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The map label for this gene is prc [H]

Identifier: 146300316

GI number: 146300316

Start: 3046081

End: 3048111

Strand: Reverse

Name: prc [H]

Synonym: Fjoh_2561

Alternate gene names: 146300316

Gene position: 3048111-3046081 (Counterclockwise)

Preceding gene: 146300317

Following gene: 146300315

Centisome position: 49.99

GC content: 32.79

Gene sequence:

>2031_bases
ATGAGAAAATTTTCGCCGCTGTTTTTACTGATTACCTCTTTCCTATTTAGTCAAAATAGCGCGGAGACATGCGAAATACT
GAACAAAATAAATGCAGTTATCCAAACTGAACATCTAAGACCAAAACCTGTAGATGACAGCTTGTCTGTTTTTGTTTTTG
ATAATTTAATCAACGAATTAGATCCGTCCCGAAACATTTTCTTTAAAAGTGAATATGACGAATTAGCTGCTAAATATCGT
TTAAATATTGACGATTTAATACTTGAAAATGACTGCAGTTTTTTGACTGATATTACGGCAAAGTATATAAATGGATTAAT
AAGAACAAAGGAAGTTCTCGAAAAGATTCAGTCGACCGCTTTTGATTATACGAAGAAAGATACTATTCGATTTTATAAAA
AATCATTCGCTTTTTACCTTAAAAAAGAAGATCTGGAAAAAGTATGGCGTAAAAAACTCCGCTATCAAATCCTGGATGAT
ATAGCCGAAGTAAGTAACAATTTAGATTCCATAAAAACCAACTTTAATTCGATTGAAGCAAAATCCAGAAAACTGATTTT
GTCAAATGAAATATGCCGTATAAGCACGCTTTTGGAAACTAAAACAAAACAAGACGAAAATCTGTATAATTTCTTTTGCA
CTTATTTTGATCCGCATACAGCTTATTTTAGCAATGATTCTAAATCGAGTTTTGTAGCGTCATTATCAAAAGAACATTTA
TCTTTAGGAATGACCGTTAATTTAAACGAAAAAAATGAAATTATTGTACACGAAATTGACCCAAATGGTCCAGCTTACCA
AACAGGATTGATAAAAAAAGGAGATCAGATTATTTCGGTTTCTAACCATAAAGAAACGCTTCAGGTATCGTGTGCTTCAT
TAGAATCTATTTCTACAATGATTATGTCTGAAGCTAATAAAAGCCTTACGCTTACGCTGAAAAGAAACTCAGGCAAAAAC
TTTGACGTGCATATTGAAAAGCAAGTTATGAAAGACGAAGAAAATTCGGTTTTCAGTTTTATAATAGGTAAAGAAAGTAA
AATAGGTTACATAAAAATTCCGAGTTTTTATGCTGATTTAGATGGAAACAGCCGTAAAGGCTGCGCCGATGATGTAGCAC
GCGAAGTTATTAAACTCGAAAGAGATAATATTAAAGGTCTCGTTATTGATTTAATTGATAATGGCGGTGGTTCTATGGAA
GAGGCTATAAAACTGGCCGGAATGTTTATTGATTACGGGCCTCTTTCGATAGTAGTCGATCATACTAAAGAAAAATCAGT
AATAAACGATCCATACAAAGGTCTAATTTACAGAGGTCCAATTGTGGTTTTGGTAAATAGCAACACGGCTTCGGCAAGTG
AATTCTTTTCTTCTATCATGCAGGATTACAATAGAGCGCTTTTACTTGGAAGCAGTACGCTTGGAAAAGCTACCATGCAG
ACGATTCTTTCGCTGGACGAAACTAAAAATACAGATTTCTTAAAAATTACAATCAATAAGTTTTATCGCGTTACTGGAAA
AAGTCATCAATATATTGGCGTTACTCCAGATGTTGTTCTTCCGGAATTTTATGAAGATGTTTATCAAAAAGAAAGTGATT
TTCCTACTGCTATTAAAAATGACAGTATTGAATCTGTTCTAAAATACCGCCCTTATGTAAAACGCAGCCTGATTGATAAA
ATAGCTAAAAACAGTACTTTGAGGCTAGCTGACAATTATTATTTTAACGGAATTAAAAAAATCAATCAAAAAATAGATCA
GCTGGTTAATACTCCAAAAGCAGAAATTCCGATGACTTTAGATGCTGTTTTTAAACAGAAAAAAGTTGTGAATTCACTTT
GGACTGAGATTAACACTTTTAATGACGAGAACAATCCGCTGGATGTTTACAACTCTTCTGTAAATCAGCTTTTATTAGGC
GTTTATCCAAACGACAAAACAATCAACCAATATCAAATGGATAATTTGAAAACAAATCCTTATCTAAACGAAGCCGTAAA
TATTATTAATGAGTTTAACGGTTCGAAGTAA

Upstream 100 bases:

>100_bases
AAGTTTAGATCGAGTATTTATCTGTAAGATTTTTTAGAAATAATATAAAATCGTATCACAAAATTAGCGTAACTTTAATG
TAGATATTGACATCAAACTT

Downstream 100 bases:

>100_bases
GCTCTTTTTTTCAAGTTTGAGGTTTCAAGTTAAAAACTGAGACTGCAAACCTGAAACAAATAGAAAAAACTTAAATTTTG
ATTTTGGATAAATAAGGAAT

Product: C-terminal processing peptidase

Products: NA

Alternate protein names: C-terminal-processing peptidase; Protease Re [H]

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MRKFSPLFLLITSFLFSQNSAETCEILNKINAVIQTEHLRPKPVDDSLSVFVFDNLINELDPSRNIFFKSEYDELAAKYR
LNIDDLILENDCSFLTDITAKYINGLIRTKEVLEKIQSTAFDYTKKDTIRFYKKSFAFYLKKEDLEKVWRKKLRYQILDD
IAEVSNNLDSIKTNFNSIEAKSRKLILSNEICRISTLLETKTKQDENLYNFFCTYFDPHTAYFSNDSKSSFVASLSKEHL
SLGMTVNLNEKNEIIVHEIDPNGPAYQTGLIKKGDQIISVSNHKETLQVSCASLESISTMIMSEANKSLTLTLKRNSGKN
FDVHIEKQVMKDEENSVFSFIIGKESKIGYIKIPSFYADLDGNSRKGCADDVAREVIKLERDNIKGLVIDLIDNGGGSME
EAIKLAGMFIDYGPLSIVVDHTKEKSVINDPYKGLIYRGPIVVLVNSNTASASEFFSSIMQDYNRALLLGSSTLGKATMQ
TILSLDETKNTDFLKITINKFYRVTGKSHQYIGVTPDVVLPEFYEDVYQKESDFPTAIKNDSIESVLKYRPYVKRSLIDK
IAKNSTLRLADNYYFNGIKKINQKIDQLVNTPKAEIPMTLDAVFKQKKVVNSLWTEINTFNDENNPLDVYNSSVNQLLLG
VYPNDKTINQYQMDNLKTNPYLNEAVNIINEFNGSK

Sequences:

>Translated_676_residues
MRKFSPLFLLITSFLFSQNSAETCEILNKINAVIQTEHLRPKPVDDSLSVFVFDNLINELDPSRNIFFKSEYDELAAKYR
LNIDDLILENDCSFLTDITAKYINGLIRTKEVLEKIQSTAFDYTKKDTIRFYKKSFAFYLKKEDLEKVWRKKLRYQILDD
IAEVSNNLDSIKTNFNSIEAKSRKLILSNEICRISTLLETKTKQDENLYNFFCTYFDPHTAYFSNDSKSSFVASLSKEHL
SLGMTVNLNEKNEIIVHEIDPNGPAYQTGLIKKGDQIISVSNHKETLQVSCASLESISTMIMSEANKSLTLTLKRNSGKN
FDVHIEKQVMKDEENSVFSFIIGKESKIGYIKIPSFYADLDGNSRKGCADDVAREVIKLERDNIKGLVIDLIDNGGGSME
EAIKLAGMFIDYGPLSIVVDHTKEKSVINDPYKGLIYRGPIVVLVNSNTASASEFFSSIMQDYNRALLLGSSTLGKATMQ
TILSLDETKNTDFLKITINKFYRVTGKSHQYIGVTPDVVLPEFYEDVYQKESDFPTAIKNDSIESVLKYRPYVKRSLIDK
IAKNSTLRLADNYYFNGIKKINQKIDQLVNTPKAEIPMTLDAVFKQKKVVNSLWTEINTFNDENNPLDVYNSSVNQLLLG
VYPNDKTINQYQMDNLKTNPYLNEAVNIINEFNGSK
>Mature_676_residues
MRKFSPLFLLITSFLFSQNSAETCEILNKINAVIQTEHLRPKPVDDSLSVFVFDNLINELDPSRNIFFKSEYDELAAKYR
LNIDDLILENDCSFLTDITAKYINGLIRTKEVLEKIQSTAFDYTKKDTIRFYKKSFAFYLKKEDLEKVWRKKLRYQILDD
IAEVSNNLDSIKTNFNSIEAKSRKLILSNEICRISTLLETKTKQDENLYNFFCTYFDPHTAYFSNDSKSSFVASLSKEHL
SLGMTVNLNEKNEIIVHEIDPNGPAYQTGLIKKGDQIISVSNHKETLQVSCASLESISTMIMSEANKSLTLTLKRNSGKN
FDVHIEKQVMKDEENSVFSFIIGKESKIGYIKIPSFYADLDGNSRKGCADDVAREVIKLERDNIKGLVIDLIDNGGGSME
EAIKLAGMFIDYGPLSIVVDHTKEKSVINDPYKGLIYRGPIVVLVNSNTASASEFFSSIMQDYNRALLLGSSTLGKATMQ
TILSLDETKNTDFLKITINKFYRVTGKSHQYIGVTPDVVLPEFYEDVYQKESDFPTAIKNDSIESVLKYRPYVKRSLIDK
IAKNSTLRLADNYYFNGIKKINQKIDQLVNTPKAEIPMTLDAVFKQKKVVNSLWTEINTFNDENNPLDVYNSSVNQLLLG
VYPNDKTINQYQMDNLKTNPYLNEAVNIINEFNGSK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=585, Percent_Identity=27.6923076923077, Blast_Score=193, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 77034; Mature: 77034

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFSPLFLLITSFLFSQNSAETCEILNKINAVIQTEHLRPKPVDDSLSVFVFDNLINEL
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHC
DPSRNIFFKSEYDELAAKYRLNIDDLILENDCSFLTDITAKYINGLIRTKEVLEKIQSTA
CCCCCEEEECCHHHHHHHHCCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDYTKKDTIRFYKKSFAFYLKKEDLEKVWRKKLRYQILDDIAEVSNNLDSIKTNFNSIEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHH
KSRKLILSNEICRISTLLETKTKQDENLYNFFCTYFDPHTAYFSNDSKSSFVASLSKEHL
HCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCCHHHHHHHHHHHH
SLGMTVNLNEKNEIIVHEIDPNGPAYQTGLIKKGDQIISVSNHKETLQVSCASLESISTM
EEEEEEEECCCCCEEEEEECCCCCCEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
IMSEANKSLTLTLKRNSGKNFDVHIEKQVMKDEENSVFSFIIGKESKIGYIKIPSFYADL
HHHCCCCEEEEEEECCCCCCEEEEEHHHHHCCCCCCEEEEEEECCCCEEEEECCCEEECC
DGNSRKGCADDVAREVIKLERDNIKGLVIDLIDNGGGSMEEAIKLAGMFIDYGPLSIVVD
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHEEECCCEEEEEE
HTKEKSVINDPYKGLIYRGPIVVLVNSNTASASEFFSSIMQDYNRALLLGSSTLGKATMQ
CCCCCCCCCCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHH
TILSLDETKNTDFLKITINKFYRVTGKSHQYIGVTPDVVLPEFYEDVYQKESDFPTAIKN
HHHHHHCCCCCCEEEEEEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCC
DSIESVLKYRPYVKRSLIDKIAKNSTLRLADNYYFNGIKKINQKIDQLVNTPKAEIPMTL
CCHHHHHHHCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHH
DAVFKQKKVVNSLWTEINTFNDENNPLDVYNSSVNQLLLGVYPNDKTINQYQMDNLKTNP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCHHCCCCCCCCC
YLNEAVNIINEFNGSK
CHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRKFSPLFLLITSFLFSQNSAETCEILNKINAVIQTEHLRPKPVDDSLSVFVFDNLINEL
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHC
DPSRNIFFKSEYDELAAKYRLNIDDLILENDCSFLTDITAKYINGLIRTKEVLEKIQSTA
CCCCCEEEECCHHHHHHHHCCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDYTKKDTIRFYKKSFAFYLKKEDLEKVWRKKLRYQILDDIAEVSNNLDSIKTNFNSIEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHH
KSRKLILSNEICRISTLLETKTKQDENLYNFFCTYFDPHTAYFSNDSKSSFVASLSKEHL
HCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEECCCCCHHHHHHHHHHHH
SLGMTVNLNEKNEIIVHEIDPNGPAYQTGLIKKGDQIISVSNHKETLQVSCASLESISTM
EEEEEEEECCCCCEEEEEECCCCCCEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
IMSEANKSLTLTLKRNSGKNFDVHIEKQVMKDEENSVFSFIIGKESKIGYIKIPSFYADL
HHHCCCCEEEEEEECCCCCCEEEEEHHHHHCCCCCCEEEEEEECCCCEEEEECCCEEECC
DGNSRKGCADDVAREVIKLERDNIKGLVIDLIDNGGGSMEEAIKLAGMFIDYGPLSIVVD
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHEEECCCEEEEEE
HTKEKSVINDPYKGLIYRGPIVVLVNSNTASASEFFSSIMQDYNRALLLGSSTLGKATMQ
CCCCCCCCCCCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHH
TILSLDETKNTDFLKITINKFYRVTGKSHQYIGVTPDVVLPEFYEDVYQKESDFPTAIKN
HHHHHHCCCCCCEEEEEEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCC
DSIESVLKYRPYVKRSLIDKIAKNSTLRLADNYYFNGIKKINQKIDQLVNTPKAEIPMTL
CCHHHHHHHCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHH
DAVFKQKKVVNSLWTEINTFNDENNPLDVYNSSVNQLLLGVYPNDKTINQYQMDNLKTNP
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCHHCCCCCCCCC
YLNEAVNIINEFNGSK
CHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]