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The map label for this gene is gmuR [H]

Identifier: 138895402

GI number: 138895402

Start: 1846668

End: 1847390

Strand: Reverse

Name: gmuR [H]

Synonym: GTNG_1746

Alternate gene names: 138895402

Gene position: 1847390-1846668 (Counterclockwise)

Preceding gene: 138895403

Following gene: 138895400

Centisome position: 52.03

GC content: 46.61

Gene sequence:

>723_bases
ATGAAAATGATGCCAAAGTATGAACAAATTTCAAATGAAATACGTAGGCGAATTAAAGAGGGGATGTATTCTCTAGACGA
GCCGATTCCTGATGAAATCTCGCTCGCTGAGGAGTTTGGCTGCAGCCGGATGACTGTAAAACGAGCACTTGATGTGCTTG
TGTCCGAAGGGCTGTTGTATCGAAAGCGTGGTCATGGCACATTTATTGTGAAATCCGCGATGCTTAACGGACTAGTGAAC
GTTGTCAGCAACGAAACGCTCGGCTTAACGAGCTTATTGGAAGGACGAAAGGTGGCAAGCCATATTATCACCTTTGAAGT
GTTGTTTCCCACTGATGAGGTGGCTTCGCATTTGTGTATTGATGCAAACACACCGGTGTATCACTTAATCCGACTGCGCA
AGGTCGATGGGGAACCGTACGTCATTGAACGGACGTATATGCCTGTCCATTTGATTTCGGGACTCAATGAAACGGTGCTT
CATGGCTCGATTTATCATTACATTACTCATGAGCTTGGGTTAACTATTGCCGGATCGCACCGCAAGATTCGTGCCGATAA
ACCGAACGAGCTTGATCGGCAATACTTGCAATGCGCGCCCGATGATCCTGTGTTGGAATTGGAGCAGGTTGGCTTTTTAA
ACAACGGCAAACCGTTTGAATATTCGTTTTCCCGCCATCGGTATGATAAGTTCGTGTTTGTCACCGTCAGCACCCGTCGC
TAA

Upstream 100 bases:

>100_bases
GGATGAGGCAGCGTGAAAAGAGGAATGAGGGGGAAAGTCACACTGGCTATTGTGTAAACAGATGATTGTTCGTACAATGA
AGATAAGATAATGGTGAGGG

Downstream 100 bases:

>100_bases
AAGGCGTCTGCCCAGCTGCTTTGAGGCAGGCGCCTTTTTCTATATATGGAAGAGGTGGTGAAGCCAAAGCGGTTACGACT
TTTGCCGGGACGGCACGGCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKMMPKYEQISNEIRRRIKEGMYSLDEPIPDEISLAEEFGCSRMTVKRALDVLVSEGLLYRKRGHGTFIVKSAMLNGLVN
VVSNETLGLTSLLEGRKVASHIITFEVLFPTDEVASHLCIDANTPVYHLIRLRKVDGEPYVIERTYMPVHLISGLNETVL
HGSIYHYITHELGLTIAGSHRKIRADKPNELDRQYLQCAPDDPVLELEQVGFLNNGKPFEYSFSRHRYDKFVFVTVSTRR

Sequences:

>Translated_240_residues
MKMMPKYEQISNEIRRRIKEGMYSLDEPIPDEISLAEEFGCSRMTVKRALDVLVSEGLLYRKRGHGTFIVKSAMLNGLVN
VVSNETLGLTSLLEGRKVASHIITFEVLFPTDEVASHLCIDANTPVYHLIRLRKVDGEPYVIERTYMPVHLISGLNETVL
HGSIYHYITHELGLTIAGSHRKIRADKPNELDRQYLQCAPDDPVLELEQVGFLNNGKPFEYSFSRHRYDKFVFVTVSTRR
>Mature_240_residues
MKMMPKYEQISNEIRRRIKEGMYSLDEPIPDEISLAEEFGCSRMTVKRALDVLVSEGLLYRKRGHGTFIVKSAMLNGLVN
VVSNETLGLTSLLEGRKVASHIITFEVLFPTDEVASHLCIDANTPVYHLIRLRKVDGEPYVIERTYMPVHLISGLNETVL
HGSIYHYITHELGLTIAGSHRKIRADKPNELDRQYLQCAPDDPVLELEQVGFLNNGKPFEYSFSRHRYDKFVFVTVSTRR

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790118, Length=222, Percent_Identity=32.4324324324324, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786950, Length=241, Percent_Identity=31.1203319502075, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788418, Length=232, Percent_Identity=28.448275862069, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082252, Length=217, Percent_Identity=24.4239631336406, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27481; Mature: 27481

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMMPKYEQISNEIRRRIKEGMYSLDEPIPDEISLAEEFGCSRMTVKRALDVLVSEGLLY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCEEE
RKRGHGTFIVKSAMLNGLVNVVSNETLGLTSLLEGRKVASHIITFEVLFPTDEVASHLCI
EECCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEEEECCHHHHHHEEE
DANTPVYHLIRLRKVDGEPYVIERTYMPVHLISGLNETVLHGSIYHYITHELGLTIAGSH
CCCCCHHHHHEEEECCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHCEEEECCC
RKIRADKPNELDRQYLQCAPDDPVLELEQVGFLNNGKPFEYSFSRHRYDKFVFVTVSTRR
CEECCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCEECHHHCCCCEEEEEEEECCC
>Mature Secondary Structure
MKMMPKYEQISNEIRRRIKEGMYSLDEPIPDEISLAEEFGCSRMTVKRALDVLVSEGLLY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCEEE
RKRGHGTFIVKSAMLNGLVNVVSNETLGLTSLLEGRKVASHIITFEVLFPTDEVASHLCI
EECCCCEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEEEECCHHHHHHEEE
DANTPVYHLIRLRKVDGEPYVIERTYMPVHLISGLNETVLHGSIYHYITHELGLTIAGSH
CCCCCHHHHHEEEECCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHHHHHHHCEEEECCC
RKIRADKPNELDRQYLQCAPDDPVLELEQVGFLNNGKPFEYSFSRHRYDKFVFVTVSTRR
CEECCCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCEECHHHCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]