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The map label for this gene is ybbO [C]

Identifier: 146301489

GI number: 146301489

Start: 4445693

End: 4446688

Strand: Direct

Name: ybbO [C]

Synonym: Fjoh_3748

Alternate gene names: 146301489

Gene position: 4445693-4446688 (Clockwise)

Preceding gene: 146301485

Following gene: 146301490

Centisome position: 72.92

GC content: 42.37

Gene sequence:

>996_bases
ATGGAACAGAATAATTATCACGGAAAATTACAGAAAGCCACAGGTTCGGGATTTGACGCAAAATCTACCTCAAAGGAAAT
TATAAAAGGAATTGACCTTACAGGGAAAACTGCCATTGTAACGGGCGGGAATACAGGCATTGGCCTGGAAACGGCCAAAA
CACTTGCGGCGGCAGGGGCAACGGTCATTGTACCGGCCAGAGATGCAGAGAAAGCGAAAAGAAATCTCGAGGGAACTCCA
AATGTAATAATAGAAAACATGGATTTAATGAATCCCGGTTCTCTTGATGCTTTTGCTGAAAAGTATCTGCATTCAGAAAG
ACCGCTTGATCTGCTCATTAACAATGCAGGGATTATGTGGGTGCCGCTGCGCAGGGATTCCCGAGGCTATGAATCACAAT
TAGCCACCAATTATCTGGCACTGTTTCAGCTTACGGCAAGATTATGGCCTGCACTAAAAAAAGCTGATGGCGCCAGAGTC
GTCAATGTTTCTTCAGGAGGGCATCAATTTTCAGATTTTAATTTTCAAGATCCTAATTTTCTAAATCGGGAGTATGAGAC
CTTACAGGCCTATGGACAGTCAAAAACAGCGGTGAATCTCTTTTCTATGGAATTAGACACGCGTGCAAAAAAGTATAATG
TGAGAAGTTATTGCTTATGTCCGGGCGCTGTTGGGCAAACAGAATTAGCTCGAGAAGCGCCAGCTGATTTGTTCCAAAAA
CTCGGTTACAGTGATGCTGAAGGAAATATACTGCCGGAAGTAGCCGCGTCATTAAAAACGATCCCGCAAGGTGCAGCCAC
AACCCTTTGGGCTGCGACAAGCAAATCGCTTAACAATATTGGCGGTGTGTATTGTGAAAACGCAGATATAGCATCTTTAA
ATTCAAATGAAAAAATTATTGGAGGTGTTGCACCTTATTCATTAGATGAAAAAAATGCAAAACGTTTATGGAAATTAAGC
CAGGAAATGACCGGAATACATTTCGATCTTAGTTAA

Upstream 100 bases:

>100_bases
GTTTTGGACGTTTAAACAAACCATATTAAGACGTTTAAACAAAGTGGCTGCTTGTTTCATCCTCTAATTTTGTCCTGTTA
AAATAATTTAAATTAAAAAA

Downstream 100 bases:

>100_bases
TATTTGTATCTTTATACCGCACAAGCAATTATGGATTATCAGGTCAATTACATACACCCAGACATCAAACTTTCCAATTA
CAGCGGCAAGCTGTTTAAAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEQNNYHGKLQKATGSGFDAKSTSKEIIKGIDLTGKTAIVTGGNTGIGLETAKTLAAAGATVIVPARDAEKAKRNLEGTP
NVIIENMDLMNPGSLDAFAEKYLHSERPLDLLINNAGIMWVPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARV
VNVSSGGHQFSDFNFQDPNFLNREYETLQAYGQSKTAVNLFSMELDTRAKKYNVRSYCLCPGAVGQTELAREAPADLFQK
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKIIGGVAPYSLDEKNAKRLWKLS
QEMTGIHFDLS

Sequences:

>Translated_331_residues
MEQNNYHGKLQKATGSGFDAKSTSKEIIKGIDLTGKTAIVTGGNTGIGLETAKTLAAAGATVIVPARDAEKAKRNLEGTP
NVIIENMDLMNPGSLDAFAEKYLHSERPLDLLINNAGIMWVPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARV
VNVSSGGHQFSDFNFQDPNFLNREYETLQAYGQSKTAVNLFSMELDTRAKKYNVRSYCLCPGAVGQTELAREAPADLFQK
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKIIGGVAPYSLDEKNAKRLWKLS
QEMTGIHFDLS
>Mature_331_residues
MEQNNYHGKLQKATGSGFDAKSTSKEIIKGIDLTGKTAIVTGGNTGIGLETAKTLAAAGATVIVPARDAEKAKRNLEGTP
NVIIENMDLMNPGSLDAFAEKYLHSERPLDLLINNAGIMWVPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARV
VNVSSGGHQFSDFNFQDPNFLNREYETLQAYGQSKTAVNLFSMELDTRAKKYNVRSYCLCPGAVGQTELAREAPADLFQK
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKIIGGVAPYSLDEKNAKRLWKLS
QEMTGIHFDLS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI186928839, Length=306, Percent_Identity=34.640522875817, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI166795268, Length=305, Percent_Identity=33.4426229508197, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI225579078, Length=300, Percent_Identity=33.6666666666667, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI7706523, Length=324, Percent_Identity=31.7901234567901, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI10190746, Length=313, Percent_Identity=32.2683706070287, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI193804850, Length=304, Percent_Identity=33.2236842105263, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI146231950, Length=305, Percent_Identity=31.8032786885246, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI19923931, Length=261, Percent_Identity=30.6513409961686, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI4504503, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193207620, Length=325, Percent_Identity=28.9230769230769, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71992402, Length=315, Percent_Identity=31.1111111111111, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17532805, Length=331, Percent_Identity=29.607250755287, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17535059, Length=321, Percent_Identity=31.1526479750779, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17505416, Length=319, Percent_Identity=28.8401253918495, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17558006, Length=310, Percent_Identity=31.2903225806452, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17532791, Length=334, Percent_Identity=27.8443113772455, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32565532, Length=233, Percent_Identity=30.4721030042918, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=228, Percent_Identity=30.7017543859649, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI72001364, Length=204, Percent_Identity=31.8627450980392, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324820, Length=230, Percent_Identity=31.7391304347826, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324148, Length=199, Percent_Identity=32.1608040201005, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=204, Percent_Identity=27.4509803921569, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076371, Length=262, Percent_Identity=38.1679389312977, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI28573296, Length=300, Percent_Identity=36.6666666666667, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI19921754, Length=308, Percent_Identity=34.7402597402597, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI22024069, Length=307, Percent_Identity=36.1563517915309, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24586328, Length=322, Percent_Identity=33.5403726708075, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI20129347, Length=321, Percent_Identity=27.7258566978193, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24656154, Length=318, Percent_Identity=30.8176100628931, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI19922628, Length=318, Percent_Identity=30.8176100628931, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI45553409, Length=305, Percent_Identity=31.4754098360656, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24647948, Length=305, Percent_Identity=31.4754098360656, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24647946, Length=320, Percent_Identity=30.625, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45554248, Length=206, Percent_Identity=37.378640776699, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24640117, Length=206, Percent_Identity=37.378640776699, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24647931, Length=283, Percent_Identity=27.9151943462898, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI23397609, Length=199, Percent_Identity=31.1557788944724, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35886; Mature: 35886

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNNYHGKLQKATGSGFDAKSTSKEIIKGIDLTGKTAIVTGGNTGIGLETAKTLAAAGA
CCCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCC
TVIVPARDAEKAKRNLEGTPNVIIENMDLMNPGSLDAFAEKYLHSERPLDLLINNAGIMW
EEEEECCCHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEE
VPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARVVNVSSGGHQFSDFNFQDPNF
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
LNREYETLQAYGQSKTAVNLFSMELDTRAKKYNVRSYCLCPGAVGQTELAREAPADLFQK
CHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHCCCCEEEECCCCCCHHHHHHHCHHHHHHH
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKII
CCCCCCCCCCCHHHHHHHHHCCCCCHHEEHHHHHHHHHHCCCEEECCCCEEECCCCCEEE
GGVAPYSLDEKNAKRLWKLSQEMTGIHFDLS
ECCCCCCCCHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MEQNNYHGKLQKATGSGFDAKSTSKEIIKGIDLTGKTAIVTGGNTGIGLETAKTLAAAGA
CCCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCC
TVIVPARDAEKAKRNLEGTPNVIIENMDLMNPGSLDAFAEKYLHSERPLDLLINNAGIMW
EEEEECCCHHHHHHCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCEEE
VPLRRDSRGYESQLATNYLALFQLTARLWPALKKADGARVVNVSSGGHQFSDFNFQDPNF
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
LNREYETLQAYGQSKTAVNLFSMELDTRAKKYNVRSYCLCPGAVGQTELAREAPADLFQK
CHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHCCCCEEEECCCCCCHHHHHHHCHHHHHHH
LGYSDAEGNILPEVAASLKTIPQGAATTLWAATSKSLNNIGGVYCENADIASLNSNEKII
CCCCCCCCCCCHHHHHHHHHCCCCCHHEEHHHHHHHHHHCCCEEECCCCEEECCCCCEEE
GGVAPYSLDEKNAKRLWKLSQEMTGIHFDLS
ECCCCCCCCHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]