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The map label for this gene is sucD [H]

Identifier: 138894730

GI number: 138894730

Start: 1128735

End: 1129637

Strand: Direct

Name: sucD [H]

Synonym: GTNG_1062

Alternate gene names: 138894730

Gene position: 1128735-1129637 (Clockwise)

Preceding gene: 138894729

Following gene: 138894731

Centisome position: 31.79

GC content: 52.82

Gene sequence:

>903_bases
GTGAGCGTTTTTGTCAATAAAGACACGAAAGTGATTGTACAAGGAATTACCGGTTCGCAAGGGCTGTTCCATACAAAACA
GATGATTGAATACGGAACGAACATTGTCGGTGGTGTCACGCCGGGCAAAGGTGGCACAGAAGTCGAAGGCGTGCCGGTGT
TTGACACTGTTTCGGAAGCGGTGGAAAAAACAGGAGCGAATGCTTCGGTTATTTACGTTCCGCCGGCGTTCGCTGCGGAT
GCCATCATGGAGGCAGTCGACGCCGAACTCGACCTTGTCGTCTGCATTACCGAAGGCATTCCGGTGCTCGATATGGTAAA
AGTGAAACGGTACATGGAAGGCAAAAAGACACGCCTTATCGGGCCAAACTGCCCGGGTGTCATTACGCCGGAAGAGTGCA
AAATCGGCATTATGCCGGGCTATATCCATAAAAAAGGGCATGTCGGCATCGTCTCGCGCTCTGGAACGCTGACGTATGAG
GCGGTTCACCAATTGACACAAGCCGGCATCGGCCAATCGACAGCGGTCGGCATCGGCGGCGACCCGGTCAACGGCACCAA
CTTTATCGACGTGTTGAAGGCGTTCAATGAAGACGATGAGACGTATGCGGTCATTATGATCGGTGAAATCGGCGGTACGG
CTGAAGAAGAAGCGGCGGAATGGGTGAAAGCAAACATGACGAAGCCGGTCGTCGGCTTTATCGGCGGACAAACAGCTCCT
CCGGGCAAACGGATGGGACATGCCGGCGCCATCATTTCCGGCGGCAAAGGTACGGCTGCGGAAAAAATTAAAAAAATGAA
CGAATGCGGCATCAAAGTGGCGGAAACACCGGCCGTCATTGGGGAAACGCTCATTTCCGTCCTGAAAGAGCGCGGATTGT
ACGAAAAATGCAAAACGCATTAA

Upstream 100 bases:

>100_bases
TTTTGCAAGAGTCGGGCTTGAACATTACGGCAGCTGAATCGATGGCAGATGGTGCGCAAAAAATCGTCGAGCTAGTACGT
TAAGAAAGCGAGGGAGACAT

Downstream 100 bases:

>100_bases
TGGTTCTACCCCGCACGATCATCACGTGCGGGGTGCTGTTTATCATGTTGCGAGAAAGGAGAATACGATGTACGATACGG
TCCGTGACCGGCTCATCCAT

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSVFVNKDTKVIVQGITGSQGLFHTKQMIEYGTNIVGGVTPGKGGTEVEGVPVFDTVSEAVEKTGANASVIYVPPAFAAD
AIMEAVDAELDLVVCITEGIPVLDMVKVKRYMEGKKTRLIGPNCPGVITPEECKIGIMPGYIHKKGHVGIVSRSGTLTYE
AVHQLTQAGIGQSTAVGIGGDPVNGTNFIDVLKAFNEDDETYAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
PGKRMGHAGAIISGGKGTAAEKIKKMNECGIKVAETPAVIGETLISVLKERGLYEKCKTH

Sequences:

>Translated_300_residues
MSVFVNKDTKVIVQGITGSQGLFHTKQMIEYGTNIVGGVTPGKGGTEVEGVPVFDTVSEAVEKTGANASVIYVPPAFAAD
AIMEAVDAELDLVVCITEGIPVLDMVKVKRYMEGKKTRLIGPNCPGVITPEECKIGIMPGYIHKKGHVGIVSRSGTLTYE
AVHQLTQAGIGQSTAVGIGGDPVNGTNFIDVLKAFNEDDETYAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
PGKRMGHAGAIISGGKGTAAEKIKKMNECGIKVAETPAVIGETLISVLKERGLYEKCKTH
>Mature_299_residues
SVFVNKDTKVIVQGITGSQGLFHTKQMIEYGTNIVGGVTPGKGGTEVEGVPVFDTVSEAVEKTGANASVIYVPPAFAADA
IMEAVDAELDLVVCITEGIPVLDMVKVKRYMEGKKTRLIGPNCPGVITPEECKIGIMPGYIHKKGHVGIVSRSGTLTYEA
VHQLTQAGIGQSTAVGIGGDPVNGTNFIDVLKAFNEDDETYAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAPP
GKRMGHAGAIISGGKGTAAEKIKKMNECGIKVAETPAVIGETLISVLKERGLYEKCKTH

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=296, Percent_Identity=63.5135135135135, Blast_Score=319, Evalue=2e-87,
Organism=Homo sapiens, GI38569423, Length=254, Percent_Identity=28.740157480315, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI38569421, Length=254, Percent_Identity=28.740157480315, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=64.7058823529412, Blast_Score=373, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17550194, Length=289, Percent_Identity=65.0519031141868, Blast_Score=358, Evalue=2e-99,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=60.958904109589, Blast_Score=343, Evalue=7e-95,
Organism=Caenorhabditis elegans, GI17557344, Length=314, Percent_Identity=25.796178343949, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=309, Percent_Identity=24.5954692556634, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=293, Percent_Identity=49.8293515358362, Blast_Score=275, Evalue=5e-75,
Organism=Drosophila melanogaster, GI21356559, Length=286, Percent_Identity=59.4405594405594, Blast_Score=351, Evalue=3e-97,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=58.4192439862543, Blast_Score=310, Evalue=6e-85,
Organism=Drosophila melanogaster, GI281363477, Length=254, Percent_Identity=28.3464566929134, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281363475, Length=254, Percent_Identity=28.3464566929134, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281363473, Length=254, Percent_Identity=28.3464566929134, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31445; Mature: 31314

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFVNKDTKVIVQGITGSQGLFHTKQMIEYGTNIVGGVTPGKGGTEVEGVPVFDTVSEA
CEEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCHHHHHHHH
VEKTGANASVIYVPPAFAADAIMEAVDAELDLVVCITEGIPVLDMVKVKRYMEGKKTRLI
HHHCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITPEECKIGIMPGYIHKKGHVGIVSRSGTLTYEAVHQLTQAGIGQSTAVGIGG
CCCCCCCCCCCCCEEECCCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
DPVNGTNFIDVLKAFNEDDETYAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
CCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
PGKRMGHAGAIISGGKGTAAEKIKKMNECGIKVAETPAVIGETLISVLKERGLYEKCKTH
CCCCCCCCCCEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
SVFVNKDTKVIVQGITGSQGLFHTKQMIEYGTNIVGGVTPGKGGTEVEGVPVFDTVSEA
EEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCHHHHHHHH
VEKTGANASVIYVPPAFAADAIMEAVDAELDLVVCITEGIPVLDMVKVKRYMEGKKTRLI
HHHCCCCCEEEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEE
GPNCPGVITPEECKIGIMPGYIHKKGHVGIVSRSGTLTYEAVHQLTQAGIGQSTAVGIGG
CCCCCCCCCCCCCEEECCCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
DPVNGTNFIDVLKAFNEDDETYAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
CCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
PGKRMGHAGAIISGGKGTAAEKIKKMNECGIKVAETPAVIGETLISVLKERGLYEKCKTH
CCCCCCCCCCEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]