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The map label for this gene is hmp [H]

Identifier: 138895290

GI number: 138895290

Start: 1720693

End: 1721928

Strand: Reverse

Name: hmp [H]

Synonym: GTNG_1634

Alternate gene names: 138895290

Gene position: 1721928-1720693 (Counterclockwise)

Preceding gene: 138895294

Following gene: 138895289

Centisome position: 48.5

GC content: 50.57

Gene sequence:

>1236_bases
ATGGCTACGAGCACAACTTTACACCCAAAAACGATCGAAATTGTCAAATCAACAGTACCGGTATTGGAGAAGCATGGAGA
ACAGATTACAAAACGGTTTTATGAGCTCATGTTTTCCAATCATCCAGAGTTGCTGAACGTGTTTAACCATGCCCACCAAA
AACAAGGGCGGCAGCCACGTGCTTTGGCTGCAGCAGTCTACGCAGCGGCGCGCTATATCGATCAGCTCGATGCCATCTTG
CCGGTCGTACGGCAAATCGGCCATAAACACCGGAGTTTAGGCATCAAACCGGAACAATATCCGATCGTCGGAAAGCATTT
GCTGCTGGCGATCAAAGACGTCCTTGGCGATGCCGCCACTGACGAAGTAATTGCCGCGTGGGCGGAAGCGTATGAAGTCA
TTGCTGACGTGTTCATTCAAGTCGAGCAGGAGCTCTACGATGAAGCAGCGGCCAAACGCGGCGGCTGGCGTGATTTTCGT
CGCTTTGTCGTCGCCAAAAAAGTGAAAGAAAGCGACGTCATCACCTCGTTTTATCTCAAATCGGAAGACGGCGACGCCAT
TAGCGACTATTTGCCAGGCCAATACGTCAGCGTAAAAATGTCAATACCAGGCGAAACGTACACACACATCCGGCAGTACA
GCTTATCGGATGCACCAGGAAAAGGGTATTACCGCATCAGCGTCAAACGGGAAGCAGCGACGGCTGACAAACCGGCCGGC
ATTGTTTCGAATTACTTGCATGATCATATCCAAGAAGGGGATGTGCTTGAATTAAGCGCCCCAGCCGGTGACTTTACGCT
TGATTTGGCAAAAGAAACGCCGGTCGTCTTCATTAGCGGCGGCGTTGGCATCACTCCGCTTTTGAGCATGGCAAATACGT
TGGCCATTCGGCAGCCTAACCGCCCGGTTACGTTCCTGCAAGCTGCTCTCAATGGCCGCGTACAGGCGTTTGACCAAGAG
TTGCAGACCTTAGCTAAAAATCCAGTATTTTCTTATCACATTTGTTACGAGTCGCCGTCAGATGAAGATCGAAAACACCC
GCACTTCAGCAAAGAAGGGCGGATCGATTTGGAATGGATGCAAACGGTCATTCCGTCCAAAGACGCTGACTTTTACTTCT
GTGGCCCTGTTCCGTTCATGAAAACGGTCTATCGCGCCCTGAAGCAATGGGGCGTGCCTGAGGAACGCATCCATTACGAA
TTTTTCGGTCCAGCCGGCGATTTAACAAAAGACTAA

Upstream 100 bases:

>100_bases
ACAATTTGTTAAAGATGTATTTGAAATATTGCTTTTCATTATCGCTCATGGTTGAATAAAAGATGTATTTTAAATACATG
TTTTGTGAGGGGATGGAACA

Downstream 100 bases:

>100_bases
TCAATGGCCGCTTATCAAAAAGGCATCTCCCAGATAGGGAGGTGCCTTTTGTTATAGAGAACATCCGCGCTTCCCTGTTG
GCAAGTCCGCCAATTTTTTG

Product: nitric oxide dioxygenase

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MATSTTLHPKTIEIVKSTVPVLEKHGEQITKRFYELMFSNHPELLNVFNHAHQKQGRQPRALAAAVYAAARYIDQLDAIL
PVVRQIGHKHRSLGIKPEQYPIVGKHLLLAIKDVLGDAATDEVIAAWAEAYEVIADVFIQVEQELYDEAAAKRGGWRDFR
RFVVAKKVKESDVITSFYLKSEDGDAISDYLPGQYVSVKMSIPGETYTHIRQYSLSDAPGKGYYRISVKREAATADKPAG
IVSNYLHDHIQEGDVLELSAPAGDFTLDLAKETPVVFISGGVGITPLLSMANTLAIRQPNRPVTFLQAALNGRVQAFDQE
LQTLAKNPVFSYHICYESPSDEDRKHPHFSKEGRIDLEWMQTVIPSKDADFYFCGPVPFMKTVYRALKQWGVPEERIHYE
FFGPAGDLTKD

Sequences:

>Translated_411_residues
MATSTTLHPKTIEIVKSTVPVLEKHGEQITKRFYELMFSNHPELLNVFNHAHQKQGRQPRALAAAVYAAARYIDQLDAIL
PVVRQIGHKHRSLGIKPEQYPIVGKHLLLAIKDVLGDAATDEVIAAWAEAYEVIADVFIQVEQELYDEAAAKRGGWRDFR
RFVVAKKVKESDVITSFYLKSEDGDAISDYLPGQYVSVKMSIPGETYTHIRQYSLSDAPGKGYYRISVKREAATADKPAG
IVSNYLHDHIQEGDVLELSAPAGDFTLDLAKETPVVFISGGVGITPLLSMANTLAIRQPNRPVTFLQAALNGRVQAFDQE
LQTLAKNPVFSYHICYESPSDEDRKHPHFSKEGRIDLEWMQTVIPSKDADFYFCGPVPFMKTVYRALKQWGVPEERIHYE
FFGPAGDLTKD
>Mature_410_residues
ATSTTLHPKTIEIVKSTVPVLEKHGEQITKRFYELMFSNHPELLNVFNHAHQKQGRQPRALAAAVYAAARYIDQLDAILP
VVRQIGHKHRSLGIKPEQYPIVGKHLLLAIKDVLGDAATDEVIAAWAEAYEVIADVFIQVEQELYDEAAAKRGGWRDFRR
FVVAKKVKESDVITSFYLKSEDGDAISDYLPGQYVSVKMSIPGETYTHIRQYSLSDAPGKGYYRISVKREAATADKPAGI
VSNYLHDHIQEGDVLELSAPAGDFTLDLAKETPVVFISGGVGITPLLSMANTLAIRQPNRPVTFLQAALNGRVQAFDQEL
QTLAKNPVFSYHICYESPSDEDRKHPHFSKEGRIDLEWMQTVIPSKDADFYFCGPVPFMKTVYRALKQWGVPEERIHYEF
FGPAGDLTKD

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=400, Percent_Identity=45, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI1787658, Length=261, Percent_Identity=28.3524904214559, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787098, Length=229, Percent_Identity=27.9475982532751, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321673, Length=408, Percent_Identity=43.6274509803922, Blast_Score=289, Evalue=6e-79,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR001834
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 46119; Mature: 45988

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSTTLHPKTIEIVKSTVPVLEKHGEQITKRFYELMFSNHPELLNVFNHAHQKQGRQPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHH
ALAAAVYAAARYIDQLDAILPVVRQIGHKHRSLGIKPEQYPIVGKHLLLAIKDVLGDAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHH
DEVIAAWAEAYEVIADVFIQVEQELYDEAAAKRGGWRDFRRFVVAKKVKESDVITSFYLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEEE
SEDGDAISDYLPGQYVSVKMSIPGETYTHIRQYSLSDAPGKGYYRISVKREAATADKPAG
CCCCCHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHH
IVSNYLHDHIQEGDVLELSAPAGDFTLDLAKETPVVFISGGVGITPLLSMANTLAIRQPN
HHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHEEECCC
RPVTFLQAALNGRVQAFDQELQTLAKNPVFSYHICYESPSDEDRKHPHFSKEGRIDLEWM
CCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEHHHH
QTVIPSKDADFYFCGPVPFMKTVYRALKQWGVPEERIHYEFFGPAGDLTKD
HHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCC
>Mature Secondary Structure 
ATSTTLHPKTIEIVKSTVPVLEKHGEQITKRFYELMFSNHPELLNVFNHAHQKQGRQPR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHH
ALAAAVYAAARYIDQLDAILPVVRQIGHKHRSLGIKPEQYPIVGKHLLLAIKDVLGDAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHH
DEVIAAWAEAYEVIADVFIQVEQELYDEAAAKRGGWRDFRRFVVAKKVKESDVITSFYLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEEE
SEDGDAISDYLPGQYVSVKMSIPGETYTHIRQYSLSDAPGKGYYRISVKREAATADKPAG
CCCCCHHHHCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHH
IVSNYLHDHIQEGDVLELSAPAGDFTLDLAKETPVVFISGGVGITPLLSMANTLAIRQPN
HHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHEEECCC
RPVTFLQAALNGRVQAFDQELQTLAKNPVFSYHICYESPSDEDRKHPHFSKEGRIDLEWM
CCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEHHHH
QTVIPSKDADFYFCGPVPFMKTVYRALKQWGVPEERIHYEFFGPAGDLTKD
HHHCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10484179; 11058132 [H]