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The map label for this gene is yycF [H]

Identifier: 146337350

GI number: 146337350

Start: 194532

End: 195218

Strand: Reverse

Name: yycF [H]

Synonym: BRADO0183

Alternate gene names: 146337350

Gene position: 195218-194532 (Counterclockwise)

Preceding gene: 146337353

Following gene: 146337349

Centisome position: 2.62

GC content: 64.19

Gene sequence:

>687_bases
ATGGCCAATGCCCGCAAGATCCTGATCGTGGACGACGACACCGATCTGCGCGACACCCTGATGGAGCAGCTCTCGCTGCA
TGACGAGTTCGAAGCCCAGGCCGTCGATACCGGCGCTAAGGGGGCGAGCGCGGCAAAGGCCAATTCACCGGATCTGGTGC
TGATGGATGTGGGCCTGCCGGACACTGACGGCCGCGAGGTGGTACGTAGCTTGCGCAAGGGCGGCTTCAAGGCTCCGATC
ATCATGCTGACCGGGCACGACACCGATTCGGACACCATTCTGGGCCTCGAATCCGGCGCCAACGACTACGTCGCCAAGCC
CTTCCGCTTCGCCGTGCTGCTGGCCCGCATCCGCGCCCAGCTGCGCCAGCACGAGGCCAGCGAGGACGCCGTGTTCTCGG
TCGGCCCCTACAGCTTCCGCCCCGGCTCGAAGATGCTGACCGGCGCCAATGCCCGCAAGGTCCGCCTGACGGAAAAGGAG
ACCGCGATCTTGCGTTTCCTGTACCGCGCCGGGCAGCAGCCGGTGTCGCGCGAGACCCTGCTTCAGGAGGTCTGGGGCTA
CAATTCCGGCGTCACCACCCATACCCTGGAAACGCATATTTACCGTCTGCGGCAGAAGATCGAGAAAGATGCCGCGAATC
CAGAGATTCTCGTCACCGAGGCGGGTGGCTACAAGTTGGTGCCGTGA

Upstream 100 bases:

>100_bases
CCCTACTTCAAGACGAAACAGGGCTCATGAGCCTGTTTGCCCACCGCTGCGGCGCCCCTTTATCCGGATTCTCGCCGGCG
CCCCCAAGAGGATTGTACCT

Downstream 100 bases:

>100_bases
TACGGTCGGGGATTGGCGGTTTGCCGTCTATGATATTGGTTCCATTTCGCCTTCCCCGGGCCCTCGATGTCAATCGAAGA
CGATATTGCGCTGTTGGAGC

Product: putative two-component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MANARKILIVDDDTDLRDTLMEQLSLHDEFEAQAVDTGAKGASAAKANSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPI
IMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFSVGPYSFRPGSKMLTGANARKVRLTEKE
TAILRFLYRAGQQPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP

Sequences:

>Translated_228_residues
MANARKILIVDDDTDLRDTLMEQLSLHDEFEAQAVDTGAKGASAAKANSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPI
IMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFSVGPYSFRPGSKMLTGANARKVRLTEKE
TAILRFLYRAGQQPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP
>Mature_227_residues
ANARKILIVDDDTDLRDTLMEQLSLHDEFEAQAVDTGAKGASAAKANSPDLVLMDVGLPDTDGREVVRSLRKGGFKAPII
MLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQLRQHEASEDAVFSVGPYSFRPGSKMLTGANARKVRLTEKET
AILRFLYRAGQQPVSRETLLQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=36.7256637168142, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=33.8983050847458, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=32.8828828828829, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.9557522123894, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=205, Percent_Identity=29.7560975609756, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=29.4372294372294, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=31.1111111111111, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=28.9592760180996, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=30.9012875536481, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=33.7662337662338, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=32.9113924050633, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=30.3418803418803, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=32.4074074074074, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25111; Mature: 24980

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANARKILIVDDDTDLRDTLMEQLSLHDEFEAQAVDTGAKGASAAKANSPDLVLMDVGLP
CCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCC
DTDGREVVRSLRKGGFKAPIIMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHH
LRQHEASEDAVFSVGPYSFRPGSKMLTGANARKVRLTEKETAILRFLYRAGQQPVSRETL
HHHCCCCCCCEEEECCCCCCCCCCEEECCCCEEEEECHHHHHHHHHHHHCCCCCCHHHHH
LQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEECC
>Mature Secondary Structure 
ANARKILIVDDDTDLRDTLMEQLSLHDEFEAQAVDTGAKGASAAKANSPDLVLMDVGLP
CCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCC
DTDGREVVRSLRKGGFKAPIIMLTGHDTDSDTILGLESGANDYVAKPFRFAVLLARIRAQ
CCCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHH
LRQHEASEDAVFSVGPYSFRPGSKMLTGANARKVRLTEKETAILRFLYRAGQQPVSRETL
HHHCCCCCCCEEEECCCCCCCCCCEEECCCCEEEEECHHHHHHHHHHHHCCCCCCHHHHH
LQEVWGYNSGVTTHTLETHIYRLRQKIEKDAANPEILVTEAGGYKLVP
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]