Click here to switch to the map view.

The map label for this gene is uxuA [H]

Identifier: 138895420

GI number: 138895420

Start: 1865390

End: 1866505

Strand: Reverse

Name: uxuA [H]

Synonym: GTNG_1764

Alternate gene names: 138895420

Gene position: 1866505-1865390 (Counterclockwise)

Preceding gene: 138895421

Following gene: 138895419

Centisome position: 52.57

GC content: 44.18

Gene sequence:

>1116_bases
ATGAAAATGACATTTCGCTGGTTTGGTAAGGATTATGATACGGTTTCATTGGATCATATCCGTCAAATTCCAGGAGTAGA
AGGAATTGTAGGAGCTTTGTATCACATTCCGGTCGGGGAAGTATGGCCACTAGAAGACATATTGGAATTAAAGCGGCAAG
TGAATAAGAACGGATTTCACCTCGAGGTGATCGAGAGTGTCAACGTTCATGAAGATATTAAACTTGGCCTGCCTTCGCGG
GAACGGTATATCGAAAACTATAAACAAACGATTCGCAACTTGTCGAAAGCCGGAGTGAAAGTGATCTGTTATAATTTTAT
GCCGATTTTCGACTGGACTCGTTCTGATTTGGCGAAAAGACGGCCTGACGGTTCAACAGTGCTTGCTTATGAGAAGCAAA
AAGTTGAACAAATTGACCCTGAGGAAATGATCCGCCGCATTGAAAACGGAGCGAATGGTTTTTTGCTTCCGGGATGGGAG
CCGGAACGATTGAAAACGATTAAACCGCTTTTCGCTCTATATAAAGGAGTAACGGAGGATGATTTGCTTGACCATTTGCG
TTACTTTTTGGAGCAAATCGTTCCGGTCGCGGAGGAATGTGGCATCCAAATGGCGATTCACCCTGACGATCCACCGTGGT
CAGTGTTTGGACTGCCACGGATTGTAACAAATAAAGAAAACTTGAAGAAAATTATCAATATGGTCAATAGCCCAGCGAAC
GGACTGACGCTATGCTCTGGCTCACTCGGTGCGAATCCGGACAACGATATTCCAGACATCTTTCGTTATTTTTTGCGTAT
GGGGAGAGTGCCGTTTGTCCATGTACGCAATATTGAAATTCATACGAATGGCGATTTTGAGGAAACATCCCATCGCAGCT
GTGATGGTTCATTGAATATATGTGAAATCGTAAAAGTGTTACACGAATCGGATTTTCAAGGATACATTCGCCCAGACCAC
GGCCGGATGATTTGGGGGGAACAAGCTCGCCCGGGCTATGGACTGTATGATCGGGCGCTTGGCATTATGTACTTGTTAGG
TATTTGGGATAGTTTGGAAAATGAGAAAAGAAAACGGGAAGGAGACAAAACATGCTCCCAATCCATCCAAGTTTAA

Upstream 100 bases:

>100_bases
CGCAAGATTATGCCTTTTTAGGGAAAATTGTCCAAGATATATGTTATTTCAATGCGAAACAGTATTTTGATTTATCGTGA
ACGGGGGAGGTGAGACCACA

Downstream 100 bases:

>100_bases
AAGGAAAAGTAGCGGTCGTCACAGGTGGAGGTGGGGTGCTATGCAGCTGCATGGCAAAAGAGCTTGCCCGCCAAGGGATG
AAAGTAGTGATTTTAAATCG

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MKMTFRWFGKDYDTVSLDHIRQIPGVEGIVGALYHIPVGEVWPLEDILELKRQVNKNGFHLEVIESVNVHEDIKLGLPSR
ERYIENYKQTIRNLSKAGVKVICYNFMPIFDWTRSDLAKRRPDGSTVLAYEKQKVEQIDPEEMIRRIENGANGFLLPGWE
PERLKTIKPLFALYKGVTEDDLLDHLRYFLEQIVPVAEECGIQMAIHPDDPPWSVFGLPRIVTNKENLKKIINMVNSPAN
GLTLCSGSLGANPDNDIPDIFRYFLRMGRVPFVHVRNIEIHTNGDFEETSHRSCDGSLNICEIVKVLHESDFQGYIRPDH
GRMIWGEQARPGYGLYDRALGIMYLLGIWDSLENEKRKREGDKTCSQSIQV

Sequences:

>Translated_371_residues
MKMTFRWFGKDYDTVSLDHIRQIPGVEGIVGALYHIPVGEVWPLEDILELKRQVNKNGFHLEVIESVNVHEDIKLGLPSR
ERYIENYKQTIRNLSKAGVKVICYNFMPIFDWTRSDLAKRRPDGSTVLAYEKQKVEQIDPEEMIRRIENGANGFLLPGWE
PERLKTIKPLFALYKGVTEDDLLDHLRYFLEQIVPVAEECGIQMAIHPDDPPWSVFGLPRIVTNKENLKKIINMVNSPAN
GLTLCSGSLGANPDNDIPDIFRYFLRMGRVPFVHVRNIEIHTNGDFEETSHRSCDGSLNICEIVKVLHESDFQGYIRPDH
GRMIWGEQARPGYGLYDRALGIMYLLGIWDSLENEKRKREGDKTCSQSIQV
>Mature_371_residues
MKMTFRWFGKDYDTVSLDHIRQIPGVEGIVGALYHIPVGEVWPLEDILELKRQVNKNGFHLEVIESVNVHEDIKLGLPSR
ERYIENYKQTIRNLSKAGVKVICYNFMPIFDWTRSDLAKRRPDGSTVLAYEKQKVEQIDPEEMIRRIENGANGFLLPGWE
PERLKTIKPLFALYKGVTEDDLLDHLRYFLEQIVPVAEECGIQMAIHPDDPPWSVFGLPRIVTNKENLKKIINMVNSPAN
GLTLCSGSLGANPDNDIPDIFRYFLRMGRVPFVHVRNIEIHTNGDFEETSHRSCDGSLNICEIVKVLHESDFQGYIRPDH
GRMIWGEQARPGYGLYDRALGIMYLLGIWDSLENEKRKREGDKTCSQSIQV

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=391, Percent_Identity=36.3171355498721, Blast_Score=242, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 42695; Mature: 42695

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMTFRWFGKDYDTVSLDHIRQIPGVEGIVGALYHIPVGEVWPLEDILELKRQVNKNGFH
CCCEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCE
LEVIESVNVHEDIKLGLPSRERYIENYKQTIRNLSKAGVKVICYNFMPIFDWTRSDLAKR
EEEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHCCHHHHHHHH
RPDGSTVLAYEKQKVEQIDPEEMIRRIENGANGFLLPGWEPERLKTIKPLFALYKGVTED
CCCCCEEEEECHHHHHCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHCCCCHH
DLLDHLRYFLEQIVPVAEECGIQMAIHPDDPPWSVFGLPRIVTNKENLKKIINMVNSPAN
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHCCHHHHHHHHHHHCCCCC
GLTLCSGSLGANPDNDIPDIFRYFLRMGRVPFVHVRNIEIHTNGDFEETSHRSCDGSLNI
CEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCH
CEIVKVLHESDFQGYIRPDHGRMIWGEQARPGYGLYDRALGIMYLLGIWDSLENEKRKRE
HHHHHHHHHCCCCCCEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GDKTCSQSIQV
HHHHHHHCCCC
>Mature Secondary Structure
MKMTFRWFGKDYDTVSLDHIRQIPGVEGIVGALYHIPVGEVWPLEDILELKRQVNKNGFH
CCCEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCE
LEVIESVNVHEDIKLGLPSRERYIENYKQTIRNLSKAGVKVICYNFMPIFDWTRSDLAKR
EEEECCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHCCHHHHHHHH
RPDGSTVLAYEKQKVEQIDPEEMIRRIENGANGFLLPGWEPERLKTIKPLFALYKGVTED
CCCCCEEEEECHHHHHCCCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHCCCCHH
DLLDHLRYFLEQIVPVAEECGIQMAIHPDDPPWSVFGLPRIVTNKENLKKIINMVNSPAN
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHCCHHHHHHHHHHHCCCCC
GLTLCSGSLGANPDNDIPDIFRYFLRMGRVPFVHVRNIEIHTNGDFEETSHRSCDGSLNI
CEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCH
CEIVKVLHESDFQGYIRPDHGRMIWGEQARPGYGLYDRALGIMYLLGIWDSLENEKRKRE
HHHHHHHHHCCCCCCEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GDKTCSQSIQV
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10368143 [H]