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The map label for this gene is cbiL [H]

Identifier: 138895344

GI number: 138895344

Start: 1778444

End: 1779145

Strand: Reverse

Name: cbiL [H]

Synonym: GTNG_1688

Alternate gene names: 138895344

Gene position: 1779145-1778444 (Counterclockwise)

Preceding gene: 138895345

Following gene: 138895343

Centisome position: 50.11

GC content: 56.27

Gene sequence:

>702_bases
ATGACGGGAACATTATATGGCATCGGCGTGGGCCCAGGCGATCCGGAGCTGATGACTGTCAAGGCGTACCGCCGCCTAAA
AGAGGCGGAGGTGATCGCCTATCCAAAAAAAGGGCGGCAAAGCAAAAGCTATGCCGAACAAATTATCGACGCGTATTTTG
CGCCGGAGGAAAAACGCCGGCTTGGGCTTCATTTTCCGATGACAAAAGACGTGGCCGTGCTTGAACCAAAATGGAACGAA
GCAGCCGACGCCATTTGGGCGGAACTGTCGGCTGGGCGCGATGTGGCGTTTGTCACCGAAGGCGATCCGCTGTTGTACAG
CACGTTCATCCATTTGATGCATGTGATGGAGCGACGCTATCCAGACGCGCCGATCGAAGTCGTCCCCGGCGTCAGCTCGG
CGAACGCCGCCGCCGCCCGGCTTCGCCTGCCGCTGGCGGACGGCGATGAGCAAGTGGCGATCGTGCCGGCGCGTGACGAC
TATGAAGCGATGAAAGCCGCGATTCTTGCACATGATTGTGTCATCTTTTTTAAAGTAGCAAAAGTGATCGACTTGATGAT
CCGCCTCCTGCGCGAGCTCGATTTGCTTCATCGGGCGGCAGTGGTGACGAAAGTGACGTCAAGGGAAGAAGTCATTTGGG
ACGTTGAGCGGCTCGAAGGGGCAGAACTCGAATATTTGACATTGCTGGTGGTGAGAAAGTGA

Upstream 100 bases:

>100_bases
CGCTCGCGCAAGTGTCGCGAAGCAAGCCGATTTTGAACTTGACGCGCTTTGAGGCGCTCAATCCGGTGTACATCATAGCC
GCGAAGCGGGAGGGAGAGAA

Downstream 100 bases:

>100_bases
AGCTGTATATCATCGGAGCGGGGCCGGGAGCGCCGGATTTGATCACCGTTCGAGGAGCGGAGCTGTTGGCCGCGGCGGAC
GCCATTTTTTACACCGACTC

Product: precorrin-2 methylase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTGTLYGIGVGPGDPELMTVKAYRRLKEAEVIAYPKKGRQSKSYAEQIIDAYFAPEEKRRLGLHFPMTKDVAVLEPKWNE
AADAIWAELSAGRDVAFVTEGDPLLYSTFIHLMHVMERRYPDAPIEVVPGVSSANAAAARLRLPLADGDEQVAIVPARDD
YEAMKAAILAHDCVIFFKVAKVIDLMIRLLRELDLLHRAAVVTKVTSREEVIWDVERLEGAELEYLTLLVVRK

Sequences:

>Translated_233_residues
MTGTLYGIGVGPGDPELMTVKAYRRLKEAEVIAYPKKGRQSKSYAEQIIDAYFAPEEKRRLGLHFPMTKDVAVLEPKWNE
AADAIWAELSAGRDVAFVTEGDPLLYSTFIHLMHVMERRYPDAPIEVVPGVSSANAAAARLRLPLADGDEQVAIVPARDD
YEAMKAAILAHDCVIFFKVAKVIDLMIRLLRELDLLHRAAVVTKVTSREEVIWDVERLEGAELEYLTLLVVRK
>Mature_232_residues
TGTLYGIGVGPGDPELMTVKAYRRLKEAEVIAYPKKGRQSKSYAEQIIDAYFAPEEKRRLGLHFPMTKDVAVLEPKWNEA
ADAIWAELSAGRDVAFVTEGDPLLYSTFIHLMHVMERRYPDAPIEVVPGVSSANAAAARLRLPLADGDEQVAIVPARDDY
EAMKAAILAHDCVIFFKVAKVIDLMIRLLRELDLLHRAAVVTKVTSREEVIWDVERLEGAELEYLTLLVVRK

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 26090; Mature: 25958

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGTLYGIGVGPGDPELMTVKAYRRLKEAEVIAYPKKGRQSKSYAEQIIDAYFAPEEKRR
CCCEEEEEECCCCCCCEEEHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCHHHH
LGLHFPMTKDVAVLEPKWNEAADAIWAELSAGRDVAFVTEGDPLLYSTFIHLMHVMERRY
CCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHC
PDAPIEVVPGVSSANAAAARLRLPLADGDEQVAIVPARDDYEAMKAAILAHDCVIFFKVA
CCCCEEEECCCCCCCHHHHEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KVIDLMIRLLRELDLLHRAAVVTKVTSREEVIWDVERLEGAELEYLTLLVVRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEEECC
>Mature Secondary Structure 
TGTLYGIGVGPGDPELMTVKAYRRLKEAEVIAYPKKGRQSKSYAEQIIDAYFAPEEKRR
CCEEEEEECCCCCCCEEEHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCHHHH
LGLHFPMTKDVAVLEPKWNEAADAIWAELSAGRDVAFVTEGDPLLYSTFIHLMHVMERRY
CCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHC
PDAPIEVVPGVSSANAAAARLRLPLADGDEQVAIVPARDDYEAMKAAILAHDCVIFFKVA
CCCCEEEECCCCCCCHHHHEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KVIDLMIRLLRELDLLHRAAVVTKVTSREEVIWDVERLEGAELEYLTLLVVRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]