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The map label for this gene is sucC [H]

Identifier: 138894729

GI number: 138894729

Start: 1127557

End: 1128717

Strand: Direct

Name: sucC [H]

Synonym: GTNG_1061

Alternate gene names: 138894729

Gene position: 1127557-1128717 (Clockwise)

Preceding gene: 138894728

Following gene: 138894730

Centisome position: 31.76

GC content: 50.04

Gene sequence:

>1161_bases
ATGAACATTCATGAATACCAAGCAAAAGAAATTTTGCGAAGCTATGGCGTAAGTGTGCCGAACGGTCGTGTTGCGTTCAC
GGTCGATGAAGCAGTTGAAGCGGCGAAAGCACTCGGCACGTCGGTGTGCGTCGTTAAGGCTCAAATTCATGCCGGCGGAC
GCGGCAAAGCAGGCGGGGTGAAAGTGGCCAAAAGCTTAGAGGAAGTCCGTACATACGCCAGCGAATTGCTTGGCAAAGTG
CTCGTCACCCATCAAACCGGTCCGGAAGGAAAAGAAGTCAAACGGCTTCTTATTGAAGAAGGATGCGACATCCAAAAAGA
ATATTACATTGGCCTTGTCGTCGACCGCGCCACCTCGCGCGTCGTCTTAATGGGCTCGGAAGAAGGCGGCACGGAAATCG
AAGAAGTAGCGGCGAAGACACCGGAGAAAATTTTTAAAGAATACGTCGATCCGGCGGTCGGATTGCAAGCGTTCCAAGCA
CGCCGCCTGGCGTTCAACATCAACATCCCGAAAAAACTTGTCAACCAAGCCGTAAAATTTATGATGGGCTTGTATCAAGT
GTTTGTCGATAAAGACTGCTCGATCGCTGAAATCAATCCGCTTGTCGTTACCGGCGACGGCAAAGTGATGGCGCTCGATG
CGAAATTGAACTTCGATTCAAACGCCTTGTATCGCCATCCGGATATTATGGAATACCGTGATTTGGATGAGGAAGATCCA
AAAGAAGTCGAAGCGTCGAAATATGATTTGAACTACATCGCCCTTGATGGTAACATCGGCTGCATGGTCAACGGTGCTGG
CTTGGCCATGGCGACGATGGACATCATCAAATATTACGGCGGCGAGCCGGCTAACTTCCTCGATGTTGGCGGCGGCGCTA
GCGAGGAAAAAGTGACGGAAGCATTCAAAATCATTTTGTCTGACCCGAATGTTAAAGGCATTTTCGTCAATATTTTCGGC
GGCATTATGAAATGTGATGTCATCGCCAGCGGCATTGTCGCAGCGACGAAGCAAGTCGGCTTGACACTTCCGCTCGTCGT
CCGGCTTGAAGGAACGAACGTCGAACTCGGGAAAAAGATTTTGCAAGAGTCGGGCTTGAACATTACGGCAGCTGAATCGA
TGGCAGATGGTGCGCAAAAAATCGTCGAGCTAGTACGTTAA

Upstream 100 bases:

>100_bases
ATTTCTTAATTTTGCGGCGAAACGGTGGACAACCAGGAAACGTTAGGTATAAAATGAAAGCGCTAAGACTTTTTTTAGTT
TATACATAGGAGGTTGGCGC

Downstream 100 bases:

>100_bases
GAAAGCGAGGGAGACATGTGAGCGTTTTTGTCAATAAAGACACGAAAGTGATTGTACAAGGAATTACCGGTTCGCAAGGG
CTGTTCCATACAAAACAGAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKEILRSYGVSVPNGRVAFTVDEAVEAAKALGTSVCVVKAQIHAGGRGKAGGVKVAKSLEEVRTYASELLGKV
LVTHQTGPEGKEVKRLLIEEGCDIQKEYYIGLVVDRATSRVVLMGSEEGGTEIEEVAAKTPEKIFKEYVDPAVGLQAFQA
RRLAFNINIPKKLVNQAVKFMMGLYQVFVDKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRHPDIMEYRDLDEEDP
KEVEASKYDLNYIALDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGGASEEKVTEAFKIILSDPNVKGIFVNIFG
GIMKCDVIASGIVAATKQVGLTLPLVVRLEGTNVELGKKILQESGLNITAAESMADGAQKIVELVR

Sequences:

>Translated_386_residues
MNIHEYQAKEILRSYGVSVPNGRVAFTVDEAVEAAKALGTSVCVVKAQIHAGGRGKAGGVKVAKSLEEVRTYASELLGKV
LVTHQTGPEGKEVKRLLIEEGCDIQKEYYIGLVVDRATSRVVLMGSEEGGTEIEEVAAKTPEKIFKEYVDPAVGLQAFQA
RRLAFNINIPKKLVNQAVKFMMGLYQVFVDKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRHPDIMEYRDLDEEDP
KEVEASKYDLNYIALDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGGASEEKVTEAFKIILSDPNVKGIFVNIFG
GIMKCDVIASGIVAATKQVGLTLPLVVRLEGTNVELGKKILQESGLNITAAESMADGAQKIVELVR
>Mature_386_residues
MNIHEYQAKEILRSYGVSVPNGRVAFTVDEAVEAAKALGTSVCVVKAQIHAGGRGKAGGVKVAKSLEEVRTYASELLGKV
LVTHQTGPEGKEVKRLLIEEGCDIQKEYYIGLVVDRATSRVVLMGSEEGGTEIEEVAAKTPEKIFKEYVDPAVGLQAFQA
RRLAFNINIPKKLVNQAVKFMMGLYQVFVDKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRHPDIMEYRDLDEEDP
KEVEASKYDLNYIALDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGGASEEKVTEAFKIILSDPNVKGIFVNIFG
GIMKCDVIASGIVAATKQVGLTLPLVVRLEGTNVELGKKILQESGLNITAAESMADGAQKIVELVR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=391, Percent_Identity=48.849104859335, Blast_Score=371, Evalue=1e-103,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=48.3028720626632, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=48.0662983425414, Blast_Score=327, Evalue=8e-90,
Organism=Escherichia coli, GI1786948, Length=385, Percent_Identity=56.6233766233766, Blast_Score=437, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=47.3145780051151, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.1025641025641, Blast_Score=320, Evalue=9e-88,
Organism=Saccharomyces cerevisiae, GI6321683, Length=396, Percent_Identity=44.4444444444444, Blast_Score=347, Evalue=2e-96,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=46.3104325699746, Blast_Score=342, Evalue=2e-94,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=46.3104325699746, Blast_Score=342, Evalue=2e-94,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=46.4467005076142, Blast_Score=341, Evalue=6e-94,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=46.4467005076142, Blast_Score=341, Evalue=6e-94,
Organism=Drosophila melanogaster, GI21356231, Length=390, Percent_Identity=45.6410256410256, Blast_Score=325, Evalue=4e-89,
Organism=Drosophila melanogaster, GI281363477, Length=407, Percent_Identity=25.3071253071253, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363475, Length=407, Percent_Identity=25.3071253071253, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281363473, Length=407, Percent_Identity=25.3071253071253, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41669; Mature: 41669

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50975 ATP_GRASP ; PS00063 ALDOKETO_REDUCTASE_3 ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILRSYGVSVPNGRVAFTVDEAVEAAKALGTSVCVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHH
KVAKSLEEVRTYASELLGKVLVTHQTGPEGKEVKRLLIEEGCDIQKEYYIGLVVDRATSR
HHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCE
VVLMGSEEGGTEIEEVAAKTPEKIFKEYVDPAVGLQAFQARRLAFNINIPKKLVNQAVKF
EEEEECCCCCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHCEEEEEECCCCHHHHHHHHHH
MMGLYQVFVDKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRHPDIMEYRDLDEEDP
HHHHHHHHHCCCCCEEECCCEEEECCCEEEEEEEEECCCCCCEECCCCCHHHCCCCCCCC
KEVEASKYDLNYIALDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGGASEEKVTE
CHHCCCEECEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDPNVKGIFVNIFGGIMKCDVIASGIVAATKQVGLTLPLVVRLEGTNVELGKKI
HHHHEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHH
LQESGLNITAAESMADGAQKIVELVR
HHHCCCCEEEHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNIHEYQAKEILRSYGVSVPNGRVAFTVDEAVEAAKALGTSVCVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCHH
KVAKSLEEVRTYASELLGKVLVTHQTGPEGKEVKRLLIEEGCDIQKEYYIGLVVDRATSR
HHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCE
VVLMGSEEGGTEIEEVAAKTPEKIFKEYVDPAVGLQAFQARRLAFNINIPKKLVNQAVKF
EEEEECCCCCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHCEEEEEECCCCHHHHHHHHHH
MMGLYQVFVDKDCSIAEINPLVVTGDGKVMALDAKLNFDSNALYRHPDIMEYRDLDEEDP
HHHHHHHHHCCCCCEEECCCEEEECCCEEEEEEEEECCCCCCEECCCCCHHHCCCCCCCC
KEVEASKYDLNYIALDGNIGCMVNGAGLAMATMDIIKYYGGEPANFLDVGGGASEEKVTE
CHHCCCEECEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDPNVKGIFVNIFGGIMKCDVIASGIVAATKQVGLTLPLVVRLEGTNVELGKKI
HHHHEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHH
LQESGLNITAAESMADGAQKIVELVR
HHHCCCCEEEHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA