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The map label for this gene is fnr [H]

Identifier: 138894329

GI number: 138894329

Start: 736333

End: 737058

Strand: Reverse

Name: fnr [H]

Synonym: GTNG_0657

Alternate gene names: 138894329

Gene position: 737058-736333 (Counterclockwise)

Preceding gene: 138894332

Following gene: 138894323

Centisome position: 20.76

GC content: 45.45

Gene sequence:

>726_bases
ATGGAGGTGTCAATCATGGAACGGCAAAGCCGCACAGCGGCGAACCGCGATTTTTCCCTCTTGCGCTCATGGCTGCAATC
GTCGAAAAAAGTGATCCCGCTTCGCAAACATTCGTTTTTATTTCAAGAAGGGATGCCCGCCAATGAGCTGTATTTGATTC
TGTCCGGCAAGGTGCAAGTAAGCAAAATTTGTCCGGACGGAAAAGAAATGTGTTTCCGCATTTGTGGAAGCGGGGAAATT
GTCGGCGAACTGACGCTGTTTACGGACGATCCACGTTATTTATTGACCGCCAAAGTGATTGAACCGGGTGAAGCAGCGGT
AATGAATAAAAATGAATTAGAAGAGCAGTTGCTGATCAATCCCACCCTTACCCTTGAATATATGCGCTGGATCAGCAAGC
ATGCCCGACGGACGCAAACAAAGTTTCGTGACTTGATTATGAACGGCAAAAAAGGGGCGCTCTATTCAACACTTATTCGC
TTATGCAACAGTTATGGCGTCCCGCTTGAAGACGGAAGCATCTTCATTGATTTAACGTTAAAAAACCAAGACTTGGCCAA
CTTTTGCGGCACGACGCGTGAAAGCGTCAATCGGATGCTCAATGCATTAAAGCAAGACGGAATTATTTCGATGAAGCGAG
GGAAAATTACTGTTCACGACTTGAACTATTTAAAAACGGAAATCCAATGTGAAGACTGCCCGCCAGACATTTGTTGCATT
GAATAA

Upstream 100 bases:

>100_bases
TAGAAAAATTTGTGACAACCTGCACAAAAAAGTGGCAAAGGGTGATTTTTTTCACTCTGTCTCTGCTGTGATTTTTTTTA
CAATAGAATTAGCCGAACAA

Downstream 100 bases:

>100_bases
AATGAACAAAACTTAGAGGGCTGTCCTAAAAGAGTTACCCCCCTTTATGGACAGCCCTGCTTTTTCCCTAAATTTTTTTC
GCCCGCATCCGGCGATAGAC

Product: Crp family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MEVSIMERQSRTAANRDFSLLRSWLQSSKKVIPLRKHSFLFQEGMPANELYLILSGKVQVSKICPDGKEMCFRICGSGEI
VGELTLFTDDPRYLLTAKVIEPGEAAVMNKNELEEQLLINPTLTLEYMRWISKHARRTQTKFRDLIMNGKKGALYSTLIR
LCNSYGVPLEDGSIFIDLTLKNQDLANFCGTTRESVNRMLNALKQDGIISMKRGKITVHDLNYLKTEIQCEDCPPDICCI
E

Sequences:

>Translated_241_residues
MEVSIMERQSRTAANRDFSLLRSWLQSSKKVIPLRKHSFLFQEGMPANELYLILSGKVQVSKICPDGKEMCFRICGSGEI
VGELTLFTDDPRYLLTAKVIEPGEAAVMNKNELEEQLLINPTLTLEYMRWISKHARRTQTKFRDLIMNGKKGALYSTLIR
LCNSYGVPLEDGSIFIDLTLKNQDLANFCGTTRESVNRMLNALKQDGIISMKRGKITVHDLNYLKTEIQCEDCPPDICCI
E
>Mature_241_residues
MEVSIMERQSRTAANRDFSLLRSWLQSSKKVIPLRKHSFLFQEGMPANELYLILSGKVQVSKICPDGKEMCFRICGSGEI
VGELTLFTDDPRYLLTAKVIEPGEAAVMNKNELEEQLLINPTLTLEYMRWISKHARRTQTKFRDLIMNGKKGALYSTLIR
LCNSYGVPLEDGSIFIDLTLKNQDLANFCGTTRESVNRMLNALKQDGIISMKRGKITVHDLNYLKTEIQCEDCPPDICCI
E

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=199, Percent_Identity=26.1306532663317, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27432; Mature: 27432

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVSIMERQSRTAANRDFSLLRSWLQSSKKVIPLRKHSFLFQEGMPANELYLILSGKVQV
CCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEECCHHHHHHHHCCCCCCEEEEEEECCEEE
SKICPDGKEMCFRICGSGEIVGELTLFTDDPRYLLTAKVIEPGEAAVMNKNELEEQLLIN
EECCCCHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEEEECCCCCEECCHHHHHHHHCCC
PTLTLEYMRWISKHARRTQTKFRDLIMNGKKGALYSTLIRLCNSYGVPLEDGSIFIDLTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEE
KNQDLANFCGTTRESVNRMLNALKQDGIISMKRGKITVHDLNYLKTEIQCEDCPPDICCI
CCCHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCEEEEEEHHHHHEEEEECCCCCCCEEC
E
C
>Mature Secondary Structure
MEVSIMERQSRTAANRDFSLLRSWLQSSKKVIPLRKHSFLFQEGMPANELYLILSGKVQV
CCCCHHHHHHHHHCCCCHHHHHHHHHCCCCEECCHHHHHHHHCCCCCCEEEEEEECCEEE
SKICPDGKEMCFRICGSGEIVGELTLFTDDPRYLLTAKVIEPGEAAVMNKNELEEQLLIN
EECCCCHHHHHHHHCCCCCEEEEEEEEECCCCEEEEEEEECCCCCEECCHHHHHHHHCCC
PTLTLEYMRWISKHARRTQTKFRDLIMNGKKGALYSTLIRLCNSYGVPLEDGSIFIDLTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEE
KNQDLANFCGTTRESVNRMLNALKQDGIISMKRGKITVHDLNYLKTEIQCEDCPPDICCI
CCCHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCEEEEEEHHHHHEEEEECCCCCCCEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]