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The map label for this gene is hrcA [H]

Identifier: 146337340

GI number: 146337340

Start: 184710

End: 185798

Strand: Reverse

Name: hrcA [H]

Synonym: BRADO0172

Alternate gene names: 146337340

Gene position: 185798-184710 (Counterclockwise)

Preceding gene: 146337344

Following gene: 146337339

Centisome position: 2.49

GC content: 68.69

Gene sequence:

>1089_bases
GTGGCCCACCACGATCCGATCAACCTGATGACACCGCCGGCGGGGCTGGCCCAGCTCAACGAGCGCTCGCGCGAGATCTT
CCGGCAGATCGTCGAGAGCTATCTCGCGACCGGCGAGCCGGTCGGCTCGCGCAACATCTCGCGGCTGATCGCGGTTCCCC
TGTCGCCGGCCTCGGTGCGCAACGTGATGGCCGATCTGGAGCAGCTCGGCCTGATTTATGCGCCGCACACCTCGGCCGGC
CGGCTGCCGACCGAGGCAGGCTTGCGGTTCTTCGTCGACGCCCTGATGCAGGTCGGCGACATGACCGAAGCCGAGCGGCA
GTCGATCCAGAGCCAGCTCGCCGCAGTCGGTCGCGCCCAGTCGGTCGAGGCCGCGCTGGACGAGGCGTTGACGCGGCTGT
CGGGGCTTACCCGTGCGGCCGCCGTGGTGCTCACCGCCAAGTCCAACACCCGGCTGAAGCACATCGAGTTCGTGCGGCTG
GAACCGGAGCAGGCGCTCGTCGTCCTGGTCGGCGAGGACGGACAGGTCGAGAACCGCGTGCTGACCTTGCCGCCCGGCGT
GCCCTCGTCGGCGCTGACCGAGGCCTCCAACTTCCTCAACGCGCGGATCCGCGGCCGCACTTTGGCGGAAGCGCGGCTGG
AGCTCGAGACCGCGCTGGCGCAGGATCGCGCCGAGCTCGATCAGCTGACGCAGAAGGTGATCGCCGCCGGCGTGGCGAGC
TGGTCCGGCGGCGACAGTGACGATCGCCAGCTGATCGTACGCGGCCACGCCAATCTGCTCGAGGACCTGCATGCGCTCGA
TGACCTCGAGCGCGTCCGGCGGCTGTTCGACGATCTCGAGACCAAGCGCGGCGTCGTCGATCTGCTCGGCCGCGCCGAGA
GCGCCGAGGGCGTGCGCATCTTCATCGGCTCGGAGAACAAACTGTTCTCGCTATCCGGCTCGTCGACGATCGTTTCGCCT
TATTCCGACGCCACGGGTCGTATCGTCGGCGTGCTCGGCGTCATCGGTCCGACCCGTCTCAACTATGCCCGGGTCATTCC
GACGGTCGATTATGCCGCGCGCCTGCTCAGCCGCCTGATGGGCGGCTGA

Upstream 100 bases:

>100_bases
TAACCGGGCGCGAATCACGCCACGCGCCGCCCGCAAGATCGGCTTGCCACCGGGCCGCCGCATGGCCAAATTATATGCAG
ATGGGTGAGGAGGATATCTG

Downstream 100 bases:

>100_bases
CATCCGACATGGTTAACCCGGCGACAGCGCCGCCGGCGCGATCGTCAGGTCGTGCTTGATTTTCGTGGTTCAAAGCACGA
TATCCCGCCCGACATTCCCA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MAHHDPINLMTPPAGLAQLNERSREIFRQIVESYLATGEPVGSRNISRLIAVPLSPASVRNVMADLEQLGLIYAPHTSAG
RLPTEAGLRFFVDALMQVGDMTEAERQSIQSQLAAVGRAQSVEAALDEALTRLSGLTRAAAVVLTAKSNTRLKHIEFVRL
EPEQALVVLVGEDGQVENRVLTLPPGVPSSALTEASNFLNARIRGRTLAEARLELETALAQDRAELDQLTQKVIAAGVAS
WSGGDSDDRQLIVRGHANLLEDLHALDDLERVRRLFDDLETKRGVVDLLGRAESAEGVRIFIGSENKLFSLSGSSTIVSP
YSDATGRIVGVLGVIGPTRLNYARVIPTVDYAARLLSRLMGG

Sequences:

>Translated_362_residues
MAHHDPINLMTPPAGLAQLNERSREIFRQIVESYLATGEPVGSRNISRLIAVPLSPASVRNVMADLEQLGLIYAPHTSAG
RLPTEAGLRFFVDALMQVGDMTEAERQSIQSQLAAVGRAQSVEAALDEALTRLSGLTRAAAVVLTAKSNTRLKHIEFVRL
EPEQALVVLVGEDGQVENRVLTLPPGVPSSALTEASNFLNARIRGRTLAEARLELETALAQDRAELDQLTQKVIAAGVAS
WSGGDSDDRQLIVRGHANLLEDLHALDDLERVRRLFDDLETKRGVVDLLGRAESAEGVRIFIGSENKLFSLSGSSTIVSP
YSDATGRIVGVLGVIGPTRLNYARVIPTVDYAARLLSRLMGG
>Mature_361_residues
AHHDPINLMTPPAGLAQLNERSREIFRQIVESYLATGEPVGSRNISRLIAVPLSPASVRNVMADLEQLGLIYAPHTSAGR
LPTEAGLRFFVDALMQVGDMTEAERQSIQSQLAAVGRAQSVEAALDEALTRLSGLTRAAAVVLTAKSNTRLKHIEFVRLE
PEQALVVLVGEDGQVENRVLTLPPGVPSSALTEASNFLNARIRGRTLAEARLELETALAQDRAELDQLTQKVIAAGVASW
SGGDSDDRQLIVRGHANLLEDLHALDDLERVRRLFDDLETKRGVVDLLGRAESAEGVRIFIGSENKLFSLSGSSTIVSPY
SDATGRIVGVLGVIGPTRLNYARVIPTVDYAARLLSRLMGG

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39049; Mature: 38918

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHHDPINLMTPPAGLAQLNERSREIFRQIVESYLATGEPVGSRNISRLIAVPLSPASVR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCHHHHH
NVMADLEQLGLIYAPHTSAGRLPTEAGLRFFVDALMQVGDMTEAERQSIQSQLAAVGRAQ
HHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHH
SVEAALDEALTRLSGLTRAAAVVLTAKSNTRLKHIEFVRLEPEQALVVLVGEDGQVENRV
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCCCEEEEEECCCCCCCCEE
LTLPPGVPSSALTEASNFLNARIRGRTLAEARLELETALAQDRAELDQLTQKVIAAGVAS
EECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WSGGDSDDRQLIVRGHANLLEDLHALDDLERVRRLFDDLETKRGVVDLLGRAESAEGVRI
CCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCEEE
FIGSENKLFSLSGSSTIVSPYSDATGRIVGVLGVIGPTRLNYARVIPTVDYAARLLSRLM
EECCCCCEEEECCCCEEECCCCCCCCHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHH
GG
CC
>Mature Secondary Structure 
AHHDPINLMTPPAGLAQLNERSREIFRQIVESYLATGEPVGSRNISRLIAVPLSPASVR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCHHHHH
NVMADLEQLGLIYAPHTSAGRLPTEAGLRFFVDALMQVGDMTEAERQSIQSQLAAVGRAQ
HHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHH
SVEAALDEALTRLSGLTRAAAVVLTAKSNTRLKHIEFVRLEPEQALVVLVGEDGQVENRV
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCCCEEEEEECCCCCCCCEE
LTLPPGVPSSALTEASNFLNARIRGRTLAEARLELETALAQDRAELDQLTQKVIAAGVAS
EECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WSGGDSDDRQLIVRGHANLLEDLHALDDLERVRRLFDDLETKRGVVDLLGRAESAEGVRI
CCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCEEE
FIGSENKLFSLSGSSTIVSPYSDATGRIVGVLGVIGPTRLNYARVIPTVDYAARLLSRLM
EECCCCCEEEECCCCEEECCCCCCCCHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHH
GG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA