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The map label for this gene is 146337458

Identifier: 146337458

GI number: 146337458

Start: 315081

End: 315809

Strand: Reverse

Name: 146337458

Synonym: BRADO0301

Alternate gene names: NA

Gene position: 315809-315081 (Counterclockwise)

Preceding gene: 146337462

Following gene: 146337457

Centisome position: 4.24

GC content: 70.51

Gene sequence:

>729_bases
ATGGCCGTGCTGGTGACCCGTCCCGCCCCCGACAATGAACGGACCGCCCAAGCCCTGCGCGAGCGCGGCTTCGACGTGCT
GCTGGCGCCGATGCTGCGCTTCGAGCCGGTCGCGCTGCTGGCCGATGTGGGCCAAGACGCGGCTGGAATCGTCGTGACGT
CCGCGAACGCGCTGCGCGCGGCCGCGCCGCAGTTGCGGAGCTCTGCGCTGCTGCTTCTGCCGTTGTTCGCGGTCGGCGAC
CAGACCGCGGCGGCGGCGCGCGCGGCTGGTTTCGCAAAAGTGATCTCGGCAGCCGGCGATGCGGCGGCGTTGCGCGAGGT
GATCGCGACCAGCGGTGCGATCGAGGCCAAGGCAACCCTGCTCTATCTCGCCGGCGCCGACATCTCGCGCGATCTCGCCG
CCGAGCTTGGCGCGCGCGGCTTCGAGGTCGTCACGCAGACGGTCTACCGGATGGCGCAGGTGACGAGCCTGCCGCGCGAG
GTCTGCGAGGCGTTCGCGGCGAACACGATCCAAGCCGTGCTGCATTATTCGCGGCGAAGTGCCGCGGCGTTCGTGGCGGC
GATCCGGGCCGAGGGCGTCGAAATCTCCGCGCTGGCGGTGCCGCATGGCTGCCTGTCGGCCAACGTCGCCGAGGTGCTGC
GTGACGCCGGCGCGACGCAGGTCACAATCCCAGCGCATCCGGATGAAAACGAGATGCTGGAAGGGCTAGCTCGTGCGCTC
CGGTCGTGA

Upstream 100 bases:

>100_bases
CATTATGTGTGCGCGGATCCGCCTAACATCACGAGGTCGCCAGGTGCAATCACCACGCCGTTGCAGCCCGGCCGATCCGT
ATTCGACGGGAGCATAGCAC

Downstream 100 bases:

>100_bases
ATGGCGTAAGAGGGCCTGCCCAGTCTTGCTTCAGCCAGGGAACCTCCATCATGGTCGATGAACCCGACACCGCTGCACCG
GCCTCCGATACCGGGCGGCA

Product: putative uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen III Synthase

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAVLVTRPAPDNERTAQALRERGFDVLLAPMLRFEPVALLADVGQDAAGIVVTSANALRAAAPQLRSSALLLLPLFAVGD
QTAAAARAAGFAKVISAAGDAAALREVIATSGAIEAKATLLYLAGADISRDLAAELGARGFEVVTQTVYRMAQVTSLPRE
VCEAFAANTIQAVLHYSRRSAAAFVAAIRAEGVEISALAVPHGCLSANVAEVLRDAGATQVTIPAHPDENEMLEGLARAL
RS

Sequences:

>Translated_242_residues
MAVLVTRPAPDNERTAQALRERGFDVLLAPMLRFEPVALLADVGQDAAGIVVTSANALRAAAPQLRSSALLLLPLFAVGD
QTAAAARAAGFAKVISAAGDAAALREVIATSGAIEAKATLLYLAGADISRDLAAELGARGFEVVTQTVYRMAQVTSLPRE
VCEAFAANTIQAVLHYSRRSAAAFVAAIRAEGVEISALAVPHGCLSANVAEVLRDAGATQVTIPAHPDENEMLEGLARAL
RS
>Mature_241_residues
AVLVTRPAPDNERTAQALRERGFDVLLAPMLRFEPVALLADVGQDAAGIVVTSANALRAAAPQLRSSALLLLPLFAVGDQ
TAAAARAAGFAKVISAAGDAAALREVIATSGAIEAKATLLYLAGADISRDLAAELGARGFEVVTQTVYRMAQVTSLPREV
CEAFAANTIQAVLHYSRRSAAAFVAAIRAEGVEISALAVPHGCLSANVAEVLRDAGATQVTIPAHPDENEMLEGLARALR
S

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 25035; Mature: 24904

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVTRPAPDNERTAQALRERGFDVLLAPMLRFEPVALLADVGQDAAGIVVTSANALRA
CEEEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
AAPQLRSSALLLLPLFAVGDQTAAAARAAGFAKVISAAGDAAALREVIATSGAIEAKATL
HHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHEE
LYLAGADISRDLAAELGARGFEVVTQTVYRMAQVTSLPREVCEAFAANTIQAVLHYSRRS
EEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAFVAAIRAEGVEISALAVPHGCLSANVAEVLRDAGATQVTIPAHPDENEMLEGLARAL
HHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHH
RS
CC
>Mature Secondary Structure 
AVLVTRPAPDNERTAQALRERGFDVLLAPMLRFEPVALLADVGQDAAGIVVTSANALRA
EEEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
AAPQLRSSALLLLPLFAVGDQTAAAARAAGFAKVISAAGDAAALREVIATSGAIEAKATL
HHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHEE
LYLAGADISRDLAAELGARGFEVVTQTVYRMAQVTSLPREVCEAFAANTIQAVLHYSRRS
EEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAFVAAIRAEGVEISALAVPHGCLSANVAEVLRDAGATQVTIPAHPDENEMLEGLARAL
HHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHH
RS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA