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The map label for this gene is bsaA [H]

Identifier: 146300693

GI number: 146300693

Start: 3490123

End: 3490710

Strand: Reverse

Name: bsaA [H]

Synonym: Fjoh_2944

Alternate gene names: 146300693

Gene position: 3490710-3490123 (Counterclockwise)

Preceding gene: 146300696

Following gene: 146300687

Centisome position: 57.25

GC content: 31.8

Gene sequence:

>588_bases
ATGAAAAAAATACTATTTATAGCTTGCAGTGCCATTTTTTTTATAAGTGCACAAGCTGAGGCTCAAACAAGCAAGAATAA
ATTATCTAAATCAGATAAGGCTATGGCAAAAGAAACAATTTACCAGTTTAAAGTAGAAGATTTATCAGGAGACACTTTTG
ATTTTGCGTCTTTAAAAGGCAAAAAAATCTTAATTGTAAATACAGCATCAAAATGCGGTTTAACGCCTCAATACAAAGAT
CTTGAAGCTGTTTATAAAGAATACAAAGATAAAGGATTTGTAATTGTTGGTTTTCCTGCAAACAACTTCGCATCGCAAGA
GCCTGGAACAAACAAAGAAATTGAAACTTTCTGCCAGCAGAATTACGGTGTAACTTTTCCTATGATGAACAAAGTTTCTG
TAAAAGGAGATGATATGTGCGATGTTTACAAATTCCTGACTCAAAAATCTAAAAACGGTTTACAGGATTCTGAAGTTGAA
TGGAATTTTCAAAAATACCTGATTAATGAAAAAGGTGAATTGGTTAAAGTAATCAAACCTAGAACTCTAGTAACAGAGCC
AGAAGTAATTAATTGGATAAAAAGCTAA

Upstream 100 bases:

>100_bases
CCAGGCTTCAATTTTTATTTAACTTATTATTAATAAAAATAAAGACTTCAAAATCATACGCCTGAAATACTTTTTAATTA
ATTTTATAAAAAATTATACA

Downstream 100 bases:

>100_bases
ATTAAAACTATCTAAACCGAAAAAATCCACAAATTTGAGTTTGTCAAATTTGTGGATTTTTTTTTAGTTGGTAAGGTACT
GAGGTTCTAAGGTACTAAGC

Product: glutathione peroxidase

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKKILFIACSAIFFISAQAEAQTSKNKLSKSDKAMAKETIYQFKVEDLSGDTFDFASLKGKKILIVNTASKCGLTPQYKD
LEAVYKEYKDKGFVIVGFPANNFASQEPGTNKEIETFCQQNYGVTFPMMNKVSVKGDDMCDVYKFLTQKSKNGLQDSEVE
WNFQKYLINEKGELVKVIKPRTLVTEPEVINWIKS

Sequences:

>Translated_195_residues
MKKILFIACSAIFFISAQAEAQTSKNKLSKSDKAMAKETIYQFKVEDLSGDTFDFASLKGKKILIVNTASKCGLTPQYKD
LEAVYKEYKDKGFVIVGFPANNFASQEPGTNKEIETFCQQNYGVTFPMMNKVSVKGDDMCDVYKFLTQKSKNGLQDSEVE
WNFQKYLINEKGELVKVIKPRTLVTEPEVINWIKS
>Mature_195_residues
MKKILFIACSAIFFISAQAEAQTSKNKLSKSDKAMAKETIYQFKVEDLSGDTFDFASLKGKKILIVNTASKCGLTPQYKD
LEAVYKEYKDKGFVIVGFPANNFASQEPGTNKEIETFCQQNYGVTFPMMNKVSVKGDDMCDVYKFLTQKSKNGLQDSEVE
WNFQKYLINEKGELVKVIKPRTLVTEPEVINWIKS

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI192455698, Length=143, Percent_Identity=40.5594405594406, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI15618997, Length=161, Percent_Identity=34.1614906832298, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI90903240, Length=173, Percent_Identity=31.7919075144509, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI75709200, Length=180, Percent_Identity=30.5555555555556, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI4557629, Length=201, Percent_Identity=30.8457711442786, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI90903238, Length=156, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI33186887, Length=186, Percent_Identity=30.6451612903226, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI6006001, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32967607, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI41406084, Length=179, Percent_Identity=26.2569832402235, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1788003, Length=177, Percent_Identity=35.0282485875706, Blast_Score=128, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17506887, Length=145, Percent_Identity=34.4827586206897, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17550320, Length=190, Percent_Identity=28.9473684210526, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI193210707, Length=153, Percent_Identity=33.9869281045752, Blast_Score=93, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17535473, Length=145, Percent_Identity=31.7241379310345, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71993584, Length=156, Percent_Identity=32.0512820512821, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193209493, Length=159, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71999642, Length=81, Percent_Identity=38.2716049382716, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71993573, Length=113, Percent_Identity=33.6283185840708, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322228, Length=148, Percent_Identity=50.6756756756757, Blast_Score=157, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6319721, Length=152, Percent_Identity=48.0263157894737, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322826, Length=152, Percent_Identity=43.421052631579, Blast_Score=129, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24656772, Length=188, Percent_Identity=33.5106382978723, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24656767, Length=150, Percent_Identity=37.3333333333333, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24656777, Length=150, Percent_Identity=37.3333333333333, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI85726443, Length=174, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: NA

Molecular weight: Translated: 22094; Mature: 22094

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILFIACSAIFFISAQAEAQTSKNKLSKSDKAMAKETIYQFKVEDLSGDTFDFASLKG
CCEEEEEHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEHHCCCC
KKILIVNTASKCGLTPQYKDLEAVYKEYKDKGFVIVGFPANNFASQEPGTNKEIETFCQQ
CEEEEEECCHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHH
NYGVTFPMMNKVSVKGDDMCDVYKFLTQKSKNGLQDSEVEWNFQKYLINEKGELVKVIKP
CCCEECCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCCEEEEECC
RTLVTEPEVINWIKS
CEECCCHHHHHHHCC
>Mature Secondary Structure
MKKILFIACSAIFFISAQAEAQTSKNKLSKSDKAMAKETIYQFKVEDLSGDTFDFASLKG
CCEEEEEHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEHHCCCC
KKILIVNTASKCGLTPQYKDLEAVYKEYKDKGFVIVGFPANNFASQEPGTNKEIETFCQQ
CEEEEEECCHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHH
NYGVTFPMMNKVSVKGDDMCDVYKFLTQKSKNGLQDSEVEWNFQKYLINEKGELVKVIKP
CCCEECCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCCEEEEECC
RTLVTEPEVINWIKS
CEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA