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The map label for this gene is coaD

Identifier: 146300371

GI number: 146300371

Start: 3112431

End: 3112889

Strand: Reverse

Name: coaD

Synonym: Fjoh_2616

Alternate gene names: 146300371

Gene position: 3112889-3112431 (Counterclockwise)

Preceding gene: 146300372

Following gene: 146300370

Centisome position: 51.06

GC content: 35.51

Gene sequence:

>459_bases
ATGAGAAAAGCCATATTTCCAGGATCATTTGATCCTATTACACTTGGACACGAAGATATTATCAAAAGAGGAATCCCTTT
ATTTGATGAAATTGTAATTGCTATTGGTGTAAACGCCGAAAAAAAATACATGTTTTCATTAGAAGAAAGAAAACGCTTTA
TTGAAGAAACTTTTAAAGACGAGCCAAAAGTTTCGGTAATAACTTATGAAGGTTTAACCATTGATTTGGCTAAAAAGCAA
AAAGCTCATTTCATTTTAAGAGGTCTGCGCAACCCTGCCGATTTCGAATTTGAAAAAGCAATTGCACATACCAACAGAAA
ACTTTCTAAAATAGAAACAGTTTTCTTATTGACAGCCGCAAGTACCTCTTTTATCAGTTCGAGCATTGTGCGTGATGTAT
TGCGTCATGGAGGCGAATATGAAATGCTGGTTCCGGATGCGGTTCGGGTTAAGAAATAA

Upstream 100 bases:

>100_bases
AATAACCTAAAATAAAAATCCAAATTCCAAAAGCAAAGCTTAATCCCGATAACTATTGGTATAGCAACTTAAAATATCAG
AACCTTAGAACCTCAAAAAA

Downstream 100 bases:

>100_bases
AAACTCTAAACGGCATTGCGAGACACCAAGCAATCGCATATACAACAATCAAAAGCATAAATTTGCCAGCGAAGCAAATT
ATAAGTAATTTCGCATTTTT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRKAIFPGSFDPITLGHEDIIKRGIPLFDEIVIAIGVNAEKKYMFSLEERKRFIEETFKDEPKVSVITYEGLTIDLAKKQ
KAHFILRGLRNPADFEFEKAIAHTNRKLSKIETVFLLTAASTSFISSSIVRDVLRHGGEYEMLVPDAVRVKK

Sequences:

>Translated_152_residues
MRKAIFPGSFDPITLGHEDIIKRGIPLFDEIVIAIGVNAEKKYMFSLEERKRFIEETFKDEPKVSVITYEGLTIDLAKKQ
KAHFILRGLRNPADFEFEKAIAHTNRKLSKIETVFLLTAASTSFISSSIVRDVLRHGGEYEMLVPDAVRVKK
>Mature_152_residues
MRKAIFPGSFDPITLGHEDIIKRGIPLFDEIVIAIGVNAEKKYMFSLEERKRFIEETFKDEPKVSVITYEGLTIDLAKKQ
KAHFILRGLRNPADFEFEKAIAHTNRKLSKIETVFLLTAASTSFISSSIVRDVLRHGGEYEMLVPDAVRVKK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=149, Percent_Identity=42.2818791946309, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_FLAJ1 (A5FGN1)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001194962.1
- ProteinModelPortal:   A5FGN1
- SMR:   A5FGN1
- STRING:   A5FGN1
- GeneID:   5093511
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_2616
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   FJOH376686:FJOH_2616-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17325; Mature: 17325

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAIFPGSFDPITLGHEDIIKRGIPLFDEIVIAIGVNAEKKYMFSLEERKRFIEETFKD
CCCCCCCCCCCCEECCHHHHHHCCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHCC
EPKVSVITYEGLTIDLAKKQKAHFILRGLRNPADFEFEKAIAHTNRKLSKIETVFLLTAA
CCCEEEEEECCEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECC
STSFISSSIVRDVLRHGGEYEMLVPDAVRVKK
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MRKAIFPGSFDPITLGHEDIIKRGIPLFDEIVIAIGVNAEKKYMFSLEERKRFIEETFKD
CCCCCCCCCCCCEECCHHHHHHCCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHCC
EPKVSVITYEGLTIDLAKKQKAHFILRGLRNPADFEFEKAIAHTNRKLSKIETVFLLTAA
CCCEEEEEECCEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECC
STSFISSSIVRDVLRHGGEYEMLVPDAVRVKK
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA