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The map label for this gene is uxaC [H]

Identifier: 145296485

GI number: 145296485

Start: 2633618

End: 2635723

Strand: Direct

Name: uxaC [H]

Synonym: cgR_2396

Alternate gene names: 145296485

Gene position: 2633618-2635723 (Clockwise)

Preceding gene: 145296484

Following gene: 145296486

Centisome position: 79.47

GC content: 53.61

Gene sequence:

>2106_bases
GTGACTACCAAAGTCAAGGAGCGAACGGCAGGTGGCACCCTGCCCAATCATCGCGTGCTGACCTATGCATTTGGCGACAT
CGCCAACAACCTCATGTTCAGCATGACCTCGATGTTCATCATGGTGTATATGACCGACATCGTGGGTATTTCGGCAGCTG
TTGCCGGCACCATTTACGGTCTGACCAAGATTTGGGCCGGTGCTGCCGACCTCATCGCTGGGCAAACCGTCGACCGTTTC
CAAACCAAGTGGGGTCGCCTGCGCCCCTGGATGCTCTTTGGCTCCACCCCCTTGGCCATCGTTTTCGTCTTACTGTTTAG
CACCCCGGCCGGACTCACCGGCGCTGCAGCGATTGCCTGGATTTTCCTGCTCGATGCCCTCTTCCAATTGGCATATTCCT
TTGTCAACATCCCGTATGGCTCATTATCAGCTTCGATGACACAGGACCCCGTGGATCGTTCCAGGCTTTCTGGTGCGCGC
TCGATCACTTCTTCACTTGCCAGCGTTTTGCTCTCTGCTGTTGTTGCTCCGCAATTTGCAGATACCGCAGCGGACAACAT
GCGCTTGAAGTTCACGATCACCTGTTTGATTCTTGGTGTCATCGCGGTTTGCCTTTACCTCATTTGTTTTGCCAACTCCC
GCGAGGTGGTGCCCCGCCCCGAAGGCAAAATTTCTTTCAAGTCAACATTCACCATGATCGGCCACAACCGCCCGCTGATT
ATTCTGTGTGCGGCAACTTTCTTCCTGCTTTGCGGCATGTTCACCAATAACGCAGTGGCAATGTATTTCACTCGCGATGT
ATTGGGCAATGCTTCCTGGTTCACTTGGCTCATGCTGGCTCAAACAGCAGGATCTATCCTCGTTGCAACGCTGATTCCTT
CCATCACTGTACGCATTGGCAAACGCAATGGTTTCATGATGGCCGCCTGCTTTGTCATTGCTGGCTACCTGCTGATATTT
ATCATCCCAACAGGTCAGCTCATGCCCGCTGTATTCACGTGGTTCCTCCTGGGCATCGGCATTGGTTGCACCAATGCGCT
GATCTTCTCCATGGAAGCAGACACCGTGGATTATGGTGAATGGAACTCCAATATCCGCGCCGAGGGCGGCACCTATTCGG
TGGTCTCCTTTATCCGCAAGTGTGGTCAAGGTATCGGTGGTTGGATTGGTGGTGCTGTAATCGCAGCATTTGGCTATGTT
TCTATGGCTGGCGGATCCCAGAGCGCTGAGGCAGTGCAGGGTATCCGCATCGCAACCGGTGCAATACCCGCAGCTTTTGC
GGTCATTGCTTTGCTGCTGATCATCGCCTACCGACTAGATGCAGCAAGGCATGCTGAAATCATCGACGACCTCAACGAGC
GCCGCATGCAAAACGCTGTTGCAGACCGCCAAGGCGTGTCCTCTGACCAGGTACAGATCGTAGAAATCGGCGATGGTCGC
AACACCATCATGCGCCCCATCGGCGAGGATCACCCACCAATCATCACAGTGTTCGGCCAGCGTGGTTCTGGTGCCTCAGA
TATCGCCCCGATGATCGCTGAACGACTAGGCGTCACATACATCCCCCAGGCGTTTAGCTCCGACACCTTGGCTCAGGTTG
ATAAGAAGGACCTTATCTCTGACAGCAGTTTCAACCGCTGGCTGCGTACGGTTTCCCTTGGATCGACCCAGGATGCCGAT
ATGGCTGCAGCTTCCAACTTGGCAGCCAATTCTAAAATGGCCCGCCAGAACACCCGCGATGTCCTCGACGCAGTCTCTGA
TGGTGGCGTCATGCTCGGCCGAAACGGTGCCCTAGTGTTGGGACCTGTGGTTGGAACTCTCCACATTAAATTCATTGCGC
CTTTGAACAAGCGTGTGGAAAGAGTCATGTACAAAACTGGACTCTCAGAAGCTGCTGCAGCTGAACAATGCGCCTTGGAG
GATCGTCTCCGCGAAGAGATGGCCCACGCTTTGTATCAATGGAATCCCGGTCGTGATGAAGACTATGACCTCGTGATCAA
CACCGGTTCGATGACATACGAACAAATCGTTGATCTAGTTGTGGAAACTTACGCCAGGAAGTATCCGCTCCACGTGAGAA
TCATTCCGAACGGAAAAGACCAATAA

Upstream 100 bases:

>100_bases
TTCTTAGAACCCATCAGTTTTAACAGTGCCACCTGCCGGCCAGCCTTTATTTGTTTAGTCTCCGGAACTTGGCACTAATT
TAGATACCTGGAGATTTTTC

Downstream 100 bases:

>100_bases
ACATACAGTCCCCGTGATGTGACCATACACACCACGGGGACTGTGGCGTAGGTCTTACAAAATTCTCCAAAAGGAGTTAT
GATAGTACCAATACGTTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 701; Mature: 700

Protein sequence:

>701_residues
MTTKVKERTAGGTLPNHRVLTYAFGDIANNLMFSMTSMFIMVYMTDIVGISAAVAGTIYGLTKIWAGAADLIAGQTVDRF
QTKWGRLRPWMLFGSTPLAIVFVLLFSTPAGLTGAAAIAWIFLLDALFQLAYSFVNIPYGSLSASMTQDPVDRSRLSGAR
SITSSLASVLLSAVVAPQFADTAADNMRLKFTITCLILGVIAVCLYLICFANSREVVPRPEGKISFKSTFTMIGHNRPLI
ILCAATFFLLCGMFTNNAVAMYFTRDVLGNASWFTWLMLAQTAGSILVATLIPSITVRIGKRNGFMMAACFVIAGYLLIF
IIPTGQLMPAVFTWFLLGIGIGCTNALIFSMEADTVDYGEWNSNIRAEGGTYSVVSFIRKCGQGIGGWIGGAVIAAFGYV
SMAGGSQSAEAVQGIRIATGAIPAAFAVIALLLIIAYRLDAARHAEIIDDLNERRMQNAVADRQGVSSDQVQIVEIGDGR
NTIMRPIGEDHPPIITVFGQRGSGASDIAPMIAERLGVTYIPQAFSSDTLAQVDKKDLISDSSFNRWLRTVSLGSTQDAD
MAAASNLAANSKMARQNTRDVLDAVSDGGVMLGRNGALVLGPVVGTLHIKFIAPLNKRVERVMYKTGLSEAAAAEQCALE
DRLREEMAHALYQWNPGRDEDYDLVINTGSMTYEQIVDLVVETYARKYPLHVRIIPNGKDQ

Sequences:

>Translated_701_residues
MTTKVKERTAGGTLPNHRVLTYAFGDIANNLMFSMTSMFIMVYMTDIVGISAAVAGTIYGLTKIWAGAADLIAGQTVDRF
QTKWGRLRPWMLFGSTPLAIVFVLLFSTPAGLTGAAAIAWIFLLDALFQLAYSFVNIPYGSLSASMTQDPVDRSRLSGAR
SITSSLASVLLSAVVAPQFADTAADNMRLKFTITCLILGVIAVCLYLICFANSREVVPRPEGKISFKSTFTMIGHNRPLI
ILCAATFFLLCGMFTNNAVAMYFTRDVLGNASWFTWLMLAQTAGSILVATLIPSITVRIGKRNGFMMAACFVIAGYLLIF
IIPTGQLMPAVFTWFLLGIGIGCTNALIFSMEADTVDYGEWNSNIRAEGGTYSVVSFIRKCGQGIGGWIGGAVIAAFGYV
SMAGGSQSAEAVQGIRIATGAIPAAFAVIALLLIIAYRLDAARHAEIIDDLNERRMQNAVADRQGVSSDQVQIVEIGDGR
NTIMRPIGEDHPPIITVFGQRGSGASDIAPMIAERLGVTYIPQAFSSDTLAQVDKKDLISDSSFNRWLRTVSLGSTQDAD
MAAASNLAANSKMARQNTRDVLDAVSDGGVMLGRNGALVLGPVVGTLHIKFIAPLNKRVERVMYKTGLSEAAAAEQCALE
DRLREEMAHALYQWNPGRDEDYDLVINTGSMTYEQIVDLVVETYARKYPLHVRIIPNGKDQ
>Mature_700_residues
TTKVKERTAGGTLPNHRVLTYAFGDIANNLMFSMTSMFIMVYMTDIVGISAAVAGTIYGLTKIWAGAADLIAGQTVDRFQ
TKWGRLRPWMLFGSTPLAIVFVLLFSTPAGLTGAAAIAWIFLLDALFQLAYSFVNIPYGSLSASMTQDPVDRSRLSGARS
ITSSLASVLLSAVVAPQFADTAADNMRLKFTITCLILGVIAVCLYLICFANSREVVPRPEGKISFKSTFTMIGHNRPLII
LCAATFFLLCGMFTNNAVAMYFTRDVLGNASWFTWLMLAQTAGSILVATLIPSITVRIGKRNGFMMAACFVIAGYLLIFI
IPTGQLMPAVFTWFLLGIGIGCTNALIFSMEADTVDYGEWNSNIRAEGGTYSVVSFIRKCGQGIGGWIGGAVIAAFGYVS
MAGGSQSAEAVQGIRIATGAIPAAFAVIALLLIIAYRLDAARHAEIIDDLNERRMQNAVADRQGVSSDQVQIVEIGDGRN
TIMRPIGEDHPPIITVFGQRGSGASDIAPMIAERLGVTYIPQAFSSDTLAQVDKKDLISDSSFNRWLRTVSLGSTQDADM
AAASNLAANSKMARQNTRDVLDAVSDGGVMLGRNGALVLGPVVGTLHIKFIAPLNKRVERVMYKTGLSEAAAAEQCALED
RLREEMAHALYQWNPGRDEDYDLVINTGSMTYEQIVDLVVETYARKYPLHVRIIPNGKDQ

Specific function: Unknown

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI122937339, Length=483, Percent_Identity=23.8095238095238, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI1787902, Length=447, Percent_Identity=36.0178970917226, Blast_Score=288, Evalue=9e-79,
Organism=Escherichia coli, GI48994989, Length=463, Percent_Identity=26.5658747300216, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI145693206, Length=464, Percent_Identity=25, Blast_Score=170, Evalue=4e-43,
Organism=Escherichia coli, GI87082306, Length=459, Percent_Identity=27.0152505446623, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786466, Length=442, Percent_Identity=26.9230769230769, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1790561, Length=454, Percent_Identity=25.5506607929515, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 75760; Mature: 75629

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKVKERTAGGTLPNHRVLTYAFGDIANNLMFSMTSMFIMVYMTDIVGISAAVAGTIYG
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTKIWAGAADLIAGQTVDRFQTKWGRLRPWMLFGSTPLAIVFVLLFSTPAGLTGAAAIAW
HHHHHCCHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHH
IFLLDALFQLAYSFVNIPYGSLSASMTQDPVDRSRLSGARSITSSLASVLLSAVVAPQFA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DTAADNMRLKFTITCLILGVIAVCLYLICFANSREVVPRPEGKISFKSTFTMIGHNRPLI
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCEE
ILCAATFFLLCGMFTNNAVAMYFTRDVLGNASWFTWLMLAQTAGSILVATLIPSITVRIG
EEHHHHHHHHHHHHCCCEEEEEEEHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHEEEEE
KRNGFMMAACFVIAGYLLIFIIPTGQLMPAVFTWFLLGIGIGCTNALIFSMEADTVDYGE
CCCCHHHHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
WNSNIRAEGGTYSVVSFIRKCGQGIGGWIGGAVIAAFGYVSMAGGSQSAEAVQGIRIATG
CCCCEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHEECC
AIPAAFAVIALLLIIAYRLDAARHAEIIDDLNERRMQNAVADRQGVSSDQVQIVEIGDGR
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
NTIMRPIGEDHPPIITVFGQRGSGASDIAPMIAERLGVTYIPQAFSSDTLAQVDKKDLIS
CHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHCC
DSSFNRWLRTVSLGSTQDADMAAASNLAANSKMARQNTRDVLDAVSDGGVMLGRNGALVL
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEE
GPVVGTLHIKFIAPLNKRVERVMYKTGLSEAAAAEQCALEDRLREEMAHALYQWNPGRDE
ECCEEEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DYDLVINTGSMTYEQIVDLVVETYARKYPLHVRIIPNGKDQ
CCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCC
>Mature Secondary Structure 
TTKVKERTAGGTLPNHRVLTYAFGDIANNLMFSMTSMFIMVYMTDIVGISAAVAGTIYG
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTKIWAGAADLIAGQTVDRFQTKWGRLRPWMLFGSTPLAIVFVLLFSTPAGLTGAAAIAW
HHHHHCCHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHHHH
IFLLDALFQLAYSFVNIPYGSLSASMTQDPVDRSRLSGARSITSSLASVLLSAVVAPQFA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DTAADNMRLKFTITCLILGVIAVCLYLICFANSREVVPRPEGKISFKSTFTMIGHNRPLI
HCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCEE
ILCAATFFLLCGMFTNNAVAMYFTRDVLGNASWFTWLMLAQTAGSILVATLIPSITVRIG
EEHHHHHHHHHHHHCCCEEEEEEEHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHEEEEE
KRNGFMMAACFVIAGYLLIFIIPTGQLMPAVFTWFLLGIGIGCTNALIFSMEADTVDYGE
CCCCHHHHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCC
WNSNIRAEGGTYSVVSFIRKCGQGIGGWIGGAVIAAFGYVSMAGGSQSAEAVQGIRIATG
CCCCEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHEECC
AIPAAFAVIALLLIIAYRLDAARHAEIIDDLNERRMQNAVADRQGVSSDQVQIVEIGDGR
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
NTIMRPIGEDHPPIITVFGQRGSGASDIAPMIAERLGVTYIPQAFSSDTLAQVDKKDLIS
CHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHCC
DSSFNRWLRTVSLGSTQDADMAAASNLAANSKMARQNTRDVLDAVSDGGVMLGRNGALVL
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEE
GPVVGTLHIKFIAPLNKRVERVMYKTGLSEAAAAEQCALEDRLREEMAHALYQWNPGRDE
ECCEEEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DYDLVINTGSMTYEQIVDLVVETYARKYPLHVRIIPNGKDQ
CCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]