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The map label for this gene is hemY [H]

Identifier: 145294555

GI number: 145294555

Start: 566401

End: 567747

Strand: Direct

Name: hemY [H]

Synonym: cgR_0506

Alternate gene names: 145294555

Gene position: 566401-567747 (Clockwise)

Preceding gene: 145294554

Following gene: 145294556

Centisome position: 17.09

GC content: 59.47

Gene sequence:

>1347_bases
ATGCGTTTTGCCATCATCGGTGCAGGCCTTGCGGGTCTGACTGCTGCATATGAGATCCATAAAGCTGATCCCACTGCCCA
AATCGATGTGTTGGAAGCAGGCGAACGCATTGGCGGCAAGCTTTTTACGGTGCCGTTTGCTTCCGGACCTACCGATATTG
GAGCGGAGGCGTTTTTAGCTGCGCGTTCCGATGCGGTGGAGTTTTTTACTGAGCTTGGGTTGGCTGATTCTTTGGTCAGC
CCGTCTGCTGCGAAGTCTCAGTATTTCGCGGGCGGTGCGCTGCATGCGTTCCCCGCAGGTGGAGTGATGGGTATTCCAAG
CAATCCACCAGCAGGCGCGCAAGACACCGCTTTTGATTGGACTCCTGGCCACGATATTTCTGTTGGCGCCTTAGTGCGCC
GTCAGTATGGCGATGAGATCGTCGATACTGTGGTGTCTTCGCTGCTTGGTGGCGTTTATTCGTCCACAGCTGATGATCTG
GGTGTGCGCGCTTCCGTGCCGGCACTTGCTGCAGCCCTTGATCAGCTGGCTGAGGCCGGCGAGCCGGTGACTCTGTCAGC
TGCGGTCAAGGCCGTGGAAGCTCAGCGGGAAGCCGCAAAAACAACTTCAGAAACCCGCCCCGTTTTCCAGACCTTTAAGG
GCGGATACGCGGAGCTGTACGAAGCGTTGGCAGAGCAATGCGGTGCAGATATTCACTTGGATAGTTTCGTTTCCGCCATC
ACCAAAGATGGTGAAGGTTTTGCCATCAAGGGCGGTGGCGAAGGCACCTACGACAAGGTGATTTTGGCGGTTCCCGCTCC
GACCGCCGCTGTGCTGCTCCGCGACTTGGCACCGACCGCAGCGCCACATTTGCGCGCAATTAAGTTGGCTTCTTCAGCAG
TCGTCGGCATGCGTTTCGATTCCAGCGAGGGCCTGCCCGACAACTCCGGCGTCCTGGTCGCTGTTAATGAGCCGGGCATC
ACGGCGAAGGCCTTCACGTTCTCCTCAAAGAAGTGGCCTCACCTGGAGGCTCGCGGGGGCGCGCTCGTGCGCGCGTCGTT
CGGCAGGCTGGGCGATGAGGCGTCGGCACGCATGGACGAGGATTTGCTTGTCGACGCCGCCCTCGACGATCTCCTCACCA
TAACCGGGTTCGACGGCCGGGCTGCCGGACTGGGTGAAATTTTCGTGCAGCGCTGGTTCGGTGGGCTCCCAGCCTATGGA
GTTGATCACATTGCTGCCGTTTCGGCTGCGCGTGCAGAGATCGCAGCCGTGCCTGGCGTGGAAGCAATTGGCGCGTGGGC
TGGGGGAGTGGGAGTTCCCGCAGTTATCGCAGATGCCCAGGCAGCAGTACACAGGTTGCTGGGATAA

Upstream 100 bases:

>100_bases
CCATATCTTTAACCTTGGTCATGGTGTGCTTCCTAATACGGTGGCGGAAGATATTACTGAAGCCGTCTCCATCATTCATT
CTTAAACTAAGAGGAGTTTC

Downstream 100 bases:

>100_bases
GCACCCAAAAACACTATTGAACACCCCAATCGCTGTTGAGAGTTTGTAAAGTTCGACTGTCAACGAGCTGGATTGGCTTC
ACAGATTGAATTAATACAAT

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRFAIIGAGLAGLTAAYEIHKADPTAQIDVLEAGERIGGKLFTVPFASGPTDIGAEAFLAARSDAVEFFTELGLADSLVS
PSAAKSQYFAGGALHAFPAGGVMGIPSNPPAGAQDTAFDWTPGHDISVGALVRRQYGDEIVDTVVSSLLGGVYSSTADDL
GVRASVPALAAALDQLAEAGEPVTLSAAVKAVEAQREAAKTTSETRPVFQTFKGGYAELYEALAEQCGADIHLDSFVSAI
TKDGEGFAIKGGGEGTYDKVILAVPAPTAAVLLRDLAPTAAPHLRAIKLASSAVVGMRFDSSEGLPDNSGVLVAVNEPGI
TAKAFTFSSKKWPHLEARGGALVRASFGRLGDEASARMDEDLLVDAALDDLLTITGFDGRAAGLGEIFVQRWFGGLPAYG
VDHIAAVSAARAEIAAVPGVEAIGAWAGGVGVPAVIADAQAAVHRLLG

Sequences:

>Translated_448_residues
MRFAIIGAGLAGLTAAYEIHKADPTAQIDVLEAGERIGGKLFTVPFASGPTDIGAEAFLAARSDAVEFFTELGLADSLVS
PSAAKSQYFAGGALHAFPAGGVMGIPSNPPAGAQDTAFDWTPGHDISVGALVRRQYGDEIVDTVVSSLLGGVYSSTADDL
GVRASVPALAAALDQLAEAGEPVTLSAAVKAVEAQREAAKTTSETRPVFQTFKGGYAELYEALAEQCGADIHLDSFVSAI
TKDGEGFAIKGGGEGTYDKVILAVPAPTAAVLLRDLAPTAAPHLRAIKLASSAVVGMRFDSSEGLPDNSGVLVAVNEPGI
TAKAFTFSSKKWPHLEARGGALVRASFGRLGDEASARMDEDLLVDAALDDLLTITGFDGRAAGLGEIFVQRWFGGLPAYG
VDHIAAVSAARAEIAAVPGVEAIGAWAGGVGVPAVIADAQAAVHRLLG
>Mature_448_residues
MRFAIIGAGLAGLTAAYEIHKADPTAQIDVLEAGERIGGKLFTVPFASGPTDIGAEAFLAARSDAVEFFTELGLADSLVS
PSAAKSQYFAGGALHAFPAGGVMGIPSNPPAGAQDTAFDWTPGHDISVGALVRRQYGDEIVDTVVSSLLGGVYSSTADDL
GVRASVPALAAALDQLAEAGEPVTLSAAVKAVEAQREAAKTTSETRPVFQTFKGGYAELYEALAEQCGADIHLDSFVSAI
TKDGEGFAIKGGGEGTYDKVILAVPAPTAAVLLRDLAPTAAPHLRAIKLASSAVVGMRFDSSEGLPDNSGVLVAVNEPGI
TAKAFTFSSKKWPHLEARGGALVRASFGRLGDEASARMDEDLLVDAALDDLLTITGFDGRAAGLGEIFVQRWFGGLPAYG
VDHIAAVSAARAEIAAVPGVEAIGAWAGGVGVPAVIADAQAAVHRLLG

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

Organism=Homo sapiens, GI170650615, Length=347, Percent_Identity=26.8011527377522, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4506001, Length=347, Percent_Identity=26.8011527377522, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 45709; Mature: 45709

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFAIIGAGLAGLTAAYEIHKADPTAQIDVLEAGERIGGKLFTVPFASGPTDIGAEAFLA
CEEEEEECCHHHHHHHHEEECCCCCCEEEHHHHHHHHCCEEEEEECCCCCCCCCHHHHHH
ARSDAVEFFTELGLADSLVSPSAAKSQYFAGGALHAFPAGGVMGIPSNPPAGAQDTAFDW
HHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCEEECCCCCEECCCCCCCCCCCCCCCCC
TPGHDISVGALVRRQYGDEIVDTVVSSLLGGVYSSTADDLGVRASVPALAAALDQLAEAG
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCC
EPVTLSAAVKAVEAQREAAKTTSETRPVFQTFKGGYAELYEALAEQCGADIHLDSFVSAI
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHH
TKDGEGFAIKGGGEGTYDKVILAVPAPTAAVLLRDLAPTAAPHLRAIKLASSAVVGMRFD
HCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEEEC
SSEGLPDNSGVLVAVNEPGITAKAFTFSSKKWPHLEARGGALVRASFGRLGDEASARMDE
CCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCEECCCCEEEEEHHHCCCCHHHHCCCH
DLLVDAALDDLLTITGFDGRAAGLGEIFVQRWFGGLPAYGVDHIAAVSAARAEIAAVPGV
HHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCH
EAIGAWAGGVGVPAVIADAQAAVHRLLG
HHHHHCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFAIIGAGLAGLTAAYEIHKADPTAQIDVLEAGERIGGKLFTVPFASGPTDIGAEAFLA
CEEEEEECCHHHHHHHHEEECCCCCCEEEHHHHHHHHCCEEEEEECCCCCCCCCHHHHHH
ARSDAVEFFTELGLADSLVSPSAAKSQYFAGGALHAFPAGGVMGIPSNPPAGAQDTAFDW
HHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCEEECCCCCEECCCCCCCCCCCCCCCCC
TPGHDISVGALVRRQYGDEIVDTVVSSLLGGVYSSTADDLGVRASVPALAAALDQLAEAG
CCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCC
EPVTLSAAVKAVEAQREAAKTTSETRPVFQTFKGGYAELYEALAEQCGADIHLDSFVSAI
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHH
TKDGEGFAIKGGGEGTYDKVILAVPAPTAAVLLRDLAPTAAPHLRAIKLASSAVVGMRFD
HCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEEEC
SSEGLPDNSGVLVAVNEPGITAKAFTFSSKKWPHLEARGGALVRASFGRLGDEASARMDE
CCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCEECCCCEEEEEHHHCCCCHHHHCCCH
DLLVDAALDDLLTITGFDGRAAGLGEIFVQRWFGGLPAYGVDHIAAVSAARAEIAAVPGV
HHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCH
EAIGAWAGGVGVPAVIADAQAAVHRLLG
HHHHHCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]