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The map label for this gene is sglT [H]

Identifier: 146300861

GI number: 146300861

Start: 3690931

End: 3692499

Strand: Reverse

Name: sglT [H]

Synonym: Fjoh_3116

Alternate gene names: 146300861

Gene position: 3692499-3690931 (Counterclockwise)

Preceding gene: 146300862

Following gene: 146300860

Centisome position: 60.56

GC content: 37.22

Gene sequence:

>1569_bases
ATGTATATTTACAGAAGCAAAAAAACTGCAGCGACCAGTTCAAACGAATACTTTTTAGCCGAAGGCTCACTTACCTGGTG
GGCAATTGGAGCGTCGCTGATTGCTTCTAATATTTCAGCAGAACACTTTATTGGCATGAGTGGTTCGGGATTTGCCATCG
GACTTGCCATTGCTTCTTACGAATGGATGTCTGCCGCTACTTTGATTATCGTAGCAATGTTTATCCTGCCCATTTATCTT
AAGAATAAGATATTTACAATGCCGCAGTTTTTAGCCAAAAGATACAGCGGTACCGTAAGTACTATTATGGCAATTATATG
GCTGTTGATTTACGTATTTGTTAATCTTACCTCTATCATTTATCTGGGTGCTCTGGCAATTTCGTCTATTGCGCCCGTTA
GCTTTCAGTTTTGTGTTATCGGTTTGAGTTTATTCTCTGTTATTGTAACTTTAGGAGGAATGAAAGTCATAGGATATACT
GATATGTTTCAGGTTATTGTGTTAATTCTTGGAGGATTAGTAACCACTTATTTGGCATTGACTTTACTTTCAGATCAGTT
TGGTTTTGGAAAAGATATTCTAAAAGGTCTTGCTGTGATAGCAGATCAGGCGCCAGATCATCTACATATGATTTTAGACG
AATCCAATCCGCATTATAATGAATTGCCGGGAATGTCAGTTTTAGTGGGCGGAATGTTAATCAATAATCTGGCCTATTGG
GGATGTAATCAATATATTGTTCAAAGAGCTTTAGGAGCCGATTTGAAAACGGCAAGAAAAGGAATTTTATTTGCTGCTTT
TCTAAAATTATTAGTTCCAATTATTGCTGTTTTGCCAGGTATTGCCATGTTTGTAATGCACCAAAATGGAGCTTTCCAAC
AGGAAATGGTTGATGCTGCAGGAGTTTTAAAACCAGATCATGCATATCCAACTTTAATGAATTTGCTTCCTGCCGGATTA
AAAGGTGTGGCTTTAGCAGCTTTAACAGCGGCAATTGTAGCTTCTTTAGCAGGAAAGGCCAATAGCATTTCGACTATTTT
TTCTTTAGATATTTATAAAAAATATTTCAATTCGCAGGCATCAGAAAAAAAACTGGTTCGTACCGGAAGATGGTGTGTTG
TAGTTTGTATGATTATCGCGGCTTTTGTAGCGCCGGCATTAAAAACTTTAGATCAGGCATATCAGTTTATTCAGGAATAT
GTTGGTTTTTTCTCTCCAGGCGTTTTGGCGATTTTCTTATTGGGAATGTTTTGGAAAAAAACAACACCATCAGCTGGACT
CGCAGGCGCATTATTGACAGTGCCAATTGCCGCGGTTTTAAAATTCCTCCCGATGTGGACAGAAGGTACTTTCCCTGATT
ATCCATTTTTAGATAGAATGACTATTGTTTTCTTTATGATTGTATTCATAATGGTTGGTATTAGTTTAGCAAAACCAGCA
TCTGAGGAAGAGTCTGAAATTCATAAAATAGATGTAGATAAATCAATGTTCAAAGTCTCTTCTGAATTTATTGTAGGTTC
CTTTATTATCAGCGGGATATTAGTGGCTTTGTATACTGTTTTCTGGTAA

Upstream 100 bases:

>100_bases
TTACTATCTAACCACACAATAACCACACATTATGAATGTATTACAAACCGCAGATTACATTGTTTTCTTTATTTATTTTG
TCATAGTCACGGCTTATGGA

Downstream 100 bases:

>100_bases
ATTTTATTGCCACAGATTTTAAGATTAGAAAGGATTTTTTTCACGCAGATTCTGCAGATTTTGGCAGATTAAATTAAATT
TCTTTTAAAAAAATCCGTGG

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MYIYRSKKTAATSSNEYFLAEGSLTWWAIGASLIASNISAEHFIGMSGSGFAIGLAIASYEWMSAATLIIVAMFILPIYL
KNKIFTMPQFLAKRYSGTVSTIMAIIWLLIYVFVNLTSIIYLGALAISSIAPVSFQFCVIGLSLFSVIVTLGGMKVIGYT
DMFQVIVLILGGLVTTYLALTLLSDQFGFGKDILKGLAVIADQAPDHLHMILDESNPHYNELPGMSVLVGGMLINNLAYW
GCNQYIVQRALGADLKTARKGILFAAFLKLLVPIIAVLPGIAMFVMHQNGAFQQEMVDAAGVLKPDHAYPTLMNLLPAGL
KGVALAALTAAIVASLAGKANSISTIFSLDIYKKYFNSQASEKKLVRTGRWCVVVCMIIAAFVAPALKTLDQAYQFIQEY
VGFFSPGVLAIFLLGMFWKKTTPSAGLAGALLTVPIAAVLKFLPMWTEGTFPDYPFLDRMTIVFFMIVFIMVGISLAKPA
SEEESEIHKIDVDKSMFKVSSEFIVGSFIISGILVALYTVFW

Sequences:

>Translated_522_residues
MYIYRSKKTAATSSNEYFLAEGSLTWWAIGASLIASNISAEHFIGMSGSGFAIGLAIASYEWMSAATLIIVAMFILPIYL
KNKIFTMPQFLAKRYSGTVSTIMAIIWLLIYVFVNLTSIIYLGALAISSIAPVSFQFCVIGLSLFSVIVTLGGMKVIGYT
DMFQVIVLILGGLVTTYLALTLLSDQFGFGKDILKGLAVIADQAPDHLHMILDESNPHYNELPGMSVLVGGMLINNLAYW
GCNQYIVQRALGADLKTARKGILFAAFLKLLVPIIAVLPGIAMFVMHQNGAFQQEMVDAAGVLKPDHAYPTLMNLLPAGL
KGVALAALTAAIVASLAGKANSISTIFSLDIYKKYFNSQASEKKLVRTGRWCVVVCMIIAAFVAPALKTLDQAYQFIQEY
VGFFSPGVLAIFLLGMFWKKTTPSAGLAGALLTVPIAAVLKFLPMWTEGTFPDYPFLDRMTIVFFMIVFIMVGISLAKPA
SEEESEIHKIDVDKSMFKVSSEFIVGSFIISGILVALYTVFW
>Mature_522_residues
MYIYRSKKTAATSSNEYFLAEGSLTWWAIGASLIASNISAEHFIGMSGSGFAIGLAIASYEWMSAATLIIVAMFILPIYL
KNKIFTMPQFLAKRYSGTVSTIMAIIWLLIYVFVNLTSIIYLGALAISSIAPVSFQFCVIGLSLFSVIVTLGGMKVIGYT
DMFQVIVLILGGLVTTYLALTLLSDQFGFGKDILKGLAVIADQAPDHLHMILDESNPHYNELPGMSVLVGGMLINNLAYW
GCNQYIVQRALGADLKTARKGILFAAFLKLLVPIIAVLPGIAMFVMHQNGAFQQEMVDAAGVLKPDHAYPTLMNLLPAGL
KGVALAALTAAIVASLAGKANSISTIFSLDIYKKYFNSQASEKKLVRTGRWCVVVCMIIAAFVAPALKTLDQAYQFIQEY
VGFFSPGVLAIFLLGMFWKKTTPSAGLAGALLTVPIAAVLKFLPMWTEGTFPDYPFLDRMTIVFFMIVFIMVGISLAKPA
SEEESEIHKIDVDKSMFKVSSEFIVGSFIISGILVALYTVFW

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI17941285, Length=440, Percent_Identity=32.2727272727273, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI4507031, Length=427, Percent_Identity=31.1475409836066, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI110835708, Length=529, Percent_Identity=29.6786389413989, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI14140236, Length=448, Percent_Identity=29.0178571428571, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI4507033, Length=437, Percent_Identity=30.4347826086957, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI109659836, Length=468, Percent_Identity=32.2649572649573, Blast_Score=178, Evalue=9e-45,
Organism=Homo sapiens, GI109659839, Length=484, Percent_Identity=31.198347107438, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI206597483, Length=446, Percent_Identity=29.5964125560538, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI206597487, Length=471, Percent_Identity=28.6624203821656, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI256985183, Length=432, Percent_Identity=23.8425925925926, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4507035, Length=428, Percent_Identity=23.3644859813084, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI157671931, Length=361, Percent_Identity=22.4376731301939, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790113, Length=513, Percent_Identity=30.0194931773879, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI115533094, Length=424, Percent_Identity=20.7547169811321, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI161076631, Length=450, Percent_Identity=24.6666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920916, Length=459, Percent_Identity=24.6187363834423, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28573698, Length=452, Percent_Identity=24.1150442477876, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221379702, Length=408, Percent_Identity=23.7745098039216, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651741, Length=459, Percent_Identity=20.9150326797386, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364280, Length=436, Percent_Identity=22.9357798165138, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651739, Length=449, Percent_Identity=20.2672605790646, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 56843; Mature: 56843

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIYRSKKTAATSSNEYFLAEGSLTWWAIGASLIASNISAEHFIGMSGSGFAIGLAIASY
CCEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHEECCCCCCCEEHHHHHHH
EWMSAATLIIVAMFILPIYLKNKIFTMPQFLAKRYSGTVSTIMAIIWLLIYVFVNLTSII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YLGALAISSIAPVSFQFCVIGLSLFSVIVTLGGMKVIGYTDMFQVIVLILGGLVTTYLAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHH
TLLSDQFGFGKDILKGLAVIADQAPDHLHMILDESNPHYNELPGMSVLVGGMLINNLAYW
HHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
GCNQYIVQRALGADLKTARKGILFAAFLKLLVPIIAVLPGIAMFVMHQNGAFQQEMVDAA
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GVLKPDHAYPTLMNLLPAGLKGVALAALTAAIVASLAGKANSISTIFSLDIYKKYFNSQA
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
SEKKLVRTGRWCVVVCMIIAAFVAPALKTLDQAYQFIQEYVGFFSPGVLAIFLLGMFWKK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHC
TTPSAGLAGALLTVPIAAVLKFLPMWTEGTFPDYPFLDRMTIVFFMIVFIMVGISLAKPA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SEEESEIHKIDVDKSMFKVSSEFIVGSFIISGILVALYTVFW
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MYIYRSKKTAATSSNEYFLAEGSLTWWAIGASLIASNISAEHFIGMSGSGFAIGLAIASY
CCEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHEECCCCCCCEEHHHHHHH
EWMSAATLIIVAMFILPIYLKNKIFTMPQFLAKRYSGTVSTIMAIIWLLIYVFVNLTSII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YLGALAISSIAPVSFQFCVIGLSLFSVIVTLGGMKVIGYTDMFQVIVLILGGLVTTYLAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHH
TLLSDQFGFGKDILKGLAVIADQAPDHLHMILDESNPHYNELPGMSVLVGGMLINNLAYW
HHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
GCNQYIVQRALGADLKTARKGILFAAFLKLLVPIIAVLPGIAMFVMHQNGAFQQEMVDAA
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GVLKPDHAYPTLMNLLPAGLKGVALAALTAAIVASLAGKANSISTIFSLDIYKKYFNSQA
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
SEKKLVRTGRWCVVVCMIIAAFVAPALKTLDQAYQFIQEYVGFFSPGVLAIFLLGMFWKK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHC
TTPSAGLAGALLTVPIAAVLKFLPMWTEGTFPDYPFLDRMTIVFFMIVFIMVGISLAKPA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SEEESEIHKIDVDKSMFKVSSEFIVGSFIISGILVALYTVFW
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]