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The map label for this gene is dnaQ [H]

Identifier: 146337369

GI number: 146337369

Start: 216220

End: 216918

Strand: Direct

Name: dnaQ [H]

Synonym: BRADO0202

Alternate gene names: 146337369

Gene position: 216220-216918 (Clockwise)

Preceding gene: 146337368

Following gene: 146337371

Centisome position: 2.9

GC content: 64.95

Gene sequence:

>699_bases
ATGCGTGAGATCGTTCTCGATACCGAAACCACCGGCCTTGACGCCTTGCGCGGTGATCGCCTGGTGGAGATCGGCTGTGT
CGAGATCATCAACCGCATGCCGACAGGACAGGTGTTCCACCGCTATATCAATCCGCAACGTGACATGCCGGCGGAGGCAT
TCGCCGTCCACGGGCTGTCGACCGAGTTCCTGTCCGACAAGCCGTTGTTCCACGAGGTGGTCGAGGACTTCCTGGCGTTC
ATCGGCGATGCGCCGCTGGTGATCCACAACGCTTCGTTCGACATCGGCTTCATCAACGCCGAGCTCGACCGTGTGAAGCG
CGCGGCGATTCCCCGGGAGCGCCTGGTCGACACGTTGCTGCTGGCGCGGCGCAAGCATCCGGGCGTGTCGAACCGGCTCG
ACGATCTGTGCTCGCGCTATGCGATCGACAATTCCCGCCGCACCAAGCACGGCGCCCTGCTCGACGCGGAGCTGTTGGCC
GAAGTCTATGTCGACCTGGTCGGAGCGCGTCAGTCGCAGCTGATCCTGACGCAGGATGCGCAGGAAATCCGCATCGGCAA
TGCCGGCGATACGCCGCGCCGTCAGCGCGATGTTCCCCTGGCGCCCCGGGTGACCGAGGCCGAGCGGGAGGCGCATCGCG
CCTTCGTCGCCACCCTGGGCGACAAGCCCATCTGGATGGACTTCCTCACCGGAGCGTGA

Upstream 100 bases:

>100_bases
CCCGGTGCGCGCGCGCATCCGCGACATCCTGGCCGAGGTCGTTAAGATGCCGCGGCGGCGCGGCTGATTCGAAGGCGCCG
TTGCAGCTGCGGACCGGACC

Downstream 100 bases:

>100_bases
CCCGAACCGGGGCTCGGGTCACGTCCGTCAATCACGTCCAATAATGTCTTAACGGATCAGCTCGGGCGGCCCTGCACGCC
CTGAGCGGCGGCCTGACGTT

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MREIVLDTETTGLDALRGDRLVEIGCVEIINRMPTGQVFHRYINPQRDMPAEAFAVHGLSTEFLSDKPLFHEVVEDFLAF
IGDAPLVIHNASFDIGFINAELDRVKRAAIPRERLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYVDLVGARQSQLILTQDAQEIRIGNAGDTPRRQRDVPLAPRVTEAEREAHRAFVATLGDKPIWMDFLTGA

Sequences:

>Translated_232_residues
MREIVLDTETTGLDALRGDRLVEIGCVEIINRMPTGQVFHRYINPQRDMPAEAFAVHGLSTEFLSDKPLFHEVVEDFLAF
IGDAPLVIHNASFDIGFINAELDRVKRAAIPRERLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYVDLVGARQSQLILTQDAQEIRIGNAGDTPRRQRDVPLAPRVTEAEREAHRAFVATLGDKPIWMDFLTGA
>Mature_232_residues
MREIVLDTETTGLDALRGDRLVEIGCVEIINRMPTGQVFHRYINPQRDMPAEAFAVHGLSTEFLSDKPLFHEVVEDFLAF
IGDAPLVIHNASFDIGFINAELDRVKRAAIPRERLVDTLLLARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLA
EVYVDLVGARQSQLILTQDAQEIRIGNAGDTPRRQRDVPLAPRVTEAEREAHRAFVATLGDKPIWMDFLTGA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=240, Percent_Identity=44.1666666666667, Blast_Score=186, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26030; Mature: 26030

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVLDTETTGLDALRGDRLVEIGCVEIINRMPTGQVFHRYINPQRDMPAEAFAVHGLS
CCCEEECCCCCCCHHHCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHCCCC
TEFLSDKPLFHEVVEDFLAFIGDAPLVIHNASFDIGFINAELDRVKRAAIPRERLVDTLL
HHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEHHHHHHHHHHCCCHHHHHHHHH
LARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLAEVYVDLVGARQSQLILTQDA
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCH
QEIRIGNAGDTPRRQRDVPLAPRVTEAEREAHRAFVATLGDKPIWMDFLTGA
HHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHCCC
>Mature Secondary Structure
MREIVLDTETTGLDALRGDRLVEIGCVEIINRMPTGQVFHRYINPQRDMPAEAFAVHGLS
CCCEEECCCCCCCHHHCCCCEEEHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHCCCC
TEFLSDKPLFHEVVEDFLAFIGDAPLVIHNASFDIGFINAELDRVKRAAIPRERLVDTLL
HHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEEEEHHHHHHHHHHCCCHHHHHHHHH
LARRKHPGVSNRLDDLCSRYAIDNSRRTKHGALLDAELLAEVYVDLVGARQSQLILTQDA
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCH
QEIRIGNAGDTPRRQRDVPLAPRVTEAEREAHRAFVATLGDKPIWMDFLTGA
HHEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]