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The map label for this gene is cvrA [H]

Identifier: 145299811

GI number: 145299811

Start: 3117199

End: 3118407

Strand: Direct

Name: cvrA [H]

Synonym: ASA_2892

Alternate gene names: 145299811

Gene position: 3117199-3118407 (Clockwise)

Preceding gene: 145299810

Following gene: 145299813

Centisome position: 66.29

GC content: 61.95

Gene sequence:

>1209_bases
ATGGACGCATCCCTGATCTACCAGAACCTGGCGGTGCTTGCCGCCTTCTTGCTGATCTACAGCCTGCTCGCAGGTCGCTT
CGAATCCAGATTGATCAATGGCCCCTTGCTGTTCCTGCTGATGGGCTGGCTGCTGGGGCCAGGCGGGCTCGGTCTGATGT
CACTCTCGGTCGACAGCGAGGGGATAAAGCTGCTGGCAGAGCTCACCCTGGTCATAGTGCTGTTCAATGACGCCGCCAAC
ACCAACTGGCAAGTATTGGCAGCCAACCGCGCCCTCCCCATACGATTGCTGCTCATCGGCCTGCCACTCACCCTGCTGGG
GGGCACCCTGTTCGGCCTCTGGCTCTACCCGGATCTGCCGCTGCTGGAGCTGGCCATCCTCTCCACCATTCTCGCCCCCA
CAGATGCGGCGCTCGGCAAGGCCGTGGTCAGCAATCCGGCCGTGCCCGCGCCCATCAGGGAGGGGCTCAATCAGGAGAGC
GGCCTCAACGACGGTATCTGCGTGCCAGTGCTCTTGCTGCTGCTCGCCCTCATCGCCCCCACCGAACAACACGCCGGCAC
GGGCATGCTGGCCATAACCTTGCTGCTGGAAGAGATAGGCATAGGCCTGCTGGTGGCCCTGGTGCTCACCAGCCTCACCA
TACGGCTGCTGAAAACCTCCTACCTCAACGGCTGGCAACTGCCGCTCTGGCGCCAGCTCACCATGCCAGGGCTGGCCCTG
CTCTGCTTTGCGCTTGCCCAGACCCTGGGGGGCAGCGGTTTTATCGCCGCCTTCGTCGGGGGTCTCTTGATGGGCCGCAG
ACTGGGGGATCACAAACACGCTTACATGGATAGCTGCGAAGGGTATGGGGACCTGCTCTCCGTGGTGATCTGGATGGTGT
TCGGCGCCACCCTGATGCCCATGCTGCCGGATCTGCTGCACTGGCAATACTGGCTCTATGCCGTCGCCAGCCTGACCCTG
CTGCGCATGCTGCCGGTCTGGCTGAGCCTGCTGGGGACAGGACTAAAACCCGAGTTGATACTCTTCATCGGATGGTTCGG
ACCAAGGGGGCTCGCCAGCATTGTCTTTGCCGTCATGGTGTTGCAACACGAGCCAGCGCTGCTGGGACAAGAACCCATCA
TAGCCACTGTGCTTTGCACCATCATACTGAGCGTCATCTTGCACGGTATCAGTGCCAACCCCTGGGTCAGGCGCTTCAAG
ACGGCGTAA

Upstream 100 bases:

>100_bases
GTGTAAACGAAATCTTGCGCTGGCTGGCCGGTGAATATGTGTTTGATCCTGACTGCCTGACCGACTGAGACAAGCCACGC
CAGATGCCACAGGAGGCTGC

Downstream 100 bases:

>100_bases
ATACCCGACAGTGGCCAAAGGTATGGCAGAGGGGATAAACAACCTCATCACCATTGCGGTATAAAACAATACCCCCAGTC
AGGACTGGGGGTATTGTGGA

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MDASLIYQNLAVLAAFLLIYSLLAGRFESRLINGPLLFLLMGWLLGPGGLGLMSLSVDSEGIKLLAELTLVIVLFNDAAN
TNWQVLAANRALPIRLLLIGLPLTLLGGTLFGLWLYPDLPLLELAILSTILAPTDAALGKAVVSNPAVPAPIREGLNQES
GLNDGICVPVLLLLLALIAPTEQHAGTGMLAITLLLEEIGIGLLVALVLTSLTIRLLKTSYLNGWQLPLWRQLTMPGLAL
LCFALAQTLGGSGFIAAFVGGLLMGRRLGDHKHAYMDSCEGYGDLLSVVIWMVFGATLMPMLPDLLHWQYWLYAVASLTL
LRMLPVWLSLLGTGLKPELILFIGWFGPRGLASIVFAVMVLQHEPALLGQEPIIATVLCTIILSVILHGISANPWVRRFK
TA

Sequences:

>Translated_402_residues
MDASLIYQNLAVLAAFLLIYSLLAGRFESRLINGPLLFLLMGWLLGPGGLGLMSLSVDSEGIKLLAELTLVIVLFNDAAN
TNWQVLAANRALPIRLLLIGLPLTLLGGTLFGLWLYPDLPLLELAILSTILAPTDAALGKAVVSNPAVPAPIREGLNQES
GLNDGICVPVLLLLLALIAPTEQHAGTGMLAITLLLEEIGIGLLVALVLTSLTIRLLKTSYLNGWQLPLWRQLTMPGLAL
LCFALAQTLGGSGFIAAFVGGLLMGRRLGDHKHAYMDSCEGYGDLLSVVIWMVFGATLMPMLPDLLHWQYWLYAVASLTL
LRMLPVWLSLLGTGLKPELILFIGWFGPRGLASIVFAVMVLQHEPALLGQEPIIATVLCTIILSVILHGISANPWVRRFK
TA
>Mature_402_residues
MDASLIYQNLAVLAAFLLIYSLLAGRFESRLINGPLLFLLMGWLLGPGGLGLMSLSVDSEGIKLLAELTLVIVLFNDAAN
TNWQVLAANRALPIRLLLIGLPLTLLGGTLFGLWLYPDLPLLELAILSTILAPTDAALGKAVVSNPAVPAPIREGLNQES
GLNDGICVPVLLLLLALIAPTEQHAGTGMLAITLLLEEIGIGLLVALVLTSLTIRLLKTSYLNGWQLPLWRQLTMPGLAL
LCFALAQTLGGSGFIAAFVGGLLMGRRLGDHKHAYMDSCEGYGDLLSVVIWMVFGATLMPMLPDLLHWQYWLYAVASLTL
LRMLPVWLSLLGTGLKPELILFIGWFGPRGLASIVFAVMVLQHEPALLGQEPIIATVLCTIILSVILHGISANPWVRRFK
TA

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 43298; Mature: 43298

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASLIYQNLAVLAAFLLIYSLLAGRFESRLINGPLLFLLMGWLLGPGGLGLMSLSVDSE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCHH
GIKLLAELTLVIVLFNDAANTNWQVLAANRALPIRLLLIGLPLTLLGGTLFGLWLYPDLP
HHHHHHHHHHHHHEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LLELAILSTILAPTDAALGKAVVSNPAVPAPIREGLNQESGLNDGICVPVLLLLLALIAP
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
TEQHAGTGMLAITLLLEEIGIGLLVALVLTSLTIRLLKTSYLNGWQLPLWRQLTMPGLAL
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHH
LCFALAQTLGGSGFIAAFVGGLLMGRRLGDHKHAYMDSCEGYGDLLSVVIWMVFGATLMP
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MLPDLLHWQYWLYAVASLTLLRMLPVWLSLLGTGLKPELILFIGWFGPRGLASIVFAVMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHH
LQHEPALLGQEPIIATVLCTIILSVILHGISANPWVRRFKTA
HHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure
MDASLIYQNLAVLAAFLLIYSLLAGRFESRLINGPLLFLLMGWLLGPGGLGLMSLSVDSE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCHH
GIKLLAELTLVIVLFNDAANTNWQVLAANRALPIRLLLIGLPLTLLGGTLFGLWLYPDLP
HHHHHHHHHHHHHEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
LLELAILSTILAPTDAALGKAVVSNPAVPAPIREGLNQESGLNDGICVPVLLLLLALIAP
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
TEQHAGTGMLAITLLLEEIGIGLLVALVLTSLTIRLLKTSYLNGWQLPLWRQLTMPGLAL
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHH
LCFALAQTLGGSGFIAAFVGGLLMGRRLGDHKHAYMDSCEGYGDLLSVVIWMVFGATLMP
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MLPDLLHWQYWLYAVASLTLLRMLPVWLSLLGTGLKPELILFIGWFGPRGLASIVFAVMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHH
LQHEPALLGQEPIIATVLCTIILSVILHGISANPWVRRFKTA
HHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]