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The map label for this gene is gntK [H]

Identifier: 145296486

GI number: 145296486

Start: 2635877

End: 2636380

Strand: Direct

Name: gntK [H]

Synonym: cgR_2397

Alternate gene names: 145296486

Gene position: 2635877-2636380 (Clockwise)

Preceding gene: 145296485

Following gene: 145296487

Centisome position: 79.53

GC content: 58.13

Gene sequence:

>504_bases
ATGTCAGCAGCCGAAGGCTTACACATTGTCATTATGGGCGTTTCCGGCTGCGGCAAATCCTCCGTCGGGGAAGCCCTAGC
AGCGGAGCTCGGAATCGAATACAAAGACGGCGACGAACTTCACCCCCAGGAAAACATCGACAAGATGGCCTCCGGCCGGG
CACTTGACGACGACGACCGTGCATGGTGGCTAGTCCAAGTTGGCAAGTGGCTCCGCGGCCGGCCAAGCGGCGTCATCGCA
TGCTCCGCCCTCAAGCGCTCCTACCGCGATCTCCTGCGCACCAAATGCCCAGGAACCGTCTTCGTCCACCTCCACGGCGA
CTACGATCTCCTACTTTCCCGCATGAAGGCCCGCGAAGATCACTTCATGCCATCCACCTTGCTAGATTCCCAATTTGCAA
CCCTCGAGCCGCTCGAAGATGACGAAGATGGCAAGGTTTTCGACGTTGCCCATACCATCAGCGAACTGGCCGCCCAATCT
GCAGAATGGGTTCGCAACAAATAA

Upstream 100 bases:

>100_bases
CTTACAAAATTCTCCAAAAGGAGTTATGATAGTACCAATACGTTTTTGTGGCAGCCTCCTGCATTCGGCAGTCGAGACGC
CACCAAAGAAAGGGTAAGAC

Downstream 100 bases:

>100_bases
ACCCCTAACCCATATTAGAACAAGGATTTGTGCGCTTTTCCTGTTCTGGTGTGGGTTTTCCTCACATCTAACAATCGAAT
AACTGTTCGAATAAAAGGTT

Product: hypothetical protein

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSAAEGLHIVIMGVSGCGKSSVGEALAAELGIEYKDGDELHPQENIDKMASGRALDDDDRAWWLVQVGKWLRGRPSGVIA
CSALKRSYRDLLRTKCPGTVFVHLHGDYDLLLSRMKAREDHFMPSTLLDSQFATLEPLEDDEDGKVFDVAHTISELAAQS
AEWVRNK

Sequences:

>Translated_167_residues
MSAAEGLHIVIMGVSGCGKSSVGEALAAELGIEYKDGDELHPQENIDKMASGRALDDDDRAWWLVQVGKWLRGRPSGVIA
CSALKRSYRDLLRTKCPGTVFVHLHGDYDLLLSRMKAREDHFMPSTLLDSQFATLEPLEDDEDGKVFDVAHTISELAAQS
AEWVRNK
>Mature_166_residues
SAAEGLHIVIMGVSGCGKSSVGEALAAELGIEYKDGDELHPQENIDKMASGRALDDDDRAWWLVQVGKWLRGRPSGVIAC
SALKRSYRDLLRTKCPGTVFVHLHGDYDLLLSRMKAREDHFMPSTLLDSQFATLEPLEDDEDGKVFDVAHTISELAAQSA
EWVRNK

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=181, Percent_Identity=40.8839779005525, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI87082265, Length=164, Percent_Identity=44.5121951219512, Blast_Score=135, Evalue=1e-33,
Organism=Escherichia coli, GI1790719, Length=164, Percent_Identity=42.6829268292683, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25146487, Length=143, Percent_Identity=48.951048951049, Blast_Score=133, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6320454, Length=141, Percent_Identity=39.0070921985816, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18455; Mature: 18324

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAEGLHIVIMGVSGCGKSSVGEALAAELGIEYKDGDELHPQENIDKMASGRALDDDDR
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
AWWLVQVGKWLRGRPSGVIACSALKRSYRDLLRTKCPGTVFVHLHGDYDLLLSRMKARED
EEEHEEHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
HFMPSTLLDSQFATLEPLEDDEDGKVFDVAHTISELAAQSAEWVRNK
CCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAAEGLHIVIMGVSGCGKSSVGEALAAELGIEYKDGDELHPQENIDKMASGRALDDDDR
CCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
AWWLVQVGKWLRGRPSGVIACSALKRSYRDLLRTKCPGTVFVHLHGDYDLLLSRMKARED
EEEHEEHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHH
HFMPSTLLDSQFATLEPLEDDEDGKVFDVAHTISELAAQSAEWVRNK
CCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]