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The map label for this gene is trpB [H]

Identifier: 146337264

GI number: 146337264

Start: 107501

End: 108724

Strand: Reverse

Name: trpB [H]

Synonym: BRADO0091

Alternate gene names: 146337264

Gene position: 108724-107501 (Counterclockwise)

Preceding gene: 146337265

Following gene: 146337263

Centisome position: 1.46

GC content: 65.03

Gene sequence:

>1224_bases
ATGACGACAGCCATTCCCAATTCCTACCGCAGCGGTCCGGACGAGCGCGGCCATTTCGGCATCTTCGGTGGCCGCTTCGT
GGCCGAGACCCTGATGCCGCTGATCCTGGATCTCGAAAAGGCCTATGCCGACGCCAAGGCTGATCCGGCATTCCAGGGCG
AGATGAACAGTTACCGGACGCATTACGTCGGCCGTCCATCGCCGCTGTACTATGCCGAGCGTCTGACCGAGCATCTCGGC
GGCGCCAAGATCTATTTCAAGCGCGACGAGCTCAATCATACCGGCTCGCACAAGGTCAACAACGTGCTCGGCCAGATCAT
GCTGGCGCGCCGGATGGGCAAGAAGCGCATCATCGCCGAGACCGGCGCTGGTCAGCATGGCGTCGCCACCGCGACGCTGT
GCGCGCGCTTCGGGCTGGACTGCGTGGTCTATATGGGCGCCGTCGACGTGGAGCGGCAGCAGCCGAACGTGCTGCGCATG
GAGATGCTGGGCGCCAAGGTCATTCCGGTGCAGTCCGGCGCCAGGACGCTGAAGGATGCGATGAACGAGGCGCTGCGTGA
CTGGGTCACCAACGTCCACAACACATTTTATTGCATCGGCACGGTGGCCGGCCCGCATCCCTATCCCATGATGGTGCGCG
ACTTCCAGTCGGTGATCGGCCAGGAGACGCGGACGCAGATGCAGGAGGCCGAGGGCCGGCTGCCGGATTCGCTCGTGGCC
TGCATCGGCGGCGGCTCCAATGCGATGGGCCTGTTTCATCCCTTCCTCGATGATCCCTCCGTCGAGATCTTCGGCGTCGA
GGCCGCGGGCCACGGCCTGACGCAGCTGCATGCGGCGTCGATCGCGGGTGGCCGTCCAGGTGTGCTGCATGGCAACCGGA
CCTATCTGCTGATGGACGACGACGGCCAGATCGCCGAGGCGCATTCGATCTCGGCCGGCCTCGACTATCCCGGCATCGGT
CCTGAGCATTCCTGGCTGCACGAGGCCAAGCGCGTGACCTATCTGTCCGCGACCGACGACGAGGCGCTGGACGCGTTCCT
GCTGCTGTCCCGGTTGGAGGGCATCATCCCGGCGCTCGAGCCGGCGCACGCGGTGGCCAAGGTGATGCAGCTCGCGCCGA
ACAAGCCGAAGGACCATTTGATGGTCGTCAATCTGTGCGGCCGCGGCGACAAGGACGTGCCGCAGGTCGGCGAGATCCTG
CGTAAGAGGGCGAAACAGTCGTGA

Upstream 100 bases:

>100_bases
ACGTGTCATCCGGCGTCGAGCGGACGCCGGGTGTGAAGGATTGCGACATGATCCGGAATTTCATCCGCGCGGCGCGCGCC
GCTGAAGAGTTGAGCGTTCA

Downstream 100 bases:

>100_bases
CCAGCCGGATGGATGCGCGCTTCGCGCAGTTAAAGAGTGAAGGCCGTTCGGCATTCGTGACGTTCGTGATGGGCGGCGAC
CCCGATCCGGAGACGTCGCT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTTAIPNSYRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQGEMNSYRTHYVGRPSPLYYAERLTEHLG
GAKIYFKRDELNHTGSHKVNNVLGQIMLARRMGKKRIIAETGAGQHGVATATLCARFGLDCVVYMGAVDVERQQPNVLRM
EMLGAKVIPVQSGARTLKDAMNEALRDWVTNVHNTFYCIGTVAGPHPYPMMVRDFQSVIGQETRTQMQEAEGRLPDSLVA
CIGGGSNAMGLFHPFLDDPSVEIFGVEAAGHGLTQLHAASIAGGRPGVLHGNRTYLLMDDDGQIAEAHSISAGLDYPGIG
PEHSWLHEAKRVTYLSATDDEALDAFLLLSRLEGIIPALEPAHAVAKVMQLAPNKPKDHLMVVNLCGRGDKDVPQVGEIL
RKRAKQS

Sequences:

>Translated_407_residues
MTTAIPNSYRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQGEMNSYRTHYVGRPSPLYYAERLTEHLG
GAKIYFKRDELNHTGSHKVNNVLGQIMLARRMGKKRIIAETGAGQHGVATATLCARFGLDCVVYMGAVDVERQQPNVLRM
EMLGAKVIPVQSGARTLKDAMNEALRDWVTNVHNTFYCIGTVAGPHPYPMMVRDFQSVIGQETRTQMQEAEGRLPDSLVA
CIGGGSNAMGLFHPFLDDPSVEIFGVEAAGHGLTQLHAASIAGGRPGVLHGNRTYLLMDDDGQIAEAHSISAGLDYPGIG
PEHSWLHEAKRVTYLSATDDEALDAFLLLSRLEGIIPALEPAHAVAKVMQLAPNKPKDHLMVVNLCGRGDKDVPQVGEIL
RKRAKQS
>Mature_406_residues
TTAIPNSYRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQGEMNSYRTHYVGRPSPLYYAERLTEHLGG
AKIYFKRDELNHTGSHKVNNVLGQIMLARRMGKKRIIAETGAGQHGVATATLCARFGLDCVVYMGAVDVERQQPNVLRME
MLGAKVIPVQSGARTLKDAMNEALRDWVTNVHNTFYCIGTVAGPHPYPMMVRDFQSVIGQETRTQMQEAEGRLPDSLVAC
IGGGSNAMGLFHPFLDDPSVEIFGVEAAGHGLTQLHAASIAGGRPGVLHGNRTYLLMDDDGQIAEAHSISAGLDYPGIGP
EHSWLHEAKRVTYLSATDDEALDAFLLLSRLEGIIPALEPAHAVAKVMQLAPNKPKDHLMVVNLCGRGDKDVPQVGEILR
KRAKQS

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=390, Percent_Identity=52.0512820512821, Blast_Score=419, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321412, Length=386, Percent_Identity=56.4766839378238, Blast_Score=460, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44347; Mature: 44216

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTAIPNSYRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQGEMNSYRT
CCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
HYVGRPSPLYYAERLTEHLGGAKIYFKRDELNHTGSHKVNNVLGQIMLARRMGKKRIIAE
EECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
TGAGQHGVATATLCARFGLDCVVYMGAVDVERQQPNVLRMEMLGAKVIPVQSGARTLKDA
CCCCCCCHHHHHHHHHHCCCEEEEECCEECCCCCCCCHHHHHHCCEEEECCCCHHHHHHH
MNEALRDWVTNVHNTFYCIGTVAGPHPYPMMVRDFQSVIGQETRTQMQEAEGRLPDSLVA
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHH
CIGGGSNAMGLFHPFLDDPSVEIFGVEAAGHGLTQLHAASIAGGRPGVLHGNRTYLLMDD
EECCCCCCCHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEECCEEEEEECC
DGQIAEAHSISAGLDYPGIGPEHSWLHEAKRVTYLSATDDEALDAFLLLSRLEGIIPALE
CCCEEHHHHCCCCCCCCCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHCCCCC
PAHAVAKVMQLAPNKPKDHLMVVNLCGRGDKDVPQVGEILRKRAKQS
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTAIPNSYRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQGEMNSYRT
CCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
HYVGRPSPLYYAERLTEHLGGAKIYFKRDELNHTGSHKVNNVLGQIMLARRMGKKRIIAE
EECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE
TGAGQHGVATATLCARFGLDCVVYMGAVDVERQQPNVLRMEMLGAKVIPVQSGARTLKDA
CCCCCCCHHHHHHHHHHCCCEEEEECCEECCCCCCCCHHHHHHCCEEEECCCCHHHHHHH
MNEALRDWVTNVHNTFYCIGTVAGPHPYPMMVRDFQSVIGQETRTQMQEAEGRLPDSLVA
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHH
CIGGGSNAMGLFHPFLDDPSVEIFGVEAAGHGLTQLHAASIAGGRPGVLHGNRTYLLMDD
EECCCCCCCHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEECCEEEEEECC
DGQIAEAHSISAGLDYPGIGPEHSWLHEAKRVTYLSATDDEALDAFLLLSRLEGIIPALE
CCCEEHHHHCCCCCCCCCCCCCHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHCCCCC
PAHAVAKVMQLAPNKPKDHLMVVNLCGRGDKDVPQVGEILRKRAKQS
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA