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The map label for this gene is hlyB [H]

Identifier: 138894333

GI number: 138894333

Start: 740106

End: 741062

Strand: Direct

Name: hlyB [H]

Synonym: GTNG_0661

Alternate gene names: 138894333

Gene position: 740106-741062 (Clockwise)

Preceding gene: 138894331

Following gene: 138894334

Centisome position: 20.85

GC content: 51.31

Gene sequence:

>957_bases
ATGTGGCCGTTGGTGAAAGGACGGCAGTGGGAGGAGGAAAAAGCGAAGCTAGAGCAACAAATCGCCGAGATGAAAGACCA
GCTCACTAGACAGAAGGAATCGATTCACGAGACGGTGGCCGGCTTGCTCGGGGAGTTGCAGGAAATCGTTCATCAACATG
AGGTGGTCAACGGACAACATCATGCATTAGGCCGACTCGTTGACCGAACGAAAGAAAAAGTCGATAATGTCAGTACGCTC
AGCAAGTCATCATACGCGATCTCCGACCGTCTGTGCGAACAAGGAAACTCGTTGGCGGAGACAGCTGGCCAGATGGTCGC
GGCAGCAAAAGAAGGCATCCGCATGTCAGGGGAAATGGAGAAGGCGATGGGGCAGCTCGGCAGCGAGATGGAGGCGACGT
CGGCCGCAATGTATCGGTTGCGCGGCCGTTCGCAAGAGATTGAACAAATTGTGAAAGTAATTAAAGAAATCGCTGGACAG
ACAAATTTGATTGCATTAAATGCCTCGATCGAAGCCGCCCGTGCCGGGGAGCATGGAAAAGGGTTTTCCGTCGTCGCTGC
TGAAGTGAGAAAGTTGGCTGAGCATACGGCGGACAGCACGGAAACGATTCATCAGTTAACCGATGCCGTGCAGCAGGAAA
TTGAGCGGTCGCTAGAGCAGACGGAAGCTATTTCGTCTTTGATCGAAACGGTTGTCCAAATGAGCATCCATACAGCTCGC
AAATGGTCGGCGATGAGGGAGCTGATCGATCAAGTCGAAAATCGGGCCAAGGACGTGCTAAACTATATTCAAGAACAATA
CCGCTATGCGGATGAAGTGATGCAAGAGCTCGAACAATCGGCCTCTTTGTTCAGCGAAACGCGGGAGATGATTTTGCGAC
ATATTGCCGATGCGAGTGTTGTTGATGAAAAGTTGGCAGAAGGCATCAAACAGCTGCAACAATGGCAACAACGTTAA

Upstream 100 bases:

>100_bases
AAGTGTCCGCTTCATAATCGAAAGAATACATGCTCAGTAGGTAACATACAACATTTTGACAAAAGAATGAGTTCCATAAA
CAGAAAAAGGGGAGACGGGT

Downstream 100 bases:

>100_bases
AAGAATGATATCGTTGCCGCCAGCCGTAGGATCGAAAGGAGAGAGAGACATGGTCGAAAGACGAACCCCGATTCCCGTAG
CGGAAGCGATCAATCGGGTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MWPLVKGRQWEEEKAKLEQQIAEMKDQLTRQKESIHETVAGLLGELQEIVHQHEVVNGQHHALGRLVDRTKEKVDNVSTL
SKSSYAISDRLCEQGNSLAETAGQMVAAAKEGIRMSGEMEKAMGQLGSEMEATSAAMYRLRGRSQEIEQIVKVIKEIAGQ
TNLIALNASIEAARAGEHGKGFSVVAAEVRKLAEHTADSTETIHQLTDAVQQEIERSLEQTEAISSLIETVVQMSIHTAR
KWSAMRELIDQVENRAKDVLNYIQEQYRYADEVMQELEQSASLFSETREMILRHIADASVVDEKLAEGIKQLQQWQQR

Sequences:

>Translated_318_residues
MWPLVKGRQWEEEKAKLEQQIAEMKDQLTRQKESIHETVAGLLGELQEIVHQHEVVNGQHHALGRLVDRTKEKVDNVSTL
SKSSYAISDRLCEQGNSLAETAGQMVAAAKEGIRMSGEMEKAMGQLGSEMEATSAAMYRLRGRSQEIEQIVKVIKEIAGQ
TNLIALNASIEAARAGEHGKGFSVVAAEVRKLAEHTADSTETIHQLTDAVQQEIERSLEQTEAISSLIETVVQMSIHTAR
KWSAMRELIDQVENRAKDVLNYIQEQYRYADEVMQELEQSASLFSETREMILRHIADASVVDEKLAEGIKQLQQWQQR
>Mature_318_residues
MWPLVKGRQWEEEKAKLEQQIAEMKDQLTRQKESIHETVAGLLGELQEIVHQHEVVNGQHHALGRLVDRTKEKVDNVSTL
SKSSYAISDRLCEQGNSLAETAGQMVAAAKEGIRMSGEMEKAMGQLGSEMEATSAAMYRLRGRSQEIEQIVKVIKEIAGQ
TNLIALNASIEAARAGEHGKGFSVVAAEVRKLAEHTADSTETIHQLTDAVQQEIERSLEQTEAISSLIETVVQMSIHTAR
KWSAMRELIDQVENRAKDVLNYIQEQYRYADEVMQELEQSASLFSETREMILRHIADASVVDEKLAEGIKQLQQWQQR

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=137, Percent_Identity=37.956204379562, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788194, Length=207, Percent_Identity=32.3671497584541, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788195, Length=201, Percent_Identity=31.8407960199005, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI2367378, Length=141, Percent_Identity=38.2978723404255, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787690, Length=160, Percent_Identity=33.125, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 35774; Mature: 35774

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWPLVKGRQWEEEKAKLEQQIAEMKDQLTRQKESIHETVAGLLGELQEIVHQHEVVNGQH
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HALGRLVDRTKEKVDNVSTLSKSSYAISDRLCEQGNSLAETAGQMVAAAKEGIRMSGEME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHH
KAMGQLGSEMEATSAAMYRLRGRSQEIEQIVKVIKEIAGQTNLIALNASIEAARAGEHGK
HHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCC
GFSVVAAEVRKLAEHTADSTETIHQLTDAVQQEIERSLEQTEAISSLIETVVQMSIHTAR
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWSAMRELIDQVENRAKDVLNYIQEQYRYADEVMQELEQSASLFSETREMILRHIADASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDEKLAEGIKQLQQWQQR
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWPLVKGRQWEEEKAKLEQQIAEMKDQLTRQKESIHETVAGLLGELQEIVHQHEVVNGQH
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HALGRLVDRTKEKVDNVSTLSKSSYAISDRLCEQGNSLAETAGQMVAAAKEGIRMSGEME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHH
KAMGQLGSEMEATSAAMYRLRGRSQEIEQIVKVIKEIAGQTNLIALNASIEAARAGEHGK
HHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHCCCCCC
GFSVVAAEVRKLAEHTADSTETIHQLTDAVQQEIERSLEQTEAISSLIETVVQMSIHTAR
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWSAMRELIDQVENRAKDVLNYIQEQYRYADEVMQELEQSASLFSETREMILRHIADASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDEKLAEGIKQLQQWQQR
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]