGGGATCCAAGTCGCGCCTGATCGGGCCGAACTGCCCGGGCGTGATGACCGCCGGCGAGTGCA
AGATCGGCATCATGCCGGCCAACATCTTCAAGCCCGGCTCGGTCGGCATCGTGTCGCGCTCCGGCACCCTGACCTATGAG
GCGGTATTCCAGACCACCTCGGAAGGCCTCGGCCAGACCACCGCGGTGGGCATCGGCGGCGACCCGGTCAAAGGCACCGA
GTTCATCGACATGCTCGAGATGTTCCTGGCCGACCCCAAGACCGAGTCCATTATCATGATCGGCGAAATCGGCGGCTCGG
CCGAGGAGGACGCGGCGCAGTTCATCAAGGACGAGGCCAAGCGCGGCCGCAAGAAACCGATGGTCGGATTCATCGCCGGC
GTCACCGCGCCTCCCGGCCGTCGCATGGGCCATGCCGGCGCGATCATCTCCGGCGGCAAGGGTGATGCCGGCTCGAAGAC
CGCGGCGATGGAAGCCGCTGGTATCACTGTGTCGCCGTCGCCGGCCCGGCTCGGCAAGACTCTCGTCGAAAAGTTGAAGT
CCTGA

Upstream 100 bases:

>100_bases
GACGACGCCGCGCAGAAGATCGTCAAGGCCGTCAAGGGAGGCTGAGCGCCGGTTCTGGCGCTCGCTTCGTCCTCACCGCA
ACGCTTTTAGAGAAAGCACG

Downstream 100 bases:

>100_bases
TTCAGGGTTTAGTACTTTTCGGGGCGCATCTTTACAAAGAATAAGGTAAACCGTCCTAACCCGAGCCTGACCCCCTTTCA
CAGTGGGTCAGGCATTGCGC

Product: succinyl-CoA synthetase subunit alpha, NAD(P)-binding

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSILIDKNTKVICQGFTGKNGTFHSEAAIAYGTKMVGGTSPGKGGSTHLGLPVFDTVKEAREATGADASVIYVPPPGAAD
AICEAIDAEVPLIVCITEGIPVLDMVRVKRSLVGSKSRLIGPNCPGVMTAGECKIGIMPANIFKPGSVGIVSRSGTLTYE
AVFQTTSEGLGQTTAVGIGGDPVKGTEFIDMLEMFLADPKTESIIMIGEIGGSAEEDAAQFIKDEAKRGRKKPMVGFIAG
VTAPPGRRMGHAGAIISGGKGDAGSKTAAMEAAGITVSPSPARLGKTLVEKLKS

Sequences:

>Translated_294_residues
MSILIDKNTKVICQGFTGKNGTFHSEAAIAYGTKMVGGTSPGKGGSTHLGLPVFDTVKEAREATGADASVIYVPPPGAAD
AICEAIDAEVPLIVCITEGIPVLDMVRVKRSLVGSKSRLIGPNCPGVMTAGECKIGIMPANIFKPGSVGIVSRSGTLTYE
AVFQTTSEGLGQTTAVGIGGDPVKGTEFIDMLEMFLADPKTESIIMIGEIGGSAEEDAAQFIKDEAKRGRKKPMVGFIAG
VTAPPGRRMGHAGAIISGGKGDAGSKTAAMEAAGITVSPSPARLGKTLVEKLKS
>Mature_293_residues
SILIDKNTKVICQGFTGKNGTFHSEAAIAYGTKMVGGTSPGKGGSTHLGLPVFDTVKEAREATGADASVIYVPPPGAADA
ICEAIDAEVPLIVCITEGIPVLDMVRVKRSLVGSKSRLIGPNCPGVMTAGECKIGIMPANIFKPGSVGIVSRSGTLTYEA
VFQTTSEGLGQTTAVGIGGDPVKGTEFIDMLEMFLADPKTESIIMIGEIGGSAEEDAAQFIKDEAKRGRKKPMVGFIAGV
TAPPGRRMGHAGAIISGGKGDAGSKTAAMEAAGITVSPSPARLGKTLVEKLKS

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=292, Percent_Identity=68.8356164383562, Blast_Score=349, Evalue=2e-96,
Organism=Homo sapiens, GI38569423, Length=260, Percent_Identity=29.6153846153846, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI38569421, Length=260, Percent_Identity=29.6153846153846, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=69.2832764505119, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=64.2361111111111, Blast_Score=358, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=64.041095890411, Blast_Score=357, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI17551266, Length=258, Percent_Identity=26.7441860465116, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17557344, Length=258, Percent_Identity=26.3565891472868, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=297, Percent_Identity=55.2188552188552, Blast_Score=306, Evalue=4e-84,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=60.958904109589, Blast_Score=358, Evalue=3e-99,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=63.8225255972696, Blast_Score=345, Evalue=2e-95,
Organism=Drosophila melanogaster, GI281363477, Length=262, Percent_Identity=28.2442748091603, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281363475, Length=262, Percent_Identity=28.2442748091603, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI281363473, Length=262, Percent_Identity=28.2442748091603, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30064; Mature: 29933

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILIDKNTKVICQGFTGKNGTFHSEAAIAYGTKMVGGTSPGKGGSTHLGLPVFDTVKEA
CEEEEECCCEEEEEECCCCCCCCCCCCHHHHCCEECCCCCCCCCCCCCCCCCHHHHHHHH
REATGADASVIYVPPPGAADAICEAIDAEVPLIVCITEGIPVLDMVRVKRSLVGSKSRLI
HHHCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
GPNCPGVMTAGECKIGIMPANIFKPGSVGIVSRSGTLTYEAVFQTTSEGLGQTTAVGIGG
CCCCCCCEECCCEEEEEEECCCCCCCCEEEEECCCCEEEHHHHHHHHCCCCCEEEEECCC
DPVKGTEFIDMLEMFLADPKTESIIMIGEIGGSAEEDAAQFIKDEAKRGRKKPMVGFIAG
CCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
VTAPPGRRMGHAGAIISGGKGDAGSKTAAMEAAGITVSPSPARLGKTLVEKLKS
CCCCCCCCCCCCCEEEECCCCCCCCCHHEEEECCEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILIDKNTKVICQGFTGKNGTFHSEAAIAYGTKMVGGTSPGKGGSTHLGLPVFDTVKEA
EEEEECCCEEEEEECCCCCCCCCCCCHHHHCCEECCCCCCCCCCCCCCCCCHHHHHHHH
REATGADASVIYVPPPGAADAICEAIDAEVPLIVCITEGIPVLDMVRVKRSLVGSKSRLI
HHHCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCC
GPNCPGVMTAGECKIGIMPANIFKPGSVGIVSRSGTLTYEAVFQTTSEGLGQTTAVGIGG
CCCCCCCEECCCEEEEEEECCCCCCCCEEEEECCCCEEEHHHHHHHHCCCCCEEEEECCC
DPVKGTEFIDMLEMFLADPKTESIIMIGEIGGSAEEDAAQFIKDEAKRGRKKPMVGFIAG
CCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEC
VTAPPGRRMGHAGAIISGGKGDAGSKTAAMEAAGITVSPSPARLGKTLVEKLKS
CCCCCCCCCCCCCEEEECCCCCCCCCHHEEEECCEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]