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The map label for this gene is ascR [H]

Identifier: 145301463

GI number: 145301463

Start: 77288

End: 77941

Strand: Direct

Name: ascR [H]

Synonym: ASA_P5G080

Alternate gene names: 145301463

Gene position: 77288-77941 (Clockwise)

Preceding gene: 145301462

Following gene: 145301464

Centisome position: 49.83

GC content: 58.87

Gene sequence:

>654_bases
ATGATCCAGTTGCCAGACGAGCTAAACCTTATCGTCGGGCTGGCGCTGCTGGCCCTGCTCCCCTTTATCGCCGTGATGGC
CACCTCCTTCGTCAAGCTGGCGGTGGTCTTCTCGCTGCTGCGCAATGCCCTCGGGGTGCAGCAGATCCCCCCCAACATGG
CAATGTACGGGCTGGCGATCATCCTCAGCATCTATGTGATGGCGCCGGTCGGCTTTGCCACCCAAGATTACTTGCGCCAG
AACGAGGTGTCGCTGGCCAAATCCGAATCGGTGGAGAAGTTTCTCGACGAGGGGATTGCCCCCTACCGCGACTTTTTGAA
AAAGCAGATCAAACCGCGGGAGCACGCCTTCTTTATCGACAGTACCAAGCAGCTCTGGCCCAGCAAATATGCCGACCGGC
TGGAGCCCGACAGCCTGCTGATCCTGCTGCCAGCCTTTACCGTGAGCGAGCTGAGCCGAGCCTTCGAGATCGGCTTTCTG
ATCTACCTGCCCTTTATCGCCATCGACCTCATCATCTCCAACATTCTGCTGGCGATGGGGATGATGATGGTCTCCCCCAT
GACCATCTCGCTGCCCTTCAAGTTGCTGCTGTTTGTGCTGCTCGATGGCTGGGCCCGCCTGACCCACGGGCTGGTCATCA
GTTACGGAGGCTAG

Upstream 100 bases:

>100_bases
GCATCATCAGCAACGGCCATTTGCTGGGAGTGGGCCGACTGGTGGAGATCCAGGGGCGCCTGGGTGTACGGGTCGAGCGC
CTCGACAACGAGTCACTGTC

Downstream 100 bases:

>100_bases
CATGAGTCACGCCGATATCCTTCACTTCACCAGCCAGGCGCTCTGGCTGGTGTTGATCCTCTCCATGCCACCGGTACTGG
TGGCGGCACTGGTGGGCACC

Product: type III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MIQLPDELNLIVGLALLALLPFIAVMATSFVKLAVVFSLLRNALGVQQIPPNMAMYGLAIILSIYVMAPVGFATQDYLRQ
NEVSLAKSESVEKFLDEGIAPYRDFLKKQIKPREHAFFIDSTKQLWPSKYADRLEPDSLLILLPAFTVSELSRAFEIGFL
IYLPFIAIDLIISNILLAMGMMMVSPMTISLPFKLLLFVLLDGWARLTHGLVISYGG

Sequences:

>Translated_217_residues
MIQLPDELNLIVGLALLALLPFIAVMATSFVKLAVVFSLLRNALGVQQIPPNMAMYGLAIILSIYVMAPVGFATQDYLRQ
NEVSLAKSESVEKFLDEGIAPYRDFLKKQIKPREHAFFIDSTKQLWPSKYADRLEPDSLLILLPAFTVSELSRAFEIGFL
IYLPFIAIDLIISNILLAMGMMMVSPMTISLPFKLLLFVLLDGWARLTHGLVISYGG
>Mature_217_residues
MIQLPDELNLIVGLALLALLPFIAVMATSFVKLAVVFSLLRNALGVQQIPPNMAMYGLAIILSIYVMAPVGFATQDYLRQ
NEVSLAKSESVEKFLDEGIAPYRDFLKKQIKPREHAFFIDSTKQLWPSKYADRLEPDSLLILLPAFTVSELSRAFEIGFL
IYLPFIAIDLIISNILLAMGMMMVSPMTISLPFKLLLFVLLDGWARLTHGLVISYGG

Specific function: Component of the yop secretion machinery. May have a role in the negative pathway regulation of yop expression controlled by calcium [H]

COG id: COG4790

COG function: function code U; Type III secretory pathway, component EscR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family [H]

Homologues:

Organism=Escherichia coli, GI1788259, Length=199, Percent_Identity=41.2060301507538, Blast_Score=148, Evalue=3e-37,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005838
- InterPro:   IPR005773 [H]

Pfam domain/function: PF00813 FliP [H]

EC number: NA

Molecular weight: Translated: 24196; Mature: 24196

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS01060 FLIP_1 ; PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQLPDELNLIVGLALLALLPFIAVMATSFVKLAVVFSLLRNALGVQQIPPNMAMYGLAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ILSIYVMAPVGFATQDYLRQNEVSLAKSESVEKFLDEGIAPYRDFLKKQIKPREHAFFID
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHEEEEC
STKQLWPSKYADRLEPDSLLILLPAFTVSELSRAFEIGFLIYLPFIAIDLIISNILLAMG
CHHHHCHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMMVSPMTISLPFKLLLFVLLDGWARLTHGLVISYGG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure
MIQLPDELNLIVGLALLALLPFIAVMATSFVKLAVVFSLLRNALGVQQIPPNMAMYGLAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ILSIYVMAPVGFATQDYLRQNEVSLAKSESVEKFLDEGIAPYRDFLKKQIKPREHAFFID
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHEEEEC
STKQLWPSKYADRLEPDSLLILLPAFTVSELSRAFEIGFLIYLPFIAIDLIISNILLAMG
CHHHHCHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMMVSPMTISLPFKLLLFVLLDGWARLTHGLVISYGG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8300512; 9746557; 9748454; 11586360 [H]