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The map label for this gene is cph1 [H]

Identifier: 146301485

GI number: 146301485

Start: 4441316

End: 4442824

Strand: Direct

Name: cph1 [H]

Synonym: Fjoh_3744

Alternate gene names: 146301485

Gene position: 4441316-4442824 (Clockwise)

Preceding gene: 146301484

Following gene: 146301489

Centisome position: 72.85

GC content: 40.62

Gene sequence:

>1509_bases
ATGTACCGAAATCCTGCGCTATTACAAAATATAATTGATGCTATTCCCTTTCCCATCGGGGTATATGTGGGAGATAATTT
AGAAATTGCACTGGCCAATGATGCCATGATCAAAACATGGGGCAAAGGAAATGATGTACTTGGAAAAACCTATCTGAGTG
TTGTTCCTGAAATTGAAAACCAGCAGATTCTCGATGAGGCCCTTGGCGTTTTTAAAACCGGAACAGCTTTTCATGCTGTG
GGCAGAAAAGTAGATCTGGTCATGCAGGGAATTATGACCGAATATTACTTTAATTATAGTTTTATTCCGCTTTTTGACGA
GCATGGAAAAGTCTATGGCGTGCTTAACACCGGCGCTGACATCACAGATCTGCACAAAGCAAAAGAAGAAACCCTGAAAG
CAAATGAAAAATTAACCATAGCCATAGAAAGCTCCGGGATAGGAAGTTATGAAATAGACCTTGAAACCAAAAAAATCAAG
ACTTCAGCAAATTTCAATACGATCTGTTCCATTGGAAGCGAAACAACAAATGACGATTTAATTGCAAAGCTGCACCCAGA
GGACCTTCATGCGCGCGAAAAAGCCCATCAGCAGGCGGAGGCAACGGGAAAAATATGCTATGAGGCTCGGATTTTAAATG
ATGACGGCTCCTACCGCTGGGCTAAAATCAACGGAAAGATTATCAAGGACAAAGACGGGTCTGCAAAGACCATCATTGGT
ATTGTTCAGGATATACACGAGCATAAGGAATTTCAGGAGGAACTAAAAAAGCAGGTCGCAAGCCGTACAAATGAGCTCAC
GCGTTCCAATAGTGATCTGATGCATTTTGCCAGCGTAGTGAGCCACGATCTTCGAGAGCCGCTGCGAAAAATTAAATTTT
TCAATACACTCTTACGAAATGACATAGAAGAAAATGTTAATGAAAAATCTAAAAAATACCTTCATAAAGTAAGCCAGTCT
GCCCAGAGAATGGAAAATATCATAGAGGGAATTTTGACCTATTCCACCCTTGACAAAACTTCACAGGTTATAGAAACAAT
TAATGTTAATAAGGTTATTGAAGACATAAAAATAGACCTTGAGCTCATAATAAGGGAAAAAGGTGCTATTTTAGTTACTT
CTGATCTTCCCGAGATTCAGGGAGCGCCGATTTTAATTAACCAGCTTTTCTATAACCTCCTGCAAAATGCCTTAAAATTT
TCCAAAGCGGACCAGCCTCCAAGGATTATCATAACAAGCAGCATCATCAATAGTGACGGCCAGGATTTTGTACAGATAAA
AATAAAGGATAATGGTATTGGAATTGAGGCTGAATTTGCAGAAAAGATTTTTACGGCATTTGAAAGACTGCATTCCAAAG
ACCAGTACGAGGGAAATGGCCTTGGGCTTGCCCTGTGCAGAAAGATTGCCGAAAGGCATAATGGTAAAATAACTGCAGCC
GGGGAAAAGGACAACGGCGCTGAATTTACGGTGACCCTTCCTTTACAACAAAAAGCCGATACGCTGTAG

Upstream 100 bases:

>100_bases
TATTATTGGAATTATGATACAAAATGCAGAATTCATGTAACCCTAAACTCCTAAAAAATAATAGCTTCGCCATTAAAATA
TACCAAACAAACCTAACGCT

Downstream 100 bases:

>100_bases
AAATTGAAATTTACAACCAATCCATTAGAGGAATTTTACATAGATATTAAGTACAATTGAAGACAATTGACGCCATTTAT
TGTTTAACTTTATTTAACAT

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Bacteriophytochrome cph1; Light-regulated histidine kinase 1 [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MYRNPALLQNIIDAIPFPIGVYVGDNLEIALANDAMIKTWGKGNDVLGKTYLSVVPEIENQQILDEALGVFKTGTAFHAV
GRKVDLVMQGIMTEYYFNYSFIPLFDEHGKVYGVLNTGADITDLHKAKEETLKANEKLTIAIESSGIGSYEIDLETKKIK
TSANFNTICSIGSETTNDDLIAKLHPEDLHAREKAHQQAEATGKICYEARILNDDGSYRWAKINGKIIKDKDGSAKTIIG
IVQDIHEHKEFQEELKKQVASRTNELTRSNSDLMHFASVVSHDLREPLRKIKFFNTLLRNDIEENVNEKSKKYLHKVSQS
AQRMENIIEGILTYSTLDKTSQVIETINVNKVIEDIKIDLELIIREKGAILVTSDLPEIQGAPILINQLFYNLLQNALKF
SKADQPPRIIITSSIINSDGQDFVQIKIKDNGIGIEAEFAEKIFTAFERLHSKDQYEGNGLGLALCRKIAERHNGKITAA
GEKDNGAEFTVTLPLQQKADTL

Sequences:

>Translated_502_residues
MYRNPALLQNIIDAIPFPIGVYVGDNLEIALANDAMIKTWGKGNDVLGKTYLSVVPEIENQQILDEALGVFKTGTAFHAV
GRKVDLVMQGIMTEYYFNYSFIPLFDEHGKVYGVLNTGADITDLHKAKEETLKANEKLTIAIESSGIGSYEIDLETKKIK
TSANFNTICSIGSETTNDDLIAKLHPEDLHAREKAHQQAEATGKICYEARILNDDGSYRWAKINGKIIKDKDGSAKTIIG
IVQDIHEHKEFQEELKKQVASRTNELTRSNSDLMHFASVVSHDLREPLRKIKFFNTLLRNDIEENVNEKSKKYLHKVSQS
AQRMENIIEGILTYSTLDKTSQVIETINVNKVIEDIKIDLELIIREKGAILVTSDLPEIQGAPILINQLFYNLLQNALKF
SKADQPPRIIITSSIINSDGQDFVQIKIKDNGIGIEAEFAEKIFTAFERLHSKDQYEGNGLGLALCRKIAERHNGKITAA
GEKDNGAEFTVTLPLQQKADTL
>Mature_502_residues
MYRNPALLQNIIDAIPFPIGVYVGDNLEIALANDAMIKTWGKGNDVLGKTYLSVVPEIENQQILDEALGVFKTGTAFHAV
GRKVDLVMQGIMTEYYFNYSFIPLFDEHGKVYGVLNTGADITDLHKAKEETLKANEKLTIAIESSGIGSYEIDLETKKIK
TSANFNTICSIGSETTNDDLIAKLHPEDLHAREKAHQQAEATGKICYEARILNDDGSYRWAKINGKIIKDKDGSAKTIIG
IVQDIHEHKEFQEELKKQVASRTNELTRSNSDLMHFASVVSHDLREPLRKIKFFNTLLRNDIEENVNEKSKKYLHKVSQS
AQRMENIIEGILTYSTLDKTSQVIETINVNKVIEDIKIDLELIIREKGAILVTSDLPEIQGAPILINQLFYNLLQNALKF
SKADQPPRIIITSSIINSDGQDFVQIKIKDNGIGIEAEFAEKIFTAFERLHSKDQYEGNGLGLALCRKIAERHNGKITAA
GEKDNGAEFTVTLPLQQKADTL

Specific function: Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Has also a slight blue shift

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=329, Percent_Identity=25.2279635258359, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=27.4436090225564, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=312, Percent_Identity=25, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=25.4237288135593, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=26.6375545851528, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=276, Percent_Identity=26.4492753623188, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786912, Length=118, Percent_Identity=38.135593220339, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=24.2424242424242, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=228, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=214, Percent_Identity=26.1682242990654, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=27.6150627615063, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=23.6842105263158, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR000014
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56175; Mature: 56175

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRNPALLQNIIDAIPFPIGVYVGDNLEIALANDAMIKTWGKGNDVLGKTYLSVVPEIEN
CCCCHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEEECCCCCCCHHHHHHHHCCCCCC
QQILDEALGVFKTGTAFHAVGRKVDLVMQGIMTEYYFNYSFIPLFDEHGKVYGVLNTGAD
HHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCC
ITDLHKAKEETLKANEKLTIAIESSGIGSYEIDLETKKIKTSANFNTICSIGSETTNDDL
HHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEEHHEEECCCCCCCEEECCCCCCCCCE
IAKLHPEDLHAREKAHQQAEATGKICYEARILNDDGSYRWAKINGKIIKDKDGSAKTIIG
EEEECCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCEEEECCCCCHHHHHH
IVQDIHEHKEFQEELKKQVASRTNELTRSNSDLMHFASVVSHDLREPLRKIKFFNTLLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIEENVNEKSKKYLHKVSQSAQRMENIIEGILTYSTLDKTSQVIETINVNKVIEDIKIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
ELIIREKGAILVTSDLPEIQGAPILINQLFYNLLQNALKFSKADQPPRIIITSSIINSDG
EEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCC
QDFVQIKIKDNGIGIEAEFAEKIFTAFERLHSKDQYEGNGLGLALCRKIAERHNGKITAA
CEEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEC
GEKDNGAEFTVTLPLQQKADTL
CCCCCCCEEEEEEECHHCCCCC
>Mature Secondary Structure
MYRNPALLQNIIDAIPFPIGVYVGDNLEIALANDAMIKTWGKGNDVLGKTYLSVVPEIEN
CCCCHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEEECCCCCCCHHHHHHHHCCCCCC
QQILDEALGVFKTGTAFHAVGRKVDLVMQGIMTEYYFNYSFIPLFDEHGKVYGVLNTGAD
HHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEECCCC
ITDLHKAKEETLKANEKLTIAIESSGIGSYEIDLETKKIKTSANFNTICSIGSETTNDDL
HHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEEEHHEEECCCCCCCEEECCCCCCCCCE
IAKLHPEDLHAREKAHQQAEATGKICYEARILNDDGSYRWAKINGKIIKDKDGSAKTIIG
EEEECCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCEEEECCCCCHHHHHH
IVQDIHEHKEFQEELKKQVASRTNELTRSNSDLMHFASVVSHDLREPLRKIKFFNTLLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIEENVNEKSKKYLHKVSQSAQRMENIIEGILTYSTLDKTSQVIETINVNKVIEDIKIDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCE
ELIIREKGAILVTSDLPEIQGAPILINQLFYNLLQNALKFSKADQPPRIIITSSIINSDG
EEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCC
QDFVQIKIKDNGIGIEAEFAEKIFTAFERLHSKDQYEGNGLGLALCRKIAERHNGKITAA
CEEEEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEC
GEKDNGAEFTVTLPLQQKADTL
CCCCCCCEEEEEEECHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9109482; 9278513; 10828948 [H]