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The map label for this gene is trpF [H]

Identifier: 146337265

GI number: 146337265

Start: 108721

End: 109380

Strand: Reverse

Name: trpF [H]

Synonym: BRADO0092

Alternate gene names: 146337265

Gene position: 109380-108721 (Counterclockwise)

Preceding gene: 146337266

Following gene: 146337264

Centisome position: 1.47

GC content: 65.45

Gene sequence:

>660_bases
ATGTCTCTGCTCGTCAAGATCTGCGGCCTGACTACGCCCGAAACGCTCGACGCCGCGCTTGACGCCGGTGCCGAGATGGT
TGGCTTCGTGTTCTTTCCGCCGTCGCCGCGGCACGTCGGTCTCACGGCCGCGCGGGAGCTCGGGCAGCAGGCGAAAGGAC
GCGCGCTGAAGGTGGCGCTGACGGTCGATGCCGATGACGCGACGTTCGAGAACATTGTCGAGACTTTGCGTCCGGACCTG
TTGCAACTGCATGGCCGAGAGAGCATCGCACGCATCCGCGATCTCAAGCAACGCTTCGGCCTGCCGGTCATGAAGGCGGT
TGCCGTCGCGACCTCCGCGGATCTCGCGCCGCTGGCCGGCTATGCCGATGTCTGCGACCGCATTCTGTTCGATGCACGGG
CGCCCAAGGATGCCACCCGTCCGGGTGGATTGGGGGCCACCTTCGACTGGCATGTCCTCGAAGCTCTCAAGCTGGATCGC
CCGTTCATGGTCTCCGGGGGCTTGAGTGCCGACAACGTTGCGGAGGCCGTGCGCATCACGCGCGCAGGCGGCGTCGACGT
GTCATCCGGCGTCGAGCGGACGCCGGGTGTGAAGGATTGCGACATGATCCGGAATTTCATCCGCGCGGCGCGCGCCGCTG
AAGAGTTGAGCGTTCAATGA

Upstream 100 bases:

>100_bases
CAAGCAGGGCGCCGCGTTGTAGAAGGCGCGCAGGATCGAACGGCGCTCGGAATCCGTTGGTCCAGTTAATCCTATTCGCC
CCAGAACGCGTTCTCCACTG

Downstream 100 bases:

>100_bases
CGACAGCCATTCCCAATTCCTACCGCAGCGGTCCGGACGAGCGCGGCCATTTCGGCATCTTCGGTGGCCGCTTCGTGGCC
GAGACCCTGATGCCGCTGAT

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSLLVKICGLTTPETLDAALDAGAEMVGFVFFPPSPRHVGLTAARELGQQAKGRALKVALTVDADDATFENIVETLRPDL
LQLHGRESIARIRDLKQRFGLPVMKAVAVATSADLAPLAGYADVCDRILFDARAPKDATRPGGLGATFDWHVLEALKLDR
PFMVSGGLSADNVAEAVRITRAGGVDVSSGVERTPGVKDCDMIRNFIRAARAAEELSVQ

Sequences:

>Translated_219_residues
MSLLVKICGLTTPETLDAALDAGAEMVGFVFFPPSPRHVGLTAARELGQQAKGRALKVALTVDADDATFENIVETLRPDL
LQLHGRESIARIRDLKQRFGLPVMKAVAVATSADLAPLAGYADVCDRILFDARAPKDATRPGGLGATFDWHVLEALKLDR
PFMVSGGLSADNVAEAVRITRAGGVDVSSGVERTPGVKDCDMIRNFIRAARAAEELSVQ
>Mature_218_residues
SLLVKICGLTTPETLDAALDAGAEMVGFVFFPPSPRHVGLTAARELGQQAKGRALKVALTVDADDATFENIVETLRPDLL
QLHGRESIARIRDLKQRFGLPVMKAVAVATSADLAPLAGYADVCDRILFDARAPKDATRPGGLGATFDWHVLEALKLDRP
FMVSGGLSADNVAEAVRITRAGGVDVSSGVERTPGVKDCDMIRNFIRAARAAEELSVQ

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=208, Percent_Identity=33.1730769230769, Blast_Score=84, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320210, Length=223, Percent_Identity=31.8385650224215, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23351; Mature: 23220

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLVKICGLTTPETLDAALDAGAEMVGFVFFPPSPRHVGLTAARELGQQAKGRALKVAL
CCHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEE
TVDADDATFENIVETLRPDLLQLHGRESIARIRDLKQRFGLPVMKAVAVATSADLAPLAG
EECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHCC
YADVCDRILFDARAPKDATRPGGLGATFDWHVLEALKLDRPFMVSGGLSADNVAEAVRIT
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
RAGGVDVSSGVERTPGVKDCDMIRNFIRAARAAEELSVQ
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLLVKICGLTTPETLDAALDAGAEMVGFVFFPPSPRHVGLTAARELGQQAKGRALKVAL
CHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEE
TVDADDATFENIVETLRPDLLQLHGRESIARIRDLKQRFGLPVMKAVAVATSADLAPLAG
EECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHCC
YADVCDRILFDARAPKDATRPGGLGATFDWHVLEALKLDRPFMVSGGLSADNVAEAVRIT
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
RAGGVDVSSGVERTPGVKDCDMIRNFIRAARAAEELSVQ
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA