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The map label for this gene is exsA [H]

Identifier: 146301490

GI number: 146301490

Start: 4446719

End: 4447537

Strand: Direct

Name: exsA [H]

Synonym: Fjoh_3749

Alternate gene names: 146301490

Gene position: 4446719-4447537 (Clockwise)

Preceding gene: 146301489

Following gene: 146301491

Centisome position: 72.93

GC content: 38.46

Gene sequence:

>819_bases
ATGGATTATCAGGTCAATTACATACACCCAGACATCAAACTTTCCAATTACAGCGGCAAGCTGTTTAAAACGGAAGCCGC
CTTTAATGACCATCTGCTTGTGTGGTTAATTTCAGGTGAAACCAAAATTATCCAGGCAGATCAAACTTTTGTATTTGGCC
CGGGCAGTACTTTTTTAATTCCCAGAAACCAATTGGCGGCAATCATTAATATTCCAAAAGATGGACTGCCCCACAAAGCA
GCTGCGATGCATCTATCGGCTGACAGGCTTCGTGAATTTTACGATCACCAAAATGCAAAATTAAAAACTGCCGTACCAAA
AATTTTCAGTTTCCATAAACATCCTCTGCTGGAAAGCTGTCTGGCTTCGCTGATTCCTTATTTTGACATGCAGGACAACT
TTCCTGAGAATATCGCTTCATTGAAAATCACTGAAGCAATTTCAATTCTTAGAAACATTGATCCCGCTATTGATGCTGTA
CTGGCCAGCTTTGAAGAACCTGATAAAATTGATTTAACTGCTTTTATGGAGAAAAACTTTATGTTTAATATGCCTTTGGA
AAAATTTGGCTATTTAACAGGCCGGAGTCTTACCACTTTTAAGCGCGATTTCCATAAGGCTTTCAATACTACACCGCAAC
GCTGGCTAACCCAAAAAAGATTAGAATTAGCCCATTACCAGCTTGCCGAAAATAATAAAAACCCTGTTGATATCTTTTAC
GAGATAGGATTTGAGAATTTATCGCATTTTTCATTTGCATTCAAAAAACAATTTGGCTACCCGCCAACTCAACTGAAAAA
AAGCAATACGAACTGTTAG

Upstream 100 bases:

>100_bases
TGAAAAAAATGCAAAACGTTTATGGAAATTAAGCCAGGAAATGACCGGAATACATTTCGATCTTAGTTAATATTTGTATC
TTTATACCGCACAAGCAATT

Downstream 100 bases:

>100_bases
CGCTCTTTCTGAGTGCCTTTTTTAAAAACGATACAAAAAGCTATGGCAAATTTACAATTAATTTGCTGTTTCAAAATTTG
CGGCAGGATCGCGGCGCATA

Product: helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MDYQVNYIHPDIKLSNYSGKLFKTEAAFNDHLLVWLISGETKIIQADQTFVFGPGSTFLIPRNQLAAIINIPKDGLPHKA
AAMHLSADRLREFYDHQNAKLKTAVPKIFSFHKHPLLESCLASLIPYFDMQDNFPENIASLKITEAISILRNIDPAIDAV
LASFEEPDKIDLTAFMEKNFMFNMPLEKFGYLTGRSLTTFKRDFHKAFNTTPQRWLTQKRLELAHYQLAENNKNPVDIFY
EIGFENLSHFSFAFKKQFGYPPTQLKKSNTNC

Sequences:

>Translated_272_residues
MDYQVNYIHPDIKLSNYSGKLFKTEAAFNDHLLVWLISGETKIIQADQTFVFGPGSTFLIPRNQLAAIINIPKDGLPHKA
AAMHLSADRLREFYDHQNAKLKTAVPKIFSFHKHPLLESCLASLIPYFDMQDNFPENIASLKITEAISILRNIDPAIDAV
LASFEEPDKIDLTAFMEKNFMFNMPLEKFGYLTGRSLTTFKRDFHKAFNTTPQRWLTQKRLELAHYQLAENNKNPVDIFY
EIGFENLSHFSFAFKKQFGYPPTQLKKSNTNC
>Mature_272_residues
MDYQVNYIHPDIKLSNYSGKLFKTEAAFNDHLLVWLISGETKIIQADQTFVFGPGSTFLIPRNQLAAIINIPKDGLPHKA
AAMHLSADRLREFYDHQNAKLKTAVPKIFSFHKHPLLESCLASLIPYFDMQDNFPENIASLKITEAISILRNIDPAIDAV
LASFEEPDKIDLTAFMEKNFMFNMPLEKFGYLTGRSLTTFKRDFHKAFNTTPQRWLTQKRLELAHYQLAENNKNPVDIFY
EIGFENLSHFSFAFKKQFGYPPTQLKKSNTNC

Specific function: Appears to be required for induction of exoenzyme S synthesis above a low basal level [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 31303; Mature: 31303

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYQVNYIHPDIKLSNYSGKLFKTEAAFNDHLLVWLISGETKIIQADQTFVFGPGSTFLI
CCCEEEEECCCEEEECCCCCEEEECCCCCCCEEEEEECCCEEEEEECCEEEECCCCEEEE
PRNQLAAIINIPKDGLPHKAAAMHLSADRLREFYDHQNAKLKTAVPKIFSFHKHPLLESC
ECCCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHCCCCEEHHHHHHHHHHCCCHHHHHH
LASLIPYFDMQDNFPENIASLKITEAISILRNIDPAIDAVLASFEEPDKIDLTAFMEKNF
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEHEEEECCCC
MFNMPLEKFGYLTGRSLTTFKRDFHKAFNTTPQRWLTQKRLELAHYQLAENNKNPVDIFY
EEECCHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
EIGFENLSHFSFAFKKQFGYPPTQLKKSNTNC
EECCCCHHHHHHHHHHHCCCCHHHHCCCCCCC
>Mature Secondary Structure
MDYQVNYIHPDIKLSNYSGKLFKTEAAFNDHLLVWLISGETKIIQADQTFVFGPGSTFLI
CCCEEEEECCCEEEECCCCCEEEECCCCCCCEEEEEECCCEEEEEECCEEEECCCCEEEE
PRNQLAAIINIPKDGLPHKAAAMHLSADRLREFYDHQNAKLKTAVPKIFSFHKHPLLESC
ECCCEEEEEECCCCCCCCHHHHHHCCHHHHHHHHHCCCCEEHHHHHHHHHHCCCHHHHHH
LASLIPYFDMQDNFPENIASLKITEAISILRNIDPAIDAVLASFEEPDKIDLTAFMEKNF
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEHEEEECCCC
MFNMPLEKFGYLTGRSLTTFKRDFHKAFNTTPQRWLTQKRLELAHYQLAENNKNPVDIFY
EEECCHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
EIGFENLSHFSFAFKKQFGYPPTQLKKSNTNC
EECCCCHHHHHHHHHHHCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655713; 10984043 [H]