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The map label for this gene is cbiET [H]

Identifier: 138895345

GI number: 138895345

Start: 1779142

End: 1780347

Strand: Reverse

Name: cbiET [H]

Synonym: GTNG_1689

Alternate gene names: 138895345

Gene position: 1780347-1779142 (Counterclockwise)

Preceding gene: 138895346

Following gene: 138895344

Centisome position: 50.15

GC content: 58.04

Gene sequence:

>1206_bases
ATGGGGACGATGAAGTTGATCGGTGTGGGTGCTGATGGGCAAGCAAGTCTTCCTGAGCTGTATCGACGCTGGATTGATGA
AAGCGAGCTGCTTGTCGGCGGCGAACGGCAGCTGGCGATGTTTCCTGAATACAAAGGAGAAACGATCATCATCCGCCGCG
GACTGGCGGAGCTGGTGGAGCGGCTCCGCCATGAGACGCGCAACACGGTCGTGCTTGCTTCCGGCGATCCGCTCTTTTAC
GGCATCGGCAGCTATTTGGCCGGCAAATTGCCGATCGACGTGTATCCGGCCGTCAGCTCAGTGCAATGGGCGTTTGCGAA
AATGGGGGAGTCTTGGCAAGATGCCGCATTTGTCAGCGCCCATGGCCGCCCGCTCACCGGCCTCGTGCAACGGATCGACG
GGCGGCGCAAAGTCGCCATCTTAACCGATGAGACGAACTCGCCGGCCGTCATCGCCCGCTATTTGCTCGAGTACGGCATG
ACGGAATATGAGGCGTTTGTCGGCGAGGAGCTCGGCGGCCCGAACGAGCGCTGCCGCTTGTTTTCGTTGGAAGAGATGGC
GGAAGCCGAGTTTCTTCCATTAAATATAGTCATTTTGCGGCAGACAGCGCCAAGCCCGGTTTGGCCGTTCGGCATTGAGG
ATGACGAGTTTTTTCAGCGCAAGCCGGACAAAGGATTGATTACGAAAAAAGAAATCCGAGTTTTAAGTCTAAGCGCCTTG
CGCTTGCGCCCGGACAGCGTCGTCTGGGATATTGGAACGTGCACCGGTTCGGTGGCGATTGAAGCGGCGAAAATCGCCCG
CGACGGCGCCGTGTTTGCGATTGAAAAAAATGAACAAGATATCGAACTTTGCCGGCAAAACTTGCGCAAATTCCGCGTCG
ATATCACACTTGTGCACGGCAGGGCGCCCGATCGGCTCGACGAATTTGCCGACCCGGACGCCATCTTTATCGGCGGCACG
TCAGGGGCGATGGCGCCATTGCTGGATGTGTGCTGCCGCCGCTTGAAACGAAACGGGCGCATCGTCATCAATGCGGCGAC
GATCGAGACGCTGGCCGAAGCGAGCCGCGAGCTCGGCGAACGCGGGTTTCATGTCGATATCACGCTCGCGCAAGTGTCGC
GAAGCAAGCCGATTTTGAACTTGACGCGCTTTGAGGCGCTCAATCCGGTGTACATCATAGCCGCGAAGCGGGAGGGAGAG
AAATGA

Upstream 100 bases:

>100_bases
TGCTGCCAGGCGGCGCTTCACGAAGTGGGAGGCGGTCTGACGGTGGCGACGTCCATTTACACAATGAACGGACAACAATT
AGGAAAGGCGGTGCAGACCG

Downstream 100 bases:

>100_bases
CGGGAACATTATATGGCATCGGCGTGGGCCCAGGCGATCCGGAGCTGATGACTGTCAAGGCGTACCGCCGCCTAAAAGAG
GCGGAGGTGATCGCCTATCC

Product: cobalamin biosynthesis protein CbiET

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MGTMKLIGVGADGQASLPELYRRWIDESELLVGGERQLAMFPEYKGETIIIRRGLAELVERLRHETRNTVVLASGDPLFY
GIGSYLAGKLPIDVYPAVSSVQWAFAKMGESWQDAAFVSAHGRPLTGLVQRIDGRRKVAILTDETNSPAVIARYLLEYGM
TEYEAFVGEELGGPNERCRLFSLEEMAEAEFLPLNIVILRQTAPSPVWPFGIEDDEFFQRKPDKGLITKKEIRVLSLSAL
RLRPDSVVWDIGTCTGSVAIEAAKIARDGAVFAIEKNEQDIELCRQNLRKFRVDITLVHGRAPDRLDEFADPDAIFIGGT
SGAMAPLLDVCCRRLKRNGRIVINAATIETLAEASRELGERGFHVDITLAQVSRSKPILNLTRFEALNPVYIIAAKREGE
K

Sequences:

>Translated_401_residues
MGTMKLIGVGADGQASLPELYRRWIDESELLVGGERQLAMFPEYKGETIIIRRGLAELVERLRHETRNTVVLASGDPLFY
GIGSYLAGKLPIDVYPAVSSVQWAFAKMGESWQDAAFVSAHGRPLTGLVQRIDGRRKVAILTDETNSPAVIARYLLEYGM
TEYEAFVGEELGGPNERCRLFSLEEMAEAEFLPLNIVILRQTAPSPVWPFGIEDDEFFQRKPDKGLITKKEIRVLSLSAL
RLRPDSVVWDIGTCTGSVAIEAAKIARDGAVFAIEKNEQDIELCRQNLRKFRVDITLVHGRAPDRLDEFADPDAIFIGGT
SGAMAPLLDVCCRRLKRNGRIVINAATIETLAEASRELGERGFHVDITLAQVSRSKPILNLTRFEALNPVYIIAAKREGE
K
>Mature_400_residues
GTMKLIGVGADGQASLPELYRRWIDESELLVGGERQLAMFPEYKGETIIIRRGLAELVERLRHETRNTVVLASGDPLFYG
IGSYLAGKLPIDVYPAVSSVQWAFAKMGESWQDAAFVSAHGRPLTGLVQRIDGRRKVAILTDETNSPAVIARYLLEYGMT
EYEAFVGEELGGPNERCRLFSLEEMAEAEFLPLNIVILRQTAPSPVWPFGIEDDEFFQRKPDKGLITKKEIRVLSLSALR
LRPDSVVWDIGTCTGSVAIEAAKIARDGAVFAIEKNEQDIELCRQNLRKFRVDITLVHGRAPDRLDEFADPDAIFIGGTS
GAMAPLLDVCCRRLKRNGRIVINAATIETLAEASRELGERGFHVDITLAQVSRSKPILNLTRFEALNPVYIIAAKREGEK

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 44559; Mature: 44428

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTMKLIGVGADGQASLPELYRRWIDESELLVGGERQLAMFPEYKGETIIIRRGLAELVE
CCCEEEEEECCCCCCCHHHHHHHHCCCCCEEECCCCCEEECCCCCCCEEEEECCHHHHHH
RLRHETRNTVVLASGDPLFYGIGSYLAGKLPIDVYPAVSSVQWAFAKMGESWQDAAFVSA
HHHHCCCCEEEEECCCCEEEECHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCEEEEC
HGRPLTGLVQRIDGRRKVAILTDETNSPAVIARYLLEYGMTEYEAFVGEELGGPNERCRL
CCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHEEE
FSLEEMAEAEFLPLNIVILRQTAPSPVWPFGIEDDEFFQRKPDKGLITKKEIRVLSLSAL
EEHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCEEHHHEEEEEEEEE
RLRPDSVVWDIGTCTGSVAIEAAKIARDGAVFAIEKNEQDIELCRQNLRKFRVDITLVHG
EECCCCEEEEECCCCCCCEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHEEEEEEEEEC
RAPDRLDEFADPDAIFIGGTSGAMAPLLDVCCRRLKRNGRIVINAATIETLAEASRELGE
CCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHC
RGFHVDITLAQVSRSKPILNLTRFEALNPVYIIAAKREGEK
CCCEEEEEEEECCCCCCCEEEHHHCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
GTMKLIGVGADGQASLPELYRRWIDESELLVGGERQLAMFPEYKGETIIIRRGLAELVE
CCEEEEEECCCCCCCHHHHHHHHCCCCCEEECCCCCEEECCCCCCCEEEEECCHHHHHH
RLRHETRNTVVLASGDPLFYGIGSYLAGKLPIDVYPAVSSVQWAFAKMGESWQDAAFVSA
HHHHCCCCEEEEECCCCEEEECHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCEEEEC
HGRPLTGLVQRIDGRRKVAILTDETNSPAVIARYLLEYGMTEYEAFVGEELGGPNERCRL
CCCCHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHEEE
FSLEEMAEAEFLPLNIVILRQTAPSPVWPFGIEDDEFFQRKPDKGLITKKEIRVLSLSAL
EEHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHCCCCCCCEEHHHEEEEEEEEE
RLRPDSVVWDIGTCTGSVAIEAAKIARDGAVFAIEKNEQDIELCRQNLRKFRVDITLVHG
EECCCCEEEEECCCCCCCEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHEEEEEEEEEC
RAPDRLDEFADPDAIFIGGTSGAMAPLLDVCCRRLKRNGRIVINAATIETLAEASRELGE
CCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHC
RGFHVDITLAQVSRSKPILNLTRFEALNPVYIIAAKREGEK
CCCEEEEEEEECCCCCCCEEEHHHCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]