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The map label for this gene is atsA [H]

Identifier: 146300888

GI number: 146300888

Start: 3733139

End: 3735511

Strand: Reverse

Name: atsA [H]

Synonym: Fjoh_3143

Alternate gene names: 146300888

Gene position: 3735511-3733139 (Counterclockwise)

Preceding gene: 146300889

Following gene: 146300887

Centisome position: 61.27

GC content: 40.96

Gene sequence:

>2373_bases
ATGAAGTCTCTTATTAGTCCAAAACTGCTGTTAATTTTAGCTGTATTTCTTTTCAGCTGCAACCAATCTCAAAAAACAGA
TTCTGTTACAGAAAAAACAGATTCAGGAGAATTAGACCGAACCATACTGCCAATTCCAGAACCTCCATTTGGCGGAAAAA
TTGGAGAAACGTACAAAGACTCCAAAGAAGAATGGCCAAAACTCGTTACACCTCCGCAGGGAGCGCCAAACGTAATTATT
ATTCTTTTAGACGATGTTGGTTTTGGGCAGGTAAGTACTTTCGGAGGACCAGTTCCTACGCCAGAATTAGATAAACTGGC
AGCAAACGGTTTAAAATACAATCGATTTCATACTACTGCAATCTGCGGGCCTTCGCGAGCGGCATTATTGACAGGAAGAA
ATCATCATAATGCAGGTTCTGGTTTCTTAGCCGAATGGGCAACAGGATATCCGAGTTACAATTGTATGATTCCAAAAACA
ACGGCAACATCTGGAAGAATTTTAAAAGGAAACGGATACAGTACGAGCTGGTTTGGAAAAAATCACAATACGCCAGACTG
GGAAACTTCTGTTACCGGTCCTTTCGATCGTTGGCCTACAGGTTTAGGGTTTGATTACTTTTATGGATTTAATGCTGGAG
AAACACATCAGTATTATCCGGTTCTTTTTGAAAATACCAAAGCCGTAGAACCAGATAAATCTCCAGAGCAAGGTTATCAT
TTTATGACCGATATGACCGATAGAGCCATTAACTGGCTGGAATACAGTAAATCGGTTGCGCCTCAAAAACCGGTTATGCT
GTATTTTGCTCCCGGAGCTGCGCACGCACCGCATCATGCACCAAAAGAATGGAGAGATAAATTTAAAGGACAGTTTGATA
AAGGCTGGGATGTTGTGAGACAGGAAACCTATGAACGTCAACTGAAAATGGGAATTATTCCGCCTAAAACAAAATTAACT
CCAAGACCAGACTGGGTTACACCATGGGATAAACTTTCGGCAGATCAGAAAAAATTGTTTGCGCGTTTGATGGAAAACTA
TGCAGGATATCTTTCGTTTGCTGATCATGAAACAGGACGTCTTTTAGAAGCCATAAGCAAACTTCCGGATGCCGATAATA
CGTTGATATTTTATATTGTGGGAGATAACGGTGCAAGTTCTGAAGGAGGAATGGAAGGAACAGTTAATGAAATAAAAGCA
TTAAGCGGTATTTCAACTCCTTTGGCAGACAACTTAAAACATCTTGACGAAATTGGAGGCCCTAATACCGAGCCGCATTA
TCCTGTAGGCTGGGCTTGGGCAGGAAATGCTCCTTTTCAATGGGTGAAACAAGTAGCGTCTCACTTTGGCGGAAGCCGAA
ATCCAATGGTAGTAAGCTGGCCAAAAGTAATTAAAGATAAAGGCGGTATGCGCAGTCAGTTTGTGCATTTAATAGACGTG
CTTCCTACGATTTTAGATGCTTCTCATTTACCATCGCCAAAAAGCGTTGATGGTGTTGAACAGAAACCTATGGACGGGGT
TTCGTTCTTGTCGACTTTTGCAGATAAAAACGCTAAACCTGTTAGAACGAGACAATATTTTGAAATTTTCAGTAACCGGG
CTATATATGATAATGGATGGGTAGCGGCAACACAGCATACTTTTCCGTGGAGACAGGATTTTGCACCCGGAAATTGGGAT
AAAGACAAATGGGAACTTTATAATATTGATGAAGATTACAGCGAATCTGTTGATTTGGCTAAAAAATATCCCGAAAAGCT
GAAAGAATTGAAAGCAATTTTTGATGAAGAAGCCAAGAAATACAATGTTTATCCGCTGGATGACAGAGGTACAGGAAGAT
TAATTTCGCCAAAACCTACGCCGTCAGATCCTAAACGCAAACACTTTACGTTCTACGCAGGCGCAACCAGACTGGCAGAA
ACAGCTTCTCCAAATACCAAAAATAAATCGCACAGCATTACAGCCGAAATTGAGTTGAAATCTAAATCAGACAGCGGTAT
TATTGTGGCTTCTGGCGGAAGTTCGGCTGGATTTGCTCTGTATGTGCAGAACGGAAAACTGGTTTATCATTATAATTATT
TTGATGATGCCCGTTATGTCATTACGTCAAAAGAATCGCTTCCGGTTGGAAAAAGCACCGTACGATTTGATTTTGCTTAT
GATGGCGGAGGAACTGGAAAAGGTGGCACCGGAAAACTGTATATCAATGATAAATTAGTTGGTGAAGGCCGAATTGATAA
AACCGTCGCAGCCCGTTTCGGAATCGATACTTTCGGAATTGGTGAAGATTCAGGATCGCCAGTTGCAAATTCGTATAAGC
TTCCATTTAAGTTTACGGGAATTATTGATAAGGTCGAGATTGACTTGAAATAA

Upstream 100 bases:

>100_bases
GACTTAAAAAACTTTGTTGCAAGTTATAATCTGCAACATCATTAAAAAGTTTTGTAATACGCAGGTTTGTAAATTAGTGG
GTATCACTAAAACTAGAAAT

Downstream 100 bases:

>100_bases
TTGTGAATTAAAAATTTTAGCATAAATCAAAGAATTATGAGAAAGTATATTGTTTTATTAGCTTTAGCTTTAGTTGCTGA
AATGAGCGCACAGCAAAACT

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 790; Mature: 790

Protein sequence:

>790_residues
MKSLISPKLLLILAVFLFSCNQSQKTDSVTEKTDSGELDRTILPIPEPPFGGKIGETYKDSKEEWPKLVTPPQGAPNVII
ILLDDVGFGQVSTFGGPVPTPELDKLAANGLKYNRFHTTAICGPSRAALLTGRNHHNAGSGFLAEWATGYPSYNCMIPKT
TATSGRILKGNGYSTSWFGKNHNTPDWETSVTGPFDRWPTGLGFDYFYGFNAGETHQYYPVLFENTKAVEPDKSPEQGYH
FMTDMTDRAINWLEYSKSVAPQKPVMLYFAPGAAHAPHHAPKEWRDKFKGQFDKGWDVVRQETYERQLKMGIIPPKTKLT
PRPDWVTPWDKLSADQKKLFARLMENYAGYLSFADHETGRLLEAISKLPDADNTLIFYIVGDNGASSEGGMEGTVNEIKA
LSGISTPLADNLKHLDEIGGPNTEPHYPVGWAWAGNAPFQWVKQVASHFGGSRNPMVVSWPKVIKDKGGMRSQFVHLIDV
LPTILDASHLPSPKSVDGVEQKPMDGVSFLSTFADKNAKPVRTRQYFEIFSNRAIYDNGWVAATQHTFPWRQDFAPGNWD
KDKWELYNIDEDYSESVDLAKKYPEKLKELKAIFDEEAKKYNVYPLDDRGTGRLISPKPTPSDPKRKHFTFYAGATRLAE
TASPNTKNKSHSITAEIELKSKSDSGIIVASGGSSAGFALYVQNGKLVYHYNYFDDARYVITSKESLPVGKSTVRFDFAY
DGGGTGKGGTGKLYINDKLVGEGRIDKTVAARFGIDTFGIGEDSGSPVANSYKLPFKFTGIIDKVEIDLK

Sequences:

>Translated_790_residues
MKSLISPKLLLILAVFLFSCNQSQKTDSVTEKTDSGELDRTILPIPEPPFGGKIGETYKDSKEEWPKLVTPPQGAPNVII
ILLDDVGFGQVSTFGGPVPTPELDKLAANGLKYNRFHTTAICGPSRAALLTGRNHHNAGSGFLAEWATGYPSYNCMIPKT
TATSGRILKGNGYSTSWFGKNHNTPDWETSVTGPFDRWPTGLGFDYFYGFNAGETHQYYPVLFENTKAVEPDKSPEQGYH
FMTDMTDRAINWLEYSKSVAPQKPVMLYFAPGAAHAPHHAPKEWRDKFKGQFDKGWDVVRQETYERQLKMGIIPPKTKLT
PRPDWVTPWDKLSADQKKLFARLMENYAGYLSFADHETGRLLEAISKLPDADNTLIFYIVGDNGASSEGGMEGTVNEIKA
LSGISTPLADNLKHLDEIGGPNTEPHYPVGWAWAGNAPFQWVKQVASHFGGSRNPMVVSWPKVIKDKGGMRSQFVHLIDV
LPTILDASHLPSPKSVDGVEQKPMDGVSFLSTFADKNAKPVRTRQYFEIFSNRAIYDNGWVAATQHTFPWRQDFAPGNWD
KDKWELYNIDEDYSESVDLAKKYPEKLKELKAIFDEEAKKYNVYPLDDRGTGRLISPKPTPSDPKRKHFTFYAGATRLAE
TASPNTKNKSHSITAEIELKSKSDSGIIVASGGSSAGFALYVQNGKLVYHYNYFDDARYVITSKESLPVGKSTVRFDFAY
DGGGTGKGGTGKLYINDKLVGEGRIDKTVAARFGIDTFGIGEDSGSPVANSYKLPFKFTGIIDKVEIDLK
>Mature_790_residues
MKSLISPKLLLILAVFLFSCNQSQKTDSVTEKTDSGELDRTILPIPEPPFGGKIGETYKDSKEEWPKLVTPPQGAPNVII
ILLDDVGFGQVSTFGGPVPTPELDKLAANGLKYNRFHTTAICGPSRAALLTGRNHHNAGSGFLAEWATGYPSYNCMIPKT
TATSGRILKGNGYSTSWFGKNHNTPDWETSVTGPFDRWPTGLGFDYFYGFNAGETHQYYPVLFENTKAVEPDKSPEQGYH
FMTDMTDRAINWLEYSKSVAPQKPVMLYFAPGAAHAPHHAPKEWRDKFKGQFDKGWDVVRQETYERQLKMGIIPPKTKLT
PRPDWVTPWDKLSADQKKLFARLMENYAGYLSFADHETGRLLEAISKLPDADNTLIFYIVGDNGASSEGGMEGTVNEIKA
LSGISTPLADNLKHLDEIGGPNTEPHYPVGWAWAGNAPFQWVKQVASHFGGSRNPMVVSWPKVIKDKGGMRSQFVHLIDV
LPTILDASHLPSPKSVDGVEQKPMDGVSFLSTFADKNAKPVRTRQYFEIFSNRAIYDNGWVAATQHTFPWRQDFAPGNWD
KDKWELYNIDEDYSESVDLAKKYPEKLKELKAIFDEEAKKYNVYPLDDRGTGRLISPKPTPSDPKRKHFTFYAGATRLAE
TASPNTKNKSHSITAEIELKSKSDSGIIVASGGSSAGFALYVQNGKLVYHYNYFDDARYVITSKESLPVGKSTVRFDFAY
DGGGTGKGGTGKLYINDKLVGEGRIDKTVAARFGIDTFGIGEDSGSPVANSYKLPFKFTGIIDKVEIDLK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=227, Percent_Identity=31.2775330396476, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI38569407, Length=233, Percent_Identity=28.755364806867, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI38569405, Length=233, Percent_Identity=28.755364806867, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI71852586, Length=168, Percent_Identity=32.7380952380952, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI71852584, Length=184, Percent_Identity=32.0652173913043, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI4503899, Length=459, Percent_Identity=24.8366013071895, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI59797060, Length=220, Percent_Identity=30, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI53831991, Length=143, Percent_Identity=34.965034965035, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI157266309, Length=142, Percent_Identity=33.8028169014084, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI146229331, Length=135, Percent_Identity=36.2962962962963, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI146229329, Length=135, Percent_Identity=36.2962962962963, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI6005990, Length=135, Percent_Identity=36.2962962962963, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI146229324, Length=135, Percent_Identity=36.2962962962963, Blast_Score=70, Evalue=1e-11,
Organism=Homo sapiens, GI31742482, Length=140, Percent_Identity=31.4285714285714, Blast_Score=68, Evalue=4e-11,
Organism=Homo sapiens, GI58743319, Length=142, Percent_Identity=31.6901408450704, Blast_Score=67, Evalue=8e-11,
Organism=Escherichia coli, GI87081924, Length=488, Percent_Identity=24.7950819672131, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790233, Length=160, Percent_Identity=31.875, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17559078, Length=238, Percent_Identity=26.0504201680672, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666109, Length=343, Percent_Identity=26.530612244898, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281366397, Length=238, Percent_Identity=31.0924369747899, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281366395, Length=238, Percent_Identity=31.0924369747899, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666163, Length=238, Percent_Identity=31.0924369747899, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666175, Length=230, Percent_Identity=30, Blast_Score=77, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281363223, Length=459, Percent_Identity=24.400871459695, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 87655; Mature: 87655

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLISPKLLLILAVFLFSCNQSQKTDSVTEKTDSGELDRTILPIPEPPFGGKIGETYKD
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCEEECCCCCCCCCCCCCCHHC
SKEEWPKLVTPPQGAPNVIIILLDDVGFGQVSTFGGPVPTPELDKLAANGLKYNRFHTTA
CHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCEEECEEEEEE
ICGPSRAALLTGRNHHNAGSGFLAEWATGYPSYNCMIPKTTATSGRILKGNGYSTSWFGK
EECCCCEEEEECCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCCCCCC
NHNTPDWETSVTGPFDRWPTGLGFDYFYGFNAGETHQYYPVLFENTKAVEPDKSPEQGYH
CCCCCCCCCCCCCCHHHCCCCCCCHHEECCCCCCCCEEEEEEECCCCCCCCCCCHHHCCE
FMTDMTDRAINWLEYSKSVAPQKPVMLYFAPGAAHAPHHAPKEWRDKFKGQFDKGWDVVR
EHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCHHHHH
QETYERQLKMGIIPPKTKLTPRPDWVTPWDKLSADQKKLFARLMENYAGYLSFADHETGR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCEEEECCCCHHH
LLEAISKLPDADNTLIFYIVGDNGASSEGGMEGTVNEIKALSGISTPLADNLKHLDEIGG
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
PNTEPHYPVGWAWAGNAPFQWVKQVASHFGGSRNPMVVSWPKVIKDKGGMRSQFVHLIDV
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECHHHHHCCCCHHHHHHHHHHH
LPTILDASHLPSPKSVDGVEQKPMDGVSFLSTFADKNAKPVRTRQYFEIFSNRAIYDNGW
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCE
VAATQHTFPWRQDFAPGNWDKDKWELYNIDEDYSESVDLAKKYPEKLKELKAIFDEEAKK
EEEECCCCCCHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YNVYPLDDRGTGRLISPKPTPSDPKRKHFTFYAGATRLAETASPNTKNKSHSITAEIELK
ECCEECCCCCCCCEECCCCCCCCCCCCEEEEEECHHHHHHCCCCCCCCCCCEEEEEEEEE
SKSDSGIIVASGGSSAGFALYVQNGKLVYHYNYFDDARYVITSKESLPVGKSTVRFDFAY
CCCCCCEEEECCCCCCCEEEEEECCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEEEE
DGGGTGKGGTGKLYINDKLVGEGRIDKTVAARFGIDTFGIGEDSGSPVANSYKLPFKFTG
CCCCCCCCCCEEEEECCEEECCCCCCHHHHHHHCCCEECCCCCCCCCCCCCEECCEEEEC
IIDKVEIDLK
EEEEEEEECC
>Mature Secondary Structure
MKSLISPKLLLILAVFLFSCNQSQKTDSVTEKTDSGELDRTILPIPEPPFGGKIGETYKD
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCEEECCCCCCCCCCCCCCHHC
SKEEWPKLVTPPQGAPNVIIILLDDVGFGQVSTFGGPVPTPELDKLAANGLKYNRFHTTA
CHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCEEECEEEEEE
ICGPSRAALLTGRNHHNAGSGFLAEWATGYPSYNCMIPKTTATSGRILKGNGYSTSWFGK
EECCCCEEEEECCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEECCCCCCCCCCC
NHNTPDWETSVTGPFDRWPTGLGFDYFYGFNAGETHQYYPVLFENTKAVEPDKSPEQGYH
CCCCCCCCCCCCCCHHHCCCCCCCHHEECCCCCCCCEEEEEEECCCCCCCCCCCHHHCCE
FMTDMTDRAINWLEYSKSVAPQKPVMLYFAPGAAHAPHHAPKEWRDKFKGQFDKGWDVVR
EHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCHHHHH
QETYERQLKMGIIPPKTKLTPRPDWVTPWDKLSADQKKLFARLMENYAGYLSFADHETGR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCEEEECCCCHHH
LLEAISKLPDADNTLIFYIVGDNGASSEGGMEGTVNEIKALSGISTPLADNLKHLDEIGG
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
PNTEPHYPVGWAWAGNAPFQWVKQVASHFGGSRNPMVVSWPKVIKDKGGMRSQFVHLIDV
CCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEECHHHHHCCCCHHHHHHHHHHH
LPTILDASHLPSPKSVDGVEQKPMDGVSFLSTFADKNAKPVRTRQYFEIFSNRAIYDNGW
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCE
VAATQHTFPWRQDFAPGNWDKDKWELYNIDEDYSESVDLAKKYPEKLKELKAIFDEEAKK
EEEECCCCCCHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YNVYPLDDRGTGRLISPKPTPSDPKRKHFTFYAGATRLAETASPNTKNKSHSITAEIELK
ECCEECCCCCCCCEECCCCCCCCCCCCEEEEEECHHHHHHCCCCCCCCCCCEEEEEEEEE
SKSDSGIIVASGGSSAGFALYVQNGKLVYHYNYFDDARYVITSKESLPVGKSTVRFDFAY
CCCCCCEEEECCCCCCCEEEEEECCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEEEEE
DGGGTGKGGTGKLYINDKLVGEGRIDKTVAARFGIDTFGIGEDSGSPVANSYKLPFKFTG
CCCCCCCCCCEEEEECCEEECCCCCCHHHHHHHCCCEECCCCCCCCCCCCCEECCEEEEC
IIDKVEIDLK
EEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]