Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 146337368

GI number: 146337368

Start: 215581

End: 216186

Strand: Direct

Name: coaE [H]

Synonym: BRADO0201

Alternate gene names: 146337368

Gene position: 215581-216186 (Clockwise)

Preceding gene: 146337367

Following gene: 146337369

Centisome position: 2.89

GC content: 68.15

Gene sequence:

>606_bases
ATGCGGATGAGAGTGCTGGGGCTGACCGGCTCGATGGGCATGGGCAAGTCGACGACGGCGAAGCTGTTCGCCGAAGCCGG
CGTTCCCGTCTATGACGCCGACGCGACGGTTCATAAAGTCTACGAGGGCGAGGCCGCGCCTGCGGTCGAGGCGGCGTTTC
CCGGCACGACTGTCGACGGCAAGGTCGATCGATCGAAGCTGTCGGCCAAGGTGGTCGGCAATCCCGAGGCCATTCGCCGC
CTCGAAGCCATCGTGCACCCGATGCTGCGCTCCTATCACCAGGCGTTCCTCGATCAGGCGGAGCAGTCCGGCGTCCCCGT
TGCCGTTGTCGACGTGCCGCTGCTGTTCGAGACCGGCGGCGACAAGCGGGTGGACGCCGTCGTCGTGGTGTCGACGTCGC
CGGAGATCCAGCGTCAGCGTATCCTCGCGCGTGGCACGATGACCGAGGCGGCGCTCGATGCGCTCCTGGCGCGGCAGATG
CCCGATGCCGAGAAGCGCCAGCGGGCCGATTTCGTGGTGGATACGTCGCATGGCCTCGACCCGGTGCGCGCGCGCATCCG
CGACATCCTGGCCGAGGTCGTTAAGATGCCGCGGCGGCGCGGCTGA

Upstream 100 bases:

>100_bases
TTCACCATTCTCGGCCTGCCCCTGCTGCCGCTGCTGGCTTTCCTCCGTGAAGCGAAGCTGCTCAAATTCTGACAGCAGCC
GAGGCTGATCACTGGAGCGA

Downstream 100 bases:

>100_bases
TTCGAAGGCGCCGTTGCAGCTGCGGACCGGACCATGCGTGAGATCGTTCTCGATACCGAAACCACCGGCCTTGACGCCTT
GCGCGGTGATCGCCTGGTGG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MRMRVLGLTGSMGMGKSTTAKLFAEAGVPVYDADATVHKVYEGEAAPAVEAAFPGTTVDGKVDRSKLSAKVVGNPEAIRR
LEAIVHPMLRSYHQAFLDQAEQSGVPVAVVDVPLLFETGGDKRVDAVVVVSTSPEIQRQRILARGTMTEAALDALLARQM
PDAEKRQRADFVVDTSHGLDPVRARIRDILAEVVKMPRRRG

Sequences:

>Translated_201_residues
MRMRVLGLTGSMGMGKSTTAKLFAEAGVPVYDADATVHKVYEGEAAPAVEAAFPGTTVDGKVDRSKLSAKVVGNPEAIRR
LEAIVHPMLRSYHQAFLDQAEQSGVPVAVVDVPLLFETGGDKRVDAVVVVSTSPEIQRQRILARGTMTEAALDALLARQM
PDAEKRQRADFVVDTSHGLDPVRARIRDILAEVVKMPRRRG
>Mature_201_residues
MRMRVLGLTGSMGMGKSTTAKLFAEAGVPVYDADATVHKVYEGEAAPAVEAAFPGTTVDGKVDRSKLSAKVVGNPEAIRR
LEAIVHPMLRSYHQAFLDQAEQSGVPVAVVDVPLLFETGGDKRVDAVVVVSTSPEIQRQRILARGTMTEAALDALLARQM
PDAEKRQRADFVVDTSHGLDPVRARIRDILAEVVKMPRRRG

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI110227607, Length=179, Percent_Identity=31.8435754189944, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI191252797, Length=184, Percent_Identity=29.8913043478261, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI191252795, Length=184, Percent_Identity=29.8913043478261, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI110227605, Length=179, Percent_Identity=31.8435754189944, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI110227603, Length=179, Percent_Identity=31.8435754189944, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI110227601, Length=179, Percent_Identity=31.8435754189944, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI205277394, Length=179, Percent_Identity=31.8435754189944, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786292, Length=197, Percent_Identity=31.9796954314721, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17554944, Length=202, Percent_Identity=30.6930693069307, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=28, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644728, Length=182, Percent_Identity=28.021978021978, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24658602, Length=169, Percent_Identity=31.3609467455621, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21756; Mature: 21756

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMRVLGLTGSMGMGKSTTAKLFAEAGVPVYDADATVHKVYEGEAAPAVEAAFPGTTVDG
CCEEEEECCCCCCCCCCHHHHHHHHCCCCEEECCCHHHHHHCCCCCCCHHHCCCCCCCCC
KVDRSKLSAKVVGNPEAIRRLEAIVHPMLRSYHQAFLDQAEQSGVPVAVVDVPLLFETGG
CCCHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCC
DKRVDAVVVVSTSPEIQRQRILARGTMTEAALDALLARQMPDAEKRQRADFVVDTSHGLD
CCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCC
PVRARIRDILAEVVKMPRRRG
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRMRVLGLTGSMGMGKSTTAKLFAEAGVPVYDADATVHKVYEGEAAPAVEAAFPGTTVDG
CCEEEEECCCCCCCCCCHHHHHHHHCCCCEEECCCHHHHHHCCCCCCCHHHCCCCCCCCC
KVDRSKLSAKVVGNPEAIRRLEAIVHPMLRSYHQAFLDQAEQSGVPVAVVDVPLLFETGG
CCCHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCC
DKRVDAVVVVSTSPEIQRQRILARGTMTEAALDALLARQMPDAEKRQRADFVVDTSHGLD
CCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCC
PVRARIRDILAEVVKMPRRRG
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA