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The map label for this gene is menA [H]

Identifier: 146300535

GI number: 146300535

Start: 3318458

End: 3319420

Strand: Direct

Name: menA [H]

Synonym: Fjoh_2785

Alternate gene names: 146300535

Gene position: 3318458-3319420 (Clockwise)

Preceding gene: 146300534

Following gene: 146300536

Centisome position: 54.43

GC content: 34.06

Gene sequence:

>963_bases
ATGAAACACTGGATTGAAGCCGCAAGACTGCGCACATTGCCATTATCAGTTTCCGGAATTATAGTTGGAAGTATTTATGC
ACTTTCAAATCCAACAGAAACAATCAATACACCAACTGAAGTTTTCAGCTGGAAAATTTTTGGTTTCGCACTTTTAACAA
CACTTGGTTTACAGGTTTTATCCAATTTTGCCAACGACTACGGCGATGGTGTAAAAGGCACAGATAATGCTGACCGAGTA
GGGCCGCAGCGCGCTATTCAAAGTGGTATTATTACACCGCAGGCTATGAAAAAAGCCATAATACTAACTTCTGTATTGAC
TTTATTATCAGCAGTTATTTTGATTTATTTTGCCTTTGGAAAAGACAATTTCGGCTATTCGATATTTTTTCTTTTACTGG
GAATTGCTGCTATTATCTCAGCTATTCGTTACACTGTTGGAAACTCAGCTTACGGATATAAAGGATTTGGAGACTTATTT
GTTTTTATTTTCTTTGGTCTGGTTAGTACTTTAGGGGTTAATTTTTTATACGCCAAAGAAGTTGATCCTTTGTTAATTCT
TCCGGCAGTTTCAATAGGTTTATTAAGCGTAGGTGTTTTAAACCTAAACAATATGCGCGACGAAGAATCTGACCGAAAAT
CAGGTAAAAACACAATTGTAGTGCAAATGGGCGGTGCAAAAGCAAAAAAATACCATTATTTTTTAATTGTTACAGCAATG
CTTTTAATGGTAATTTTTGCCATTTTGAGCGATTATCGTTTCGATCAGTATTTGTTTTTAGTTGCTTATATTCCTTTAAC
TAAACATTTAATTACAGTTTATAAAAACCAAAATCCAAAGCTTTTAGATCCTGAATTAAAAAAACTGGCGCTAAGTACAT
TTTTGCTTTCTATACTATTAACTGTCTGCATGATTTCATTAATAGCAGATATTTTTGTTAATCTTTTCTTAGGCGGAAGA
TAA

Upstream 100 bases:

>100_bases
TTAAAAAACAATATTATCATTTAGATTACAGATTTTAGATTTTTAAAATTAAAAGAATCCAAAAATCTAAACTCTAAATT
CAAAAATCTAAAATTAAAAC

Downstream 100 bases:

>100_bases
AAATCAAGTTCAATTTAAAATTAAAAAAAATGAAAATAACATTCTACGGACACGCCTCTTTAGCGATTGAAGTTGGAGGA
AAACACATTATTGTCGATCC

Product: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Products: NA

Alternate protein names: DHNA-octaprenyltransferase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKHWIEAARLRTLPLSVSGIIVGSIYALSNPTETINTPTEVFSWKIFGFALLTTLGLQVLSNFANDYGDGVKGTDNADRV
GPQRAIQSGIITPQAMKKAIILTSVLTLLSAVILIYFAFGKDNFGYSIFFLLLGIAAIISAIRYTVGNSAYGYKGFGDLF
VFIFFGLVSTLGVNFLYAKEVDPLLILPAVSIGLLSVGVLNLNNMRDEESDRKSGKNTIVVQMGGAKAKKYHYFLIVTAM
LLMVIFAILSDYRFDQYLFLVAYIPLTKHLITVYKNQNPKLLDPELKKLALSTFLLSILLTVCMISLIADIFVNLFLGGR

Sequences:

>Translated_320_residues
MKHWIEAARLRTLPLSVSGIIVGSIYALSNPTETINTPTEVFSWKIFGFALLTTLGLQVLSNFANDYGDGVKGTDNADRV
GPQRAIQSGIITPQAMKKAIILTSVLTLLSAVILIYFAFGKDNFGYSIFFLLLGIAAIISAIRYTVGNSAYGYKGFGDLF
VFIFFGLVSTLGVNFLYAKEVDPLLILPAVSIGLLSVGVLNLNNMRDEESDRKSGKNTIVVQMGGAKAKKYHYFLIVTAM
LLMVIFAILSDYRFDQYLFLVAYIPLTKHLITVYKNQNPKLLDPELKKLALSTFLLSILLTVCMISLIADIFVNLFLGGR
>Mature_320_residues
MKHWIEAARLRTLPLSVSGIIVGSIYALSNPTETINTPTEVFSWKIFGFALLTTLGLQVLSNFANDYGDGVKGTDNADRV
GPQRAIQSGIITPQAMKKAIILTSVLTLLSAVILIYFAFGKDNFGYSIFFLLLGIAAIISAIRYTVGNSAYGYKGFGDLF
VFIFFGLVSTLGVNFLYAKEVDPLLILPAVSIGLLSVGVLNLNNMRDEESDRKSGKNTIVVQMGGAKAKKYHYFLIVTAM
LLMVIFAILSDYRFDQYLFLVAYIPLTKHLITVYKNQNPKLLDPELKKLALSTFLLSILLTVCMISLIADIFVNLFLGGR

Specific function: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK). Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA. The conversion of DHNA to DMK proceeds in three stages:the removal of the carboxyl group of DHNA

COG id: COG1575

COG function: function code H; 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the menA family [H]

Homologues:

Organism=Escherichia coli, GI1790365, Length=298, Percent_Identity=41.2751677852349, Blast_Score=223, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004657
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: =2.5.1.74 [H]

Molecular weight: Translated: 35239; Mature: 35239

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHWIEAARLRTLPLSVSGIIVGSIYALSNPTETINTPTEVFSWKIFGFALLTTLGLQVL
CCHHHHHHHHHCCCCEEHHHHEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SNFANDYGDGVKGTDNADRVGPQRAIQSGIITPQAMKKAIILTSVLTLLSAVILIYFAFG
HHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KDNFGYSIFFLLLGIAAIISAIRYTVGNSAYGYKGFGDLFVFIFFGLVSTLGVNFLYAKE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECC
VDPLLILPAVSIGLLSVGVLNLNNMRDEESDRKSGKNTIVVQMGGAKAKKYHYFLIVTAM
CCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
LLMVIFAILSDYRFDQYLFLVAYIPLTKHLITVYKNQNPKLLDPELKKLALSTFLLSILL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TVCMISLIADIFVNLFLGGR
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKHWIEAARLRTLPLSVSGIIVGSIYALSNPTETINTPTEVFSWKIFGFALLTTLGLQVL
CCHHHHHHHHHCCCCEEHHHHEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SNFANDYGDGVKGTDNADRVGPQRAIQSGIITPQAMKKAIILTSVLTLLSAVILIYFAFG
HHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KDNFGYSIFFLLLGIAAIISAIRYTVGNSAYGYKGFGDLFVFIFFGLVSTLGVNFLYAKE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECC
VDPLLILPAVSIGLLSVGVLNLNNMRDEESDRKSGKNTIVVQMGGAKAKKYHYFLIVTAM
CCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
LLMVIFAILSDYRFDQYLFLVAYIPLTKHLITVYKNQNPKLLDPELKKLALSTFLLSILL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TVCMISLIADIFVNLFLGGR
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]