Click here to switch to the map view.

The map label for this gene is nagJ [H]

Identifier: 145299810

GI number: 145299810

Start: 3116063

End: 3117166

Strand: Direct

Name: nagJ [H]

Synonym: ASA_2891

Alternate gene names: 145299810

Gene position: 3116063-3117166 (Clockwise)

Preceding gene: 145299809

Following gene: 145299811

Centisome position: 66.27

GC content: 62.23

Gene sequence:

>1104_bases
ATGCCTTACCAAACCGAGTTGTCTGGCCTGCAACCCCCTTTTCCCAATCTGGGATTGATAGAGGGATTCTTTGGCAAGGG
CTGGAGCTGGGAAGCCCGCGCCCGCTACGCTCAATGGCTGCCACGCCACGGCTACGGCTTCTACATCTATGCCCCGAAAG
AAGATGGCTATCTGCGCAAGCACTGGGCCCTGCCCTGGCCAGAAGCCGAGCTCGAGGCTCTGCGCCAGCTGGCCCGCCAG
TGCCGCGACAACGGCCTCGCCTTCGGGGTGGGCTTGAGCCCCATGGGTGCCCACCACGACTATGATCGCAAGCGCCCGGC
CCTGTTGGAGAAGGTGCGCCTCATCGACGAAGCGCTGCAGCCTGACATACTGGCTGTGCTGTTCGACGACATGAAGGGGG
ATACCCCGGATCTGGCCCACCACCAGCTCACCATAGCCCACGACATTGCGGCCCACAGCAAGGCCGGCCGTCTCATCTTC
TGCCCCAGCTACTACTCCACGGATCCCGTGCTGGAAAAGGTGTTCGGCGCCATGCCCCCCCGCTATCTGGAGGATATAGG
CCAGCAACTCGACCGCCGTTTCGAGATCTTCTGGACAGGCCCCAGGGTCTGCTCCAGCGAATACCCGGCCCCCCACCTCA
AACAGGTGACCGAGCTGCTCGGGCGCAAACCCTTTTTGTGGGACAACTACCCGGTCAACGATGGTAGCAAGGCCAGCAGC
TTCCTGCACCTGCGCGCCTTCGAGAATCGTCCGGCAGAACTTGTGGAGCTGGTCGCGGGCCACGCAGTCAACCCCATGAA
GCAGGCGGCGCTCTCTGTGCTGCCGCTCGCCACCCTGCCCATGAGCTACCGGCTCGGCAAGCAGTATGATGCTGACAAGG
CGCTGCACGCCTCCCTCAATGCCACCTGCGGGCCGCAGATTTCGGCGATGATAGAGGCAGACCTGCCGCTGTTTCAGGAC
ATGGGGCTGGCCCTGCTCACCCAGGAGCAGATCGCCCATCTCAAGCGCCGTTACCTGCCGTTTCAGGATCAGGTGTGTGT
AAACGAAATCTTGCGCTGGCTGGCCGGTGAATATGTGTTTGATCCTGACTGCCTGACCGACTGA

Upstream 100 bases:

>100_bases
TGGAAGAGGGCAAGCCCCGCAAGATAGGGGTGCGCTTTCAGGAAGAAGACCCGGTCTGACGCACATCGTCTGACCCGCCT
TTGCGAGCAGGGAGTTCATT

Downstream 100 bases:

>100_bases
GACAAGCCACGCCAGATGCCACAGGAGGCTGCATGGACGCATCCCTGATCTACCAGAACCTGGCGGTGCTTGCCGCCTTC
TTGCTGATCTACAGCCTGCT

Product: hyaluronidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; Beta-hexosaminidase; GH84; Hexosaminidase B; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MPYQTELSGLQPPFPNLGLIEGFFGKGWSWEARARYAQWLPRHGYGFYIYAPKEDGYLRKHWALPWPEAELEALRQLARQ
CRDNGLAFGVGLSPMGAHHDYDRKRPALLEKVRLIDEALQPDILAVLFDDMKGDTPDLAHHQLTIAHDIAAHSKAGRLIF
CPSYYSTDPVLEKVFGAMPPRYLEDIGQQLDRRFEIFWTGPRVCSSEYPAPHLKQVTELLGRKPFLWDNYPVNDGSKASS
FLHLRAFENRPAELVELVAGHAVNPMKQAALSVLPLATLPMSYRLGKQYDADKALHASLNATCGPQISAMIEADLPLFQD
MGLALLTQEQIAHLKRRYLPFQDQVCVNEILRWLAGEYVFDPDCLTD

Sequences:

>Translated_367_residues
MPYQTELSGLQPPFPNLGLIEGFFGKGWSWEARARYAQWLPRHGYGFYIYAPKEDGYLRKHWALPWPEAELEALRQLARQ
CRDNGLAFGVGLSPMGAHHDYDRKRPALLEKVRLIDEALQPDILAVLFDDMKGDTPDLAHHQLTIAHDIAAHSKAGRLIF
CPSYYSTDPVLEKVFGAMPPRYLEDIGQQLDRRFEIFWTGPRVCSSEYPAPHLKQVTELLGRKPFLWDNYPVNDGSKASS
FLHLRAFENRPAELVELVAGHAVNPMKQAALSVLPLATLPMSYRLGKQYDADKALHASLNATCGPQISAMIEADLPLFQD
MGLALLTQEQIAHLKRRYLPFQDQVCVNEILRWLAGEYVFDPDCLTD
>Mature_366_residues
PYQTELSGLQPPFPNLGLIEGFFGKGWSWEARARYAQWLPRHGYGFYIYAPKEDGYLRKHWALPWPEAELEALRQLARQC
RDNGLAFGVGLSPMGAHHDYDRKRPALLEKVRLIDEALQPDILAVLFDDMKGDTPDLAHHQLTIAHDIAAHSKAGRLIFC
PSYYSTDPVLEKVFGAMPPRYLEDIGQQLDRRFEIFWTGPRVCSSEYPAPHLKQVTELLGRKPFLWDNYPVNDGSKASSF
LHLRAFENRPAELVELVAGHAVNPMKQAALSVLPLATLPMSYRLGKQYDADKALHASLNATCGPQISAMIEADLPLFQDM
GLALLTQEQIAHLKRRYLPFQDQVCVNEILRWLAGEYVFDPDCLTD

Specific function: Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fibronectin type-III domain [H]

Homologues:

Organism=Homo sapiens, GI11024698, Length=331, Percent_Identity=27.190332326284, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI215490056, Length=278, Percent_Identity=28.0575539568345, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI193211004, Length=274, Percent_Identity=30.6569343065693, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193211002, Length=274, Percent_Identity=30.6569343065693, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24648670, Length=295, Percent_Identity=26.7796610169492, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR011496
- InterPro:   IPR008965
- InterPro:   IPR000421
- InterPro:   IPR018452
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR008979
- InterPro:   IPR017853
- InterPro:   IPR013783 [H]

Pfam domain/function: PF00754 F5_F8_type_C; PF00041 fn3; PF02838 Glyco_hydro_20b; PF07555 NAGidase [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 41612; Mature: 41481

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYQTELSGLQPPFPNLGLIEGFFGKGWSWEARARYAQWLPRHGYGFYIYAPKEDGYLRK
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
HWALPWPEAELEALRQLARQCRDNGLAFGVGLSPMGAHHDYDRKRPALLEKVRLIDEALQ
HCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PDILAVLFDDMKGDTPDLAHHQLTIAHDIAAHSKAGRLIFCPSYYSTDPVLEKVFGAMPP
CHHHHHHHHHHCCCCCCHHHHEEHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHCCCH
RYLEDIGQQLDRRFEIFWTGPRVCSSEYPAPHLKQVTELLGRKPFLWDNYPVNDGSKASS
HHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
FLHLRAFENRPAELVELVAGHAVNPMKQAALSVLPLATLPMSYRLGKQYDADKALHASLN
EEEEEHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHCC
ATCGPQISAMIEADLPLFQDMGLALLTQEQIAHLKRRYLPFQDQVCVNEILRWLAGEYVF
CCCCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEE
DPDCLTD
CCCCCCC
>Mature Secondary Structure 
PYQTELSGLQPPFPNLGLIEGFFGKGWSWEARARYAQWLPRHGYGFYIYAPKEDGYLRK
CCCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
HWALPWPEAELEALRQLARQCRDNGLAFGVGLSPMGAHHDYDRKRPALLEKVRLIDEALQ
HCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PDILAVLFDDMKGDTPDLAHHQLTIAHDIAAHSKAGRLIFCPSYYSTDPVLEKVFGAMPP
CHHHHHHHHHHCCCCCCHHHHEEHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHCCCH
RYLEDIGQQLDRRFEIFWTGPRVCSSEYPAPHLKQVTELLGRKPFLWDNYPVNDGSKASS
HHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
FLHLRAFENRPAELVELVAGHAVNPMKQAALSVLPLATLPMSYRLGKQYDADKALHASLN
EEEEEHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHCC
ATCGPQISAMIEADLPLFQDMGLALLTQEQIAHLKRRYLPFQDQVCVNEILRWLAGEYVF
CCCCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEE
DPDCLTD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA